Article
Food Science & Technology
Eloisa Sevilla, Juan P. Vico, Jose F. Delgado-Blas, Bruno Gonzalez-Zorn, Clara M. Marin, Cristina Uruen, Inmaculada Martin-Burriel, Rosa Bolea, Raul C. Mainar-Jaime
Summary: This study found that resistance to colistin was very low in pigs in 2008-2009, associated with the mcr-1 gene, and undetected in 2018; resistance to 3rd generation cephalosporins increased in 2018, mainly associated with ESBL producers. Most serotypes of Salmonella involved in antimicrobial resistance displayed a multidrug resistance pattern.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Thayat Sriyapai, Chaiwat Pulsrikarn, Kosum Chansiri, Pichapak Sriyapai
Summary: Antimicrobial resistance of Salmonella and Shigella has become a major clinical and public health problem. This study investigated the antimicrobial resistance and molecular character of clinical Shigella and Salmonella isolates, revealing that the production of ESBLs is an important mechanism for resistance to extended-spectrum cephalosporins in these bacteria.
Article
Veterinary Sciences
Babafela Awosile, Md Kaisar Rahman, Ryan B. Williams, Guy H. Loneragan
Summary: This study compares the resistance of Escherichia coli and Salmonella enterica to extended-spectrum cephalosporins (ESC) in food-producing animals from nine countries. The findings reveal variability in ESC-resistant bacteria recovery among countries, which is likely influenced by individual country policies on antimicrobial use and resistance surveillance programs.
PREVENTIVE VETERINARY MEDICINE
(2022)
Article
Infectious Diseases
Se Ra Shin, Seong Mi Noh, Woo Kyung Jung, Sook Shin, Young Kyung Park, Dong Chan Moon, Suk-Kyung Lim, Yong Ho Park, Kun Taek Park
Summary: The study conducted in South Korea between 2017 and 2019 identified various ESC-resistant bacterial isolates in companion animals, with predominant species being E. coli, Klebsiella, and others. These isolates displayed diversity in sequence types and resistance genes.
Article
Infectious Diseases
Brian D. Johnston, Paul Thuras, Stephen B. Porter, Connie Clabots, James R. Johnson
Summary: The study on 216 well-characterized ESCREC isolates showed that plazomicin had the highest activity against ESCREC, with sensitivity rates >99%, while other comparators had sensitivity rates between 96-99%. The activity against ESCREC varied significantly in relation to bacterial characteristics for most agents.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2021)
Article
Microbiology
Teresita de Jesus Bello Gonzalez, Francesca Marcato, Eduardo de Freitas Costa, Henry van den Brand, Fleur A. Hoorweg, Maaike Wolthuis-Fillerup, Bas Engel, Sabine K. Schnabel, Cornelis G. van Reenen, Michael S. M. Brouwer
Summary: The prevalence of Extended-Spectrum Cephalosporin-Resistant (ESC-R) Escherichia coli colonization in Dutch veal farms increased significantly after the arrival of calves. Individual antibiotic treatments and batch antibiotic treatments may be associated with the colonization frequency.
VETERINARY MICROBIOLOGY
(2022)
Review
Food Science & Technology
Ryan Pearce, Beate Conrady, Luca Guardabassi
Summary: The objective of this study was to assess the prevalence and types of extended-spectrum β-lactamase (ESBL)-producing bacteria in retail seafood. A literature review found that the median prevalence of ESBL-contaminated products globally was 19.4%, with significantly higher rates in Asia compared to Europe and Africa. Among the analyzed isolates, 44.8% were ESBL-positive, with CTX-M being the predominant type (93.6%).
Article
Infectious Diseases
Guillaume Miltgen, Daniel Martak, Benoit Valot, Laure Kamus, Thomas Garrigos, Guillaume Verchere, Houssein Gbaguidi-Haore, Celine Ben Cimon, Mahery Ramiandrisoa, Sandrine Picot, Anne Lignereux, Geoffrey Masson, Marie-Christine Jaffar-Bandjee, Olivier Belmonte, Eric Cardinale, Didier Hocquet, Patrick Mavingui, Xavier Bertrand
Summary: Through a study on Reunion Island, we found that despite high contamination levels in animals, they are not the main source of ESBL-Ec in humans on this densely populated, high-income island. Therefore, public health policies should primarily focus on human-to-human transmission to prevent human infections with ESBL-Ec.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2022)
Article
Biochemistry & Molecular Biology
Babafela Awosile, Jessica Eisnor, Matthew E. Saab, Luke Heider, J. T. McClure
Summary: This study aimed to determine the occurrence of antimicrobial resistance to the extended-spectrum cephalosporins in Escherichia coli isolates from retail meat products in the Maritime Provinces of Canada. It was found that selective culture significantly improved the recovery of ESC-resistant E. coli isolates from retail meat samples. The study demonstrated the presence of ESBL-and AmpC-resistance genes in retail meat products in the Maritime Provinces of Canada.
CANADIAN JOURNAL OF MICROBIOLOGY
(2021)
Article
Immunology
Ricardo Ariel Gianecini, Tomas Poklepovich, Daniel Golparian, Noelia Cuenca, Ezequiel Tuduri, Magnus Unemo, Josefina Campos, Patricia Galarza
Summary: During 2015-2018, the prevalence of azithromycin-nonsusceptible gonococcal infection significantly increased in Argentina, involving two main clades ST1580 and ST9363. These strains have mutations in 23S rRNA and different MICs for azithromycin. Identifying the geographic dissemination and characteristics of these predominant clones will guide public health policies to control the spread of azithromycin-nonsusceptible N. gonorrhoeae in Argentina.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Ashley C. Cormier, Gabhan Chalmers, Roxana Zamudio, Michael R. Mulvey, Alison E. Mather, Patrick Boerlin
Summary: This study characterized the genetic profiles of bla(CTX-M-1) plasmids circulating in E. coli from Canadian domestic animals and compared them to those recovered in animals in Europe. The results showed that a similar epidemic IncI1/ST3 plasmid found in Europe is contributing to the spread of bla(CTX-M-1) in Canada, and a conserved IncHI1/FIA(HI1)/ST2 plasmid was recovered from nearly all racetrack horse isolates. Further studies are necessary to understand the factors contributing to these plasmids' success in their respective populations.
Article
Infectious Diseases
Chris Kenyon, Jolein Laumen, Sheeba Manoharan-Basil
Summary: While new gonorrhoea treatment guidelines typically focus on resistance in Neisseria gonorrhoeae, it is important to consider resistance in commensal Neisseria species as well, as resistance patterns can be passed on to N. gonorrhoeae. This highlights the importance of evaluating the impact of gonococcal therapies on resistance in commensal Neisseria.
Article
Multidisciplinary Sciences
Jeong Yeon Kim, Yunjin Yum, Hyung Joon Joo, Hyonggin An, Young Kyung Yoon, Jong Hun Kim, Jang Wook Sohn
Summary: The study found that excessive use of antibiotics affects the prevalence of resistant organisms in the future. Therefore, controlling antibiotics with antimicrobial stewardship programs should be considered to restrict antimicrobial resistance.
SCIENTIFIC REPORTS
(2021)
Article
Infectious Diseases
Gabriele Ratti, Alessia Facchin, Angelica Stranieri, Alessia Giordano, Saverio Paltrinieri, Paola Scarpa, Deborah Maragno, Alessia Gazzonis, Martina Penati, Camilla Luzzago, Paola Dall'Ara, Stefania Lauzi
Summary: This study aimed to investigate the presence and risk factors associated with the fecal carriage of ESBL/AmpC-producing E. coli in cats. Fecal samples from pet and stray cats were screened and confirmed for the presence of ESBL/AmpC-producing E. coli. Multidrug-resistant isolates were detected, and unhealthy cats and previous antibiotic therapy were significantly associated with fecal carriage of ESBL/AmpC-producing E. coli. These findings highlight the importance of antimicrobial stewardship and surveillance programs in companion animals, including stray cats.
Article
Microbiology
Gabhan Chalmers, Julie Cobean, Ryan P. Snyder, John R. Barta, Patrick Boerlin
Summary: ESC-resistant Escherichia coli were isolated from broiler chickens raised with and without therapeutic antimicrobials in Canada over a two-year period. The resistant isolates showed similarities in characteristics and plasmid types regardless of antimicrobial use. Despite the cessation of cephalosporin use in poultry production in Canada, the prevalence of ESC-resistant E. coli remained high, indicating a need for further research on transmission and persistence.
VETERINARY MICROBIOLOGY
(2021)