Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration

Determinants of darunavir cerebrospinal fluid concentrations

(2012) Andrea Calcagno et al.   AIDS

Therapeutic Amprenavir Concentrations in Cerebrospinal Fluid

(2012) David Croteau et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics of Once-Daily Darunavir-Ritonavir and Atazanavir-Ritonavir over 72 Hours following Drug Cessation

(2011) Marta Boffito et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance

(2009) Christina M Marra et al.   AIDS

Darunavir Concentrations in Cerebrospinal Fluid and Blood in HIV-1–Infected Individuals

(2009) Aylin Yilmaz et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The transport of anti-HIV drugs across blood–CNS interfaces: Summary of current knowledge and recommendations for further research

(2009) Lavanya Varatharajan et al.   ANTIVIRAL RESEARCH

Changes in Cognition During Antiretroviral Therapy: Comparison of 2 Different Ranking Systems to Measure Antiretroviral Drug Efficacy on HIV-Associated Neurocognitive Disorders

(2009) Valerio Tozzi et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy

(2009) L. A. Cysique et al.   NEUROLOGY

Low atazanavir concentrations in cerebrospinal fluid

(2008) Brookie M Best et al.   AIDS

Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

(2008) Scott Letendre   ARCHIVES OF NEUROLOGY

Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance

(2007) Arun K. Ghosh et al.   ACCOUNTS OF CHEMICAL RESEARCH