Article
Pathology
Elma Pasalic, Murtaza M. Tambuwala, Altijana Hromic-Jahjefendic
Summary: The human endometrium is a complex tissue that undergoes a monthly cycle of thickening and shedding without scarring or loss of function. Endometriosis is a reproductive disease where endometrium is found outside the uterus, affecting 6-10% of reproductive-age women worldwide. It causes pain, heavy bleeding, and infertility. The disease is believed to originate from viable endometrial cells that flow back into the peritoneum during retrograde menstruation. Treatment options include surgery, hormonal therapy, medication, diet and exercise, and in severe cases, hysterectomy.
PATHOLOGY RESEARCH AND PRACTICE
(2023)
Article
Public, Environmental & Occupational Health
Lena Birke, Dunja M. Baston-Buest, Jan-Steffen Kruessel, Tanja N. Fehm, Alexandra P. Bielfeld
Summary: The study aimed to evaluate whether a thyroid-stimulating hormone (TSH) level > 2.5 mu lU/ml and premenstrual spotting could serve as non-invasive markers of endometriosis. The results showed that these markers could help increase the diagnostic reliability of endometriosis.
Article
Medicine, General & Internal
Anjeza Xholli, Umberto Scovazzi, Ambrogio Pietro Londero, Giulio Evangelisti, Elena Cavalli, Maria Giulia Schiaffino, Ilaria Vacca, Francesca Oppedisano, Mattia Francesco Ferraro, Giorgio Sirito, Filippo Molinari, Angelo Cagnacci
Summary: The aim of this study was to assess the prevalence of adenomyosis in symptomatic women in relation to the angle of flexion of the uterus. The study found that an angle of uterine flexion >210 degrees is associated with a higher prevalence of adenomyosis.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Anesthesiology
Naoko Sasamoto, Amy L. Shafrir, Britani M. Wallace, Allison F. Vitonis, Cameron J. Fraer, Jenny Sadler Gallagher, Mary DePari, Marzieh Ghiasi, Marc R. Laufer, Christine B. Sieberg, Amy D. DiVasta, Andrew Schrepf, Sawsan As-Sanie, Kathryn L. Terry, Stacey A. Missmer
Summary: We analyzed the pelvic pain characteristics among adolescents and adults with and without endometriosis over a 2-year follow-up period. The participants completed questionnaires that included validated measures of pain severity, frequency, and life interference. The study found that endometriosis cases reported more severe and frequent pain compared to controls, but there was improvement in acyclic pelvic pain over time. The trends differed between cases and controls, highlighting the importance of assessing multidimensional features of pelvic pain.
Article
Anesthesiology
Thomas Andrieu, Andrea Chicca, Daniele Pellegata, Nick A. Bersinger, Sara Imboden, Konstantinos Nirgianakis, Juerg Gertsch, Michael D. Mueller
Summary: This case-control study found that levels of endocannabinoids (eCBs) are significantly influenced by both noncyclic and cyclic abdominal pain, suggesting a potential role of the eCB system in endometriosis-associated pain.
Article
Anesthesiology
Natasha L. Orr, Kate J. Wahl, Michelle Lisonek, Angela Joannou, Heather Noga, Arianne Albert, Mohamed A. Bedaiwy, Christina Williams, Catherine Allaire, Paul J. Yong
Summary: This study explored the concept of using a CSI cutoff of 40 to identify patients with endometriosis who have pain associated with central nervous system sensitization. A significant correlation was found between the number of central sensitivity syndromes (CSS) and pain scores, as well as the CSI score. A CSI cutoff of 40 demonstrated high sensitivity and specificity in identifying patients with >= 3 CSS, suggesting its potential as a practical tool in clinical settings.
Article
Biochemistry & Molecular Biology
Veronika Aleksandrovych, Anna Wrona, Tomasz Bereza, Kazimierz Pitynski, Krzysztof Gil
Summary: Tubal factor infertility can be caused by various factors, including impaired muscular contractility and ciliary beating, immunological imbalance, and chronic inflammation. Telocytes in the fallopian tubes play a crucial role in regulating physiological processes such as local innervation, sensitivity to hypoxia, and hormone balances. Their involvement in nerve conduction and integration in contractions and cilia physiology highlight their significance in fertility research.
Article
Obstetrics & Gynecology
Antonio Maiorana, Marianna Maranto, Vincenzo Restivo, Daniele Lo Gerfo, Gabriella Minneci, Antonella Mercurio, Domenico Incandela
Summary: The purpose of this study was to evaluate the efficacy and long-term safety of treatment with Dienogest in patients with endometriosis. The results showed that long-term therapy with Dienogest effectively controlled the symptoms of the disease, reduced the size of endometriomas, and had minimal side effects.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Article
Medicine, General & Internal
Harald Krentel, Lisa-Kathrin Lauterbach, Georgios Mavrogiannis, Rudy Leon De Wilde
Summary: Uterine niche is a common condition in patients with a history of cesarean section. Minimally invasive techniques are effective in diagnosing and treating uterine niche related symptoms and complications, with laparoscopic fluorescence guided niche detection being a feasible option.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Bilgehan Saglik Gokmen, Nura F. Topbas Selcuki, Alev Aydin, Pinar Yalcin Bahat, Aysu Akca
Summary: This study aimed to evaluate the effect of Dienogest treatment on the size of endometriomas and the symptoms of dysmenorrhea and dyspareunia. The results showed that Dienogest treatment significantly reduced the size of endometriomas and alleviated the symptoms of dysmenorrhea and dyspareunia, especially in young patients who desire fertility preservation.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Review
Medicine, General & Internal
Christina Anna Stratopoulou, Jacques Donnez, Marie-Madeleine Dolmans
Summary: Uterine adenomyosis is a common estrogen-dependent disease affecting reproductive-age women, with no current cure available. Conservative surgery may be an option for patients wishing to preserve fertility, but carries risks and requires highly experienced surgeons. New, more effective options are needed for managing adenomyosis and improving fertility outcomes, with promising results seen in preliminary studies with gonadotropin-releasing hormone antagonists.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Nutrition & Dietetics
Betul Sukan, Yasemin Akdevelioglu, Vahide Nur Sukan
Summary: The purpose of this study was to assess the effects of antioxidant supplementation on endometriosis-related chronic pelvic pain, dysmenorrhea, and dyspareunia. The included studies showed promising results in the use of antioxidants for pain relief, but more scientific research is needed to draw clear conclusions.
CURRENT NUTRITION REPORTS
(2022)
Review
Medicine, General & Internal
Francesco G. Martire, Emilio Piccione, Caterina Exacoustos, Errico Zupi
Summary: Endometriosis affects approximately 10% of premenopausal women worldwide, and the delay in diagnosing this chronic disease is well known. The symptoms of dysmenorrhea and chronic pelvic pain in adolescence or at a young age are often underestimated, leading to a lack of early diagnosis and appropriate management.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Environmental Sciences
Maja Kotowska, Justyna Urbaniak, Wojciech J. Falecki, Piotr Lazarewicz, Mateusz Masiak, Iwona Szymusik
Summary: The study revealed that there is still a need to improve the knowledge and awareness of endometriosis, as symptoms can significantly impact the quality of life of patients. Early diagnosis is crucial for improving treatment outcomes.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Mauricio S. Abrao, Eric Surrey, Keith Gordon, Michael C. Snabes, Hui Wang, Horia Ijacu, Hugh S. Taylor
Summary: Elagolix is effective in reducing dysmenorrhea and non-menstrual pelvic pain, as well as improving health-related quality of life in women with endometriosis across various subgroups. While there were significant differences in pain reduction in some subgroups, overall the treatment showed good efficacy.
Article
Obstetrics & Gynecology
Ernesto Bosch, Carlo Bulletti, Alan B. Copperman, Renato Fanchin, Hakan Yarali, Carlos A. Pettas, Nikolaos P. Polyzos, Daniel Shapiro, Filippo Maria Ubaldi, Juan A. Garcia Velasco, Salvatore Longobardi, Thomas D'Hooghe, Peter Humaidan, Brian M. Berger, Francisco Arredondo, Catherine Avril, Pedro Barri, Jose Bellver, Christophe Blockeel, Andrea Borini, Amber Cooper, Didier Dewailly, Rui Ferriani, Alfredo Guillen, Semra Kahraman, Joaquin Llacer, Anja Bisgaard Pinborg, Paolo Levi Setti, Buelent Urman
REPRODUCTIVE BIOMEDICINE ONLINE
(2019)
Review
Oncology
Marie-Madeleine Dolmans, Matteo Lambertini, Kirsten Tryde Macklon, Teresa Almeida Santos, Ana Ruiz-Casado, Andrea Borini, Virginie Bordes, Lucy Frith, Ellen Van Moer, Ariane Germeyer
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2019)
Editorial Material
Obstetrics & Gynecology
Andrea Borini, Giovanni Coticchio
FERTILITY AND STERILITY
(2019)
Review
Obstetrics & Gynecology
Giovanni Coticchio, Cristina Lagalla, Roger Sturmey, Francesca Pennetta, Andrea Borini
HUMAN REPRODUCTION UPDATE
(2019)
Article
Spectroscopy
Valentina Notarstefano, Giorgia Gioacchini, Hugh J. Byrne, Carlotta Zaca, Elena Sereni, Lisa Vaccari, Andrea Borini, Oliana Carnevali, Elisabetta Giorgini
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2019)
Article
Multidisciplinary Sciences
M. Muratori, N. Tarozzi, F. Carpentiero, S. Danti, F. M. Perrone, M. Cambi, A. Casini, C. Azzari, L. Boni, M. Maggi, A. Borini, E. Baldi
SCIENTIFIC REPORTS
(2019)
Meeting Abstract
Obstetrics & Gynecology
Giovanni Coticchio, Raffaella Sciajno, Giulia Fiorentino, Federica Cavalera, Giovanna Nicora, Riccardo Bellazzi, Andrea Borini, Silvia Garagna, Maurizio Zuccotti
FERTILITY AND STERILITY
(2019)
Article
Genetics & Heredity
G. Scaravelli, P. E. Levi-Setti, C. Livi, G. La Sala, F. M. Ubaldi, E. Greco, M. E. Coccia, A. Borini, A. Revelli, G. Ricci, V. Vigiliano, R. De Luca, S. Bolli, L. Rienzi
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2019)
Article
Genetics & Heredity
Nicoletta Tarozzi, Marco Nadalini, Cristina Lagalla, Giovanni Coticchio, Carlotta Zaca, Andrea Borini
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2019)
Correction
Genetics & Heredity
G. Scaravelli, P. E. Levi-Setti, C. Livi, G. La Sala, F. M. Ubaldi, E. Greco, M. E. Coccia, A. Borini, A. Revelli, G. Ricci, V. Vigiliano, R. De Luca, S. Bolli, L. Rienzi, R. Spoletini, A. Drovanti, F. Benini, M. T. Villani, L. Albricci, M. T. Varricchio, V. Basile, M. Cattoli, A. Nizzi, K. Skerk, L. Speziale, S. Fiaccavento
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2019)
Article
Medicine, General & Internal
Monica Muratori, Giulia Pellegrino, Giusi Mangone, Chiara Azzari, Francesco Lotti, Nicoletta Tarozzi, Luca Boni, Andrea Borini, Mario Maggi, Elisabetta Baldi
JOURNAL OF CLINICAL MEDICINE
(2020)
Meeting Abstract
Obstetrics & Gynecology
N. Tarozzi, G. Coticchio, M. Nadalini, C. Lagalla, A. Borini
HUMAN REPRODUCTION
(2019)
Meeting Abstract
Obstetrics & Gynecology
C. Zaca, A. Bazzocchi, G. Coticchio, M. A. Bonu, A. Borini
HUMAN REPRODUCTION
(2018)
Meeting Abstract
Obstetrics & Gynecology
F. Pennetta, R. Rizzo, G. Gioacchini, N. Tarozzi, D. Bortolotti, M. Lispi, F. Barrios, A. Borini
HUMAN REPRODUCTION
(2018)
Meeting Abstract
Obstetrics & Gynecology
G. Gioacchini, V. Notarstefano, E. Sereni, C. Zaca, E. Giorgini, L. Vaccari, O. Carnevali, A. Borini
HUMAN REPRODUCTION
(2018)