Biosynthesis of rapamycin and its regulation: past achievements and recent progress

Rapamycin prevents the onset of insulin-dependent diabetes mellitus (IDDM) in NOD mice

(2010) W. L. BAEDER et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Generation of high-yield rapamycin-producing strains through protoplasts-related techniques

(2009) Xiyang Chen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Dissecting the role of mTOR: Lessons from mTOR inhibitors

(2009) Ryan J.O. Dowling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Targeted inhibition of mammalian target of rapamycin for the treatment of advanced renal cell carcinoma

(2009) Anil Kapoor et al.   CANCER

Targeted Inhibition of Mammalian Target of Rapamycin Signaling Inhibits Tumorigenesis of Colorectal Cancer

(2009) P. Gulhati et al.   CLINICAL CANCER RESEARCH

Enhanced FK506 production in Streptomyces clavuligerus CKD1119 by engineering the supply of methylmalonyl-CoA precursor

(2009) SangJoon Mo et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Recent advances in the chemistry, biosynthesis and pharmacology of rapamycin analogs

(2009) Edmund I. Graziani   NATURAL PRODUCT REPORTS

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss

(2009) Luke S Tain et al.   NATURE NEUROSCIENCE

Mammalian target of rapamycin as a therapeutic target in oncology

(2008) Robert T Abraham et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Biosynthesis of polyketide synthase extender units

(2008) Yolande A. Chan et al.   NATURAL PRODUCT REPORTS