Article
Biochemistry & Molecular Biology
Scott E. Boebinger, Rowan O. Brothers, Sistania Bong, Bharat Sanders, Courtney McCracken, Lena H. Ting, Erin M. Buckley
Summary: The study found that combining near-infrared spectroscopy with diffuse correlated spectroscopy can accurately measure the muscle oxygen metabolism index in the medial gastrocnemius of healthy adults. However, there is substantial variability in the calibration coefficient between this index and traditional assessment methods, indicating the need for calibration before each monitoring session.
Article
Medicine, General & Internal
Martijn van Hooff, Jem Arnold, Eduard Meijer, Paul Schreuder, Marta Regis, Lin Xu, Marc Scheltinga, Hans Savelberg, Goof Schep
Summary: This study compared the diagnostic accuracy of NIRS-derived variables with ABI(Flexed) in diagnosing FLIA. The results showed that NIRS kinetic variables combined with ABI(Flexed) had a higher diagnostic accuracy, while ABI(Flexed) alone had worse test characteristics.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Pediatrics
Christina H. Wolfsberger, Nina Hoeller, Ena Suppan, Bernhard Schwaberger, Berndt Urlesberger, Britt Nakstad, Gerhard Pichler
Summary: This systematic review explores the clinical use of pFOE in term and preterm neonates and the changes in pFOE values over time. The findings suggest that pFOE measured with NIRS in combination with venous occlusion can provide valuable insight into peripheral perfusion, oxygenation, and disturbances of microcirculation in neonates with different pathological findings.
FRONTIERS IN PEDIATRICS
(2022)
Article
Neurosciences
Leena N. Shoemaker, Daniel Milej, Jigneshkumar Mistry, Keith St. Lawrence
Summary: Combining DCS and NIRS allows simultaneous monitoring of cerebral hemodynamic parameters, but signal contamination from extracerebral tissue can affect interpretation. This study aimed to evaluate extracerebral signal contamination during transient hypotension and assess means of separating scalp and brain signals.
Article
Biotechnology & Applied Microbiology
Yoo Hwan Kim, Seung-Ho Paik, Youngmin Kim, Jaechul Yoon, Yong Suk Cho, Dohern Kym, Jun Hur, Wook Chun, Beop-Min Kim, Byung-Jo Kim
Summary: This study assessed the burn extent and depth in patients with burns using a custom-built 36-channel functional near-infrared spectroscopy system. Hemodynamic tissue signals measured during fNIRS showed significant differences between different burn categories, indicating that functional near-infrared spectroscopy can help with the early judgment of burn extent and depth by reflecting differences in the oxygen saturation levels in the skin.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Optics
Detian Wang, Long Wang, Jinyu Wang, Peng Gao, Shengfu Li, Liguo Zhu, Zeren Li, Tunan Chen, Fei Li, Hua Feng
Summary: The study focuses on monitoring quantitative hemodynamic parameters such as HbT, SiO2, and BFI simultaneously using a custom hybrid diffuse optical device. The results show that both BFI and SiO2 can distinguish ischemia from normal tissue, with BFI having the best discrimination ability. The hybrid device may be more effective than the traditional NIRS device in monitoring tissue ischemia, and BFI is a promising biomarker for distinguishing and quantifying ischemia.
OPTICS COMMUNICATIONS
(2021)
Article
Biochemical Research Methods
Benjamin Rinehart, Chien-Sing Poon, Ulas Sunar
Summary: The study found that the autistic group had significantly lower blood flow and oxidative metabolism compared to the control group. Combining DCS and fNIRS can provide hemodynamic and metabolic contrasts for noninvasive assessment of autism pathological conditions.
JOURNAL OF BIOPHOTONICS
(2021)
Article
Pediatrics
Ena Pritisanac, Berndt Urlesberger, Bernhard Schwaberger, Gerhard Pichler
Summary: Limited data available currently suggest that fetal hemoglobin might affect peripheral muscle oxygen extraction but not cerebral oxygenation in preterm neonates. More studies are needed to reach a final conclusion, especially regarding the oxygenation changes driven by adult red blood cell transfusions.
FRONTIERS IN PEDIATRICS
(2021)
Article
Physiology
Norita Gildea, Adam McDermott, Joel Rocha, Donal O'Shea, Simon Green, Mikel Egana
Summary: This study compared the effects of low-volume high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on oxygen uptake and muscle deoxygenation kinetics in patients with type 2 diabetes. The results showed that both training methods improved oxygen uptake kinetics, but had no significant effect on muscle deoxygenation kinetics.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Yibo Lv, Guobiao Cen, Wanjun Li, Chuanxi Zhao, Wenjie Mai
Summary: This study explores the high-quality low bandgap triple cation Sn-Pb perovskite films and fabricates a near-infrared photodetector with enhanced photoresponse. The photodetector demonstrates applicability in a pulse oximetry system, enabling accurate assessment of heart rate and blood oxygen saturation.
SCIENCE CHINA-MATERIALS
(2023)
Article
Pediatrics
Nina Hoeller, Christina H. Wolfsberger, Daniel Pfurtscheller, Corinna Binder-Heschl, Bernhard Schwaberger, Berndt Urlesberger, Gerhard Pichler
Summary: The study found that peripheral-muscle-fractional-oxygen-extraction (pFOE) was higher than peripheral-muscle-fractional-tissue-oxygen-extraction (pFTOE), especially when oxygen extraction increased. This suggests that pFOE may have more potential for detecting impaired microcirculation.
Article
Multidisciplinary Sciences
Daniel L. D. Freitas, Ana F. S. Peres, Lidiane G. Silva, Joao V. M. Mariz, Marcos G. Santos, Rayanne S. P. Morais, Camilo L. M. Morais, Francis L. Martin, Daniel A. Pascoal, Juliana D. de A. S. Camargo, Janaina C. O. Crispim, Kassio M. G. Lima
Summary: The prevention of mother-to-child transmission programs in Brazil have seen success, as access to antiretroviral therapy during pregnancy has led to a reduction in new infections among children. By utilizing near-infrared spectroscopy, pregnant women with and without HIV infection can be quickly and accurately differentiated, offering a new perspective on investigating vertical transmission and providing a potential low-cost screening tool for fast HIV detection.
SCIENTIFIC REPORTS
(2021)
Review
Hematology
Philip Crispin, Kathryn Forwood
Summary: Red cell transfusions aim to improve oxygen delivery to tissues, but the hemoglobin threshold for clinical benefit remains uncertain. Near infrared spectroscopy may help guide transfusion decisions, but there is a lack of data to recommend widespread implementation in clinical practice.
TRANSFUSION MEDICINE REVIEWS
(2021)
Article
Clinical Neurology
Seung Yup Lee, Rowan O. Brothers, Katherine B. Turrentine, Ayesha Quadri, Eashani Sathialingam, Kyle R. Cowdrick, Scott Gillespie, Shasha Bai, Adam E. Goldman-Yassen, Clinton H. Joiner, R. Clark Brown, Erin M. Buckley
Summary: This study investigates the feasibility of using diffuse optical spectroscopy to monitor cerebral hemometabolic response in children with sickle cell disease (SCD) after receiving blood transfusion. The results show that transfusion decreases oxygen extraction fraction, cerebral blood flow, and blood volume, which can be sensitively monitored using diffuse optical spectroscopy. Therefore, diffuse optical spectroscopy may be a promising tool for real-time monitoring and goal-directed therapy to reduce stroke risk in SCD patients.
FRONTIERS IN NEUROLOGY
(2022)
Article
Multidisciplinary Sciences
Yuan-Hung Pong, Yi-Kai Chang, Ching-En Hsu, Po-Cheng Chen, Yu-Chuan Lu, Vincent F. S. Tsai, Hong-Chiang Chang, Men-Tzung Lo, Chen Lin
Summary: The study showed an inverse correlation between PPG amplitude and erection hardness, as well as other correlations, suggesting that PPG may serve as a noninvasive, convenient technique for sexual function evaluation.
SCIENTIFIC REPORTS
(2021)
Article
Hematology
Rogerio Nogueira Soares, Raylene A. Reimer, Patricia K. Doyle-Baker, Juan M. Murias
Summary: This study found that mild obesity affects the responses of arm micro- and macrovascular function, but does not impact the forearm skeletal muscle response to glucose ingestion. Obese individuals showed a significant reduction in brachial artery function after glucose ingestion, whereas no significant changes were observed in lean participants.
Review
Food Science & Technology
Thiago Silveira Alvares, Gustavo Vieira de Oliveira, Monica Volino-Souza, Carlos Adam Conte-Junior, Juan Manuel Murias
Summary: Dietary nitrate ingestion has a positive effect on muscular strength and muscular endurance, with a more significant impact observed during isometric and isotonic contractions. Dosage, frequency of ingestion, training level, muscle group, and type of contraction do not appear to significantly affect the outcomes. Further experimental research is needed to explore this topic.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Food Science & Technology
Cristina Rezende, Gustavo Vieira de Oliveira, Monica Volino-Souza, Patricia Castro, Juan Manuel Murias, Thiago Silveira Alvares
Summary: The study showed that turmeric supplementation could improve cerebral oxygenation and blood volume during dynamic handgrip exercise in older males and females. Changes in heart rate and blood pressure were not significant. The findings suggest the potential of curcumin as an intervention for improving cerebral oxygenation and blood volume in older individuals.
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2022)
Article
Physiology
Rafael de Almeida Azevedo, Daniel A. Keir, Jonas Forot, Danilo Iannetta, Guillaume Y. Millet, Juan M. Murias
Summary: This study investigates the relationship between the development of slow component of oxygen uptake and muscle fatigue, finding that they are correlated in a time- and intensity-dependent manner. The results suggest that the slow component of oxygen uptake may depend on muscle fatigue, even if the mechanisms of reduced contractile function differ among intensities.
Article
Physiology
Rafael de Almeida Azevedo, Jonas Forot, Guillaume Y. Millet, Juan M. Murias
Summary: This study investigated the relationship between pulmonary oxygen uptake and muscle oxygen uptake in females and males during cycling exercise at different intensities. The results showed a correlation between the two variables regardless of exercise intensity and sex of the participants.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Review
Sport Sciences
Daniel A. Keir, Danilo Iannetta, Felipe Mattioni Maturana, John M. Kowalchuk, Juan M. Murias
Summary: This article highlights the importance of non-invasive identification of lactate threshold and respiratory compensation point during incremental exercise through pulmonary gas exchange and ventilatory variables. It also provides practical strategies for explaining the physiological mechanisms, identifying thresholds, and addressing related issues, as well as an online tool for practice and data analysis.
Article
Nutrition & Dietetics
Y. B. Somani, R. N. Soares, J. Gosalia, J. M. Delgado, M. Flanagan, S. Basu, D. B. Kim-Shapiro, J. M. Murias, D. N. Proctor
Summary: The onset of menopause and changes to ovarian hormones often lead to endothelial dysfunction in women. A study showed that acute dietary nitrate supplementation can improve endothelial function and reduce the magnitude of endothelial dysfunction caused by ischemia-reperfusion injury in healthy, early postmenopausal women.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Nutrition & Dietetics
Rafael A. Azevedo, Delbar Jazayeri, Samuel T. Yeung, Rojan Khoshreza, Guillaume Y. Millet, Juan Murias, Saied J. Aboodarda
Summary: Experiencing pain in one leg can decrease exercise tolerance and neuromuscular fatigue development in the contralateral leg. However, the effects of nonlocal experimental pain induced by blood flow occlusion on corticospinal modulation remain unknown. This study found that 25% maximal voluntary contraction (25%IMVC) duration was the shortest during blood flow occlusion, and the decline in maximal voluntary contraction was smaller compared to cycling exercise, indicating that pain reduces exercise performance. Additionally, transcranial magnetic stimulations revealed the modulation of the nervous system in response to pain stimulation.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Physiology
Danilo Iannetta, Jenny Zhang, Juan M. Murias, Saied Jalal Aboodarda
Summary: This study evaluated the extent of peripheral and central fatigue, and corresponding perceptual attributes, at task failure following cycling within different exercise intensity domains. The findings demonstrate that the extent of peripheral fatigue is highly domain-specific, whereas the extent of central fatigue is not. Sensations such as fatigue, pain, and dyspnea demonstrated intensity domain specificity and might have contributed to reaching maximal levels of perceived effort and, thus, task failure.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Nutrition & Dietetics
Austin T. Beever, Andrea Y. Zhuang, Saied Jalal Aboodarda, Juan M. Murias, Martin J. MacInnis
Summary: Hypoxia has a negative impact on aerobic exercise, but exercise testing in hypoxic conditions has not been extensively studied. This research investigated the effects of simulated altitude on gas exchange threshold, respiratory compensation point, and maximal oxygen uptake. The findings suggest that mild simulated altitude affects maximal oxygen uptake and peak power output significantly, while gas exchange threshold and respiratory compensation point remain unchanged. Moderate altitude decreases all four variables.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Physiology
Hilkka Kontro, Craig Bertagnolli, Juan M. Murias, Martin J. MacInnis
Summary: The study found that an elevated COHb concentration intensified physiological responses to exercise at the MLSS and reduced the MLSS in trained individuals. Lower effective [Hb] due to CO inhalation decreased V?O2peak and MLSS performance, with higher aerobic fitness associated with greater impairments.
EXPERIMENTAL PHYSIOLOGY
(2022)
Article
Education, Scientific Disciplines
Serena Trang, Felipe Mattioni Maturana, Juan M. Murias, Michael R. Herbert, Daniel A. Keir
Summary: In exercise physiology, laboratory components are crucial for applying theoretical concepts to personal exercise experiences and introducing data collection and analysis. The gas exchange threshold (GET) and the respiratory compensation point (RCP) are key exercise thresholds that require proper identification. However, the processing and preparation of data have been time-consuming and challenging for students. This article presents a blended laboratory model featuring the Exercise Thresholds App, which provides immediate feedback and eliminates the need for data postprocessing, allowing students to practice threshold identification skills.
ADVANCES IN PHYSIOLOGY EDUCATION
(2023)
Article
Physiology
Rafael de Almeida Azevedo, Pablo R. Fleitas-Paniagua, Mackenzie Trpcic, Danilo Iannetta, Guillaume Y. Millet, Juan M. Murias
Summary: The aim of this study is to investigate the effects of different ramp-incremental (RI) slopes on fatigability and recovery in females and males. The results showed that gender had no significant effect on performance fatigability and recovery, and different RI slopes did not alter the level of performance fatigability at task failure.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Physiology
Pablo R. Fleitas-Paniagua, Rafael de Almeida Azevedo, Mackenzie Trpcic, Juan M. Murias, Bruce Rogers
Summary: Detrended fluctuation analysis (DFA a1), an index of heart rate variability (HRV), has been of interest as a surrogate marker for exercise intensity boundaries. This report examined the behavior of heart rate variability thresholds (HRVT) across different ramp incremental slopes. The study found that the cycling ramp slope did not have a significant effect on HRVT1 and HRVT2 in terms of heart rate (HR) or VO2.
PHYSIOLOGICAL REPORTS
(2023)
Article
Physiology
Alessandro Moura Zagatto, Vithor Hugo Fialho Lopes, Yago Medeiros Dutra, Rodrigo Araujo Bonetti de Poli, Eimear Dolan, Letizia Rasica, Juan M. Murias, Paulo Henrique Silva Marques de Azevedo
Summary: This study aimed to investigate the effects of sodium bicarbonate (NaHCO3) ingestion on constant load cycling performance and neuromuscular fatigue. The results showed that NaHCO3 ingestion did not affect performance or indicators of neuromuscular fatigue. However, participants performed better when they were informed that they were ingesting an ergogenic supplement, suggesting a placebo effect may contribute to the apparent ergogenic effect of NaHCO3.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)