Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice

(2015) Meaghan Morris et al.   NATURE NEUROSCIENCE

Assembly and Interrogation of Alzheimer’s Disease Genetic Networks Reveal Novel Regulators of Progression

(2015) Soline Aubry et al.   PLoS One

Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression

(2014) Lawryn H. Kasper et al.   NUCLEIC ACIDS RESEARCH

Regulation of the mitogen-activated protein kinase kinase (MEK)-1 by NAD+-dependent deacetylases

(2014) F Yeung et al.   ONCOGENE

Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation

(2013) Lea Tenenholz Grinberg et al.   ACTA NEUROPATHOLOGICA

Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies

(2013) David J. Irwin et al.   AMERICAN JOURNAL OF PATHOLOGY

Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance

(2013) Casey Cook et al.   HUMAN MOLECULAR GENETICS

p300-Dependent Acetylation of Activating Transcription Factor 5 Enhances C/EBP  Transactivation of C/EBP  during 3T3-L1 Differentiation

(2013) Y. Zhao et al.   MOLECULAR AND CELLULAR BIOLOGY

Cerebral atrophy in mild cognitive impairment and Alzheimer disease: Rates and acceleration

(2013) K. K. Leung et al.   NEUROLOGY

Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

(2013) E.-M. Mandelkow et al.   Cold Spring Harbor Perspectives in Medicine

Characteristics of Tau Oligomers

(2013) Yan Ren et al.   Frontiers in Neurology

The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System

(2012) Hwan-Ching Tai et al.   AMERICAN JOURNAL OF PATHOLOGY

Degradation of tau protein by autophagy and proteasomal pathways: Figure 1

(2012) Yipeng Wang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

(2012) David J. Irwin et al.   BRAIN

Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

(2012) Cristian A. Lasagna-Reeves et al.   FASEB JOURNAL

Platform-independent and Label-free Quantitation of Proteomic Data Using MS1 Extracted Ion Chromatograms in Skyline

(2012) Birgit Schilling et al.   MOLECULAR & CELLULAR PROTEOMICS

Intact neurobehavioral development and dramatic impairments of procedural-like memory following neonatal ventral hippocampal lesion in rats

(2012) L. Lecourtier et al.   NEUROSCIENCE

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

(2012) S. A. Hawley et al.   SCIENCE

Thy1-hAPPLond/Swe+mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function

(2012) Mehrdad Faizi et al.   Brain and Behavior

AMP-Activated Protein Kinase Suppresses Endothelial Cell Inflammation Through Phosphorylation of Transcriptional Coactivator p300

(2011) Yuan Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Secondary Nucleating Sequences Affect Kinetics and Thermodynamics of Tau Aggregation

(2011) Christopher L. Moore et al.   BIOCHEMISTRY

AMP-activated protein kinase inhibits TGF-β-induced fibrogenic responses of hepatic stellate cells by targeting transcriptional coactivator p300

(2011) Joong-Yeon Lim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Reversibility of Tau-Related Cognitive Defects in a Regulatable FTD Mouse Model

(2011) Astrid Sydow et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

P301S Mutant Human Tau Transgenic Mice Manifest Early Symptoms of Human Tauopathies with Dementia and Altered Sensorimotor Gating

(2011) Hiroki Takeuchi et al.   PLoS One

The acetylation of tau inhibits its function and promotes pathological tau aggregation

(2011) Todd J. Cohen et al.   Nature Communications

CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation

(2010) Lawryn H Kasper et al.   EMBO JOURNAL

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

(2010) Qihuang Jin et al.   EMBO JOURNAL

Robust Protective Effects of a Novel Multimodal Neuroprotectant Oxopropanoyloxy Benzoic Acid (a Salicylic Acid/Pyruvate Ester) in the Postischemic Brain

(2010) S.-W. Kim et al.   MOLECULAR PHARMACOLOGY

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

(2010) Byung-Hoon Lee et al.   NATURE

Hippocampal CA1 apical neuropil atrophy in mild Alzheimer disease visualized with 7-T MRI

(2010) G. A. Kerchner et al.   NEUROLOGY

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

(2010) Sang-Won Min et al.   NEURON

Comprehensive lysine acetylomes emerging from bacteria to humans

(2010) Go-Woon Kim et al.   TRENDS IN BIOCHEMICAL SCIENCES

Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options

(2009) A. C. Ludolph et al.   EUROPEAN JOURNAL OF NEUROLOGY

AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice

(2009) Tomasz Jaworski et al.   PLoS One

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL