Expression of homologous RND efflux pump genes is dependent upon AcrB expression: implications for efflux and virulence inhibitor design

Structure and Operation of Bacterial Tripartite Pumps

(2013) Philip Hinchliffe et al.   Annual Review of Microbiology

RND-Type Efflux Pumps in Multidrug-Resistant Clinical Isolates of Acinetobacter baumannii: Major Role for AdeABC Overexpression and AdeRS Mutations

(2013) Eun-Jeong Yoon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

RND Efflux Pumps: Structural Information Translated into Function and Inhibition Mechanisms

(2013) Paolo Ruggerone et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Genetic inactivation of acrAB or inhibition of efflux induces expression of ramA

(2013) A. J. Lawler et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Interplay between Three RND Efflux Pumps in Doxycycline-Selected Strains of Burkholderia thailandensis

(2013) Fabrice Vincent Biot et al.   PLoS One

Reduction of Cellular Stress by TolC-Dependent Efflux Pumps in Escherichia coli Indicated by BaeSR and CpxARP Activation of spy in Efflux Mutants

(2012) J. L. Rosner et al.   JOURNAL OF BACTERIOLOGY

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

(2012) T. Eicher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibiotic resistance in Neisseria gonorrhoeae: origin, evolution, and lessons learned for the future

(2011) Magnus Unemo et al.   Annals of the New York Academy of Sciences

The Multidrug Efflux Pump MdtEF Protects against Nitrosative Damage during the Anaerobic Respiration inEscherichia coli

(2011) Yiliang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of NlpE Overproduction on Multidrug Resistance in Escherichia coli

(2010) K. Nishino et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium

(2010) Tsukasa Horiyama et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A 96-well plate fluorescence assay for assessment of cellular permeability and active efflux in Salmonella enterica serovar Typhimurium and Escherichia coli

(2010) N. G. Coldham et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

RamA, a Member of the AraC/XylS Family, Influences Both Virulence and Efflux in Salmonella enterica Serovar Typhimurium

(2010) A. M. Bailey et al.   JOURNAL OF BACTERIOLOGY

Regulation and physiological function of multidrug efflux pumps in Escherichia coli and Salmonella

(2009) Kunihiko Nishino et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Periplasmic adaptor protein AcrA has a distinct role in the antibiotic resistance and virulence of Salmonella enterica serovar Typhimurium

(2009) J. M. A. Blair et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

An Excretory Function for the Escherichia coli Outer Membrane Pore TolC: Upregulation of marA and soxS Transcription and Rob Activity Due to Metabolites Accumulated in tolC Mutants

(2009) J. L. Rosner et al.   JOURNAL OF BACTERIOLOGY

The Global Consequence of Disruption of the AcrAB-TolC Efflux Pump in Salmonella enterica Includes Reduced Expression of SPI-1 and Other Attributes Required To Infect the Host

(2009) M. A. Webber et al.   JOURNAL OF BACTERIOLOGY

RamA Confers Multidrug Resistance in Salmonella enterica via Increased Expression of acrB, Which Is Inhibited by Chlorpromazine

(2008) A. M. Bailey et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Site-Directed Mutagenesis Reveals Putative Substrate Binding Residues in the Escherichia coli RND Efflux Pump AcrB

(2008) J. A. Bohnert et al.   JOURNAL OF BACTERIOLOGY

AcrS/EnvR Represses Expression of the acrAB Multidrug Efflux Genes in Escherichia coli

(2008) H. Hirakawa et al.   JOURNAL OF BACTERIOLOGY

Transcriptional activation by MarA, SoxS and Rob of twotolCpromoters using one binding site: a complex promoter configuration fortolCinEscherichia coli

(2008) Aixia Zhang et al.   MOLECULAR MICROBIOLOGY