Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

Distribution Profiling of Circulating MicroRNAs in Serum

(2014) Jonathan Ashby et al.   ANALYTICAL CHEMISTRY

Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis

(2014) Weiying Zhou et al.   CANCER CELL

Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth

(2014) Ubaldo E. Martinez-Outschoorn et al.   SEMINARS IN CANCER BIOLOGY

Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci

(2013) Sachie Hiratsuka et al.   Nature Communications

An efficient extraction method for quantitation of adenosine triphosphate in mammalian tissues and cells

(2012) Junji Chida et al.   ANALYTICA CHIMICA ACTA

CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells

(2012) A. Tsuyada et al.   CANCER RESEARCH

Lipid-based carriers of microRNAs and intercellular communication

(2012) Kasey C. Vickers et al.   CURRENT OPINION IN LIPIDOLOGY

De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer

(2012) Xiwei Wu et al.   Journal of Translational Medicine

Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase

(2012) Xueliang Gao et al.   MOLECULAR CELL

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNAs are exported from malignant cells in customized particles

(2012) Jaime Palma et al.   NUCLEIC ACIDS RESEARCH

Cell-to-cell miRNA transfer: From body homeostasis to therapy

(2012) Roxana S. Redis et al.   PHARMACOLOGY & THERAPEUTICS

Withaferin A Synergizes the Therapeutic Effect of Doxorubicin through ROS-Mediated Autophagy in Ovarian Cancer

(2012) Miranda Y. Fong et al.   PLoS One

The Role of MicroRNAs in Cholesterol Efflux and Hepatic Lipid Metabolism

(2011) Kathryn J. Moore et al.   Annual Review of Nutrition

Microvesicles Released from Human Renal Cancer Stem Cells Stimulate Angiogenesis and Formation of Lung Premetastatic Niche

(2011) C. Grange et al.   CANCER RESEARCH

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

(2011) Stephanos Pavlides et al.   CELL CYCLE

Two-tiered Approach Identifies a Network of Cancer and Liver Disease-related Genes Regulated by miR-122

(2011) Daniel R. Boutz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation

(2011) Sachie Hiratsuka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts

(2011) Héctor Peinado et al.   SEMINARS IN CANCER BIOLOGY

Facilitative plasma membrane transporters function during ER transit

(2010) Hitomi Takanaga et al.   FASEB JOURNAL

Predominant Enhancement of Glucose Uptake in Astrocytes versus Neurons during Activation of the Somatosensory Cortex

(2010) J. Chuquet et al.   JOURNAL OF NEUROSCIENCE

NMR Metabolomic Profiling Reveals New Roles of SUMOylation in DNA Damage Response

(2010) Kristin E. Cano et al.   JOURNAL OF PROTEOME RESEARCH

Circulating MicroRNAs: a novel class of biomarkers to diagnose and monitor human cancers

(2010) Ke Zen et al.   MEDICINAL RESEARCH REVIEWS

Robust one-day in situ hybridization protocol for detection of microRNAs in paraffin samples using LNA probes

(2010) Stine Jørgensen et al.   METHODS

Context-Dependent Bidirectional Regulation of the MutS Homolog 2 by Transforming Growth Factor   Contributes to Chemoresistance in Breast Cancer Cells

(2010) Y. Yu et al.   MOLECULAR CANCER RESEARCH

Export of microRNAs and microRNA-protective protein by mammalian cells

(2010) Kai Wang et al.   NUCLEIC ACIDS RESEARCH

Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM

(2010) Y Wang et al.   ONCOGENE

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

(2010) C. V. Clower et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

(2009) Janine T. Erler et al.   CANCER CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2

(2009) Gilles A. Spoden et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Regulation of In Situ to Invasive Breast Carcinoma Transition

(2008) Min Hu et al.   CANCER CELL

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

(2008) Douglas D. Taylor et al.   GYNECOLOGIC ONCOLOGY

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

(2008) Sachie Hiratsuka et al.   NATURE CELL BIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

(2007) Jungwoon Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY