Article
Engineering, Chemical
Shohreh Khatami, Ghobad Behzadi Pour, Sedigheh Fekri Aval, Maryam Amini
Summary: The main objective of this study was to design a large-scale cold atmospheric plasma brush (LSCAPB) that can produce a perfectly homogenous large area capable of inactivating Gram-positive and Gram-negative bacteria commonly implicated in food infections. The study demonstrated that the LSCAPB had a significant inactivation effect on bacteria, with the best results obtained at 25 kV voltage. This research indicates that LSCAPB can be one of the most efficient methods for the inactivation of different types of bacteria.
PLASMA CHEMISTRY AND PLASMA PROCESSING
(2023)
Article
Infectious Diseases
Salim Manoharadas, Mohammad Altaf, Naushad Ahmad, Abdulwahed Fahad Alrefaei, Basel F. F. Al-Rayes
Summary: The emergence of antibiotic resistance in enterococci is a global concern, and almost all enterococci show significant levels of resistance to various antibiotics. Therefore, it is crucial to develop new antibacterial agents against enterococci.
Article
Physics, Applied
Yinghui Wen, Yun Luo, Xiaoling Wei, Haibo Tan, Rui Ai, Zhujiang Xiong, Liming Ye
Summary: This study investigates the antibacterial effects of liquid discharge cold plasma (LDCP) on Enterococcus faecalis (E. faecalis) planktonic cultures and root canal biofilms. The results show that LDCP treatment has a significant antibacterial effect on both planktonic E. faecalis and biofilms, surpassing the efficacy of 0.2% chlorhexidine treatment. This work suggests the potential application of liquid discharge plasma devices in root canal treatment.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Ku Youn Baik, Hyun Jo, Se Hoon Ki, Gi-Chung Kwon, Guangsup Cho
Summary: The efficiency of simultaneous treatment of cold atmospheric pressure plasma jet (CAP) and hydrogen peroxide (H2O2) was studied for bacterial disinfection. The combination of CAP with H2O2 showed dramatic synergistic effects in killing bacteria by enhancing reactive species transportation and intracellular oxidation. The non-toxic byproducts of CAP and H2O2 make their combination a promising candidate for clinical applications.
APPLIED SCIENCES-BASEL
(2023)
Article
Pharmacology & Pharmacy
Federica Perego, Rosalia Maria Ticozzi, Adriano Troia, Mauro Prato, Donatella Taramelli, Nicoletta Basilico
Summary: The study found that dextran-shelled Oxygen-Loaded NanoDroplets (OLNDs) can promote the killing of Enterococcus faecalis (E. faecalis) by macrophages and reduce inflammatory responses, potentially providing an innovative approach to healing chronic wounds.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2022)
Article
Physics, Applied
Delin Kong, Ping Zhu, Feng He, Ruoyu Han, Bingyan Yang, Manyu Wang, Jiting Ouyang
Summary: The experimental and numerical results demonstrated that the introduction of N-2 and O-2 admixture significantly affects the length and propagation velocity of a helium atmospheric-pressure plasma jet. The changes in electron density outside the grounded electrode are related to the modifications in jet length.
JOURNAL OF APPLIED PHYSICS
(2021)
Article
Instruments & Instrumentation
Qing Hong, Xiaoqing Dong, John E. E. Jones, Liang Hong, Qingsong Yu, Hongmin Sun, Meng Chen
Summary: Excessive or persistent infection impedes chronic wound healing. Antiseptics may not target all bacteria and can be cytotoxic to granulation tissue, impairing repair. Non-thermal gas atmospheric pressure plasmas provide an ideal approach for topical wound disinfection by accessing irregular cavities and fissures and killing bacteria diffusively. A novel non-thermal plasma brush device has been developed for clinical application in disinfecting oral and wound bacteria, with in vivo studies showing improved wound healing in biofilm-infected wounds treated with Ar + N-2 plasma.
REVIEW OF SCIENTIFIC INSTRUMENTS
(2023)
Article
Chemistry, Analytical
Qidi Sun, Nora F. Y. Tam, Jie Han, Will Yung-Kang Peng, Zonglong Zhu, Jian Lin Chen
Summary: Paper-based analytical devices (PADs) have become popular for their cost-effectiveness, portability, and eco-friendly features in rapid bacteria detection and biotoxicity measurement. Through colorimetric response and smartphone recording, metabolic differences among bacteria can be detected in 10 minutes, while the toxicity difference between two chlorophenols to bacteria can be identified in 30 minutes.
Article
Microbiology
Beatriz del Rio, Esther Sanchez-Llana, Noelia Martinez, Maria Fernandez, Victor Ladero, Miguel A. Alvarez
Summary: Enterococci are a diverse group of Gram-positive, lactic acid bacteria that can be found in various environments, including fermented foods, posing a health threat and hospital-acquired infections due to antimicrobial resistance. Bacteriophages are ideal biotechnological weapons for controlling bacterial growth, but require a combination of phages with different host ranges. The isolation of Enterococcus faecalis-infecting bacteriophages from cheese samples adds to the potential arsenal for bacteriophage-based biocontrol of harmful E. faecalis populations.
FRONTIERS IN MICROBIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Helena Motaln, Nina Recek, Boris Rogelj
Summary: This review examines the potential use of cold atmospheric plasma in medicine, particularly its beneficial effects on tumor reduction in oncology. It discusses the cellular changes and impacts on main cellular processes, such as proliferation, migration, protein degradation, and various forms of cell death, especially in the oncology field of plasma medicine.
Article
Cell Biology
Yanhong Wang, Xinyu Mang, Xuran Li, Zhengyu Cai, Fei Tan
Summary: This study investigated the effect and mechanism of cold atmospheric plasma (CAP) on the proliferation and apoptosis of lung cancer and colon cancer cells. The results showed that CAP treatment inhibited tumor cell proliferation and induced apoptosis through the activation of the mitochondrial pathway.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Namkyung Kim, Seunghun Lee, Soyoung Lee, Jinjoo Kang, Young-Ae Choi, Jeongsu Park, Chul-Kyu Park, Dongwoo Khang, Sang-Hyun Kim
Summary: A cold atmospheric plasma (CAP) patch was developed for the treatment of skin diseases, especially psoriasis. The patch induces the opening of calcium channels in keratinocytes and generates ROS/RNS, improving psoriatic symptoms. It can be used as a combination therapy with existing drugs, reducing side effects.
Review
Immunology
Si-yue Zhai, Michael G. Kong, Yu-min Xia
Summary: Skin diseases can be categorized into infectious diseases, non-infectious inflammatory diseases, cancers, and wounds. The underlying causes include microbial infections, autoimmune responses, abnormal cellular proliferation or differentiation, and excessive production of inflammatory factors. Cold atmospheric plasma (CAP), as an innovative and non-invasive therapeutic approach, has shown promising efficacy in dermatology by inhibiting infections, promoting wound healing, suppressing cancer growth, and improving psoriasis or vitiligo lesions. This review summarizes recent advances in CAP therapies for various skin diseases and proposes future strategies for increasing effectiveness and expanding clinical indications.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Medicine, General & Internal
Tianhao Min, Xin Xie, Kaijie Ren, Tuanhe Sun, Haonan Wang, Chengxue Dang, Hao Zhang
Summary: This article presents a narrative review on the therapeutic effects and killing mechanism of cold atmospheric plasma (CAP) on solid tumors. The effects of CAP on tumor cells, tumor microenvironment, and the immune system are discussed, along with proposed therapeutic schemes and research directions.
FRONTIERS IN MEDICINE
(2022)
Article
Engineering, Biomedical
Aydin Guelses, Lina Dohrmann, Oral Cenk Aktas, Juliane Wagner, Salih Veziroglu, Tim Tjardts, Torge Hartig, Kim Rouven Liedtke, Joerg Wiltfang, Yahya Acil, Christian Floerke
Summary: This study aimed to investigate the decontaminating effects of cold atmospheric plasma (CAP) on contaminated collagen membranes. The results showed that increasing the CAP treatment time enhanced the inhibitory effect on E. faecalis. However, microbial conglomerates remained in the deeper layers.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Engineering, Electrical & Electronic
Xingquan Wang, Xiuyuan Lu, Wei Chen, Fengpeng Wang, Jun Huang, Lingli Liu, Mengchao Li, Kui Lin
Summary: In the driving circuit, the phase difference of signals from two channels are 180 degrees. Moreover, when the duty cycle is set at 40%, it can ensure sufficient pulse width modulation response time. In the protection circuit, when over-current occurs, an intermittent output signal is automatically sent out. Furthermore, the over-current response time can be controlled independently.
Article
Engineering, Environmental
Shunfeng Ma, Jun Huang, Cheng Zhang, Guangliang Chen, Wei Chen, Tao Shao, Tongtong Li, Xianhui Zhang, Teng Gong, Kostya Ken Ostrikov
Summary: This study addresses the challenges in engineering high-performance non-precious metal-based bifunctional catalysts for water splitting. The researchers successfully grew extra-stable nickel cobalt sulfur-selenide nanosheet catalysts and demonstrated their low overpotentials and long-term stability.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Physical
Shunfeng Ma, Xianlin Qu, Jun Huang, Cheng Zhang, Guangliang Chen, Wei Chen, Tongtong Li, Tao Shao, Kun Zheng, Jietao Tian, Chaorong Li, Kostya (Ken) Ostrikov
Summary: This study presents the rational design and synthesis of hetero-interfaced Ni-Co phosphide nanowires, which exhibit exceptional activity and stability in water electrolysis under industry-relevant current densities. The Ni5P4-Co2P/NCF catalysts show significantly lower overpotentials and faster reaction kinetics compared to commercial Pt/C catalysts.
Article
Chemistry, Multidisciplinary
Xin Liu, Wei Chen, Cheng Zhang, Tongtong Li, Jun Huang, Guangliang Chen, Tao Shao, Teng Gong, Kostya Ostrikov
Summary: This study successfully engineered grid-matched palladium-nickel sulfides on a holey surface of nickel foil to enhance the electrocatalytic activity for hydrogen evolution reaction. The synthesized Pd4S-Ni3S2/HPNF catalyst exhibited high HER activity, good stability, and competitive performance.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Chemistry, Physical
Shuting Wen, Jun Huang, Tongtong Li, Wei Chen, Guangliang Chen, Qing Zhang, Xianhui Zhang, Qinyu Qian, Kostya (Ken) Ostrikov
Summary: In this study, a hybrid nanowire-nanosheet structure made of cerium oxide and nickel-cobalt phosphide (CeO2-NiCoPx) compound was in situ engineered on Ni-Co foam (CeO2-NiCoPx/NCF) for efficient and robust water splitting. The synthesized CeO2-NiCoPx/NCF catalyst exhibited excellent catalytic activity and durability for both the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER).
APPLIED CATALYSIS B-ENVIRONMENTAL
(2022)
Article
Engineering, Environmental
Jiajun Wang, Jun Huang, Guangliang Chen, Wei Chen, Tongtong Li, Aokai Meng, Kostya (Ken) Ostrikov
Summary: Due to the large Gibbs free energy of metal telluride for hydrogen generation, tellurium (Te) based materials are rarely reported as catalysts for overall water splitting. However, through a facile hydrothermal method, stacked flower-like NiTe-NiSe nanosheets have been engineered, bringing transition metal telluride closer to application in the field of clean and renewable energy. The hollow flower-shaped catalyst assembled with nanosheets significantly increases the active surface area, resulting in low overpotentials for hydrogen and oxygen evolution processes.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Environmental
Huiyang Xiang, Wei Chen, Tongtong Li, Jun Huang, Guangliang Chen, Teng Gong, Kostya Ken Ostrikov
Summary: An efficient and stable Co-Nb bimetallic phosphide electrocatalyst for HER has been successfully engineered on a dielectric barrier discharge modified carbon cloth. The catalyst shows high electrocatalytic activity and good electrochemical stability.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Physical
Xin Liu, Jun Huang, Tongtong Li, Wei Chen, Guangliang Chen, Liting Han, Kostya (Ken) Ostrikov
Summary: In this study, a multi-phase tri-metal phosphide, SnPi@CoP-Ni5P4/NCF, was prepared and used for enhancing the efficiency of oxygen evolution reaction (OER). The material exhibited excellent electrocatalytic performance and showed good stability in alkaline medium.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)