Article
Endocrinology & Metabolism
Yannuo Li, Ioannis P. Androulakis
Summary: The suprachiasmatic nucleus (SCN) synchronizes physiological rhythms and adapts to changes in photoperiod, affecting the phase distribution of neuron activities. Elevated glucocorticoid levels in short photoperiods are associated with peak disease incidence. Topological changes in the SCN network may influence seasonal variations in disease incidence.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Psychiatry
Marina Xavier Carpena, Karen Yumaira Sanchez-Luquez, Thais Martins-Silva, Thiago M. Santos, Cid Pinheiro Farias, Daniel Gray Paschoal Leventhal, Barbara Berruti, Cristian Patrick Zeni, Marcelo Schmitz, Rodrigo Chazan, Mara H. Hutz, Angelica Salatino-Oliveira, Julia P. Genro, Luis Augusto Rohde, Luciana Tovo-Rodrigues
Summary: A recent study has identified a correlation between several single nucleotide polymorphisms (SNPs) in the SERPINA6 region and Attention Deficit/Hyperactivity Disorder (ADHD), suggesting a shared genetic component between cortisol levels and ADHD. The study also found that the expression of corticosteroid binding globulin (encoded by SERPINA6) may play a role in the dysregulation of the Hypothalamus-Pituitary-Adrenal (HPA) axis and altered stress response in ADHD.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Endocrinology & Metabolism
Cathy Degroote, Roland von Kanel, Livia Thomas, Claudia Zuccarella-Hackl, Nadine Messerli-Burgy, Hugo Saner, Roland Wiest, Petra H. Wirtz
Summary: Research shows that patients with coronary heart disease (CHD) and hypertension have decreased activity in the hypothalamus-pituitary-adrenal (HPA) axis, which may contribute to an increased risk of cardiovascular disease.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Clinical Neurology
Jelena Bakusic, Manosij Ghosh, Andrea Polli, Bram Bekaert, Wilmar Schaufeli, Stephan Claes, Lode Godderis
Summary: The study revealed that job stress was associated with increased levels of cortisol and cortisone in burnout participants. Changes in DNA methylation of the NR3C1 and SLC6A4 genes were observed in burnout individuals, and some of these methylation changes correlated with burnout symptoms. Increased methylation in a specific CpG in the SLC6A4 gene moderated the association between job stress and burnout, while DNA methylation in this CpG was also associated with increased cortisol levels. Furthermore, average methylation of NR3C1 was negatively associated with cortisone levels.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Endocrinology & Metabolism
Pauline S. Effenberger, Tabea S. Send, Maria Gilles, Josef Frank, Stephan Bongard, Robert Kumsta, Stephanie H. Witt, Marcella Rietschel, Michael Deuschle, Fabian Streit, Isabell A. C. Wolf
Summary: There is no strong association between urbanicity and behavior problems or HPA axis regulation in preschool age, and urinary cortisol and salivary cortisol response after stress exposure are not identified as mediators of this relationship.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Anne Berens, Joelle LeMoult, Katharina Kircanski, Ian H. Gotlib
Summary: This study examined the association between symptoms of attention deficit-hyperactivity disorder (ADHD) and diurnal cortisol output. It found that ADHD symptoms were significantly associated with higher cumulative diurnal cortisol, morning cortisol, and afternoon cortisol. However, symptoms of comorbid psychiatric disorders such as conduct disorder, anxiety, and depression did not show significant associations with cortisol levels.
PSYCHONEUROENDOCRINOLOGY
(2023)
Article
Behavioral Sciences
Harriet Smith, Chloe Lane, Reem Al-Jawahiri, Megan Freeth
Summary: The study assessed the sensory experiences of 38 children with a 16p11.2 deletion and 31 children with a 16p11.2 duplication. The frequency and impact of sensory behavior differences were profound, though there was significant variation within both groups. Overall, sensory behavior was found to be similar to autistic children. Over 70% of children in both groups failed to effectively register sensory information. 71% of children with a 16p11.2 duplication were highly sensitive to sensory information, and 57% were highly avoidant of sensory stimuli.
Article
Neurosciences
Trina Basu, Jamie Maguire, Jay A. Salpekar
Summary: Stress is a common seizure trigger in persons with epilepsy, and prolonged exposure to stress hormones may exacerbate epilepsy and increase the risk of psychiatric comorbidities. Hyperactivity of the HPA axis negatively impacts the structure and function of the temporal lobe, leading to neuronal damage and a cycle of increased susceptibility for seizures and psychiatric comorbidities. Targeting the HPA axis in treatment may improve seizure control and alleviate stress-related psychiatric comorbidities.
NEUROSCIENCE LETTERS
(2021)
Article
Endocrinology & Metabolism
Jessica L. Irwin, Amy L. Meyering, Gage Peterson, Laura M. Glynn, Curt A. Sandman, Laurel M. Hicks, Elysia Poggi Davis
Summary: The study investigated the relationship between maternal prenatal cortisol levels and infant cortisol reactivity during inoculation. The results showed that elevated prenatal cortisol levels in mothers are associated with a larger cortisol response in infants at 6 and 12 months when faced with a challenging event.
PSYCHONEUROENDOCRINOLOGY
(2021)
Review
Clinical Neurology
Raphael J. Dressle, Bernd Feige, Kai Spiegelhalder, Christine Schmucker, Fee Benz, Nina C. Mey, Dieter Riemann
Summary: This study aimed to evaluate the differences in cortisol levels, the hormonal end product of the HPA axis, between patients with insomnia and good sleeper controls. The results suggested that patients with insomnia showed moderately increased cortisol levels, with higher effect sizes found when analyzing studies that used blood samples. There was a positive but insignificant association between the extent of objective sleep loss in insomnia patients and group differences in cortisol levels.
SLEEP MEDICINE REVIEWS
(2022)
Article
Endocrinology & Metabolism
Lycia D. de Voogd, Rosalie Anne Kampen, Reinoud Kaldewaij, Wei Zhang, Mahur Melina Hashemi, Saskia B. J. Koch, Floris Klumpers, Jeffrey C. Glennon, Karin Roelofs
Summary: This study provides the first longitudinal evidence of a dose-response relationship between trauma and human GR mRNA expression changes, indicating that increased traumatic events during police training lead to stronger GR mRNA expression. Additionally, increases in GR mRNA expression are associated with blunted HPA-axis stress-reactivity.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
James L. Abelson, Brisa N. Sanchez, Stefanie E. Mayer, Hedieh Briggs, Israel Liberzon, Nirmala Rajaram
Summary: Salivary cortisol stress biomarkers are commonly used in epidemiological research to examine the relationship between stress and health problems. However, there has been limited effort to connect these measures with the biological mechanisms involved in stress-related health outcomes. This study found associations between cortisol diurnal decline and feedback sensitivity, as well as between morning cortisol levels and adrenal sensitivity. It also raised questions about the biological meaning of other curve components, such as morning cortisol levels and the cortisol awakening response.
PSYCHONEUROENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Andrea G. Roberts, Melissa K. Peckins, Arianna M. Gard, Tyler C. Hein, Felicia A. Hardi, Colter Mitchell, Christopher S. Monk, Luke W. Hyde, Nestor L. Lopez -Duran
Summary: Threat-related amygdala reactivity and HPA axis activation are linked to negative psychiatric outcomes. Enhanced amygdala activation in response to threat may be related to hyper-reactivity of the HPA axis.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Multidisciplinary Sciences
Nina E. Ahlers, Sandra J. Weiss
Summary: The study found that increased prenatal exposure to PM2.5 was associated with more severe depressive symptoms in the third trimester. Greater PM2.5 exposure was also linked to higher cortisol AUCG and average cortisol levels among women, though no cortisol parameter appeared to mediate the relationship between PM2.5 exposure and depressive symptoms.
Article
Psychology, Multidisciplinary
Evan E. Dean, Lauren Little, Scott Tomchek, Anna Wallisch, Winnie Dunn
Summary: Current research tends to view differences from expected patterns as problematic and associated with disabilities. However, this study found consistent sensory patterns across different groups, suggesting that differences in sensory processing may be part of natural variability rather than problematic behaviors.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Nursing
Regina Lai Tong Lee, Shelly Lane, Graeme Brown, Cynthia Leung, Stephen Wai Hang Kwok, Sally Wai Chi Chan
NURSING & HEALTH SCIENCES
(2020)
Review
Rehabilitation
Nathan C. Kerr, Samantha Ashby, Steven M. Gerardi, Shelly J. Lane
AUSTRALIAN OCCUPATIONAL THERAPY JOURNAL
(2020)
Correction
Environmental Sciences
Regina Lai Tong Lee, Shelly Jerrine Lane, Anson Chui Yan Tang, Cynthia Leung, Stephen Wai Hang Kwok, Lobo Hung Tak Louie, Graeme Browne, Sally Wai Chi Chan
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Review
Rehabilitation
Susan Allen, Fiona J. Knott, Amanda Branson, Shelly J. Lane
Summary: This review examined the effectiveness of occupational therapy coaching interventions for parents of children with sensory integration difficulties. It found that individual coaching can positively impact child goals, parental stress, and sense of competence, while group interventions can improve caregivers' knowledge of sensory integration and self-efficacy in dealing with sensory-related behaviors.
OCCUPATIONAL THERAPY INTERNATIONAL
(2021)
Article
Psychology, Developmental
Kelle K. DeBoth, Stacey Reynolds, Shelly J. Lane, Henry Carretta, Alison E. Lane, Roseann C. Schaaf
Summary: Children with autism spectrum disorder show atypical behavioral responses to sensory stimuli and differences in autonomic nervous system and neuroendocrine activity. Sensory-based subtypes may help to understand these differences. This study found that changes in physiological indicators during sensory stimulation and recovery periods can predict subtype membership.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Review
Psychology, Multidisciplinary
Shelly J. Lane, Marco A. Leao, Virginia Spielmann
Summary: The prevalence of sleep dysfunction is higher in autistic population compared to non-autistic population. Sensory integration/processing concerns may contribute to sleep disorders in autism. However, research on the interplay between sleep and sensory integration/processing in autistic individuals is limited.
FRONTIERS IN PSYCHOLOGY
(2022)
Editorial Material
Behavioral Sciences
Sarah A. Schoen, Roseann C. Schaaf, Zoe Mailloux, Anita Bundy, Shelly Lane, Teresa A. May-Benson, L. Diane Parham, Susanne Smith Roley
FRONTIERS IN INTEGRATIVE NEUROSCIENCE
(2022)
Article
Rehabilitation
Tracy M. Stackhouse, Hannah K. Burke, Colleen G. Hacker, Lynette M. Burke, Caroline E. Hui, Beth Osten, Shelly J. Lane
Summary: This study examines the effects of integrating occupational therapy into a camp setting for children with regulation/sensory processing differences. The results show that there was significant improvement in occupational performance during the camp, which exceeded the change observed in the three months prior. The improvements remained stable three months after the camp, suggesting the benefits of integrating occupational therapy into a camp environment for children with neurodevelopmental differences.
CANADIAN JOURNAL OF OCCUPATIONAL THERAPY-REVUE CANADIENNE D ERGOTHERAPIE
(2023)
Review
Pediatrics
Hannah K. Burke, Lynette M. Burke, Colleen G. Hacker, Shelly J. Lane
Summary: This scoping review aimed to explore the extent of nature-based interventions used in pediatric occupational therapy and to identify gaps in existing literature. The review found a lack of clear conceptualization of nature-based practices and a lack of articulation of the unique contribution of occupational therapy to such practices in the field.
PHYSICAL & OCCUPATIONAL THERAPY IN PEDIATRICS
(2023)
Article
Rehabilitation
Kayley Goertzen, Shelly J. Lane, Paula Yuma, Jennifer Reinke, Anita Bundy
Summary: The study evaluated the construct validity, internal reliability, and cross-cultural validity of a parental playfulness attitude assessment scale in Latino-American caregivers. The results showed that the scale had adequate validity and reliability, and it was also valid across different cultural backgrounds.
AMERICAN JOURNAL OF OCCUPATIONAL THERAPY
(2023)
Review
Rehabilitation
Virginia Spielmann, Hannah K. Burke, Sarah McCulloch, Alex Mason, Shelly J. Lane
Summary: This survey explores the relationship between sensory integration and processing differences and mental health concerns reported by autistic adults through a retrospective analysis of internet-based survey data. The results show that both SI/P disruptions and sensory sensitivity are significant predictors of anxiety and depression. This highlights the importance of sensory integration and processing for the mental health of autistic adults.
AMERICAN JOURNAL OF OCCUPATIONAL THERAPY
(2023)
Article
Social Sciences, Interdisciplinary
Nathan C. Kerr, Shelly J. Lane, Ronald C. Plotnikoff, Samantha Ashby
Summary: Internationally, it is recognized that a military identity poses challenges to the transition from military service to civilian life. This study explores the impact of an occupational military identity on this transition, from the perspective of former Australian Defence Force members. The findings reveal both the challenges and positive aspects of a military identity, providing insights on how to facilitate a successful transition.
JOURNAL OF OCCUPATIONAL SCIENCE
(2023)
Review
Rehabilitation
Lisa M. Porter, Shelly J. Lane, Barbara B. Demchick, Jane K. Sweeney, Pamela A. Mullens, Breanne E. Kearney
Summary: Parent training is crucial in occupational therapy for children with sensory processing and sensory integration challenges. However, there is a lack of occupational therapy literature that addresses parents' learning needs in this context.
AMERICAN JOURNAL OF OCCUPATIONAL THERAPY
(2023)
Article
Psychology, Developmental
Chris D. May, Jennifer M. St George, Shelly Lane
Summary: The study found that a text-based program had a positive impact on fathers of children on the autism spectrum, including reducing parenting stress and increasing autism-specific parenting self-efficacy. This highly scalable intervention has the potential to influence the relationships between fathers and their children on the autism spectrum, families, and services.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2022)
Article
Family Studies
Chris D. May, Jennifer M. St George, Shelly Lane
Summary: This study explored paternal engagement in a program providing information and support to fathers raising children on the autism spectrum. The use of text-based intervention showed high rates of connection and participation, with fathers actively applying information to their parenting behavior. This cost-effective and scalable program demonstrates acceptability among fathers.
JOURNAL OF CHILD AND FAMILY STUDIES
(2021)
