Article
Physiology
Kamellia Karimpour, Rhiannon J. Brenner, Grant Z. Dong, Jayne Cleve, Stefanie Martina, Catherine Harris, Gabriel J. Graf, Benjamin J. Kistler, Andrew H. Hoang, Olivia Jackson, Virginie Papadopoulou, Frauke Tillmans
Summary: Decompression sickness (DCS) is caused by the growth of bubbles in tissues and blood due to a reduction in ambient pressure. There is a need for portable ultrasound devices with long battery lives to better assess the variability of venous gas emboli (VGE) in individuals.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Acoustics
Manuel Rivera, Edwin Lopez, Silvina Cancelos
Summary: This study presents an acoustic bubble detection technique using a single element transducer device in a resonant acoustic glass chamber. By measuring the electrical properties to reflect the changes in the elastic properties of the fluid media, the presence of bubbles can be accurately detected.
Article
Multidisciplinary Sciences
David Q. Le, Andrew H. Hoang, Arian Azarang, Rachel M. Lance, Michael Natoli, Alan Gatrell, S. Lesley Blogg, Paul A. Dayton, Frauke Tillmans, Peter Lindholm, Richard E. Moon, Virginie Papadopoulou
Summary: We developed a method to generate synthetic post-dive data using Doppler ultrasound signals to detect and evaluate venous gas emboli. By providing baseline recordings and code, researchers can reproduce our work and improve upon it. This adaptable and modifiable method aims to accelerate the development of signal processing techniques for VGE analysis.
Article
Veterinary Sciences
Alicia Velazquez-Wallraf, Antonio Fernandez, Maria Jose Caballero, Andreas Mollerlokken, Paul D. Jepson, Marisa Andrada, Yara Bernaldo de Quiros
Summary: This study aimed to validate the pathological results of cetaceans through an experimental rabbit model, showing that gross and histopathological results in the experimental animal model were very similar to stranded cetaceans with DCS, reinforcing the hypothesis that individuality plays an essential role in DCS.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Physiology
Rickard Anell, Mikael Gronkvist, Mikael Gennser, Ola Eiken
Summary: The study found that an early, single excursion from high to moderate cabin altitude can effectively reduce high-altitude decompression strain and lower the occurrence of venous gas emboli. Implementing this measure during flights may be a promising way to mitigate the risk of altitude decompression sickness in aircraft with limited cabin pressurization.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Physiology
Xuhua Yu, Jiajun Xu, Wenwu Liu, Ze Zhang, Chunyang He, Weigang Xu
Summary: The study concluded that administering exogenous surfactant through aerosolization before diving is an effective, simple, and safe method for preventing decompression sickness in rats. This method significantly reduced the morbidity and mortality of decompression sickness, prolonged survival time, and decreased bubble load.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Physiology
Ola Eiken, Antonis Elia, Frode Gottschalk, Mikael Gennser, Rickard Anell
Summary: The purpose of the study was to investigate the decompression strain during a simulated parachute mission at high altitude and compare two strategies of preoxygenation. The results showed that preoxygenation at sea level can reduce decompression strain and the risk of decompression sickness.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Physiology
Anne-Virginie Desruelle, Sebastien de Maistre, Sandrine Gaillard, Simone Richard, Catherine Tardivel, Jean-Charles Martin, Jean-Eric Blatteau, Alain Boussuges, Sarah Rives, Jean-Jacques Risso, Nicolas Vallee
Summary: A study was conducted on a strain of rats that resist to hyperbaric exposure in order to explore their cecal metabolomic signature and its physiological response to stress induced by diving. A panel of differences in cecal metabolome, including changes in biliary acid metabolism and energy pathways, were found between the resistant rats and the non-exposed rats. The study suggests that the metabolites may play a role in regulating inflammation and oxidative stress management.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Physiology
Kun Zhang, Haidong Zhang, Hongjie Yi, Guoyang Huang, Xupeng Zhao, Shichong Yu, Weigang Xu
Summary: The anticonvulsive ketone ester BD-AcAc2 was found to reduce the incidence and delay the onset of decompression sickness in rats, though not significantly reducing bubble formation. It increased blood oxygen partial pressure and exhibited anti-inflammatory and antioxidant properties, highlighting its potential as a drug candidate for DCS prevention and treatment.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Environmental Sciences
Kil-Hyung Han, Gwang-Suk Hyun, Yong-Seok Jee, Jung-Min Park
Summary: This study found that pre-hydration with 30% of the recommended daily water intake before scuba diving effectively suppressed the formation of bubbles after diving, reducing the risk of decompression sickness.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Physiology
Nicolas Vallee, Emmanuel Dugrenot, Anne-Virginie Desruelle, Simone Richard, Stephane Coupe, Celine Ramdani, Regis Guieu, Jean-Jacques Risso, Sandrine Gaillard, Francois Guerrero
Summary: By selecting and breeding DCS-resistant rats and targeting SNPs linked to the immune response, a genotype that provides strong resistance to DCS was identified. Additionally, an ideal combination of SNPs that could be used in therapeutic strategies was deduced.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Costantino Balestra, Awadhesh K. Arya, Clement Leveque, Fabio Virgili, Peter Germonpre, Kate Lambrechts, Pierre Lafere, Stephen R. Thom
Summary: This study investigated the effects of different oxygen pressures on cellular reactions and found some diverse and opposite responses. Specifically, significant elevations were observed for microparticles expressing CD41, CD66b, TMEM, and phalloidin binding, while a significant decrease was observed at 1.4 ATA. Few changes were found for CD146 and TSP.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Hematology
Alicia Veninga, Constance C. F. M. J. Baaten, Ilaria De Simone, Bibian M. E. Tullemans, Marijke J. E. Kuijpers, Johan W. M. Heemskerk, Paola E. J. van der Meijden
Summary: Platelets from healthy donors exhibit heterogeneity in response to agonists, with activation thresholds controlled by various bioactive molecules. Elevated levels of priming substances like adenosine and succinate have been associated with hypercoagulability in patients with ischaemic heart disease. An improved flow cytometry methodology was employed to analyze platelet populations following activation and priming, revealing distinct responses based on the type of agonist used. The study identified five platelet populations post-activation, each with different characteristics depending on the agonist utilized, highlighting the complex and dynamic nature of platelet activation.
THROMBOSIS AND HAEMOSTASIS
(2022)
Article
Medicine, General & Internal
Benjamin Simonnet, Romain Roffi, Henri Lehot, Jean Morin, Arnaud Druelle, Lucille Daubresse, Pierre Louge, Sebastien de Maistre, Emmanuel Gempp, Nicolas Vallee, Jean-Eric Blatteau
Summary: This retrospective study aimed to determine the best therapeutic management for spinal cord decompression sickness (scDCS) in a hyperbaric center and investigate the influence of hyperbaric treatment according to different pressure levels. The study found that high initial severity and clinical deterioration within 24 hours were associated with incomplete neurological recovery. The results suggest that well-adapted initial and complementary hyperbaric treatment can mitigate the risk of long-term sequelae.
FRONTIERS IN MEDICINE
(2023)
Article
Marine & Freshwater Biology
Andrew Hoang, David Q. Le, S. Lesley Blogg, Arian Azarang, Paul A. Dayton, Peter Lindholm, Virginie Papadopoulou
Summary: We developed an algorithm based on short-term autocorrelation to estimate the heart rate in post-dive precordial Doppler ultrasound recordings. The algorithm showed accurate results with a window size of at least two seconds. Larger window sizes improved algorithm performance, but reduced accuracy for beat-to-beat heart rate estimation. Results also demonstrated good performance of the algorithm for low-grade Doppler recordings and high-grade recordings without movement, but higher errors for high-grade recordings after movement.
UNDERSEA AND HYPERBARIC MEDICINE
(2023)
Article
Sport Sciences
Luca Paolo Ardigo, Antonio Buglione, Luca Russo, Drazen Cular, Fabio Esposito, Christian Doria, Johnny Padulo
Summary: The aim of this study was to compare the metabolic cost between marathon shoes and track spikes on a running track. The results showed that there was no significant difference in metabolic cost between the two shoe conditions at different speeds. However, there may be a potential benefit of using track spikes at higher speeds, although further research is needed to confirm this.
RESEARCH IN SPORTS MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Ester Sara Di Filippo, Franco Checcaglini, Giorgio Fano-Illic, Stefania Fulle
Summary: In order to respond to changes in the environment and carry out necessary metabolic functions, cells require a functional control center. This review identifies the mitochondrion as such a control center, where messengers like H2O2, Ca2+, and Zn2+ collaborate to activate adaptive response mechanisms. By exchanging information, these messengers generate a holistic response of the cell.
Article
Physiology
Emiliano Ce, Giuseppe Coratella, Christian Doria, Marta Borrelli, Susanna Rampichini, Eloisa Limonta, Stefano Longo, Fabio Esposito
Summary: This study proposes a novel approach based on MMG signal analysis to detect voluntary activation (VA) of the synergistic superficial heads of the quadriceps muscle. The results show that VA(MMG) can be effectively used to assess VA and provide additional information when multiple synergistic muscle heads are involved in fatiguing exercises.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Meeting Abstract
Biochemistry & Molecular Biology
Marta Borrelli, Christian Doria, Eloisa Limonta, Stefano Longo, Nicholas Toninelli, Emiliano Ce, Susanna Rampichini, Fabio Esposito
Article
Sport Sciences
Johnny Padulo, Moshe Ayalon, Fabio A. Barbieri, Roberto Di Capua, Christian Doria, Luca P. Ardigo, Antonio Dello Iacono
Summary: This study investigated the effects of gradient and speed on running variability (RV) and local dynamic stability (LDS) during uphill running. The results showed that both gradient and speed increased heart rate and perceived exertion. Additionally, gradient increased running variability and impaired local dynamic stability.
SPORTS HEALTH-A MULTIDISCIPLINARY APPROACH
(2023)
Article
Sport Sciences
Susanna Rampichini, Giuseppe Coratella, Emiliano Ce, Stefano Longo, Christian Doria, Marta Borrelli, Johnny Padulo, Sheida Shokohyar, Giovanni Michielon, Eloisa Limonta, Fabio Esposito
Summary: This study investigated the acute and chronic effects of oral splint on muscle strength-endurance performance and body flexibility. The results showed that oral splint usage improved strength-endurance performance but had no effect on body flexibility.
SPORT SCIENCES FOR HEALTH
(2022)
Editorial Material
Biochemistry & Molecular Biology
Giorgio Fano-Illic, Stefania Fulle
Article
Sport Sciences
Giuseppe Coratella, Emiliano Ce, Christian Doria, Marta Borrelli, Nicholas Toninelli, Susanna Rampichini, Eloisa Limonta, Stefano Longo, Fabio Esposito
Summary: Using the mechanomyographic (MMG) signal to detect voluntary activation (VA(MMG)), the study examined the effects of neural and mechanical factors on force output after passive stretching. The results showed that passive stretching increased dorsiflexion range but decreased joint passive stiffness, maximum voluntary contraction, VA, and VA(MMG).
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Medicine, General & Internal
Francesco Coscia, Rosa Mancinelli, Paola Virginia Gigliotti, Franco Checcaglini, Giorgio Fano-Illic
Summary: This observational study examines the effects of physical activity on fatigue perception, maximum power output, sleep, and cognitive changes in long COVID-19 subjects. The results show that active subjects have significantly reduced fatigue perception compared to sedentary ones. Additionally, both active and sedentary subjects experienced reduced strength development, poor sleep quality, and mild cognitive impairment.
Article
Biochemistry & Molecular Biology
Simona Mrakic-Sposta, Alessandra Vezzoli, Giacomo Garetto, Matteo Paganini, Enrico Camporesi, Tommaso Antonio Giacon, Cinzia Dellanoce, Jacopo Agrimi, Gerardo Bosco
Summary: This study evaluated the effects of hyperbaric oxygen therapy (HBOT) on long COVID-19 patients and found that HBOT can reduce reactive oxygen species (ROS), lipid peroxidation, DNA damage, and inflammation levels. The treatment showed particularly significant results in athletes.
Meeting Abstract
Sport Sciences
Marta Borrelli, Christian Doria, Eloisa Maria Guglielmina Limonta, Stefano Longo, Emiliano Ce, Susanna Rampichini, Fabio Esposito
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Biophysics
Giorgia Committeri, Danilo Bondi, Carlo Sestieri, Ginevra Di Matteo, Claudia Piervincenzi, Christian Doria, Roberto Ruffini, Antonello Baldassarre, Tiziana Pietrangelo, Rosamaria Sepe, Riccardo Navarra, Piero Chiacchiaretta, Antonio Ferretti, Vittore Verratti
Summary: The study investigated the effects of high-altitude hypoxia on neuropsychological and neuroimaging measures. The results showed that short-term exposure to high-altitude hypoxia up to 5,000 m did not have detrimental effects on these measures, especially in the absence of altitude sickness.
HIGH ALTITUDE MEDICINE & BIOLOGY
(2022)
Article
Environmental Sciences
Morgan Levenez, Kate Lambrechts, Simona Mrakic-Sposta, Alessandra Vezzoli, Peter Germonpre, Hadrien Pique, Fabio Virgili, Gerardo Bosco, Pierre Lafere, Costantino Balestra
Summary: This study evaluated and compared the effects of using a full-face mask and a half face mask for diving on vascular function. The results showed that nasal breathing might significantly reduce the occurrence of vascular dysfunction, possibly due to better maintenance of nitric oxide production and bioavailability, resulting in a better ability to counter oxidative stress.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
Danilo Cialoni, Andrea Brizzolari, Alessandra Barassi, Gerardo Bosco, Massimo Pieri, Valentina Lancellotti, Alessandro Marroni
Summary: This study investigated the relationship between hematological parameters and predisposition to inert gas bubble formation after a single recreational dive. The results showed that divers without bubble formation had significantly higher total white blood cell, granulocyte, and lymphocyte counts before and after diving compared to divers with bubble formation, indicating a possible association between low white blood cell counts and bubble formation.
Article
Hospitality, Leisure, Sport & Tourism
Giuseppe Coratella, Gianpaolo Tornatore, Stefano Longo, Marta Borrelli, Christian Doria, Fabio Esposito, Emiliano Ce
Summary: The present study investigated the effects of verbal instruction on the electromyographic (EMG) amplitude of back-squat prime movers. It was found that internal focus had phase-dependent effects, affecting different muscles and promoting anterior-posterior balance control.
RESEARCH QUARTERLY FOR EXERCISE AND SPORT
(2022)