Article
Chemistry, Inorganic & Nuclear
Teh Ubaidah Noh, Azila Abd. Aziz, Afzan Mahmad, Nuralina Badrol
Summary: This study explored the covalent attachment of skin sensitizer using a modified electrode and nanoparticles. The modified electrode showed good reproducibility and stability, making it suitable for routine screening of skin sensitization during early product development.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Pharmacology & Pharmacy
Patrycja Szumala, Adam Macierzanka
Summary: This review focuses on recent advancements in topical microemulsion systems related to the transport of active ingredients into the skin, including those with high molecular weight and high polarity. Permeation of therapeutic macromolecules can be increased by the correct design of the microemulsion.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Pharmacology & Pharmacy
Renata Pinho Morais, Sabrina Hochheim, Carolina C. de Oliveira, Izabel C. Riegel-Vidotti, Claudia E. B. Marino
Summary: This article reviews significant findings on silica nanoparticles (SNPs) and their interactions with the skin, including synthesis, functionalization methods, skin characteristics, permeation mechanisms, and toxicity assessments. It also discusses the research progress on the use of SNPs in therapeutic and cosmetic products.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Biochemistry & Molecular Biology
Ritamaria di Lorenzo, Antonietta Bernardi, Lucia Grumetto, Antonia Sacchi, Carmen Avagliano, Serena Coppola, Anna Fiorenza de Giovanni di Santa Severina, Cristina Bruno, Lorella Paparo, Sonia Laneri, Irene Dini
Summary: The study assessed the potential of a derivative called phenylalanine butyramide (FBA) for skin application, showing promising results in cosmetic fields.
Article
Biochemistry & Molecular Biology
Ana Correia, Ana Margarida Silva, Manuela M. Moreira, Miguel Salazar, Jaroslava Svarc-Gajic, Tanja Brezo-Borjan, Maria De la Luz Cadiz-Gurrea, Antonio Segura Carretero, Francesca Loschi, Stefano Dall'Acqua, Cristina Delerue-Matos, Francisca Rodrigues
Summary: This study validated a new cosmetic ingredient extracted from Salicornia ramosissima S J. Woods through in vitro and ex vivo assays, showing potential antioxidant and anti-aging activities.
Review
Dermatology
Xueqing Hu, Huaming He
Summary: Cosmetic skin delivery plays a crucial role in the effectiveness of cosmetics, with research focusing on theoretical knowledge, evaluation methods, and legal regulations. Future emphasis should be placed on developing novel permeation enhancement technologies.
JOURNAL OF COSMETIC DERMATOLOGY
(2021)
Article
Chemistry, Medicinal
Anna W. Sobanska, Jeremy Robertson, Elzbieta Brzezinska
Summary: In this study, various chromatographic parameters and calculated molecular descriptors were tested to generate models for predicting solutes' skin permeability coefficient log Kp. It was found that parameters such as RM(0) and S were not good predictors for skin permeability coefficient, while a computational model based on (N+O), log D, and HD showed potential with an accuracy of around 83%.
Review
Environmental Sciences
Iwona Bialas, Sandra Zelent-Kraciuk, Kamil Jurowski
Summary: The EU cosmetics legislation requires skin sensitisation assessment for all cosmetics ingredients, and the evaluation should be performed using scientifically and regulatory body-accepted methods. Previous animal and human testing methods have raised ethical and practical concerns. Alternative methods have been developed and accepted, but concerns still exist regarding the presence of strong sensitisers in cosmetics formulations and the industry's risk management practices. This review aims to provide an overview of skin sensitisation assessment methods and explore the most potent skin sensitisers used in cosmetics.
Article
Biochemistry & Molecular Biology
Abigail Garcia-Villegas, Alvaro Fernandez-Ochoa, Alejandro Rojas-Garcia, Maria Elena Alanon, David Arraez-Roman, Maria de la Luz Cadiz-Gurrea, Antonio Segura-Carretero
Summary: This study evaluates the bioactive potential of mango peel extract and demonstrates its promising use as an ingredient in cosmetic formulations.
Review
Allergy
Carola Liden, Niklas Andersson, Ian R. White
Summary: The widespread use of skin sensitizing preservatives is well-known, but their use in non-cosmetic products is less recognized. This study reviewed EU legislations and analyzed data trends to find that the use of preservatives has significantly increased, posing a risk to health. Urgent action is needed to protect public health.
CONTACT DERMATITIS
(2022)
Review
Computer Science, Information Systems
Pat Vatiwutipong, Sirawich Vachmanus, Thanapon Noraset, Suppawong Tuarob
Summary: In the past decade, dermatology has made significant advancements through the use of artificial intelligence (AI) technologies. AI has been utilized for screening, diagnosis, treatment, and prediction of treatment outcomes. While previous systematic reviews have focused on medical dermatology, the adoption of AI in cosmetic dermatology has not been comprehensively reviewed. This systematic review aims to analyze existing research and recent advancements in AI applications within the field of cosmetic dermatology.
Article
Pharmacology & Pharmacy
Pratchaya Tipduangta, Wuttipan Watcharathirawongs, Peelawas Waritdecha, Busaban Sirithunyalug, Pimporn Leelapornpisid, Wantida Chaiyana, Choon Fu Goh
Summary: The study investigates the use of cellulose acetate (CA)/polyvinylpyrrolidone K-90 (PVP) electrospun fiber mats for delivering caffeine to the skin as an under-eye mask. The mats exhibit suitable physicochemical properties, non-irritating characteristics, and effective drug release and skin permeation.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Aleksandra Ziemlewska, Magdalena Wojciak, Kamila Mroziak-Lal, Martyna Zagorska-Dziok, Tomasz Bujak, Zofia Niziol-Lukaszewska, Dariusz Szczepanek, Ireneusz Sowa
Summary: This study investigates the potential effects of mushroom extracts in cosmetics. The research found that Maitake extract has notable antioxidant properties and high levels of phenols and flavonoids. The extracts effectively scavenged free radicals and chelated iron ions. Addition of mushroom extracts in washing gels reduced skin irritation and improved skin pH and hydration.
Article
Food Science & Technology
Ana Margarida Silva, Paulo C. Costa, Cristina Delerue-Matos, Piotr Latocha, Francisca Rodrigues
Summary: This review summarizes the potential cosmetic and medical skincare applications of different bioactive compounds from Actinidia arguta by-products, highlighting their beneficial effects on skin and potential contributions to circular economy. The addition of these active compounds to cosmetic and pharmaceutical products may provide photoprotection, anti-aging, and anti-inflammatory effects, among others. The impact on valorization of food by-products and circular economy is expected to be significant.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Maria Klasson, Magnus Lindberg, Eva Sarndahl, Hakan Westberg, Ing-Liss Bryngelsson, Kedeye Tuerxun, Alexander Persson
Summary: The study compared the dose- and time-effects of cobalt on the viability and cytokine release of HaCaT cells cultured at low or high calcium conditions. Results showed that cobalt exposure triggered the production of proinflammatory cytokines and chemokines in a dose- and time-dependent manner, with more differentiated cells in high calcium conditions exhibiting a stronger response in terms of IL-6 release. This suggests that the effect of cobalt chloride on cell toxicity occurs throughout the living epidermis.
Article
Multidisciplinary Sciences
Maximilien Clabaut, Amandine Suet, Pierre-Jean Racine, Ali Tahrioui, Julien Verdon, Magalie Barreau, Olivier Maillot, Agathe Le Tirant, Madina Karsybayeva, Coralie Kremser, Gerard Redziniak, Cecile Duclairoir-Poc, Chantal Pichon, Sylvie Chevalier, Marc G. J. Feuilloley
Summary: Research shows that 17 beta-estradiol has direct effects on Lactobacillus crispatus, affecting membrane dynamics and promoting biosurfactant production and adhesion to vaginal cells. These effects are important for the physiology of the vaginal environment, contributing to lactobacillus adhesion to mucosa and protection against pathogens.
SCIENTIFIC REPORTS
(2021)
Review
Microbiology
Djouhar Souak, Magalie Barreau, Aurelie Courtois, Valerie Andre, Cecile Duclairoir Poc, Marc G. J. Feuilloley, Manon Gault
Summary: Recent studies have highlighted the important role of cutaneous microbiota in skin homeostasis, photoprotection, and reversing the negative effects of UV rays on the skin. Bacterial molecules within the microbiota have been shown to block UV rays, while oral probiotics containing living microorganisms can help restore skin health. Microbial-based active sunscreen compounds show great potential as next-generation photoprotection products.
Article
Biochemistry & Molecular Biology
Mathilde Fourniere, Gilles Bedoux, Djouhar Souak, Nathalie Bourgougnon, Marc G. J. Feuilloley, Thomas Latire
Summary: The study demonstrates that poly- and oligosaccharide fractions of Ulva sp. have notable biological activities on cutaneous bacteria, especially towards acneic and non-acneic strains of Cutibacterium acnes, supporting their potential use in dermo-cosmetic applications.
Article
Multidisciplinary Sciences
Maximilien Clabaut, Amine M. Boukerb, Amine Ben Mlouka, Amandine Suet, Ali Tahrioui, Julien Verdon, Magalie Barreau, Olivier Maillot, Agathe Le Tirant, Madina Karsybayeva, Coralie Kremser, Gerard Redziniak, Cecile Duclairoir-Poc, Chantal Pichon, Julie Hardouin, Pascal Cosette, Sylvie Chevalier, Marc G. J. Feuilloley
Summary: The study found that 17 beta -estradiol affects the membrane dynamics and adhesion phenotype of Lactobacillus crispatus strains, especially promoting aggregation potential in the vaginal strain V4. However, there was no significant effect on membrane dynamics in V4 compared to strain CIP104459.
SCIENTIFIC REPORTS
(2021)
Review
Microbiology
Amine Mohamed Boukerb, Melyssa Cambronel, Sophie Rodrigues, Ouiza Mesguida, Rikki Knowlton, Marc G. J. Feuilloley, Mohamed Zommiti, Nathalie Connil
Summary: The communication between microorganisms and their hosts, known as inter-kingdom signaling, involves eukaryotic signals such as hormones influencing bacterial physiology. Stress-related catecholamines like epinephrine and norepinephrine have been shown to affect the behaviors of various Gram-negative bacteria and some Gram-positive bacteria. Epinephrine and norepinephrine trigger a signaling cascade in E. coli and S. enterica by interacting with the QseC histidine sensor kinase protein.
FRONTIERS IN MICROBIOLOGY
(2021)
Review
Microbiology
Mounir Ferchichi, Khaled Sebei, Amine Mohamed Boukerb, Najoua Karray-Bouraoui, Sylvie Chevalier, Marc G. J. Feuilloley, Nathalie Connil, Mohamed Zommiti
Summary: Enterococci face challenges in terms of virulence determinants and antimicrobial resistance, hindering their potential use as probiotics in food. The possible transmission of virulent strains through food consumption makes them unsuitable as probiotics. Selected enterococcal strains for use in food should lack virulence genes and be susceptible to clinically relevant antibiotics.
Article
Dermatology
Joan Attia-Vigneau, Magalie Barreau, Esther Le Toquin, Marc G. J. Feuilloley, Estelle Loing, Olivier Lesouhaitier
Summary: This study found that a G2 dendrigraft of lysine dendrimer can modify the membrane fluidity and biofilm formation of C. acnes acneic strain, reduce inflammation, and improve skin desquamation. The use of soft compounds in cosmetic products to modify the abundance and diversity of C. acnes strains could be a new strategy for preventing acne outbreaks.
EXPERIMENTAL DERMATOLOGY
(2022)
Article
Microbiology
Rossella Scardaci, Francesca Bietto, Pierre-Jean Racine, Amine M. Boukerb, Olivier Lesouhaitier, Marc G. J. Feuilloley, Sara Scutera, Tiziana Musso, Nathalie Connil, Enrica Pessione
Summary: This study explores the phenotypic and interactive responses of the probiotic Enterococcus faecium NCIMB10415 to the neuroactive molecules norepinephrine (NE) and serotonin (5HT) abundant in the gut, providing insights into the crucial relationship between human gut microbiota and humans. The results demonstrate that E. faecium NCIMB10415 can sense both NE and 5HT and respond accordingly.
Editorial Material
Microbiology
Mohamed Zommiti, Sylvie Chevalier, Marc G. J. Feuilloley, Nathalie Connil
Article
Infectious Diseases
Christian Hulen, Pierre-Jean Racine, Marc Feuilloley, Abdelhakim Elomri, Nour-Eddine Lomri
Summary: The study found that Curine, Guattegaumerine, and Verapamil did not inhibit the growth of Pseudomonas aeruginosa, but increased its sensitivity to certain antibiotics. Additionally, research on the ABC transporter proteins of Pseudomonas aeruginosa revealed that MsbA may be involved in antibiotic efflux.
Article
Microbiology
Damien Tortuel, Ali Tahrioui, Audrey David, Melyssa Cambronel, Flore Nilly, Thomas Clamens, Olivier Maillot, Magalie Barreau, Marc G. J. Feuilloley, Olivier Lesouhaitier, Alain Filloux, Emeline Bouffartigues, Pierre Cornelis, Sylvie Chevalier
Summary: Filamentous bacteriophages can infect Pseudomonas aeruginosa as superinfective variants, causing a massive disruption in gene expression, including those coding for virulence factors and metabolic pathways.
MICROBIOLOGY SPECTRUM
(2022)
Article
Microbiology
Mohamed Zommiti, Mounir Ferchichi, Marc G. J. Feuilloley
Article
Biochemistry & Molecular Biology
Jacques-Aurelien Sergent, Hilarion Mathouet, Christian Hulen, Pedro Lameiras, Marc Feuilloley, Abdelhakim Elomri, Nour-Eddine Lomri
Summary: This article explores the impact of two alkaloids on the multidrug efflux pump, with curine and guattegaumerine found to be weaker inhibitors compared to verapamil. The presence of curine or guattegaumerine as competitors caused the highest efflux inhibition produced by verapamil to disappear, with curine showing the most pronounced effect. The research provides new insights into the biological effects of these alkaloids and their potential as potent P-gp inhibitors.
Article
Microbiology
Xavier Janvier, Amine M. Boukerb, Marc G. J. Feuilloley, Anne Groboillot
Summary: Staphylococcus spp. and Pseudomonas spp. are widely distributed bacteria found in association with animals and humans, with some strains specifically residing on healthy human skin. The draft genome sequence data of these commensal strains have been presented.
MICROBIOLOGY RESOURCE ANNOUNCEMENTS
(2021)
Article
Microbiology
Mohamed Zommiti, Mounir Ferchichi, Khaled Sebei, Marc G. J. Feuilloley, Nathalie Connil, Amine M. Boukerb
MICROBIOLOGY RESOURCE ANNOUNCEMENTS
(2020)