Article
Microbiology
Ayaka Itani, Yosuke Shida, Wataru Ogasawara
Summary: Filamentous fungi grow through elongation of their apical region by exocytosis and secrete enzymes of commercial or industrial importance. The extensive branching of their hyphae makes it difficult to control hyphal growth. To truly understand the relationship between morphology and productivity, it is necessary to compare the individual hyphae's morphology and productivity. Therefore, a microfluidic system was developed to observe and investigate the relationship between their growth, morphology, and enzyme productivity.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Microbiology
Author Name Is Multiple Tagging
Summary: Filamentous fungi, such as Aspergillus fumigatus, form multicellular hyphae that are difficult to monitor quantitatively in liquid cultures. In this study, we successfully developed a method to quantitatively monitor hyphal growth in A. fumigatus by measuring optical density. This method can be used to establish a standard for hyphal quantification and to screen for novel antifungal agents against Aspergillus species.
MICROBIOLOGY SPECTRUM
(2022)
Review
Biochemistry & Molecular Biology
Weronika Slizewska, Katarzyna Struszczyk-Swita, Olga Marchut-Mikolajczyk
Summary: Halophilic filamentous fungi are able to survive in extreme environments and counteract unfavorable conditions by producing multiple secondary metabolites.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Lu Yang, Guangwei Wu, Fanyue Meng, Huomiao Ran, Wenbing Yin, Wei Li, Xiaoqing Liu
Summary: The strategies of genetic dereplication and manipulation of epigenetic regulators have been found effective in discovering natural products with novel structures in filamentous fungi. In this study, a combination of genetic dereplication and manipulation of epigenetic regulators was used to discover a novel compound, pestaloficiol X, and other known compounds in the plant endophytic fungus Pestalotiopsis fici. The study also proposed a possible biosynthesis pathway for pestaloficiol X based on comparative analysis of homologous biosynthetic gene clusters. Additionally, the study explored the effects of the mutants on conidial development and response to oxidative stressors.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Victor Hugo Rodriguez-Morelos, Maryline Calonne-Salmon, Vincent Bremhorst, Monica Garces-Ruiz, Stephane Declerck
Summary: This study found that different fungicides have varying impacts on the hyphal healing mechanism of arbuscular mycorrhizal fungi at different concentrations. Azoxystrobin was detrimental to both fungi, while fenpropimorph affected only one species. Flutolanil and pencycuron did not have any impact on the fungi. Further investigation is needed to understand the specific mechanisms involved in these effects in order to manage fungicides effectively while protecting beneficial fungi.
FRONTIERS IN PLANT SCIENCE
(2021)
Review
Microbiology
Estelle Menu, Quentin Filori, Jean-Charles Dufour, Stephane Ranque, Coralie L'Ollivier
Summary: Humans are frequently exposed to filamentous fungi, which are widespread in the environment. Under certain risk factors, these non-dermatophyte fungi can become opportunistic pathogens and cause various types of infections. The use of molecular tools and taxonomic revisions has led to the identification of an increasing number of fungi in humans. This review aims to inventory these filamentous fungi and provide details on their anatomical locations and the symptoms of infections.
Review
Biotechnology & Applied Microbiology
Antoni Gandia, Jeroen G. van den Brandhof, Freek V. W. Appels, Mitchell P. Jones
Summary: Fungi are a revolutionary and sustainable manufacturing platform that can convert byproducts and waste into flexible fungal materials, which have a wide range of applications and contribute to improving global environmental sustainability.
TRENDS IN BIOTECHNOLOGY
(2021)
Article
Plant Sciences
Edward Umberto Serghi, Vasilis Kokkoris, Calvin Cornell, Jeremy Dettman, Franck Stefani, Nicolas Corradi
Summary: The research findings show clear differences in key life history traits between dikaryotic and homokaryotic Arbuscular mycorrhizal fungi (AMF), such as germination rates and complexity of hyphal networks. This insight may have implications for the functioning of mycorrhizal symbiosis.
FRONTIERS IN PLANT SCIENCE
(2021)
Review
Biotechnology & Applied Microbiology
Audrey Masi, Robert L. Mach, Astrid R. Mach-Aigner
Summary: The pentose phosphate pathway (PPP) is a key pathway in metabolic engineering, providing NADPH and playing a role in the production of various compounds in fungi. Understanding the regulatory mechanisms of PPP can lead to targeted engineering and improved performance in industrial fungal strains.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Microbiology
Andrew S. Urquhart, Donald M. Gardiner
Summary: Fungal spore killers are genetic elements that promote their own inheritance by killing non-inheriting gametes. However, little is known about how they kill other spores within the fungal ascus. In this study, we investigate the spore killer protein SPOK1 in Podospora anserina and demonstrate that it kills by targeting DNA. This finding provides insights into the mechanisms of spore killers and their potential applications.
Article
Agronomy
Katariina Manni, Sari Ramo, Marcia Franco, Marketta Rinne, Arto Huuskonen
Summary: The occurrence of mycotoxins in forage, particularly in grass silages, can heavily impact the amount of toxins consumed by cattle. A study conducted in Finland found mycotoxins in 92% of the grass silage and whole-crop cereal silage samples, with beauvericin and roquefortine C being the most common mycotoxins. The survey results suggest that silage-fed ruminants can be exposed to a wide range of mycotoxins, and the presence of visible molds does not guarantee mycotoxin-free feed.
Article
Biotechnology & Applied Microbiology
Sebastian Tesche, Rainer Krull
Summary: The cell morphology of Actinomadura namibiensis was studied using image analysis, revealing morphological differences between salt-enhanced cultivation and standard medium. The focus was on analyzing the dispersed mycelial network, with HNS decreasing by 20% during salt-enhanced cultivation. The study also found strong correlations between macromorphological pellet shape descriptors and individual micromorphological parameters.
BIOCHEMICAL ENGINEERING JOURNAL
(2021)
Article
Microbiology
Jan Viglas, Petra Olejnikova
Summary: The ABC transporter superfamily plays a crucial role in transporting various molecules across biological membranes, including antifungal compounds in filamentous fungi. Understanding the physiological substrates and roles of individual subfamilies of ABC transporters in fungi is important for clarifying their significance in clinical and agricultural settings.
MICROBIOLOGICAL RESEARCH
(2021)
Article
Medicine, General & Internal
Jeanne Marie Queiroz Borges Bersano, Matheus Gobbo Cordeiro, Fernando Augusto Lima Marson
Summary: This study investigated the incidence and clinical characteristics of onychomycosis in patients on hemodialysis. The results showed that male sex, older age, and the presence of obesity were the main risk factors associated with onychomycosis.
FRONTIERS IN MEDICINE
(2023)
Review
Agricultural Engineering
Rachma Wikandari, Nurul Hasniah, Mohammad J. Taherzadeh
Summary: This paper discusses the application of filamentous fungi in the food industry and explores the sustainability and prospects of using these fungi for resource conversion.
BIORESOURCE TECHNOLOGY
(2022)