Characterization of the human kinetic adjustment factor for the health risk assessment of environmental contaminants

Assessing the impact of child/adult differences in hepatic first-pass effect on the human kinetic adjustment factor for ingested toxicants

(2012) Mathieu Valcke et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

A multi-route model of nicotine–cotinine pharmacokinetics, pharmacodynamics and brain nicotinic acetylcholine receptor binding in humans

(2012) Justin G. Teeguarden et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Assessing the impact of the duration and intensity of inhalation exposure on the magnitude of the variability of internal dose metrics in children and adults

(2011) Mathieu Valcke et al.   INHALATION TOXICOLOGY

An assessment of the impact of physico-chemical and biochemical characteristics on the human kinetic adjustment factor for systemic toxicants

(2011) M. Valcke et al.   TOXICOLOGY

A stochastic whole-body physiologically based pharmacokinetic model to assess the impact of inter-individual variability on tissue dosimetry over the human lifespan

(2010) Rémy Beaudouin et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Evaluation of the impact of the exposure route on the human kinetic adjustment factor

(2010) M. Valcke et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Chemical-Specific Adjustment Factors for Intraspecies Variability of Acetone Toxicokinetics Using a Probabilistic Approach

(2010) Anna-Karin Mörk et al.   TOXICOLOGICAL SCIENCES

An Assessment of the Interindividual Variability of Internal Dosimetry during Multi-Route Exposure to Drinking Water Contaminants

(2010) Mathieu Valcke et al.   International Journal of Environmental Research and Public Health

Issues in Using Human Variability Distributions to Estimate Low-Dose Risk

(2009) Kenny S. Crump et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The Influence of Genetic Polymorphisms on Population Variability in Six Xenobiotic-Metabolizing Enzymes

(2009) Gary Ginsberg et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Genetic Polymorphism in CYP2E1: Population Distribution of CYP2E1 Activity

(2009) Pat Neafsey et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Approaches for Assessing Risks to Sensitive Populations: Lessons Learned from Evaluating Risks in the Pediatric Population

(2009) Ronald N. Hines et al.   TOXICOLOGICAL SCIENCES

Evaluation of Human Interindividual Variation in Bioactivation of Estragole Using Physiologically Based Biokinetic Modeling

(2009) Ans Punt et al.   TOXICOLOGICAL SCIENCES

Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach

(2009) Weihsueh A. Chiu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Bisphenol A levels in blood depend on age and exposure

(2009) Hans Mielke et al.   TOXICOLOGY LETTERS