Article
Agriculture, Dairy & Animal Science
Huanxian Cui, Lu Liu, Xiaojing Liu, Yongli Wang, Na Luo, Xiaodong Tan, Yuting Zhu, Ranran Liu, Guiping Zhao, Jie Wen
Summary: This study investigated the biochemical mechanism of intramuscular fat (IMF) deposition in chickens. It was found that increasing IMF content can improve the flavor and tenderness quality of chicken meat. The content of triglyceride (TG) was decisive for IMF deposition, and the increase in major fatty acid components in IMF mainly came from TGs. The findings of this study will guide the production of high-quality chicken meat.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Z. Zhuang, R. Ding, Y. Qiu, J. Wu, S. Zhou, J. Quan, E. Zheng, Z. Li, Z. Wu, J. Yang
Summary: This study identified a consistent QTL, additional genomic regions, and genes contributing to the genetic variance of IMF using a large sample size of genotyped pigs and genealogical information.
Article
Agriculture, Dairy & Animal Science
Zhi Cao, Maodou Xu, Shangzong Qi, Xinlei Xu, Wei Liu, Linyu Liu, Qiang Bao, Yang Zhang, Qi Xu, Wenming Zhao, Guohong Chen
Summary: This study investigated the lipid composition and metabolic pathways of goose meat, revealing changes in intramuscular fat deposition and lipid composition with age. Glyceride molecules showed significant changes and played a pivotal role in intramuscular fat deposition. Pathway analysis identified glycerophospholipid and glyceride metabolism as the most significant pathways associated with lipid changes during goose growth.
Article
Agriculture, Dairy & Animal Science
B. B. Wang, L. M. Hou, W. D. Zhou, H. Liu, W. Tao, W. J. Wu, P. P. Niu, Z. P. Zhang, J. Zhou, Q. Li, R. H. Huang, P. H. Li
Summary: The research identified significant SNPs associated with IFC in Suhuai pigs through GEMMA and LDAK methods, mainly distributed on SSC5, 3, and 7.
Article
Agriculture, Dairy & Animal Science
Ayman G. EL Nagar, Imen Heddi, Bolivar Samuel Sosa-Madrid, Agustin Blasco, Pilar Hernandez, Noelia Ibanez-Escriche
Summary: This study found that maternal genetic effects have an important impact on intramuscular fat content and fatty acid composition in rabbits. Through genome-wide association studies, potential candidate genes related to these traits were identified.
Article
Food Science & Technology
Nanthana Pothakam, Pantaporn Supakankul, Worrarak Norseeda, Guisheng Liu, Tawatchai Teltathum, Watcharapong Naraballobh, Trisadee Khamlor, Korawan Sringarm, Supamit Mekchay
Summary: This study verified the polymorphisms of porcine IL-1A and IL-6 genes and found their associations with intramuscular fat content and fatty acid composition in commercial crossbred pigs. The results indicated that these genes play an important role in lipid content and fatty acid composition in pig muscles, confirming their significance as candidate genes for fatty acid composition.
Article
Genetics & Heredity
Hao Li, Cineng Xu, Fanming Meng, Zekai Yao, Zhenfei Fan, Yingshan Yang, Xianglun Meng, Yuexin Zhan, Ying Sun, Fucai Ma, Jifei Yang, Ming Yang, Jie Yang, Zhenfang Wu, Gengyuan Cai, Enqin Zheng
Summary: This study analyzed the scoring results of flesh color and intramuscular fat in different time periods, revealing their genetic structure and identifying related genes and genetic loci, which is of great importance for improving pig meat quality traits.
Article
Agriculture, Dairy & Animal Science
Man Yang, Run Zhang, Xiance Liu, Guohua Shi, Hai Liu, Xinhua Hou, Lijun Shi, Lixian Wang, Longchao Zhang
Summary: In this study, candidate intramuscular fat (IMF) genes in Beijing Black pigs were identified using genome-wide association study and RNA-sequencing analysis. SLC4A7 on SSC13 and INSIG2, CCDC93, and DBI on SSC15 were identified as potential candidate genes for IMF in this population. Additionally, RNA-seq analysis revealed 534 differentially expressed genes and suggested the involvement of peroxisome proliferator-activated receptors and FoxO signaling pathway in IMF regulation. The DBI gene was identified as a crucial candidate gene for influencing IMF in Beijing Black pigs.
Article
Agricultural Engineering
Yue Xin, Jianjiang Ma, Jikun Song, Bing Jia, Shuxian Yang, Luyao Wu, Li Huang, Wenfeng Pei, Li Wang, Jiwen Yu, Man Wu
Summary: In this study, quantitative trait loci (QTLs) for cottonseed oil content and fatty acid components were identified using a genome-wide association study (GWAS) approach. Several stable QTLs related to oleic acid accumulation were identified, and candidate genes were suggested based on haplotype block analysis and linkage disequilibrium. The ectopic expression of one candidate gene resulted in reduced oil and oleic acid content. This research provides insights into the mechanism underlying cottonseed oil biosynthesis and offers potential tools for molecular breeding and genetic modification.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Agriculture, Dairy & Animal Science
Francisco Requena Domenech, Pilar Gomez-Cortes, Silvia Martinez-Miro, Miguel Angel de la Fuente, Fuensanta Hernandez, Andres Luis Martinez Marin
Summary: The study investigated the estimation of methane production in lambs fattened under intensive feeding systems based on their meat fatty acid composition, establishing a highly accurate predictive model. It revealed a clear correlation between fatty acid profile and methane emissions in lamb meat.
Article
Agriculture, Dairy & Animal Science
Eunjin Cho, Minjun Kim, Sunghyun Cho, Hee-Jin So, Ki-Teak Lee, Jihye Cha, Daehyeok Jin, Jun Heon Lee
Summary: The composition of fatty acids has a significant impact on the flavor and quality of meat. Previous research has mainly focused on pigs and cattle, with limited studies on chickens. This study conducted a genome-wide association study to identify candidate genes associated with fatty acid composition in chickens.
JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY
(2023)
Article
Engineering, Multidisciplinary
H. Wachta, K. Tereszkiewicz, L. Kulig
Summary: The study showed that the luminance measurement method is a reliable experimental tool for assessing intramuscular fat content, with results consistent with the Soxhlet chemical method.
Article
Biology
Supamit Mekchay, Nanthana Pothakam, Worrarak Norseeda, Pantaporn Supakankul, Tawatchai Teltathum, Guisheng Liu, Watcharapong Naraballobh, Trisadee Khamlor, Korawan Sringarm, Patcharin Krutmuang
Summary: The polymorphisms of porcine IFNA16 and TNFRSF19 genes were found to be associated with intramuscular fat content and fatty acid composition, suggesting their potential role in lipid deposition and fatty acid deposition in the muscle tissue of pigs.
Article
Genetics & Heredity
Qixin Guo, Lan Huang, Hao Bai, Zhixiu Wang, Yulin Bi, Guohong Chen, Yong Jiang, Guobin Chang
Summary: In this study, a genome-wide association study was conducted to identify genetic variants associated with meat quality in ducks. Several genes were found to be associated with fat, water, collagen, and protein content. These findings can serve as markers for meat quality and help improve breeding plans and selection strategies.
Article
Veterinary Sciences
Yuanlu Sun, Xu Lin, Qian Zhang, Yu Pang, Xiaohan Zhang, Xuelian Zhao, Di Liu, Xiuqin Yang
Summary: This study analyzed lncRNAs in pig muscles with different meat quality and identified 500 differentially expressed lncRNAs and 2094 protein-coding genes. Through KEGG analysis, fat deposition was found to be the main reason for the differential phenotype, with cGMP-PKG and VEGF signaling pathways being the most important. Key genes and transcription factors related to differential fat deposition were characterized, providing candidate genes crucial for meat quality and contributing to molecular-breeding strategies.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Multidisciplinary Sciences
Jesus Valdes-Hernandez, Yuliaxis Ramayo-Caldas, Magi Passols, Cristina Sebastia, Lourdes Criado-Mesas, Daniel Crespo-Piazuelo, Anna Esteve-Codina, Anna Castello, Armand Sanchez, Josep M. Folch
Summary: This study identified a list of candidate genes associated with fatty acid traits in pig muscle, including both well-known and novel genes. Additionally, it revealed the involvement of biological processes and pathways related to energy, lipid, and carbohydrate metabolism in the modulation of fatty acid compositions.
SCIENTIFIC REPORTS
(2023)
Article
Immunology
Maria Ballester, Teodor Jove-Junca, Afra Pascual, Sergi Lopez-Serrano, Daniel Crespo-Piazuelo, Carles Hernandez-Banque, Olga Gonzalez-Rodriguez, Yuliaxis Ramayo-Caldas, Raquel Quintanilla
Summary: The aim of this study was to investigate the genetic determinism of lymphocyte subpopulations in pigs and identify genomic regions and biomarkers associated with them. Staining peripheral blood mononuclear cells, the researchers found medium to high heritabilities for immune-cell-related traits and significant genetic correlations between certain lymphocyte populations. A genome-wide association study identified 32 SNPs on pig chromosomes SSC3, SSC5, SSC8, and SSCX associated with T-helper cells, memory T-helper cells, and gamma delta T cells. These findings enhance understanding of the genetic control of lymphocyte traits and have implications for improving immune responses and optimizing selection programs in pigs.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Angela Cristina da Fonseca de Oliveira, Saulo Henrique Webber, Yuliaxis Ramayo-Caldas, Antoni Dalmau, Leandro Batista Costa
Summary: Pigs are social animals with well-established social structures, but intensive production systems often neglect their social needs. Group housing can lead to increased aggression when pigs are mixed, but our study found that hierarchical classification influenced feeding behavior and resulted in possible compensation skills. Understanding the role of hierarchy is crucial for managing social interactions and promoting positive behaviors in group-housed pigs.
Article
Multidisciplinary Sciences
Angela Cristina da Fonseca de Oliveira, Leandro Batista Costa, Saulo Henrique Weber, Yuliaxis Ramayo-Caldas, Antoni Dalmau
Summary: This study aimed to investigate the effects of mixing management and gender on the social and non-social behavior, performance, and physiological parameters of pigs. The results showed that repeated regrouping significantly influenced social and feeding behavior, without severely affecting performance and physiological parameters. Additionally, different patterns of social and feeding behavior, agonistic interactions, and injury scores were observed between barrows and females.
Article
Multidisciplinary Sciences
Yron Joseph Yabut Manaig, Lourdes Criado-Mesas, Anna Esteve-Codina, Emilio Marmol-Sanchez, Anna Castello, Armand Sanchez, Josep M. M. Folch
Summary: The n-6/n-3 PUFA ratio in pig skeletal muscle affects the transcriptome expression related to muscle growth and immune pathways, as well as adipogenesis and immune response. Predicted miRNA-to-mRNA regulatory networks are involved in lipid metabolism, obesity, muscle growth, and protein degradation. The n-6/n-3 PUFA ratio differences revealed genes, miRNAs, and enriched pathways involved in lipid metabolism, cell proliferation, and inflammation.
Article
Agriculture, Dairy & Animal Science
Houssemeddine Srihi, David Lopez-Carbonell, Noelia Ibanez-Escriche, Joaquim Casellas, Pilar Hernandez, Sara Negro, Luis Varona
Summary: INGA FOOD, S.A. conducted a crossbreeding program to produce hybrid pigs, and studies revealed differences in litter size between reciprocal crosses, suggesting the presence of genomic imprinting effects. A multivariate gametic model was introduced to estimate the gametic correlations between paternal and maternal effects from different genetic backgrounds. The results showed distinct differences in the posterior distribution of gametic correlations between the two populations, which may explain the performance outcomes in the reciprocal crosses.
Article
Microbiology
Yuliaxis Ramayo-Caldas, Daniel Crespo-Piazuelo, Jordi Morata, Olga Gonzalez-Rodriguez, Cristina Sebastia, Anna Castello, Antoni Dalmau, Sebastian Ramos-Onsins, Konstantinos G. Alexiou, Josep M. Folch, Raquel Quintanilla, Maria Ballester
Summary: This study found that structural variants in the pig genome are associated with the diversity and composition of the pig gut microbiota. By analyzing whole-genome sequencing data, a CNV named DUP was found to be associated with richness and Shannon alpha-diversity of the fecal bacterial diversity. This association was validated using real-time quantitative PCR and confirmed in an independent crossbreed population. These results highlight the importance of considering host-genome structural variants as potential modulators of microbial ecosystems and identify ABCC2-DNMBP CNV as a host-genetic factor for the modulation of the pig fecal microbiota.
MICROBIOLOGY SPECTRUM
(2023)
Article
Genetics & Heredity
Carlos Hervas-Rivero, Houssemeddine Srihi, David Lopez-Carbonell, Joaquim Casellas, Noelia Ibanez-Escriche, Sara Negro, Luis Varona
Summary: This study conducted a genomic scan and identified eight genomic regions associated with inbreeding depression for litter size in two varieties of Iberian pigs. These regions contain relevant genes and suggest that the genetic determinism of inbreeding depression may be heterogeneous across the genome.
Article
Microbiology
M. Barone, Y. Ramayo-Caldas, J. Estelle, K. Tambosco, S. Chadi, F. Maillard, M. Gallopin, J. Planchais, F. Chain, C. Kropp, D. Rios-Covian, H. Sokol, P. Brigidi, P. Langella, R. Martin
Summary: The transmission of microorganisms from mother to offspring plays a critical role in the maturation of the gut barrier. C-section delivery disrupts this transmission and results in increased susceptibility to chemically induced inflammation in mice. The excessive exposure to a diverse microbiota in early life alters the immune response, disrupts gut homeostasis, and increases vulnerability to inflammation later in life.
Article
Agriculture, Dairy & Animal Science
Ayman G. EL Nagar, Imen Heddi, Bolivar Samuel Sosa-Madrid, Agustin Blasco, Pilar Hernandez, Noelia Ibanez-Escriche
Summary: This study found that maternal genetic effects have an important impact on intramuscular fat content and fatty acid composition in rabbits. Through genome-wide association studies, potential candidate genes related to these traits were identified.
Article
Biology
Daniel Crespo-Piazuelo, Herve Acloque, Olga Gonzalez-Rodriguez, Mayrone Mongellaz, Marie-Jose Mercat, Marco C. A. M. Bink, Abe E. Huisman, Yuliaxis Ramayo-Caldas, Juan Pablo Sanchez, Maria Ballester
Summary: Genome-wide association studies on pigs have identified millions of significant associations between genetic polymorphisms and the expression of genes in the duodenum, liver, and muscle. These findings shed light on the regulatory variations that shape end-trait phenotypes and provide valuable insights into molecular mechanisms.
Article
Agriculture, Dairy & Animal Science
Joan Calle-Garcia, Yuliaxis Ramayo-Caldas, Laura M. Zingaretti, Raquel Quintanilla, Maria Ballester, Miguel Perez-Enciso
Summary: This study evaluates the impact of different modeling strategies on the predictive capacity of porcine immunocompetence traits. It shows that overall (holobiont) models, including genotype and microbiota data, perform better than partial models. Host genotype is especially relevant for predicting adaptive immunity traits, while microbial composition is important for predicting innate immunity traits. Clustering microbial abundances does not necessarily increase predictive accuracy.
GENETICS SELECTION EVOLUTION
(2023)
Article
Microbiology
Cristina Sebastia, Josep M. Folch, Maria Ballester, Jordi Estelle, Magi Passols, Maria Munoz, Juan M. Garcia-Casco, Ana I. Fernandez, Anna Castello, Armand Sanchez, Daniel Crespo-Piazuelo
Summary: The gut microbiota is closely related to the composition of short-chain fatty acids in the host, with Prevotella spp. and Akkermansia spp. potentially serving as biomarkers for acetic and n-butyric acid levels, and Rikenellaceae RC9 gut group potentially influencing the fatty acid composition in backfat and muscle of the pig.
