Article
Biotechnology & Applied Microbiology
Ke Li, Ming Yang, Li Jia, Mengyue Tian, Jinliang Du, Yinghao Wu, Lining Yuan, Lianmin Li, Yuzhong Ma
Summary: In this study, the preventive effect of Lactobacillus plantarum 17-5 on Escherichia coli-induced mastitis in mice was evaluated. The results showed that L. plantarum 17-5 maintained the integrity of tight junctions, improved inflammatory injury, decreased MPO activity and the mRNA expression levels of IL1 beta, IL6, and TNF alpha, and inhibited the NF-kappa B and MAPK signaling pathways in mice mammary tissue. This indicates that Lactobacillus plantarum 17-5 has excellent anti-inflammatory activities and can be developed into a microecological preparation for clinical use to prevent mastitis.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Biotechnology & Applied Microbiology
J. Yang, Y. Qiu, S. Hu, C. Zhu, L. Wang, X. Wen, X. Yang, Z. Jiang
Summary: Pre-treatment with Lactobacillus plantarum can inhibit the inflammatory response induced by ETEC K88 in IPEC-1 cells and the activation of related signaling pathways.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Huan Wang, In-Ho Kim
Summary: Study shows that adding Lactobacillus plantarum BG0001 significantly improves the growth performance and fecal microbiota of weaned pigs, potentially replacing antibiotic growth promoters.
Article
Agriculture, Dairy & Animal Science
Leihong Cui, Hui Zeng, Meixin Hou, Zhongxin Li, Chunlong Mu, Weiyun Zhu, Suqin Hang
Summary: Alternatives to antibiotics are needed to prevent bacteria-induced inflammation in early-weaned farm animals. This study investigated the effects of Lactiplantibacillus plantarum L47 and inulin on the inflammatory response in weaned piglets challenged with enterotoxigenic Escherichia coli (ETEC). The results showed that L. plantarum L47 and inulin reduced inflammation and protected against ETEC-induced damage by up-regulating ALA and 12,13-EpOME levels via the LTA/TLR2/PLA2G2A pathway.
Article
Biotechnology & Applied Microbiology
Matej Hrala, Juraj Bosak, Lenka Micenkova, Jitka Krenova, Matej Lexa, Viktoria Pirkova, Zuzana Tomastikova, Ivana Kolackova, David Smajs
Summary: The study identified three potentially probiotic E. coli strains producing antimicrobial compounds that effectively inhibit pathogenic E. coli strains, showing promising results for preventing infections during the postweaning period of piglets.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Veterinary Sciences
Yuzeng Yang, Guohua Yan, Xianhua Meng, Xu Wang, Zhiqiang Zhao, Shuguang Zhou, Guangdong Li, Qiuliang Zhang, Xiaoyuan Wei
Summary: This study aimed to investigate the effects of fermented feed on the growth performance and gut microbiota of nursery pigs. The results showed that the fermented feed improved daily weight gain and significantly increased the concentration of acetate, butyrate, and total short-chain fatty acids in the feces. In addition, the addition of the fermented feed led to significant changes in the structure and membership of the gut microbiota. The study found that the fermented feed enriched beneficial bacteria that produce short-chain fatty acids, and some of these bacteria also had anti-inflammatory and other beneficial functions.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Food Science & Technology
Bo Peng, Qingyu Cui, Chao Ma, Huaxi Yi, Pimin Gong, Kai Lin, Tongjie Liu, Lanwei Zhang
Summary: Probiotics, specifically Lactiplantibacillus plantarum YZX28, have shown protective effects on intestinal barrier dysfunction caused by enterotoxigenic Escherichia coli K80 (ETEC K80), and may serve as potential therapeutic agents for intestinal-related problems.
Article
Microbiology
Ayelen Baillo, Julio Villena, Leonardo Albarracin, Mikado Tomokiyo, Mariano Elean, Kohtaro Fukuyama, Sandra Quilodran-Vega, Silvina Fadda, Haruki Kitazawa
Summary: The immunobiotic potential of L. plantarum CRL681 and CRL1506 was studied in this research. The results showed that both strains could induce the expression of IL-6 and IL-8 in intestinal epithelial cells and enhance the levels of IFN-gamma and TNF-alpha in mice. In addition, these strains could modulate the expression of inflammatory cytokines and chemokines, reduce the pathogen counts, and prevent its spread to other organs. L. plantarum CRL1506 was found to be more efficient in modulating mucosal immunity than CRL681.
Article
Microbiology
Djamel Drider, Rabah Boukherroub, Laetitia Le Devendec, Yanath Belguesmia, Noura Hazime, Gwenaelle Mourand, Frederic Paboeuf, Isabelle Kempf
Summary: This study evaluated the therapeutic efficacy of colistin-loaded alginate nanoparticles in the treatment of post-weaning diarrhoea. The results showed that the nanoparticles had a slightly better therapeutic effect compared to free colistin. However, further studies are needed to evaluate the efficacy of this novel drug in different settings.
VETERINARY MICROBIOLOGY
(2022)
Article
Microbiology
Jiameng Hu, Junlin Li, Xiaobo Huang, Jing Xia, Min Cui, Yong Huang, Yiping Wen, Yue Xie, Qin Zhao, Sanjie Cao, Likou Zou, Xinfeng Han
Summary: The study identified and characterized 19 enterotoxigenic Escherichia coli (ETEC) isolates from diarrheic pigs in China. The isolates showed high resistance to multiple antibiotics and carried various virulence factors. Genetic diversity was observed among the isolates, with certain serotypes being dominant. Hybrid ETEC/STEC isolates carrying Shiga-like toxin-related virulence factors were also identified. The presence of plasmids carrying antimicrobial resistance genes highlighted their role in the emergence of hybrid pathotypes. These findings emphasize the importance of controlling and intervening in porcine-origin ETEC strains to mitigate the impact on animal and human health.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Infectious Diseases
Fabio M. Carvalho, Rita Teixeira-Santos, Filipe J. M. Mergulhao, Luciana C. Gomes
Summary: This study evaluated the impact of Lactobacillus plantarum biofilms on Escherichia coli adhesion to medical-grade silicone, finding significant reductions in E. coli culturability. Analysis with CLSM and contact angle measurements indicated that L. plantarum cells have the potential to be used as antibiofilm agents for urinary tract applications.
Article
Veterinary Sciences
Ke Li, Ming Yang, Mengyue Tian, Li Jia, Jinliang Du, Yinghao Wu, Lianmin Li, Lining Yuan, Yuzhong Ma
Summary: The study showed that L. plantarum 17-5 had alleviative effects on the inflammatory response of bovine mammary epithelial cells induced by E. coli.
BMC VETERINARY RESEARCH
(2022)
Article
Agriculture, Dairy & Animal Science
Keying An, Wenwen Gao, Peng Li, Lei Li, Zhaofei Xia
Summary: This study found that dietary Lactobacillus plantarum (LP) improved the growth performance and intestinal health of Pekin ducks, with the 400 mg/kg LP dosage showing better effects.
Article
Gastroenterology & Hepatology
Weichun Xie, Liying Song, Xueying Wang, Yigang Xu, Zengsu Liu, Dongfang Zhao, Shubo Wang, Xiaolong Fan, Zhaorui Wang, Chong Gao, Xiaona Wang, Li Wang, Xinyuan Qiao, Han Zhou, Wen Cui, Yanping Jiang, Yijing Li, Lijie Tang
Summary: LR-LFCA can colonize the intestines of piglets, improve growth performance, enhance immune response, and benefit intestinal health by improving intestinal barrier function and modulating gut microbiota composition. LR-LFCA attenuated weight loss and diarrhea incidence in piglets infected with ETEC, by decreasing inflammation and oxidative stress, increasing tight junction proteins expression, and enhancing antioxidant capacity. LR-LFCA may activate MLCK and inhibit NF-kappa B pathways, providing a promising alternative therapeutic method for intestinal inflammation.
Article
Public, Environmental & Occupational Health
Yoshihiko Tanimoto, Miyoko Inoue, Kana Komatsu, Atsuyuki Odani, Takayuki Wada, Eriko Kage-Nakadai, Yoshikazu Nishikawa
Summary: The study found that E. coli expressing K88(O169) adhesin can infect different hosts including pigs and cattle, with the first report of domestic livestock having antibodies to K88(O169) of human ETEC; suggesting zoonotic strains may hide among human ETEC organisms, calling for the adoption of the One Health concept to intervene in ETEC infections among animals and humans.
EPIDEMIOLOGY AND INFECTION
(2021)
Article
Toxicology
Jane Tully Jones, Dereje D. Tassew, Lois K. Herrera, Stephanie R. Walton-Filipczak, Marena A. Montera, Hitendra S. Chand, Monica Delgado, Yohannes A. Mebratu, Yohannes Tesfaigzi
INHALATION TOXICOLOGY
(2017)
Article
Veterinary Sciences
Dereje Damte Tassew, Abraham Fikru Mechesso, Na-Hye Park, Ju-Beom Song, Joo-Woon Shur, Seung-Chun Park
JOURNAL OF VETERINARY MEDICAL SCIENCE
(2017)
Article
Veterinary Sciences
Wu-Sheng Sun, Ju-Lan Chun, Dong-Hwan Kim, Jin-Seop Ahn, Min-Kyu Kim, In-Sul Hwang, Dae-Jin Kwon, Seongsoo Hwang, Jeong-Woong Lee
JOURNAL OF VETERINARY SCIENCE
(2017)
Article
Obstetrics & Gynecology
Bo Myeong Lee, Ju Lan Chun, Ji Hye Lee, Eun Young Kim, Kang-sun Park, Jin-Hee Lee, Bradford W. Daigneault, George W. Smith, Keun Jung Kim, Kyu-Tae Chang, Sang-Rae Lee, Sun-Uk Kim, Seon-A Choi, Kyung-Bon Lee, Min Kyu Kim
REPRODUCTIVE SCIENCES
(2018)
Article
Multidisciplinary Sciences
Xiao-Xia Li, Yun-Fei Diao, Hai-Jun Wei, Shi-Yong Wang, Xin-Yan Cao, Yu-Fei Zhang, Tong Chang, Dan-Li Li, Min Kyu Kim, Baozeng Xu
SCIENTIFIC REPORTS
(2017)
Article
Biochemistry & Molecular Biology
Seon-A Choi, Young-Hyun Kim, Young-Ho Park, Hae-Jun Yang, Pil-Soo Jeong, Jae-Jin Cha, Seung-Bin Yoon, Ji-Su Kim, Bong-Seok Song, Jong-Hee Lee, Bo-Woong Sim, Jae-Won Huh, In-Sung Song, Sang-Rae Lee, Min-Kyu Kim, Jin-Man Kim, Yun Soo Bae, Kazuhiko Imakawa, Sun-Uk Kim, Kyu-Tae Chang
CELL DEATH AND DIFFERENTIATION
(2019)
Article
Oncology
Mathewos Tessema, Dereje D. Tassew, Christin M. Yingling, Kieu Do, Maria A. Picchi, Guodong Wu, Hans Petersen, Scott Randell, Yong Lin, Steven A. Belinsky, Yohannes Tesfaigzi
Article
Environmental Sciences
Dereje Tassew, Susan Fort, Yohannes Mebratu, Jacob McDonald, Hong Wei Chu, Hans Petersen, Yohannes Tesfaigzi
Summary: Exposure to wood smoke (WS) increases mucin expression more efficiently than exposure to cigarette smoke (CS), especially in a p53 pathway-dependent manner. The WS constituent oxalate can enhance mucin expression, particularly in individuals with a p53 arginine genotype, revealing potential mechanisms for increased risk of chronic bronchitis. Identifying responsible compounds and genetic variations could help estimate pollutant-related risks and improve lung disease management strategies.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2022)
Meeting Abstract
Critical Care Medicine
D. Tassew, Y. Tesfaigzi
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2019)
Meeting Abstract
Critical Care Medicine
Y. A. Mebratu, J. T. Jones, D. Tassew, T. J. Mariani, Y. Tesfaigzi
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2019)
Article
Agriculture, Multidisciplinary
Kang-Sun Park, Ju Lan Chun, Eun Young Kim, Ji Hye Lee, Hyung Suk Lee, Nobuhiko Yamauchi, Kyung-Bon Lee, Min Kyu Kim
JOURNAL OF THE FACULTY OF AGRICULTURE KYUSHU UNIVERSITY
(2018)
Article
Agriculture, Multidisciplinary
Lili Zhuang, Ju Lan Chun, Junbo Wu, Ji Hye Lee, Eun Young Kim, Bo Myoung Lee, Nobuhiko Yamauchi, Hyung Suk Lee, Min Kyu Kim
JOURNAL OF THE FACULTY OF AGRICULTURE KYUSHU UNIVERSITY
(2018)
Meeting Abstract
Critical Care Medicine
D. D. Tassew, Y. Tesfaigzi
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2017)
Meeting Abstract
Critical Care Medicine
J. T. Jones, Y. A. Mebratu, D. D. Tassew, Y. Tesfaigzi
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2017)
Article
Agriculture, Multidisciplinary
Chi Sun Yun, Ju Lan Chun, Jung Yu, Dong Eon Kim, Kang-Sun Park, Eun Young Kim, Ji Hye Lee, Kwang Bae Yoon, Nobuhiko Yamauchi, Seung-Hwan Lee, Min Kyu Kim
JOURNAL OF THE FACULTY OF AGRICULTURE KYUSHU UNIVERSITY
(2018)