Review
Food Science & Technology
Antonio Casas-Rodriguez, Ana M. Camean, Angeles Jos
Summary: Microcystins and cylindrospermopsin can induce toxic effects in various systems and organs, including potential endocrine disruption. However, research on their endocrine disruption activity is limited and existing results are contradictory. Further studies are needed to assess the risks and understand the dose-response relationships.
Article
Multidisciplinary Sciences
Saganuwan Alhaji Saganuwan
Summary: This study investigated the effects of piroxicam on perchloric acid-induced disruption of thyroid hormones. The results showed that piroxicam can mitigate the interference of perchloric acid on thyroid hormones, as well as modulate liver enzymes, the immune system, and renal function.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Environmental Sciences
Yongwei Guo, Wei Shi, Zhiwei Liu, Xian Sun, Jiaxue Wu, Yuping Wu
Summary: The bans on BPA have led to the use of BPA alternatives and changed the environmental contamination of BPs. However, concerns have been raised about the toxicities of the emerging BPA alternatives and their effects on endocrine disruption. This study measured the concentrations of six BPs in stranded cetaceans in the South China Sea and found that large whales had higher BPs concentrations compared to small dolphins. The study also revealed a shift in BPs profiles and the continued disruption of endocrine hormones in finless porpoises.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Anita A. Thambirajah, Michael G. Wade, Jonathan Verreault, Nicolas Buisine, Veronica A. Alves, Valerie S. Langlois, Caren C. Helbing
Summary: This critical review highlights the complexity of Endocrine Disrupting Chemicals interfering with Thyroid Hormone function through interactions with other hormonal axes, and emphasizes the lack of data generated in non-mammalian vertebrate classes. With the availability of more genomics-based resources, better identification and delineation of EDC effects, modes of action, and identification of effective biomarkers suitable for HPT disruption is possible. The effects of EDCs are likely to cascade into a plurality of complex physiological effects, beyond the few variables tested within research studies.
ENVIRONMENTAL RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Joice Karina Otenio, Karine Delgado Souza, Odair Alberton, Luiz Romulo Alberton, Karyne Garcia Tafarelo Moreno, Arquimedes Gasparotto, Rhanany Alan Calloi Palozi, Emerson Luiz Botelho Lourenco, Ezilda Jacomassi
Summary: This study evaluated the thyroid-disrupting effects of chlorpyrifos (CPF) in female rats. The results showed that short-term low-dose exposure to CPF significantly increased thyroid hormone levels and had an impact on the structure of the thyroid gland.
DRUG AND CHEMICAL TOXICOLOGY
(2022)
Review
Environmental Sciences
Ekaterina P. Timokhina, Valentin V. Yaglov, Svetlana V. Nazimova
Summary: The pesticide DDT is a common endocrine disruptor that can cause both toxic and disruptive effects on the adrenal glands, with different levels of sensitivity and damage in the various adrenal cortex zones. Low-dose disruptive exposure to DDT leads to more severe affection of adrenal function.
Article
Biochemistry & Molecular Biology
Tiago Gabriel Correia, Vanessa Aparecida Rocha Oliveira Vieira, Amanda de Moraes Narcizo, Ricardo Andrade Zampieri, Lucile Maria Floeter-Winter, Renata Guimaraes Moreira
Summary: This study found that after exposure to aluminum and manganese, female ray-finned teleost fish during the vitellogenic phase showed endocrine disruption and impaired reproductive capacity, with the presence of manganese exacerbating the accumulation of aluminum in gills.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2021)
Article
Environmental Sciences
Mohd Rehan, Ummer R. Zargar, Ishfaq A. Sheikh, Saif A. Alharthy, Majed N. Almashjary, Adel M. Abuzenadah, Mohd A. Beg
Summary: Tobacco/nicotine poses a significant threat to global public health and has harmful effects on various systems of the human body. This study found that nicotine and its metabolites can interfere with the binding of carrier proteins and hormones, leading to an imbalance in hormone transport and homeostasis in the blood circulation.
Article
Endocrinology & Metabolism
Anish D. Bagga, Brian P. Johnson, Qiang Zhang
Summary: In this study, a physiologically based kinetic (PBK) model of thyroid hormones (THs) was constructed to investigate the effects of TH binding proteins (THBPs) and endocrine-disrupting chemicals (EDCs). The model accurately describes the production, distribution, and metabolism of THs, and provides novel insights such as fast blood-tissue exchanges and the limitation of tissue influx in the presence of THBPs. Continuous exposure to THBP-binding EDCs does not alter steady-state TH levels, while intermittent exposure to TBG-binding EDCs can cause greater disruptions.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Marine & Freshwater Biology
Kenji Toyota, Haruna Watanabe, Masashi Hirano, Ryoko Abe, Hitoshi Miyakawa, You Song, Tomomi Sato, Shinichi Miyagawa, Knut Erik Tollefsen, Hiroshi Yamamoto, Norihisa Tatarazako, Taisen Iguchi
Summary: This critical review provides a comprehensive understanding of the effects of juvenile hormones (JH) on freshwater cladoceran crustaceans, specifically Daphnia species, and the endocrine-disrupting effects triggered by JH analogs (JHAs). Adverse outcome pathways (AOPs) addressing the JHA-mediated effects on cladoceran leading to male offspring production and subsequent population decline are developed. The review and AOP development aim to serve as a reference for future ecotoxicological research and regulatory processes in developing tiered testing strategies and risk assessment approaches for JHAs.
AQUATIC TOXICOLOGY
(2022)
Article
Toxicology
Ishfaq Ahmad Sheikh, Mohd Amin Beg
Summary: Human exposure to various endocrine-disrupting chemicals (EDCs) has increased significantly over the past few decades, with plasticizers and flame retardants having a major impact on thyroid function. This study found that most tested compounds showed similar binding patterns to the native ligand T4, with BDE-153 and DINCH having the highest potential for thyroid dysfunction due to their tight docking conformations and high binding energy values.
JOURNAL OF APPLIED TOXICOLOGY
(2022)
Article
Geriatrics & Gerontology
Aline S. da S. Correia, Michele L. F. Nascimento, Leticia B. B. de M. Teixeira, Silvana O. E. Silva, Mario Vaisman, Patricia F. S. Teixeira
Summary: The study showed that in older patients, for each 0.1 ng/dL increase in FT4 levels, the risks of functional decline increased by 14.1% and 7.7% for baseline and mean FT4 follow-up levels, respectively. Patients with baseline FT4 levels in the fourth and fifth quintiles had a nearly 9 times higher risk of functional decline compared to those in the first quintile. No association was found between TSH and the outcome.
EUROPEAN GERIATRIC MEDICINE
(2022)
Article
Genetics & Heredity
Michael B. Morgan, James Ross, Joseph Ellwanger, Rebecca Martin Phrommala, Hannah Youngblood, Dominic Qualley, Jacob Williams
Summary: This study aimed to identify genes associated with exposure to endocrine disruptors in cnidarians. By exposing Exaiptasia diaphana to different concentrations of chemicals, 11 genes were found to have different transcription profiles under different exposure conditions. These genes could serve as candidate biomarkers for detecting transcriptional changes in steroidogenesis, gametogenesis, sterol transport, and Hedgehog signaling in cnidarians.
FRONTIERS IN GENETICS
(2022)
Article
Chemistry, Multidisciplinary
Jiwon Choi, Gowoon Lee, Sunmi Kim, Kyungho Choi
Summary: The study suggests that DBDPE and BTBPE may disrupt sex hormone regulation in male zebrafish and H295R cells, but likely not through alteration of the steroidogenesis pathway.
APPLIED SCIENCES-BASEL
(2021)
Article
Medicine, General & Internal
Xin-Miao Lin, Miao Chen, Qiao-Ling Wang, Xiao-Min Ye, Hao-Fan Chen
Summary: The study observed the effects of Kuntai capsules and FMT on endocrine indexes and uterine artery blood circulation in patients with decreased ovarian reserve function. The results showed that Kuntai capsules had a higher total effective rate compared to FMT, promoting uterine artery blood circulation, improving menstruation, relieving symptoms, and regulating endocrine function.
WORLD JOURNAL OF CLINICAL CASES
(2021)
Article
Zoology
Katharina Ruthsatz, Mark D. Scherz, Miguel Vences
Article
Multidisciplinary Sciences
Mark R. Payne, Manja Kudahl, Georg H. Engelhard, Myron A. Peck, John K. Pinnegar
Summary: The majority of the global human population resides in coastal regions, making climate risk analysis crucial for supporting adaptation. A study on the European fisheries sector identified the most at-risk fishing fleets and coastal regions. Different countries face diverse challenges posed by climate change, thus requiring tailored climate adaptation measures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Elisabeth Yarwood, Claudia Drees, Jeremy E. Niven, Wiebke Schuett
Summary: Sex-specific differences exist in the covariances between metabolic rate, body size, and exploratory behavior, suggesting that selection may act differently on males and females to produce these trait covariances with potentially important consequences for individual fitness.
Article
Biodiversity Conservation
Esteve Boutaud, Dorothea Nolte, Ingmar Harry, Thorsten Assmann, Claudia Drees
Summary: The reintroduction of grazing to counteract insect decline leads to an increase in semi-open habitats. However, the continuous presence of many species in semi-open habitats is likely due to mass effects rather than habitat heterogeneity. Nevertheless, semi-open habitats can serve as dispersal habitats and increase landscape connectivity.
BIODIVERSITY AND CONSERVATION
(2022)
Article
Biology
Sarah Howald, Marta Moyano, Amelie Crespel, Luis L. Kuchenmuller, Louise Cominassi, Guy Claireaux, Myron A. Peck, Felix C. Mark
Summary: This study examined the effects of ocean acidification and warming on the growth and metabolic rate of European sea bass. The results showed that ocean acidification did not have a significant impact on larval growth, but warming decreased larval size. Cold-conditioned fish and F0 fish had lower metabolic rates, while warming decreased larval size. This study is important for understanding the potential effects of future climate change on fish ecosystems.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2022)
Article
Multidisciplinary Sciences
Marco F. W. Gauger, Eduardo Romero-Vivas, Myron A. Peck, Eduardo F. Balart, Javier Caraveo-Patino
Summary: Marine mammals in subtropical coastal habitats, such as bottlenose dolphins, show seasonal differences in their presence, which is influenced by factors such as sea surface temperature, moon phase, tides, and hour. The dolphins are more frequently detected at moderate temperatures and during specific moon phases, tides, and hours. These seasonal differences may be related to the rhythmic patterns of the dolphins and their feeding, socializing, resting, or nursing behaviors.
Article
Zoology
Katharina Ruthsatz, Kathrin H. Dausmann, Myron A. Peck, Julian Glos
Summary: Phenotypic plasticity allows ectotherms to cope with climate changes, but the thermal tolerance and acclimation capacity vary with life stage. In this study, the common frog was used to examine the stage-specific acclimation capacity at different acclimation temperatures. The results showed that thermal tolerance and acclimation capacity were influenced by ontogenetic stage, and the lowest acclimation capacity was observed in young larvae.
JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY
(2022)
Article
Biology
Katharina Ruthsatz, Fabian Bartels, Dominik Stuetzer, Paula C. Eterovick
Summary: This study found that parental breeding time affects the sensitivity of European common frogs to nitrate pollution at different life stages. Breeding later in spring reduces hatching size and survival rate, but also induces compensatory growth. Nitrate exposure reduces developmental rate and results in larger but older larvae that are more sensitive to warmer temperatures. However, standard metabolic rate is not affected by parental breeding time or nitrate exposure. Exposure to nitrate pollution during embryonic and larval stages influences the temperature sensitivity of juvenile frogs.
JOURNAL OF THERMAL BIOLOGY
(2022)
Article
Marine & Freshwater Biology
Franziska Bils, Nicole Aberle, Cindy J. G. van Damme, Myron A. Peck, Marta Moyano
Summary: This study investigates the role of small prey in the nutrition of larval marine fish, focusing on the contribution of protozooplankton compared to metazoan microzooplankton. The results show that metazoan microzooplankton play an important role in the diets of larval fish, and highlight the limitations of stable isotope analysis.
Article
Fisheries
Amy T. Huang, Katharina Alter, Patrick Polte, Myron A. Peck
Summary: In marine fishes, the timing of spawning and maternal effects can influence the survival of offspring. This study examined egg traits and found that intrinsic differences among females or spawning waves are unlikely to significantly contribute to the poor survival of early-season progeny. Other extrinsic factors or processes, such as seasonal match-mismatch dynamics with prey, are more likely causes of mortality.
JOURNAL OF FISH BIOLOGY
(2022)
Article
Ecology
Helena Hauss, Laura Schwabe, Myron A. Peck
Summary: In a warming world, the metabolic rates of ectotherm predators and the phenology of their prey organisms may change. Understanding how intrinsic and extrinsic factors govern predator-prey interactions is crucial for grasping how the environment regulates consumer vital rates. However, controlled experiments testing both behavioural and growth responses of fish larvae and other ectotherm organisms in different feeding regimes are rare. This study is the first to directly quantify the costs and trade-offs of optimal foraging in marine fish larvae.
JOURNAL OF ANIMAL ECOLOGY
(2023)
Article
Fisheries
Dominique Robert, Jun Shoji, Pascal Sirois, Akinori Takasuka, Ignacio A. Catalan, Arild Folkvord, Stuart A. Ludsin, Myron A. Peck, Su Sponaugle, Patricia M. Ayon, Richard D. Brodeur, Emily Y. Campbell, Evan K. D'Alessandro, John F. Dower, Louis Fortier, Alberto G. Garcia, Klaus B. Huebert, Marc Hufnagl, Shin-ichi Ito, Mikimasa Joh, Francis Juanes, Mitsuo Nyuji, Yoshioki Oozeki, Guido Plaza, Motomitsu Takahashi, Yosuke Tanaka, Naoki Tojo, Shingo Watari, Naotaka Yasue, Pierre Pepin
Summary: Early life survival is crucial for the replenishment of fish populations, and the Growth-Survival Paradigm (GSP) has provided guidance for studying controlling processes. However, analysis of mortality data from published studies showed that the GSP was only supported in 56% of cases, indicating that the growth-survival relationship is more complex than previously thought. Further research is needed to understand the drivers of variability in growth-selective survival and the endpoint of pre-recruited life.
FISH AND FISHERIES
(2023)
Article
Limnology
Anna Akimova, Myron A. Peck, Gregor Boerner, Cindy van Damme, Marta Moyano
Summary: The growth and survival of Atlantic herring larvae in the North Sea are highly dependent on feeding conditions, particularly during autumn and winter. The research findings suggest that incorporating other microplankton in the diet of young herring larvae can improve their growth performance and survival probability. With the projected warming of the North Sea, herring larvae would require increased prey biomass to sustain their growth and survival.
LIMNOLOGY AND OCEANOGRAPHY
(2023)
Article
Environmental Sciences
Katharina Ruthsatz, Anja Schwarz, Ivan Gomez-Mestre, Ruth Meyer, Marie Domscheit, Fabian Bartels, Sarah-Maria Schaeffer, Karolin Engelkes
Summary: This study used African clawed frogs to investigate the effects of polyethylene microplastic (MP) ingestion on amphibian growth, development, and metabolism across two consecutive life stages, as well as the interaction between MP ingestion and rearing temperature. The results showed that MP ingestion had sublethal effects on larval growth, development, and metabolism, and led to morphological changes in juveniles. MP was also found to accumulate in both life stages. These findings indicate that juvenile amphibians may play a role in the transfer of MP from freshwater to terrestrial environments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Biodiversity Conservation
Katharina Ruthsatz, Rafael Rico-Millan, Paula Cabral Eterovick, Ivan Gomez-Mestre, Steven Cooke
Summary: Global change is impacting biodiversity and leading to declines in amphibian populations, making it important to develop non-invasive methods for studying the physiological stress in these animals. The hormone corticosterone is a useful biomarker for assessing stress, and sampling water-borne corticosterone can provide a non-invasive collection method. This study tested the validity of water-borne corticosterone as a proxy for organismal levels of corticosterone in common frog larvae, and found that it is a valid method in pro-metamorphic larvae. However, the correlation between tissue and water-borne corticosterone was not observed in other developmental stages. The study highlights the potential of water-borne corticosterone as a non-invasive tool for studying late-stage amphibian larvae, but suggests that context and developmental stage should be considered when using this method.
CONSERVATION PHYSIOLOGY
(2023)
