Protein acetylation in metabolism — metabolites and cofactors

Nonenzymatic Protein Acetylation Detected by NAPPA Protein Arrays

(2015) Adam S. Olia et al.   ACS Chemical Biology

Site-Specific Reactivity of Nonenzymatic Lysine Acetylation

(2015) Josue Baeza et al.   ACS Chemical Biology

NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

(2015) Carles Cantó et al.   Cell Metabolism

A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

(2015) M. Mohrin et al.   SCIENCE

Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders

(2014) Morten Scheibye-Knudsen et al.   Autophagy

Inhibition of De Novo NAD + Synthesis by Oncogenic URI Causes Liver Tumorigenesis through DNA Damage

(2014) Krishna S. Tummala et al.   CANCER CELL

A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation

(2014) Gopinath Sutendra et al.   CELL

Partitioning Circadian Transcription by SIRT6 Leads to Segregated Control of Cellular Metabolism

(2014) Selma Masri et al.   CELL

Interaction of Circadian Clock Proteins CRY1 and PER2 Is Modulated by Zinc Binding and Disulfide Bond Formation

(2014) Ira Schmalen et al.   CELL

Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

(2014) Tomoyuki Mashimo et al.   CELL

Acetate Dependence of Tumors

(2014) Sarah A. Comerford et al.   CELL

Sirtuin 4 Is a Lipoamidase Regulating Pyruvate Dehydrogenase Complex Activity

(2014) Rommel A. Mathias et al.   CELL

Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle

(2014) Eija Pirinen et al.   Cell Metabolism

Akt-Dependent Metabolic Reprogramming Regulates Tumor Cell Histone Acetylation

(2014) Joyce V. Lee et al.   Cell Metabolism

SIRT7 Controls Hepatic Lipid Metabolism by Regulating the Ubiquitin-Proteasome Pathway

(2014) Tatsuya Yoshizawa et al.   Cell Metabolism

Lysine Glutarylation Is a Protein Posttranslational Modification Regulated by SIRT5

(2014) Minjia Tan et al.   Cell Metabolism

NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

(2014) Raffaele Cerutti et al.   Cell Metabolism

Linking DNA Damage, NAD + /SIRT1, and Aging

(2014) Leonard Guarente   Cell Metabolism

Evidence for a Direct Effect of the NAD+Precursor Acipimox on Muscle Mitochondrial Function in Humans

(2014) Tineke van de Weijer et al.   DIABETES

Mitochondrial protein acetylation is driven by acetyl-CoA from fatty acid oxidation

(2014) Olga Pougovkina et al.   HUMAN MOLECULAR GENETICS

Nicotinamide Phosphoribosyl Transferase/Pre-B Cell Colony-Enhancing Factor/Visfatin Is Required for Lymphocyte Development and Cellular Resistance to Genotoxic Stress

(2014) A. Rongvaux et al.   JOURNAL OF IMMUNOLOGY

Tyr Phosphorylation of PDP1 Toggles Recruitment between ACAT1 and SIRT3 to Regulate the Pyruvate Dehydrogenase Complex

(2014) Jun Fan et al.   MOLECULAR CELL

Transcriptional Repression by Histone Deacetylases in Plants

(2014) Xuncheng Liu et al.   Molecular Plant

Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae

(2014) B. T. Weinert et al.   Molecular Systems Biology

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

(2014) Daniel Kraus et al.   NATURE

Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression

(2014) Yoonjin Lee et al.   NATURE

The growing landscape of lysine acetylation links metabolism and cell signalling

(2014) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange

(2014) Mareike Lehmann et al.   NUCLEIC ACIDS RESEARCH

A QM/MM study of the catalytic mechanism of nicotinamidase

(2014) Xiang Sheng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Partial Reversal of Skeletal Muscle Aging by Restoration of Normal NAD+ Levels

(2014) Andrew R. Mendelsohn et al.   REJUVENATION RESEARCH

PCAF Improves Glucose Homeostasis by Suppressing the Gluconeogenic Activity of PGC-1α

(2014) Cheng Sun et al.   Cell Reports

Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex

(2014) Shannon N Nangle et al.   eLife

Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation

(2014) Jenny D.Y. Chow et al.   Molecular Metabolism

ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4

(2013) Jun Mori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Influence of Metabolism on Epigenetics and Disease

(2013) William G. Kaelin et al.   CELL

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

(2013) Ana P. Gomes et al.   CELL

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

(2013) Laurent Mouchiroud et al.   CELL

SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging

(2013) Hung-Chun Chang et al.   CELL

SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks

(2013) Matthew J. Rardin et al.   Cell Metabolism

Nicotinamide riboside, a trace nutrient in foods, is a Vitamin B3 with effects on energy metabolism and neuroprotection

(2013) Yuling Chi et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Sirt3 Regulates Metabolic Flexibility of Skeletal Muscle Through Reversible Enzymatic Deacetylation

(2013) E. Jing et al.   DIABETES

Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis

(2013) Partha Mukhopadhyay et al.   HEPATOLOGY

Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS

(2013) Ines Taes et al.   HUMAN MOLECULAR GENETICS

Endurance training ameliorates the metabolic and performance characteristics of circadian Clock mutant mice

(2013) Stephen Pastore et al.   JOURNAL OF APPLIED PHYSIOLOGY

Yeast Phospholipase C Is Required for Normal Acetyl-CoA Homeostasis and Global Histone Acetylation

(2013) Luciano Galdieri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuin 1-mediated Effects of Exercise and Resveratrol on Mitochondrial Biogenesis

(2013) Keir J. Menzies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Widespread and Enzyme-independentNϵ-Acetylation andNϵ-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix

(2013) Gregory R. Wagner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins

(2013) Jessica L. Feldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects

(2013) Kim Ravnskjaer et al.   JOURNAL OF CLINICAL INVESTIGATION

The sirtuin family’s role in aging and age-associated pathologies

(2013) Jessica A. Hall et al.   JOURNAL OF CLINICAL INVESTIGATION

An acetylation rheostat for the control of muscle energy homeostasis

(2013) Keir Menzies et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Nicotinamide improves glucose metabolism and affects the hepatic NAD-sirtuin pathway in a rodent model of obesity and type 2 diabetes

(2013) Soo Jin Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Yeast AMPK Homolog SNF1 Regulates Acetyl Coenzyme A Homeostasis and Histone Acetylation

(2013) M. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes

(2013) Carles Cantó et al.   MOLECULAR ASPECTS OF MEDICINE

Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth

(2013) Ruiting Lin et al.   MOLECULAR CELL

SIRT4 Coordinates the Balance between Lipid Synthesis and Catabolism by Repressing Malonyl CoA Decarboxylase

(2013) Gaëlle Laurent et al.   MOLECULAR CELL

Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli

(2013) Brian T. Weinert et al.   MOLECULAR CELL

SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways

(2013) Jeongsoon Park et al.   MOLECULAR CELL

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

(2013) Hong Jiang et al.   NATURE

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

(2013) Bing Gong et al.   NEUROBIOLOGY OF AGING

Metabolism and the Circadian Clock Converge

(2013) Kristin Eckel-Mahan et al.   PHYSIOLOGICAL REVIEWS

Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice

(2013) C. B. Peek et al.   SCIENCE

Metabolic Characterization of a Sirt5 deficient mouse model

(2013) Jiujiu Yu et al.   Scientific Reports

SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease

(2013) Jiyung Shin et al.   Cell Reports

Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

(2012) Li Qiang et al.   CELL

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

(2012) Carles Cantó et al.   Cell Metabolism

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38: Implications for Cellular NAD+ Metabolism, Protein Acetylation, and Treatment of Metabolic Syndrome

(2012) C. Escande et al.   DIABETES

Regulation of Poly(ADP-ribose) Polymerase-1-dependent Gene Expression through Promoter-directed Recruitment of a Nuclear NAD+Synthase

(2012) Tong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acetyl-CoA Carboxylase Regulates Global Histone Acetylation

(2012) Luciano Galdieri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis

(2012) John E. Dominy et al.   MOLECULAR CELL

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

(2012) Zheng Sun et al.   NATURE MEDICINE

CITED2 links hormonal signaling to PGC-1α acetylation in the regulation of gluconeogenesis

(2012) Mashito Sakai et al.   NATURE MEDICINE

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

SIRT2 Ablation Has No Effect on Tubulin Acetylation in Brain, Cholesterol Biosynthesis or the Progression of Huntington's Disease Phenotypes In Vivo

(2012) Anna Bobrowska et al.   PLoS One

Effects of Niacin Restriction on Sirtuin and PARP Responses to Photodamage in Human Skin

(2012) Claudia A. Benavente et al.   PLoS One

Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue

(2012) Hassina Massudi et al.   PLoS One

Suppression of Oxidative Stress by  -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

(2012) T. Shimazu et al.   SCIENCE

Protein N-terminal acetyltransferases: when the start matters

(2012) Kristian K. Starheim et al.   TRENDS IN BIOCHEMICAL SCIENCES

The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Metabolic reprogramming by class I and II histone deacetylases

(2012) Maria M. Mihaylova et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effects of zinc supplementation on diabetes mellitus: a systematic review and meta-analysis

(2012) R Jayawardena et al.   Diabetology & Metabolic Syndrome

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

(2012) Pablo J. Fernandez-Marcos et al.   Scientific Reports

Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis

(2011) Pablo J Fernandez-Marcos et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Zinc Deprivation Mediates Alcohol-Induced Hepatocyte IL-8 Analog Expression in Rodents via an Epigenetic Mechanism

(2011) Yantao Zhao et al.   AMERICAN JOURNAL OF PATHOLOGY

Deletion or Overexpression of Mitochondrial NAD+Carriers inSaccharomyces cerevisiaeAlters Cellular NAD and ATP Contents and Affects Mitochondrial Metabolism and the Rate of Glycolysis

(2011) Gennaro Agrimi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function

(2011) Hiroyasu Yamamoto et al.   CELL

Metabolic Regulation of Protein N-Alpha-Acetylation by Bcl-xL Promotes Cell Survival

(2011) Caroline H. Yi et al.   CELL

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

(2011) Maria M. Mihaylova et al.   CELL

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

(2011) Jun Yoshino et al.   Cell Metabolism

PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

(2011) Péter Bai et al.   Cell Metabolism

Histone Deacetylase 6 (HDAC6) Is an Essential Modifier of Glucocorticoid-Induced Hepatic Gluconeogenesis

(2011) R. Winkler et al.   DIABETES

Diet-induced Lethality Due to Deletion of theHdac3Gene in Heart and Skeletal Muscle

(2011) Zheng Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells

(2011) Andrey Nikiforov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction

(2011) William C. Hallows et al.   MOLECULAR CELL

SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome

(2011) Matthew D. Hirschey et al.   MOLECULAR CELL

Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes

(2011) Ling Cai et al.   MOLECULAR CELL

Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase

(2011) Wenqing Jiang et al.   MOLECULAR CELL

Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis

(2011) M. Pittelli et al.   MOLECULAR PHARMACOLOGY

Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

(2011) Nady Braidy et al.   PLoS One

Fasting and High-Fat Diet Alter Histone Deacetylase Expression in the Medial Hypothalamus

(2011) Hiromasa Funato et al.   PLoS One

Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling

(2011) B. Beirowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

(2011) E. Jing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

(2011) J. Du et al.   SCIENCE

Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database

(2011) George A. Khoury et al.   Scientific Reports

Kinetic Mechanism of the Rtt109−Vps75 Histone Acetyltransferase−Chaperone Complex

(2010) Brittany N. Albaugh et al.   BIOCHEMISTRY

Reversible binding of zinc in Plasmodium falciparum Sir2: Structure and activity of the apoenzyme

(2010) Subhra Prakash Chakrabarty et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

(2010) Lei Zhong et al.   CELL

Poly(ADP-Ribose) Polymerase 1 Participates in the Phase Entrainment of Circadian Clocks to Feeding

(2010) Gad Asher et al.   CELL

SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production

(2010) Tadahiro Shimazu et al.   Cell Metabolism

Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle

(2010) Carles Cantó et al.   Cell Metabolism

Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines

(2010) M. Lundh et al.   DIABETOLOGIA

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

Redundant Control of Adipogenesis by Histone Deacetylases 1 and 2

(2010) Michael Haberland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of the Aryl Hydrocarbon Receptor Target GeneTiPARPas a Mediator of Suppression of Hepatic Gluconeogenesis by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and of Nicotinamide as a Corrective Agent for This Effect

(2010) Silvia Diani-Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Nicotinamide Phosphoribosyltransferase

(2010) Maria Pittelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear-cytoplasmic localization of acetyl coenzyme a synthetase-1 in the rat brain

(2010) Prasanth S. Ariyannur et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Acetate metabolism and aging: An emerging connection

(2010) Tadahiro Shimazu et al.   MECHANISMS OF AGEING AND DEVELOPMENT

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

From the gut to the peripheral tissues: the multiple effects of butyrate

(2010) P. Guilloteau et al.   NUTRITION RESEARCH REVIEWS

The Nuclear Pore Complex and Nuclear Transport

(2010) S. R. Wente et al.   Cold Spring Harbor Perspectives in Biology

Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice

(2009) Kathryn Moynihan Ramsey et al.   AGING CELL

Calorie restriction alters mitochondrial protein acetylation

(2009) Bjoern Schwer et al.   AGING CELL

Skeletal muscle NAMPT is induced by exercise in humans

(2009) Sheila R. Costford et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle

(2009) Takashi Nakagawa et al.   CELL

FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States

(2009) Jongsook Kim Kemper et al.   Cell Metabolism

Assimilation of Endogenous Nicotinamide Riboside Is Essential for Calorie Restriction-mediated Life Span Extension inSaccharomyces cerevisiae

(2009) Shu-Ping Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA

(2009) R. Magnus N. Friis et al.   NUCLEIC ACIDS RESEARCH

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

(2009) Y. Nakahata et al.   SCIENCE

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

(2009) K. M. Ramsey et al.   SCIENCE

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

(2009) K. E. Wellen et al.   SCIENCE

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Structure and chemistry of the p300/CBP and Rtt109 histone acetyltransferases: implications for histone acetyltransferase evolution and function

(2008) Ling Wang et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

(2008) Marcella Fulco et al.   DEVELOPMENTAL CELL

Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

(2008) Sarah K Knutson et al.   EMBO JOURNAL

Tissue-specific regulation of SIRT1 by calorie restriction

(2008) D. Chen et al.   GENES & DEVELOPMENT

Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice

(2008) Rusty L. Montgomery et al.   JOURNAL OF CLINICAL INVESTIGATION

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

(2008) Yi Liu et al.   NATURE

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

(2008) Xin Liu et al.   NATURE

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1 

(2008) A. Coste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA