Mutations in DCHS1 cause mitral valve prolapse

Giant cadherins Fat and Dachsous self-bend to organize properly spaced intercellular junctions

(2014) Yoshikazu Tsukasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-21 represses Pdcd4 during cardiac valvulogenesis

(2013) H. J. Kolpa et al.   DEVELOPMENT

Ataxia, Dementia, and Hypogonadotropism Caused by Disordered Ubiquitination

(2013) David H. Margolin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Developmental basis for filamin-A-associated myxomatous mitral valve disease

(2012) Kimberly Sauls et al.   CARDIOVASCULAR RESEARCH

Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling

(2012) Moumita Chaki et al.   CELL

Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart

(2012) Andy Wessels et al.   DEVELOPMENTAL BIOLOGY

KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant

(2012) Christelle Golzio et al.   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development

(2011) Y. Mao et al.   DEVELOPMENT

Surgery for asymptomatic degenerative aortic and mitral valve disease

(2011) Prashant Vaishnava et al.   Nature Reviews Cardiology

Automated and Adaptable Quantification of Cellular Alignment from Microscopic Images for Tissue Engineering Applications

(2011) Feng Xu et al.   TISSUE ENGINEERING PART C-METHODS

Expression of the familial cardiac valvular dystrophy gene, filamin-A, during heart morphogenesis

(2010) R.A. Norris et al.   DEVELOPMENTAL DYNAMICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

MutationTaster evaluates disease-causing potential of sequence alterations

(2010) Jana Marie Schwarz et al.   NATURE METHODS

Identification of deleterious mutations within three human genomes

(2009) S. Chun et al.   GENOME RESEARCH

Detection of nonneutral substitution rates on mammalian phylogenies

(2009) K. S. Pollard et al.   GENOME RESEARCH

Periostin regulates atrioventricular valve maturation

(2008) Russell A. Norris et al.   DEVELOPMENTAL BIOLOGY