Article
Multidisciplinary Sciences
Jeremy Di Mattia, Babil Torralba, Michel Yvon, Jean-Louis Zeddam, Stephane Blanc, Yannis Michalakis
Summary: Multipartite viruses can reduce the cost of genome integrity by transmitting and complementing different genome segments between hosts.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Review
Veterinary Sciences
Souvik Ghosh, Yashpal S. Malik
Summary: Picobirnaviruses are bisegmented double-stranded RNA viruses detected in a wide range of animal species and environmental samples. There is ongoing debate about the true host of these viruses.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Multidisciplinary Sciences
Laura M. Bergner, Richard J. Orton, Alice Broos, Carlos Tello, Daniel J. Becker, Jorge E. Carrera, Arvind H. Patel, Roman Biek, Daniel G. Streicker
Summary: Research shows that deltaviruses diversify by transmitting between different mammalian species, with a recent diversification indicated within the Americas. Both bat and rodent-infecting deltaviruses were paraphyletic, and co-evolutionary modeling rejected cospeciation with mammalian hosts. A two-year field study revealed multiple introductions of divergent deltaviruses to common vampire bats in Peru, illustrating horizontal transmission within and between species.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Review
Immunology
Shuang Tang, Jie Li, Yung-Fu Chang, Wencheng Lin
Summary: Avian leukosis virus (ALV) causes various diseases, including tumor formation and decreased fertility. In addition, ALV induces immunosuppression, increasing susceptibility to other microbial infections and the risk of vaccine failure against other diseases. Evidence shows an interaction between ALV and the host.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Microbiology
Shwetha Shivaprasad, Peter Sarnow
Summary: This review article focuses on how pathogenic RNA viruses utilize host biochemical machineries and specific RNA elements in the untranslated regions to achieve viral infection cycles and enhance viral fitness.
CURRENT OPINION IN MICROBIOLOGY
(2021)
Article
Biochemical Research Methods
Bill Lee, David K. Smith, Yi Guan
Summary: The study used machine learning models to predict the reservoir hosts of viruses, combining sequence alignment and gradient boosting machines to improve prediction accuracy.
Article
Plant Sciences
Ho-Hsiung Chang, Deri Gustian, Chung-Jan Chang, Fuh-Jyh Jan
Summary: This study found that mixed infection affects the mechanical transmissibility and host range of nonmechanically transmissible begomoviruses, ToLCNDV and TYLCTHV. These findings provide important insights into the complex virus-virus interactions and have implications for disease management strategies in the field.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Yange Lang, Fangfang Li, Qiang Liu, Zhiqiang Xia, Zhenglin Ji, Juan Hu, Yuting Cheng, Minjun Gao, Fang Sun, Bingzheng Shen, Chang Xie, Wei Yi, Yingliang Wu, Jing Yao, Zhijian Cao
Summary: The functional Kv1.3 ion channel restricts the entry of HCV, DENV, and ZIKV by inhibiting endosome acidification-mediated viral membrane fusion, with no effect on SeV. The Kv1.3 antagonist PAP-1 accelerates animal death in ZIKV-infected Ifnar1(-/-) mice, and deletion of Kv1.3 promotes weight loss and reduces survival rate in ZIKV-infected Kv1.3(-/-) mice. Overall, the Kv1.3 ion channel acts as a host factor that limits viral entry and expands understanding of ion channel biology.
Review
Virology
Chuankuo Zhao, Juan Pu
Summary: Influenza viruses utilize sialic acid receptors to invade host cells, and factors such as sialic acid variants, glycan structural differences, and sulfation/fucosylation affect the specificity of viral host binding. Understanding these factors can contribute to the investigation of cross-species transmission of influenza viruses and the development of antiviral drugs.
Article
Biology
Izan Melero, Ruben Gonzalez, Santiago F. Elena
Summary: Viruses rely on hosts to complete their infectious cycle, and the developmental stage of the host plays a crucial role in host-virus interactions. This study showed that hosts in later developmental stages are more susceptible to severe infections. The genomic changes of the evolved viral lineages depended on the founder viral isolate and the developmental stage of the host.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2023)
Article
Multidisciplinary Sciences
Mark J. G. Bakkers, Alex Moon-Walker, Rasmus Herlo, Vesna Brusic, Sarah Hulsey Stubbs, Kathryn M. Hastie, Erica Ollmann Saphire, Tomas L. Kirchhausen, Sean P. J. Whelan
Summary: LCMV is a virus that enters cells by binding to different receptors and causes severe health problems. This study found that LCMV first binds to CD164 before entering cells, providing new targets for therapeutic interventions.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Review
Microbiology
Yinghua Su, Ting Lin, Chun Liu, Cui Cheng, Xiao Han, Xiwen Jiang
Summary: Dengue virus is transmitted by mosquitoes and can cause a range of symptoms from mild fever to life-threatening hemorrhagic fever and shock syndrome. miRNAs, important non-coding RNAs, play crucial roles in regulating gene expression and cell processes, including virus infections.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Joseph M. Dybas, Krystal K. Lum, Katarzyna Kulej, Emigdio D. Reyes, Richard Lauman, Matthew Charman, Caitlin E. Purman, Robert T. Steinbock, Nicholas Grams, Alexander M. Price, Lydia Mendoza, Benjamin A. Garcia, Matthew D. Weitzman
Summary: Viral infections cause extensive remodeling of the cellular proteome. This study developed a global proteomics approach to analyze changes in the host proteome during adenovirus serotype 5 (Ad5) virus infection. The results reveal cellular processes manipulated by viral products and host factors counteracted by early viral proteins during infection.
Article
Immunology
Gennady Bocharov, Dmitry Grebennikov, Paula Cebollada Rica, Eva Domenjo-Vila, Valentina Casella, Andreas Meyerhans
Summary: This study describes recent progress in the clinical handling of chronic virus infections and emphasizes the understanding of virus-host interaction dynamics as well as the involvement of multiple immune system components in functional cure strategies.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Microbiology
Michael S. Overton, Robert D. Manuel, C. Martin Lawrence, Jamie C. Snyder
Summary: Viruses play a crucial role in the evolution and ecology of cellular life. Studying viruses has greatly advanced our understanding of various aspects of living systems. Recent research on archaeal viruses has produced intriguing results, revealing their interactions with cells.
FRONTIERS IN MICROBIOLOGY
(2023)