Article
Biotechnology & Applied Microbiology
Ahmed M. Sallam, Henry Reyer, Klaus Wimmers, Francesca Bertolini, Adel Aboul-Naga, Camila U. Braz, Alaa Emara Rabee
Summary: Understanding the genomic features of local goat breeds in Egypt is crucial for successful breeding programs and conservation. This study identified genomic regions with selection signatures and detected runs of homozygosity, genomic inbreeding coefficients, and fixation index in different goat breeds. The results revealed differences in genomic structure and adaptation among breeds, providing valuable information for preservation and breeding programs.
Article
Agriculture, Dairy & Animal Science
Shen-He Liu, Xiao-Ya Ma, Faiz-Ul Hassan, Teng-Yun Gao, Ting-Xian Deng
Summary: The study used ROH analysis to evaluate genomic inbreeding patterns and levels in Mediterranean buffaloes, identifying ROH hotspots, candidate genes related to production traits, and genetic improvement potential through selective breeding.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Tomasz Szmatola, Artur Gurgul, Igor Jasielczuk, Ewa Oclon, Katarzyna Ropka-Molik, Monika Stefaniuk-Szmukier, Grazyna Polak, Iwona Tomczyk-Wrona, Monika Bugno-Poniewierska
Summary: This study examined the distribution of runs of homozygosity (ROH) in six different horse breeds, and found differences in the length, quantity, and frequency of ROH between breeds. The study also identified ROH islands, which may represent signals of recent selection events, and found several genes involved in important horse breed characteristics. The results can be used for further research in identifying markers unique to specific horse breed characteristics.
Article
Agriculture, Dairy & Animal Science
Bethany Pilon, Kelly Hinterneder, El Hamidi A. Hay, Breno Fragomeni
Summary: Inbreeding depression refers to the decreased fitness of offspring of closely related individuals, which is a common issue in the livestock industry. The relationship between homozygosity and decreased performance is complex and varies by chromosome. Evaluating inbreeding per individual regions of the genome and focusing on specific ROH with negative effects may help to avoid inbreeding depression and increase prediction accuracy in genomic selection programs.
Article
Agriculture, Dairy & Animal Science
Xudong Wu, Ren Zhou, Yuanlang Wang, Wei Zhang, Xianrui Zheng, Guiying Zhao, Xiaodong Zhang, Zongjun Yin, Yueyun Ding
Summary: This study analyzed the genome of the local Chinese pig breed AQ pigs using resequencing technology and found that inbreeding levels were a concern and influenced by artificial selection. The study also identified genes related to immune biological processes in the ROH islands of AQ pigs.
Article
Biodiversity Conservation
Wilber Hernandez-Montiel, Nubia Noemi Cob-Calan, Lilia E. Cahuich-Tzuc, Jose A. Rueda, Jorge Quiroz-Valiente, Victor Meza-Villalvazo, Roberto Zamora-Bustillos
Summary: This study analyzed the runs of homozygosity, inbreeding coefficient, and effective population size in Pelibuey sheep, and compared them between two groups of ewes. The results revealed that the length distribution of runs of homozygosity and the genes associated with prolificacy were located near LINGO2, FLRT2, ADGRB3, DGKG, DGKE, DGKB, and DGKI. These findings are important for understanding the economic activity of this species.
Article
Agriculture, Dairy & Animal Science
Shuaishuai Tian, Wendan Tang, Ziqi Zhong, Ziyi Wang, Xinfeng Xie, Hong Liu, Fuwen Chen, Jiaxin Liu, Yuxin Han, Yao Qin, Zhen Tan, Qian Xiao
Summary: In this study, the genetic variations and runs of homozygosity (ROH) of 235 Wenchang chickens were systematically investigated. The ROH of Wenchang chicken consists mainly of short segments, and the chickens exhibit relatively high genetic diversity. Additionally, several genes related to growth performance, stress resistance, meat traits, and fat deposition were identified. These findings are valuable for future breeding, conservation, and utilization of Wenchang and other chicken breeds.
Article
Genetics & Heredity
Anna Letko, Benoit Hedan, Anna Snell, Alexander C. Harris, Vidhya Jagannathan, Goran Andersson, Bodil S. Holst, Elaine A. Ostrander, Pascale Quignon, Catherine Andre, Tosso Leeb
Summary: Bernese mountain dogs are a large dog breed with a complex genomic architecture due to high levels of inbreeding and relatedness. They are multi-purpose companion and family dogs, but are predisposed to several genetic disorders. The analysis of whole-genome sequencing data revealed limited clustering between European and USA dogs and identified several fixed regions harboring genetic variants associated with morphological traits and diseases. The breed's strong predisposition to hematopoietic cancers may be attributed to the presence of immune cell-regulating genes in shared runs of homozygosity.
Article
Biotechnology & Applied Microbiology
Maryam Nosrati, Hojjat Asadollahpour Nanaei, Arash Javanmard, Ali Esmailizadeh
Summary: The study revealed patterns, distributions, and levels of ROHs in the sheep genome, with most ROHs being small and the level of genomic inbreeding relatively low. The inbreeding coefficients based on ROH increased with distance from Southwest Asia, with maximum values detected in North European breeds. Multiple ROH hotspots were identified across 25 different autosomes, with most detected genes related to growth, body weight, meat production, wool production, and pigmentation.
Article
Biochemistry & Molecular Biology
Lisa Dickel, Peter Arcese, Pirmin Nietlisbach, Lukas F. Keller, Henrik Jensen, Jane M. Reid
Summary: Immigration into small recipient populations is expected to alleviate inbreeding and increase genetic variation, with immigrants typically being outbred and unrelated to existing natives and each other. This can facilitate population persistence through genetic and/or evolutionary rescue.
Article
Veterinary Sciences
Nora Laseca, Antonio Molina, Manuel Ramon, Mercedes Valera, Florencia Azcona, Ana Encina, Sebastian Demyda-Peyras
Summary: The study evaluated the impact of increased inbreeding levels on mare fertility, showing a negative correlation between whole-genome homozygosity and fertility estimated breeding values. The analysis also revealed chromosome-level variability and stronger correlations in a reduced dataset of the 10% most and least fertile individuals. Furthermore, the study identified genomic regions associated with fertility, including candidate genes related to oocyte and embryo development.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Genetics & Heredity
Hendyel A. Pacheco, Attilio Rossoni, Alessio Cecchinato, Francisco Penagaricano
Summary: Intensive selection for improved productivity has led to increased inbreeding rates and decreased genetic diversity. Inbreeding negatively impacts male fertility. This study examined the presence of runs of homozygosity (ROH) in Italian Brown Swiss cattle and their association with bull fertility.
FRONTIERS IN GENETICS
(2023)
Article
Genetics & Heredity
Yifei Fang, Xinyu Hao, Zhong Xu, Hao Sun, Qingbo Zhao, Rui Cao, Zhe Zhang, Peipei Ma, Yanxiao Sun, Zengmin Qi, Qingkui Wei, Qishan Wang, Yuchun Pan
Summary: Through analyzing data from Genotyping by Genome Reducing and Sequencing, the study found a high level of inbreeding in Laiwu pigs and identified genes associated with economically important traits.
FRONTIERS IN GENETICS
(2021)
Article
Biochemistry & Molecular Biology
Andrew D. Foote, Rebecca Hooper, Alana Alexander, Robin W. Baird, Charles Scott Baker, Lisa Ballance, Jay Barlow, Andrew Brownlow, Tim Collins, Rochelle Constantine, Luciano Dalla Rosa, Nicholas J. Davison, John W. Durban, Ruth Esteban, Laurent Excoffier, Sarah L. Fordyce Martin, Karin A. Forney, Tim Gerrodette, M. Thomas P. Gilbert, Christophe Guinet, M. Bradley Hanson, Songhai Li, Michael D. Martin, Kelly M. Robertson, Filipa I. P. Samarra, Renaud de Stephanis, Sara B. Tavares, Paul Tixier, John A. Totterdell, Paul Wade, Jochen B. W. Wolf, Guangyi Fan, Yaolei Zhang, Phillip A. Morin
Summary: Runs of homozygosity (ROH) reflect population history in killer whales, with shorter ROH indicating high relatedness between populations due to ancestral declines in effective population size, while longer and younger ROH mainly found in low latitude populations and those of known conservation concern. This suggests a potential link between demographic history, inbreeding depression, and the fate of certain killer whale populations.
Article
Agriculture, Multidisciplinary
Shi-feng Tong, Zhu Mo, Xie Rui, Dong-feng Li, Li-fan Zhang, Liu Yang
Summary: This study investigated the genetic structure and inbreeding level of three indigenous pig breeds in the Chinese Taihu Basin. It found significant differences in genetic structure among the breeds and identified candidate genes associated with reproductive traits in regions with a high frequency of runs of homozygosity (ROH). These findings provide theoretical support for genetic conservation and improvement of these pig breeds.
JOURNAL OF INTEGRATIVE AGRICULTURE
(2022)
Article
Agriculture, Dairy & Animal Science
J. A. P. Marchesi, A. M. G. Ibelli, J. O. Peixoto, M. E. Cantao, J. R. C. Pandolfi, C. M. M. Marciano, R. Zanella, M. L. Settles, L. L. Coutinho, M. C. Ledur
Article
Multidisciplinary Sciences
Leticia Borges Joaquim, Tatiane Cristina Seleguim Chud, Jorge Augusto Petroli Marchesi, Rodrigo Pelicioni Savegnago, Marcos Eli Buzanskas, Ricardo Zanella, Mauricio Egidio Cantao, Jane Oliveira Peixoto, Monica Correa Ledur, Renato Irgang, Danisio Prado Munari
Article
Veterinary Sciences
Daniel Lazzari Quadros, Ricardo Zanella, Carlos Bondan, Giovana Ciacci Zanella, Fernanda Luiza Facioli, Arthur Nery da Silva, Eraldo Lourenso Zanella
RESEARCH IN VETERINARY SCIENCE
(2020)
Article
Genetics & Heredity
Arthur Nery da Silva, Luana Alves, Germana Vizzotto Osowski, Leandro Sabei, Priscila Assis Ferraz, Guilherme Pugliesi, Mariana Groke Marques, Ricardo Zanella, Adroaldo Jose Zanella
Summary: The study found that an acute health challenge on the estrus day alters CL gene expression, particularly with significant downregulation of angiogenic genes VEGF and FTL1 among animals challenged with LPS, and upregulation of the HSD3B1 gene. Furthermore, differences in housing systems also resulted in variations in the expression of STAR and LHCGR genes.
Article
Agriculture, Dairy & Animal Science
Liliane Zanatta, Renata Rebesquini, Ricardo Zanella, Leonardo Porto Alves, Carlos Bondan
Summary: The effectiveness of a lactation induction protocol on milk production and its composition was evaluated in this study. The induced group showed a production of 17.9 +/- 5.8 liters/cow/day, equivalent to 67.54% of the control group. The induced group had a higher percentage of solids, fat, protein, and somatic cells.
Article
Agriculture, Dairy & Animal Science
Agatha Decroix Cordeiro, Ana Julia B. Conterato, Ivan Bianchi, Debora L. A. Dartora, Ricardo Zanella, Carlos Bondan, Mariana G. Marques, Bernardo G. Gasperin, Thomaz Lucia Jr
Summary: Lactation was induced in non-pregnant gilts using a specific protocol. The milk produced had lower fat content and higher protein content.
REPRODUCTION IN DOMESTIC ANIMALS
(2023)
Article
Cell Biology
Flavia de Marchi, Renan Lazzaretti, Janine de Camargo, Fernanda Luiza Facioli, Eraldo Lourenso Zanella, Pedro Nacib Jorge-Neto, Mariana Groke Marques, Kyle Cody Caires, Ricardo Zanella
Summary: The production of in vitro embryos has accelerated the propagation of superior genetic material, but the variation in cattle response to oocyte and embryo production poses a challenge, particularly in Wagyu cattle with a small population size. This study aimed to evaluate the association of blood levels of anti-Mullerian hormone (AMH) with oocyte recovery and blastocyst rate in Wagyu cows, as well as observe the hormone levels in males.
Article
Cell Biology
A. R. Moura, A. R. Santos, J. D. A. Losano, A. F. P. Siqueira, T. R. S. Hamilton, R. Zanella, K. C. Caires, R. Simoes
Summary: Our study found that Wagyu bulls have lower sperm motility compared to Nellore and Angus bulls, but did not differ in terms of plasma and acrosome membranes integrity, mitochondrial potential, chromatin resistance, sperm lipid peroxidation, or hormone (LH and testosterone) concentrations.
Article
Veterinary Sciences
Diorges H. Setim, Carlos Bondan, Caroline C. Cortese, Jessica C. Peretti, Fernanda L. Facioli, Ricardo Zanella, Marcio M. Costa, Adriana C. da Motta
Summary: This study aimed to verify the presence of bovine paratuberculosis in commercial dairy herds in different mesoregions of RS, Brazil. Indirect ELISA tests and PCR were performed on milk and fecal samples, respectively. The results indicated that paratuberculosis is likely endemic in the northwest and northeast mesoregions.
PESQUISA VETERINARIA BRASILEIRA
(2023)
Article
Agriculture, Dairy & Animal Science
Pedro Nacib Jorge-Neto, Thiago Cavalheri Luczinski, Gediendson Ribeiro de Araujo, Leticia Alecho Requena, Rogerio Silva de Jesus, Larissa Schneider Brandao Souza, Ricardo Zanella, Eliane Vianna da Costa e Silva, Thyara de Deco-Souza, Cristiane Schilbach Pizzutto
Summary: The cryopreservation of jaguar semen using glycerol has resulted in a significant reduction in sperm quality. This study aimed to evaluate the efficacy of three cryoprotectants (DMSO, GLY, and MET) and the effect of thawing temperature on dosage quality. The results showed that DMSO and GLY performed better than MET, and there was no significant difference in thawing temperature. Additionally, the commonly used morphological classification for bovines may not be applicable to felid species.
ANIMAL REPRODUCTION
(2023)
Article
Agriculture, Dairy & Animal Science
Maite Cardoso Coelho da Silva, Karitha Marques Ullony, Gediendson Ribeiro de Araujo, Pedro Nacib Jorge-Neto, Veronica Batista Albuquerque, Simone Marques Caramalac, Alice Rodrigues de Oliveira, Ricardo Zanella, Mariana Groke Marques, Antonio Carlos Csemark-Junior, Thiago Cavalheri Luczinski, Fabricio de Oliveira Frazilio, Eliane Vianna da Costa e Silva, Thyara de Deco-Souza
Summary: This study compared the efficacy of detomidine and medetomidine in collecting semen from domestic cats, with medetomidine showing higher success rates and sperm concentration. Although detomidine may be an alternative in cases where medetomidine is not accessible, it exhibited lower performance in semen collection.
ANIMAL REPRODUCTION
(2021)
Article
Veterinary Sciences
C. Bondan, J. A. Folchini, L. Guimaraes, M. Noro, R. Zanella, L. P. Alves, R. S. Fontaneli, F. Gonzalez
Summary: In this study, there were no significant differences in milk yield and composition between cows with clinical disorders, subclinical disorders, and healthy cows. Cows with clinical disorders had higher milk fat and F:P ratio, and lower lactose levels.
ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA
(2021)
Article
Agriculture, Dairy & Animal Science
Fernanda Luiza Facioli, Gabriela da Fonseca Bezutti, Rodrigo Saraiva Bender, Mariana Groke Marques, Carlos Bondan, Eraldo Lourenso Zanella, Marcelo Bertolini, Ricardo Zanella
ANIMAL REPRODUCTION
(2020)
Article
Veterinary Sciences
Fernanda L. Facioli, Flavia De Marchi, Mariana G. Marques, Paulo R. P. Michelon, Eraldo L. Zanella, Kyle C. Caires, Jerry J. Reeves, Ricardo Zanella
VETERINARY SCIENCES
(2020)
Article
Veterinary Sciences
Lays Wouters Ugolini, Fernanda Carlini Cunha dos Santos, Gabriela Vicensi da Costa, Henrique Ramos Oliveira, Natalia Folchini, Tanise Policarpo Machado, Ricardo Zannella, Leonardo Porto Alves
ACTA SCIENTIAE VETERINARIAE
(2019)