Article
Chemistry, Applied
Vahid Ashouri, Kourosh Adib, Gilan Attaran Fariman, Mohammad Reza Ganjali, Mehdi Rahimi-Nasrabadi
Summary: The synthesis and application of task-specific ionic liquids as extracting solvents or chelating agents in dispersive liquid-liquid micro-extraction (DLLME) were evaluated. The method involved chelation of As(III) with an ammonium pyrrolidine dithiocarbamate (APDC) bonded ionic liquid followed by conversion to a hydrophobic ionic liquid and determination of As levels through ETAAS analysis. Under optimal conditions, linear dynamic ranges and low limits of detection were achieved for both As(III) and total As.
Article
Chemistry, Analytical
Fuad Ameen, Abeer A. Al-Masri
Summary: A rapid and environmentally friendly liquid phase microextraction method using pH-switchable hydrophobic deep eutectic solvents (HDESs) and HPLC-FL was proposed for the quantitative analysis of aflatoxin B1 (AFB1) in cereal samples. Six different DESs were synthesized and their pH-switchability was investigated. The DESs that could switch with pH were used for the separation and preconcentration of AFB1. The method demonstrated good precision, with relative standard deviation values of 3.3% and 5.2% for intra-day and inter-day measurements, respectively, and a limit of detection of 0.002 μg/kg.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Xiaochong Song, Siyu Luo, Jun Liu, Yuanfei Wu, Xiaojia Huang
Summary: Efficient separation and enrichment of Se(iv) and Se(vi) species in water samples were achieved in this study using online monolith-based magnetic field-assisted in-tube solid phase microextraction (MFA/IT-SPME). The application of a magnetic field during the extraction procedure significantly improved the extraction efficiency. The developed method combined with HPLC allowed for the quantification of Se(iv) and Se(vi) in environmental water samples with satisfactory results.
Article
Chemistry, Analytical
Valfredo Azevedo Lemos, Jeferson Alves Barreto, Luana Bastos Santos, Rosivan dos Santos de Assis, Cleber Galvao Novaes, Ricardo J. Cassella
Summary: Dispersive liquid-liquid microextraction (DLLME) is widely used for the separation and preconcentration of various chemical species, with some systems using a syringe as an extraction environment. This review discusses methods utilizing this approach, critical aspects like dispersion promotion, analytical characteristics, and the pros and cons of the methods, as well as future trends in in-syringe microextraction systems.
Article
Chemistry, Analytical
Nisha Sharma, Pragati Thakur, Manohar G. Chaskar
Summary: Endocrine disrupting chemicals interfere with the hormonal system and can inhibit reproductive activity. A new method was developed for the determination of eight potential endocrine disruptor pesticides in milk samples, showing high efficiency and sensitivity. The study highlighted the importance of monitoring these chemicals in food products.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Juan J. Pinto, Victoria Manuel, Carlos Moreno
Summary: Supported liquid membranes were used to preconcentrate Cd(II) in natural waters for its determination by HR-CS-GFAAS. Four hollow fibres were simultaneously used with the same sample, improving the simplicity, speed, and reproducibility of the results. Bis-(2,4,4-trimethylpentyl) phosphinic acid (Cyanex((R)) 272) dissolved in dihexylether (DHE) was immobilised in the pores of polypropylene hollow fibres. The optimized extraction process achieved an enrichment factor (EF) of 292 with a detection limit of 0.13 ng L-1 Cd(II) and a linear range up to 3 mu g L-1.
Article
Environmental Sciences
Dotse Selali Chormey
Summary: This study presents a liquid phase microextraction method using binary extraction solvents for preconcentration of chlorbenside and fenobucarb from aqueous samples. The optimized parameters resulted in high enrichment factors for the analytes. The method was validated and successfully applied to lake water and wastewater samples, showing accurate quantification and applicability. The use of matrix matching calibration method improved the accuracy for quantifying the analytes in wastewater samples with interference effects. The method was also confirmed as compliant with green analytical chemistry.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Analytical
Adrian Garcia-Figueroa, Stanislav Musil, Tomas Matousek
Summary: An automated and high-throughput method for sensitive determination of tellurium species in the environment, using flow injection hydride generation interfaced with inductively coupled plasma triple quadrupole mass spectrometry, was developed. The method showed excellent sensitivity and repeatability, and was successfully applied to the analysis of real samples.
ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Multidisciplinary
Muhammad Saqaf Jagirani, Mustafa Soylak
Summary: Arsenic is a hazardous element that causes environmental pollution, so it is important to quantify and minimize its impact on the ecology. Sample preparation is crucial for determining target analytes in complex matrices. Microextraction techniques have emerged as a green alternative to traditional sample preparation methods, offering improved extraction efficacy, faster processes, lower solvent consumption, and environmental suitability.
TURKISH JOURNAL OF CHEMISTRY
(2023)
Article
Food Science & Technology
Rebagamang Tshepho, Simiso Dube, Mathew M. M. Nindi
Summary: An ionic liquid-based dispersive liquid-liquid microextraction (IL-DLLME) method coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed, optimized, and validated for the analysis of 20 anthelmintic drugs. Various parameters affecting the extraction efficiency were optimized, and the method was validated according to relevant regulations. The method demonstrated high calibration function values, low LODs and LOQs, and reliable precision. A comparison was made with the standard QuEChERS method, and the IL-DLLME LC-MS/MS method was successfully applied to analyze anthelmintic residues in small stock liver samples.
FOOD SCIENCE & NUTRITION
(2023)
Article
Spectroscopy
Daichun He, Xiaofang Yang, Rui Zhang, Ting Xia, Yong Liu, Shengchun Yang, Kan Hu, Zhengui Li, Xiaodong Wen
Summary: In this study, a rapid synergistic cloud point extraction (RS-CPE) based on deep eutectic solvent (DES) was developed and coupled with inductively coupled plasma optical emission spectrometry (ICP-OES). The method was successfully applied to simultaneously determine Cd and Ni in the medicinal plant Salvia yunnanensis C. H. Wright (S. yunnanensis). Compared with traditional CPE, RS-CPE achieved rapid extraction at room temperature and utilized an environmentally friendly cloud point and synergic reagent. The method showed improved analytical performance with enhanced limits of detection and quantification, as well as satisfactory spiked recoveries. This method provides a simple, rapid, sensitive, and green approach for the determination of potentially toxic elements in medicinal herbs.
ATOMIC SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Xiangdong Ding, Chao Liu, Wei Yu, Zhongling Liu
Summary: A green, efficient and easy method combining magnetic ionic liquid-based liquid-liquid microextraction (MIL-based LLME) with ultraperformance liquid chromatography coupled with triple-quadrupole tandem mass spectrometry (UPLC-QqQ/ MS2) was developed for simultaneous determination of neurotransmitters (NTs) in biosamples. The selected magnetic ionic liquid [P6,6,6,14]2[CoCl4] showed advantages of visual recognition, paramagnetic behavior and higher extraction efficiency. The proposed method achieved facile magnetic separation of MIL containing analytes from matrix and successfully extracted and determined 20 NTs in human cerebrospinal fluid and plasma samples. The excellent analytical performance suggests the broad potential of this method for clinical diagnosis and therapy of neurological diseases.
Article
Chemistry, Analytical
Ramin Ghasemi, Hamid Mirzaei, Mohammad Reza Afshar Mogaddam, Jalil Khandaghi, Afshin Javadi
Summary: This research proposes a magnetic ionic liquid-based air-assisted liquid-liquid microextraction method for the preconcentration and determination of seven multiclass antibiotics. The method demonstrates wide linear ranges, high enrichment factors, and extraction recoveries, as well as low limits of detection and quantification. The method was successfully applied for the quantification of antibiotics in milk samples marketed in Tabriz city, Iran.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Reyla A. S. Dias, Eliane R. Sousa, Gilmar S. Silva, Lanna K. Silva, Arlan S. Freitas, Diana L. D. Lima, Erika M. L. Sousa
Summary: This study developed an HPLC-FLD methodology for the separation of fluoroquinolones and optimized the DLLME process for clean-up and preconcentration of enrofloxacin in water samples. The method showed successful results in samples with low salinity content.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
B. Krasnodebska-Ostrega, A. Drwal, E. Biadun, J. Kowalska
Summary: This paper presents a simple and quick procedure for the separation and analysis of As(iii) species in water systems. By using a C18 column saturated with APDC and acidified water samples, As(iii) anions can be effectively separated and the influence of other metal cations can be limited.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Chemistry, Applied
Emiliano F. Fiorentini, Maria B. Botella, Rodolfo G. Wuilloud
Summary: A highly efficient preconcentration method based on dispersive liquid-liquid microextraction technique with a magnetic ionic liquid was developed to determine ultra-trace levels of lead in various honey products. The method allowed for phase separation without centrifugation, reducing analysis time and simplifying the process. High extraction efficiency, sensitivity enhancement, and low detection limit were achieved under optimal conditions.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Article
Biochemistry & Molecular Biology
Paula Berton, Noureen Siraj, Susmita Das, Sergio de Rooy, Rodolfo G. Wuilloud, Isiah M. Warner
Summary: This study developed a liquid-liquid microextraction technique using magnetic ionic liquids to successfully extract four types of estrogens from environmental water. The optimized method showed good performance in terms of detection limits, linear range, and stability.
Editorial Material
Spectroscopy
Rodolfo G. Wuilloud, Patricia Smichowski
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Review
Chemistry, Analytical
Maria N. Oviedo, Emiliano F. Fiorentini, Mauricio Llaver, Rodolfo G. Wuilloud
Summary: Alternative solvents have gained increasing attention for sample preparation, replacing traditional organic solvents and developing simpler, more environmentally friendly methods for trace element determination. Ionic liquids and surfactants have been the most studied solvents, while deep eutectic and switchable-hydrophilicity solvents have been increasingly explored.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Mauricio Llaver, Maria N. Oviedo, Emiliano F. Fiorentini, Pamela Y. Quintas, Rodolfo G. Wuilloud
Summary: Ionic liquids (ILs) have been widely used in analytical chemistry, leading to significant improvements in sample preparation, mass spectrometry, electrode preparation, and separation techniques. The combination of ILs with modern materials has greatly enhanced sensitivity and selectivity in electroanalytical methods.
TRENDS IN ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Applied
Maria B. Perez, Victor M. Lipinski, Maria F. Fillipini, Katherine Chacon Madrid, Marco A. Zezzi Arruda, Rodolfo G. Wuilloud
Summary: This study found that garlic has a significant ability to accumulate and metabolize selenium, especially in red clones. Selenium-amino acids were mainly found in garlic bulbs, indicating potential biological properties.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2021)
Article
Food Science & Technology
Pamela Y. Quintas, Sonia Keunchkarian, Lilian Romero, Brenda Canizo, Rodolfo G. Wuilloud, Cecilia B. Castells
Summary: The study analyzed the amino acid content in honey samples from Mendoza using high-performance liquid chromatography and chiral gas chromatography coupled to mass spectrometry. Proline and phenylalanine were found to be the most abundant amino acids. The results also showed that certain D-amino acids can occur naturally in honey samples from Mendoza. Chemometric tools were applied to differentiate samples from different geographical origins.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2021)
Article
Engineering, Chemical
Gustavo D. Rosales, Alexander C. J. Resentera, Rodolfo G. Wuilloud, Mario H. Rodriguez, Marcelo R. Esquivel
Summary: This study investigated the optimization of Li extraction process from low-grade alpha-spodumene ore through mechanical activation and leaching with NaF solution. The results showed that the mechanical activation time, reaction temperature, and leaching time had a positive effect on lithium extraction efficiency. The optimum Li extraction rate was achieved at 81% with a mechanical activation time of 600 minutes, a temperature of 90 degrees C, and a leaching time of 240 minutes.
MINERALS ENGINEERING
(2022)
Article
Chemistry, Analytical
Mauricio Llaver, Santiago D. Barrionuevo, Eduardo Prieto, Rodolfo G. Wuilloud, Francisco J. Ibanez
Summary: In this study, a sensitive and selective detection method for Hg2+ using functionalized graphene quantum dots (GQDs) through front-face fluorescence was reported. The method showed excellent performance even under adverse conditions and in the presence of interferences.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Physical
Brenda V. Canizo, Pamela Y. Quintas, Rodolfo G. Wuilloud, Maria Fernanda Silva, Federico J. V. Gomez
Summary: This research provides the first comprehensive study on the fluorescence characteristics of melatonin and its derivatives in natural deep eutectic solvents. The results show differential fluorescence behavior of melatonin and its metabolic precursors in these solvents, which could inspire the development of new analytical approaches.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Spectroscopy
Maria N. Oviedo, Maria B. Botella, Emiliano F. Fiorentini, Pablo Pacheco, Rodolfo G. Wuilloud
Summary: A highly selective and efficient method using graphene oxide (GO) and a magnetic ionic liquid (MIL) for dispersive micro-solid phase extraction (D-mu-SPE) of inorganic Sb speciation analysis was developed. Sb(III) was complexed with sodium diethyldithiocarbamate (DDTC) and retained on GO, followed by magnetization of the sorbent surface with MIL and separation using a magnetic rod. The aqueous phase containing only Sb(V) was directly analyzed by ICP-MS. The method showed high extraction efficiency, low limits of detection, and good precision for Sb(III) and Sb(V) determination. It was successfully applied in the analysis of inorganic Sb species in tap water, tea infusions, and honey samples. The method also demonstrated good environmental performance according to the Analytical GREEnness calculator (AGREE) with a value of 0.61.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Review
Chemistry, Analytical
Pamela Y. Quintas, Emiliano F. Fiorentini, Mauricio Llaver, Roxana E. Gonz, Rodolfo G. Wuilloud
Summary: This review provides a comprehensive overview of the latest developments in enantiomeric separation using alternative solvents, with a focus on the application of chiral ionic liquids (CILs). The separation and pre-concentration of chiral analytes in different matrices are also reviewed in this article.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Estefania B. Ingrassia, Emiliano F. Fiorentini, Rodolfo G. Wuilloud, Stela M. da Silva, Leticia B. Escudero
Summary: A new hybrid bionanomaterial composed of graphene oxide (GO) and Spirulina maxima (SM) algae was synthesized and applied to develop a preconcentration method based on the dispersive micro-solid phase extraction (D-mu-SPE) technique for the determination of Pb in water and infant beverages.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Plant Sciences
Irene Serrano-Garcia, Joel Dominguez-Garcia, Elena Hurtado-Fernandez, Jose Jorge Gonzalez-Fernandez, Jose Ignacio Hormaza, Maria Gemma Beiro-Valenzuela, Romina Monasterio, Romina Pedreschi, Lucia Olmo-Garcia, Alegria Carrasco-Pancorbo
Summary: Spain dominates avocado production in Europe, but its production satisfies less than 10% of the European demand, leading to heavy reliance on imports from Peru and Chile. This study characterized the metabolic profile of Hass avocados from Spain, Peru, and Chile in the European market throughout the year. Significant differences in phenolic compounds, amino acids, and nucleosides were observed, and avocados from each country exhibited specific metabolic patterns.
Article
Chemistry, Analytical
Maria N. Oviedo, Emiliano F. Fiorentini, Aldana A. Lemos, Rodolfo G. Wuilloud
Summary: This study achieved efficient separation and preconcentration of inorganic Sb species in different water samples using a novel DLLME method based on MIL and ETAAS, showing high sensitivity and selectivity. Multivariate study was conducted to obtain optimal extraction conditions, and the method demonstrated excellent analytical performance.
ANALYTICAL METHODS
(2021)
Article
Chemistry, Analytical
Michelle Buoso, Beatrice Campanella, Massimo Onor, Emanuela Pitzalis, Alessandro D'Ulivo
Summary: The use of BH intermediates as derivatization reagents significantly improves the tolerance to interference from transition metal ions in the generation of SbH3 and BiH3, and shows high tolerance in a wide range of acidity. The method has been successfully applied to the determination of Sb and Bi in complex samples, providing further understanding of the chemical behavior of borohydrides.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)
Article
Chemistry, Analytical
Chao-Feng Li, Xuan-Ce Wang, Zhu-Yin Chu, Peng Peng
Summary: Thermal ionization mass spectrometry (TIMS) is the standard method for obtaining precise Sr-87/Sr-86 isotopic ratios. However, our developed hydrofluoric acid coprecipitation method offers a low-cost, rapid, simple, and high-throughput alternative for analyzing red wine samples, effectively eliminating isobaric interference and matrix element inhibition.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)
Article
Chemistry, Analytical
Ivan B. Krstic, Bratislav M. Obradovic, Milorad M. Kuraica
Summary: This paper presents the spatio-temporal dynamics of a Grimm-type microsecond pulsed glow discharge (mu PGD) in argon at 6 mbar. The occurrence of a high current peak during the discharge ignition is analyzed and the importance of displacement current is emphasized. The development of electron excitation temperature for argon atoms and ions at various distances from the cathode is measured. The spatio-temporal evolution of selected spectral lines of argon and copper atoms and ions is analyzed during different phases of the discharge. The results suggest that the behavior of spectral line emissions differs between the pre-peak and afterglow periods, with different lines reaching maximum intensity during these phases. The appearance time and decay time of the afterpeak are shorter for ions than for atoms. These findings are explained in terms of three-body recombination processes and ion mobilities.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)
Article
Chemistry, Analytical
Qiuyun Wang, Anmin Chen, Xun Gao
Summary: In this paper, the combination of Tesla coil discharge (TCD) and laser-induced breakdown spectroscopy (LIBS) was used to enhance the emission of Al atomic lines and AlO molecular bands. The optimized distance between the TCD tip and the sample surface was found to be 5 mm, and the optimal laser energy was 25.1 mJ. Furthermore, TCD-SELIBS showed lower limits of detection (LoDs) for Cr and Pb elements compared to surface enhanced LIBS (SELIBS). The combination of TCD and LIBS is a promising technology for high-sensitivity analysis of heavy metals in water, with the advantages of simplicity, low cost, ease of operation, industrialization, and commercialization.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)
Article
Chemistry, Analytical
Yanwen Tang, Tingguang Lan, Jianfeng Gao, Zhongjie Bai, Xiaowen Huang, Junjie Han, Na Liu
Summary: Titanium is an important metal widely used in various industries. Ilmenite minerals are the main source of titanium metal and can be found in igneous and metamorphic rocks as well as different types of deposits. To accurately determine U-Pb ages of ilmenite, a new calibration method and appropriate reference materials are urgently needed. Laser ablation sector field inductively coupled plasma mass spectrometry has been used to minimize matrix effects and zircon 91500 has been identified as a suitable reference material for measuring the Pb/U ratio in ilmenite. The direct calibration method using zircon 91500 as an external standard has been found to be effective for in situ U-Pb dating of ilmenite samples under different ablation settings.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)