期刊
JOURNAL OF ANTIBIOTICS
卷 62, 期 4, 页码 201-205出版社
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2009.15
关键词
antibacterial activity; cyclic hexadepsipeptide; NW-G01; Streptomyces alboflavus 313
资金
- Science and Technology Ministry of China [2003CB114404]
NW-G01, a novel cyclic hexadepsipeptide antibiotic, was isolated by macroporous resin and silica gel column chromatography and HPLC from the fermentation broth of strain no. 313. The producing strain was identified as Streptomyces alboflavus on the basis of the morphological characteristics, physiological property and 16S rDNA gene sequence analysis. NW-G01 exhibited strong antibacterial activity against Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, methicillin-resistant S. aureus, and their MIC values were 3.90, 3.90, 7.81 and 7.81 mu g ml(-1), respectively. The Journal of Antibiotics (2009) 62, 201-205; doi:10.1038/ja.2009.15; published online 6 March 2009
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