Article
Radiology, Nuclear Medicine & Medical Imaging
Konrad A. Kruk, Tobias J. Dietrich, Simon Wildermuth, Sebastian Leschka, Andreas Toepfer, Stephan Waelti, Chan-Hi Olaf Kim, Sabine Guesewell, Tim Fischer
Summary: This study evaluated the feasibility of diffusion-weighted imaging (DWI) in diagnosing osteomyelitis and bone marrow edema in the forefoot. The measurement of apparent diffusion coefficient (ADC) values allowed for differentiation between healthy and abnormal bone and provided specific cutoff values for the confirmation or exclusion of osteomyelitis.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Biochemistry & Molecular Biology
Marta Orts-Arroyo, Amadeo Ten-Esteve, Sonia Gines-Cardenas, Isabel Castro, Luis Marti-Bonmati, Jose Martinez-Lillo
Summary: The synthesized gadolinium(III) complex with high relaxivity values is considered a suitable candidate for contrast-enhanced magnetic resonance imaging, providing higher resolution and better functional images.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Stefania Montemezzi, Giuseppe Cardano, Silvia Storer, Nicolo Cardobi, Carlo Cavedon, Lucia Camera
Summary: This study demonstrates the feasibility and efficacy of using DWI in MRI-guided breast biopsies for accurate lesion targeting and device positioning. DWI can effectively detect both mass and non-mass lesions with a minimum size of 5 mm.
EUROPEAN RADIOLOGY
(2021)
Review
Nanoscience & Nanotechnology
Hana Bunzen, Daniel Jirak
Summary: This review discusses the usage of metal-organic frameworks (MOFs) and composite materials based on them as contrast agents for magnetic resonance imaging (MRI). MOFs, with their design variety and high metal ion density, have been studied as a promising class of materials for developing MRI contrast agents. The review highlights important studies and classifies the materials into three groups based on their design and structural properties.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Hana Bunzen, Daniel Jirak
Summary: This review discusses the usage of metal-organic frameworks (MOFs) and composite materials based on them as contrast agents for magnetic resonance imaging (MRI). It summarizes the progress in this field over the last five years and provides an overview of MOF-based materials for heteronuclear MRI.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jie Chen, Chunchao Xia, Ting Duan, Likun Cao, Hanyu Jiang, Xijiao Liu, Zhen Zhang, Zheng Ye, Zhenru Wu, Ronghui Gao, Yujun Shi, Bin Song
Summary: Necrosis or severe ischemia was found to be a sensitive imaging feature of MTM-HCC, with a high specificity. The combination of specific findings allowed for noninvasive prediction of this subtype with good accuracy and excellent specificity.
EUROPEAN RADIOLOGY
(2021)
Article
Clinical Neurology
Feifei Zhang, Hongsheng Xie, Song Wang, Fei Li, Qiyong Gong, Zhiyun Jia
Summary: This study found that the volume of the right orbitofrontal cortex was negatively correlated with exercise addiction. The function of the right orbitofrontal cortex played an indirect role in exercise addiction and affected it through its volume. The volume of the right orbitofrontal cortex mediated the relationship between ability motivation and exercise addiction.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Chemistry, Multidisciplinary
Rebecca R. Baker, Christopher Payne, Yichao Yu, Matin Mohseni, John J. Connell, Fangyu Lin, Ian F. Harrison, Paul Southern, Umesh S. Rudrapatna, Daniel J. Stuckey, Tammy L. Kalber, Bernard Siow, Lewis Thorne, Shonit Punwani, Derek K. Jones, Mark Emberton, Quentin A. Pankhurst, Mark F. Lythgoe
Summary: Magnetic resonance navigation is an emergent technique that allows for remote control of magnetically labeled therapies and devices using an MRI system. The MINIMA technique, a novel MRI-guided ablation technique, has the potential to avoid traditional toxicities and offers precise control over the ablation volume.
Article
Radiology, Nuclear Medicine & Medical Imaging
Qiying Tang, Xinyou Liu, Qiuli Jiang, Liuhong Zhu, Jinhui Zhang, Pu-Yeh Wu, Ying Jiang, Jianjun Zhou
Summary: This study found that lower MD value from DKI, smaller diameter, and irregular margin are useful predictive biomarkers for papillary thyroid carcinoma (PTC).
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Pietro Valerio Foti, Mario Travali, Renato Farina, Stefano Palmucci, Corrado Spatola, Luigi Raffaele, Vincenzo Salamone, Rosario Caltabiano, Giuseppe Broggi, Lidia Puzzo, Andrea Russo, Michele Reibaldi, Antonio Longo, Paolo Vigneri, Teresio Avitabile, Giovani Carlo Ettorre, Antonio Basile
Summary: Uveal melanoma is a malignant tumor originating from pigmented melanocytes, with prognosis related to histopathologic and genetic features, tumor size and location. MRI plays a key role in diagnosis and treatment planning, mainly depending on melanin content for tumor visualization. Radiologists and MRI are significant in the clinical management of uveal melanoma.
INSIGHTS INTO IMAGING
(2021)
Article
Biotechnology & Applied Microbiology
Xiaoming Wang, Shiwei Guo, Zhiqian Li, Qiang Luo, Yan Dai, Hu Zhang, Yun Ye, Qiyong Gong, Kui Luo
Summary: The concept of non-metallic MRI contrast agents has emerged to address the potential toxicity of metal-based contrast agents. Paramagnetic nitroxides are being studied for their stability and imaging mechanisms similar to metal-based agents, with the challenge of lower relaxivity and rapid in vivo metabolism. Macromolecular nitroxides contrast agents have been shown to increase stability and improve water relaxation, with the potential for expanding application in tumor, liver, kidney, and cardiovascular imaging.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Urology & Nephrology
Benjamin D. Besasie, Abhijit G. Sunnapwar, Feng Gao, Dean Troyer, Geoffrey D. Clarke, Hugh White, Peter T. Fox, Anders Dale, Allison Wheeler, Michael A. Liss
Summary: Restriction spectrum imaging-magnetic resonance imaging improves upgrading detection in active surveillance for prostate cancer, especially for predicting Gleason upgrading, by providing a noninvasive radiological biomarker.
JOURNAL OF UROLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Paul D. Griffiths, Mariasavina Severino, Deborah Jarvis, Laura Mandefield, Cecilia Parazzini, Lorenzo Pinelli, Marco Di Maurizio, Fabio Triulzi, Elisa Scola, Giorgio Conte, Giovanni Palumbo, Maurilio Genovese, Andrea Rossi, Renzo Guerrini, Andrea Righini
Summary: The study included 64 foetuses with cortical formation abnormalities (CFA) who underwent two in utero magnetic resonance (iuMR) exams, with 62% showing consistent CFA description between the two studies. In 38% of cases, there was a category change, including cases without CFA initially detected, changes in laterality/symmetry, and re-classification within the same group. Brain abnormalities other than CFA were present in around half of the cases on both first and second studies. Prognosis was predicted to have changed in 8% of cases based on the second study, with all indicating a worse prognosis.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyeon Ji Jang, Sang Hyun Choi, Se Jin Choi, Won-Mook Choi, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin
Summary: This study aimed to develop and evaluate a modified LI-RADS version 2018 for diagnosing hepatocellular carcinoma (HCC) < 1.0 cm. Significant ancillary features associated with HCC < 1.0 cm were determined and applied to the modified LI-RADS. The sensitivity of our modified LI-RADS using restricted diffusion was significantly higher than LI-RADS v2018, with similar specificity.
EUROPEAN RADIOLOGY
(2023)
Review
Medicine, General & Internal
Sho Kohyama, Yuichi Yoshii, Yoshikazu Okamoto, Takahito Nakajima
Summary: This review focuses on the technical advances in reducing metal artifacts in orthopedic surgery, including digital tomosynthesis, computed tomography, and magnetic resonance imaging. Despite the introduction of new diagnostic imaging methods and technologies, metal artifacts have not yet been completely eliminated. Further research is needed to develop algorithms and techniques for reducing metal artifacts, as well as the combination of different imaging modalities to further reduce them.
Article
Health Care Sciences & Services
Ilona Swiatkowska, Johann Henckel, Shiraz A. Sabah, Alister J. Hart
Summary: This study investigated the prevalence of self-reported neurotoxicity and cognitive defects in hip replacement patients with markedly raised blood cobalt. The results showed that the frequency of reporting symptoms was significantly higher in patients with metal-on-metal implants, but clinically significant neurotoxicity was not observed.
JOURNAL OF PATIENT SAFETY
(2022)
Correction
Orthopedics
Michael T. Hirschmann, Alister Hart, Johann Henckel, Patrick Sadoghi, Romain Seil, Caroline Mouton
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2022)
Article
Orthopedics
Kevin C. Ilo, Harry S. Hothi, John A. Skinner, Alister J. Hart
Summary: This study compared different modular metal-on-metal implants from the same manufacturer and found that modular implants had a higher incidence of adverse local tissue reaction, which may be related to the modular junctions, especially the neck-stem junction, which was more susceptible to corrosion.
Article
Orthopedics
Harry Hothi, Johann Henckel, Sean Bergiers, Anna Di Laura, Klaus Schlueter-Brust, Alister Hart
Summary: This study aims to investigate the presence of voids in commercially available custom acetabular cups. The research found that some cups indeed have structural voids, which may increase the risk of crack initiation in the cups.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2023)
Article
Orthopedics
Martina Tognini, Harry Hothi, Sean Bergiers, Edel Broomfield, Stewart Tucker, Johann Henckel, Alister Hart
Summary: Retrospective analysis of explanted magnetically controlled growing rods (MCGRs) aimed to understand their fracture mechanisms and related risk factors. Findings showed that all fractured rods were single-rod constructs and greater rod contouring angles and distances between anchoring points were significant factors contributing to the fractures. Therefore, implanting double rod constructs in patients with mature spines is preferable to avoid this complication.
JOURNAL OF PEDIATRIC ORTHOPAEDICS
(2023)
Article
Biotechnology & Applied Microbiology
Sean Bergiers, Johann Henckel, Harry Hothi, Anna Di Laura, Chris Goddard, David Raymont, Furqan Ullah, Ross Cotton, Rebecca Bryan, Alister Hart
Summary: This study aimed to identify the most common locations of wear in vivo by using CT imaging, retrieval analysis, and statistical shape modelling (SSM). The results showed that wear volume, positioning, time, gender, and size had an impact on the location of wear. Understanding the function of hip implants can inform future design and improve the safe zone for implant positioning.
BIOENGINEERING-BASEL
(2023)
Article
Orthopedics
Martin A. Belzunce, Johann Henckel, Anna Di Laura, Laura M. Horga, Alister James Hart
Summary: Physical activity and a healthy lifestyle are important for delaying sarcopenia. This study aimed to quantify the benefits of cycling on muscle health in middle-aged men. The results showed that cyclists had lower levels of intramuscular fat infiltration and larger muscle mass compared to physically inactive individuals.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Orthopedics
Sara De Angelis, Johann Henckel, Sean Bergiers, Harry Hothi, Anna Di Laura, Alister Hart
Summary: The assessment of three-dimensional bony defects is important for surgical planning of hip reconstruction. Previous methods using mirroring of the contralateral side may not be useful when diseased or replaced. Statistical Shape Models (SSMs) can aid reconstruction by deriving landmarks for patients with large acetabular defects. Our study found that SSMs can effectively reconstruct bony landmarks in patients with significant lysis, regardless of defect severity. This can assist in surgical planning and implant design for hip reconstruction.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2023)
Article
Engineering, Biomedical
Maria Moralidou, Anna Di Laura, Johann Henckel, Alister J. Hart
Summary: Three-Dimensional Computed Tomography planning can predict prosthetic femoral size in un-cemented primary Total Hip Arthroplasty. However, the relationship between Prosthetic Femoral Version and Native Femoral Version is not well understood. This study aimed to assess this relationship using 3D-CT analysis.
MEDICAL ENGINEERING & PHYSICS
(2023)
Article
Orthopedics
T. Wilton, J. A. Skinner, F. S. Haddad
Summary: Recent publications have highlighted the possibility of significant performance variations among different brands of joint replacement. The National Joint Registry has conducted a detailed analysis on larger families of knee arthroplasties, with the aim of identifying any hidden differences. Analysis of the Nexgen knee arthroplasty brand revealed particularly high revision rates for aseptic loosening of the tibia in certain posterior-stabilized combinations, leading to a recall of the Nexgen 'option' tibial component. More sophisticated signal detection methods are needed to identify such variations in outcomes between closely related implant types in order to protect patients.
BONE & JOINT JOURNAL
(2023)
Article
Critical Care Medicine
Matthew J. Wood, Talal Al-Jabri, Ahmed Zaghloul, Brent Lanting, Peter V. Giannoudis, Alister James Hart
Summary: Periprosthetic acetabular fractures are rare but potentially serious complications of total hip arthroplasty. There is a lack of literature on these fractures compared to periprosthetic femoral fractures after total hip arthroplasty. This article provides an up-to-date review of the epidemiology, risk factors, diagnostic challenges, classifications, and management strategies for periprosthetic acetabular fractures after total hip arthroplasty.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2023)
Article
Cell & Tissue Engineering
C. J. Harrison, C. Y. Plessen, G. Liegl, J. N. Rodrigues, S. A. Sabah, D. J. Beard, F. Fischer
Summary: The aim of this study was to map the OKS and HAAS items to a common scale and investigate the psychometric properties of this scale for measuring knee health. The findings showed that using the common scale provided more precise measurement compared to using OKS or HAAS alone.
BONE & JOINT RESEARCH
(2023)
Review
Medicine, General & Internal
Shiraz A. Sabah, Elizabeth A. Hedge, Lennart von Fritsch, Joshua Xu, Raja Bhaskara Rajasekaran, Thomas W. Hamilton, Alexander D. Shearman, Abtin Alvand, David J. Beard, Sally Hopewell, Andrew J. Price
Summary: This systematic review aimed to summarize the evidence for the effectiveness of revision knee arthroplasty (rKA) compared to non-operative treatment for patients with failed knee arthroplasty. The results showed that implant survivorship after rKA was high, ranging from 83.2% at 15 years to 95.5% at 1 year. However, post-operative complications were common.
SYSTEMATIC REVIEWS
(2023)
Article
Orthopedics
Angelika Ramesh, Anna Di Laura, Johann Henckel, Alister Hart
Summary: CT is commonly used for pre-operative planning and assessment of THA, but there is a need for a harmonised low-dose protocol due to the variability in existing protocols. Most protocols are incomplete and only a small percentage are optimised for both field of view and image acquisition parameters. The variability emphasizes the need for a more consistent and optimal protocol for THA planning.
EFORT OPEN REVIEWS
(2023)
Review
Orthopedics
Jonas P. P. Sina, Shiraz A. A. Sabah, Daniel Schrednitzki, Andrew J. J. Price, Thomas W. W. Hamilton, Abtin Alvand
Summary: This scoping review summarizes the types, indications, and early complication rates of static spacers used to treat prosthetic joint infection after knee replacement surgery.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
