Review
Metallurgy & Metallurgical Engineering
Yuchien Hsu, Yupu Lu, Siyi Wang, Yufeng Zheng, Dandan Xia, Yunsong Liu
Summary: Magnesium alloys have great potential in tumor treatments due to their acceptable mechanical properties, good osteogenic and angiogenic properties. They can exhibit antitumor effect on various types of tumors and promote tissue regeneration after tumor elimination.
JOURNAL OF MAGNESIUM AND ALLOYS
(2023)
Review
Multidisciplinary Sciences
Juexuan Chen, Huanjie Li, Dayuan Zhong, Fangwei Xu, Lu Ding, Chunzhi Tang, Chunguang Guan, Liming Lu, Jian Deng
Summary: A bibliometric analysis was conducted on research articles on acupuncture for neurodevelopmental disorders. The study found an increasing research intensity and collaboration within this field. The neuro-endocrine-immune mechanism emerged as a new direction for further development. More basic research is needed to elucidate the therapeutic mechanisms and standardize the use of acupuncture for neurodevelopmental disorders.
Review
Environmental Sciences
Yujun Chen, Bin Guan, Xingze Wu, Jiangfeng Guo, Zeren Ma, Jinhe Zhang, Xing Jiang, Shibo Bao, Yiyan Cao, Chengdong Yin, Di Ai, Yuxuan Chen, He Lin, Zhen Huang
Summary: With global climate change, the utilization of carbon dioxide as a resource to achieve carbon peaking and carbon neutrality has gained significant attention. Photocatalysis, as an emerging discipline, relies solely on sunlight and has unique properties and mechanisms. The development of photocatalysts with high activity, selectivity, cost-effectiveness, and durability is crucial.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Psychology, Multidisciplinary
Peixu He, Cuiling Jiang, Zhixing Xu, Chuangang Shen
Summary: This review article analyzes scientific articles on knowledge hiding in organizations, identifying the main areas and current dynamics of research in this field. The study found that the central research themes of knowledge hiding include concept and dimensions, antecedents, consequences, theories, and influence mechanisms. Future research should focus on further developing the concept and dimensions of knowledge hiding, exploring its consequences, employing innovative theoretical perspectives and research methods, and considering cultural and contextual factors influencing knowledge hiding behavior.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Psychiatry
Xiang Li, Ji-Cheng Li, Qi-Qi Lu, Fan Zhang, Shan-Qiang Zhang
Summary: Autism spectrum disorder (ASD) is a neurodevelopmental disorder that primarily affects children. The symptoms of ASD, which include lifelong social communication deficits and repetitive sensory-motor behaviors, have a significant impact on the patient's family and society. While acupuncture has shown potential as a complementary therapy for ASD, current clinical studies do not provide enough evidence to support its effectiveness. However, further research with rigorous scientific designs and adherence to reporting standards may provide more conclusive results. This review is important as it provides a reference for researchers to conduct high-quality clinical trials of acupuncture in treating ASD, combining both modern medicine and traditional Chinese medicine.
FRONTIERS IN PSYCHIATRY
(2023)
Review
Biochemistry & Molecular Biology
Xi-Yan Liu, Tao Wen, Ze-Fan Wu, Nian-Hua Deng, Hui-Ting Liu, Zhong Ren, Wen-Hao Xiong, Zhi-Sheng Jiang
Summary: Abdominal aortic aneurysm (AAA) refers to the progressive dilation of the vascular wall below the aortic fissure, particularly below the renal artery. The molecular mechanism behind AAA is still unknown, but research has primarily focused on the vessel wall, considering inflammation and middle layer fracture as essential steps in AAA development. Perivascular adipose tissue also plays a significant role in the occurrence and progression of AAA.
CURRENT MEDICINAL CHEMISTRY
(2023)
Review
Endocrinology & Metabolism
Ke Peng, Wenjie Dong, Taimin Luo, Hui Tang, Wanlong Zhu, Yilan Huang, Xuping Yang
Summary: In recent decades, obesity has become a significant problem, causing a major burden on medical, social, and economic aspects. It not only directly affects the human body, but also leads to chronic diseases such as diabetes, cardiovascular diseases, nonalcoholic fatty liver disease, and mental illness. Weight loss remains one of the most effective strategies against obesity and related disorders. The link between intestinal microflora and metabolic health, specifically the role of butyrate, has been studied extensively, yet the mechanisms of its anti-obesity activity are not fully understood. This review aims to summarize current knowledge of butyrate and its effects on weight loss and obesity-related diseases, contributing to a better understanding of its role in obesity.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Neurosciences
Xinyi Yao, Haotian Liu, Jinyuan Si, Xiuyong Ding, Yu Zhao, Yun Zheng
Summary: Cochlear implants are successful sensory prostheses, but they come with various complications. Reimplantation as a solution to severe complications presents surgical risks and burden on patients and families. Therefore, establishing international consensus on cochlear reimplantation research is urgently needed for standardization and improvement.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Construction & Building Technology
Hongping Yuan, Wenbo Du, Zeyu Wang, Xiangnan Song
Summary: Developed countries such as Australia, Canada, the United States, and the United Kingdom have advantages in megaproject management research; complex views and theories are effectively used in studies, and future research will be global leadership, with megaprojects continuing to be designed and built, continuous in-depth research can promote innovation.
Review
Biotechnology & Applied Microbiology
Yue Yang, Geoffrey I. N. Waterhouse, Yilun Chen, Dongxiao Sun-Waterhouse, Dapeng Li
Summary: This review summarizes recent developments in microbial nanotechnology, providing insights into the mechanisms underlying the synthesis of microbial-assisted nanomaterials, the advantages of these materials in various applications, and the challenges that need to be overcome.
BIOTECHNOLOGY ADVANCES
(2022)
Review
Biochemistry & Molecular Biology
Qianming Chen, Yahui Wang, Jing Shuai
Summary: Research in stomatology is expanding globally, focusing on solving clinical issues and integrating materials science and tissue engineering to develop innovative materials and technologies for challenging clinical problems. The emergence of intelligent stomatology with AI, 5G technology, and big data applications is expected to improve clinical diagnosis and management models.
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B
(2023)
Review
Biochemistry & Molecular Biology
Chongjing Xia, Age Qiu, Meinan Wang, Taiguo Liu, Wanquan Chen, Xianming Chen
Summary: This review summarizes the research on the genomics of rust fungi, including findings on genome size and composition variations, pathogen virulence, and population dynamics. The genomics of rust fungi provides insights into their rapid evolution and host adaptation, and contributes to disease management.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Veterinary Sciences
Jingwen Cui, Wanrong Song, Yipeng Jin, Huihao Xu, Kai Fan, Degui Lin, Zhihui Hao, Jiahao Lin
Summary: Acupuncture, a conventional treatment method, is an essential part of Traditional Chinese Medicine. Recent studies have shown that acupuncture can activate local cell functions and regulate the release of biomolecules, ultimately affecting the neuroendocrine-immune network for holistic regulation. Efforts are ongoing to further understand the mechanisms of acupuncture through systems approaches like metabolomics and genomics.
VETERINARY SCIENCES
(2021)
Review
Chemistry, Analytical
Nediljko Kastelan, Igor Vujovic, Maja Krcum, Nur Assani
Summary: To keep up with global energy efficiency trends and emission reduction targets, adaptations of onshore and maritime power distribution systems are necessary, particularly in medium-voltage switchgear. The concept of digital switchgear, equipped with sensor technology and machine learning algorithms, enables efficient condition monitoring and predictive maintenance. This paper outlines the challenges, current research, and future directions in this field, emphasizing the potential of artificial intelligence for operational data interpretation and the need for standardized test procedures and data sets.
Review
Genetics & Heredity
Zhuang Li, Jun Lu
Summary: Osteoarthritis (OA) is a common joint disease with irreversible progression. CircRNAs play a vital role in various aspects of OA, including extracellular matrix metabolism, autophagy, apoptosis, chondrocyte proliferation, inflammation, oxidative stress, cartilage development, and chondrogenic differentiation. Although circRNAs have regulatory roles in OA and potential clinical value, further studies are needed.
FRONTIERS IN GENETICS
(2023)
Article
Medicine, Research & Experimental
Shiya Huang, Min Hu, Ernest Hung Yu Ng, Elisabet Stener-Victorin, Yanhua Zheng, Qidan Wen, Cong Wang, Maohua Lai, Juan Li, Xingcheng Gao, Xinhua Wang, Zhenxing Hu, Tian Xia, Rongkui Hu, Jianping Liu, Xiaohui Wen, Shuna Li, Kewei Quan, Xingyan Liang, Hongcai Shang, Hongxia Ma, Jie Qiao
Article
Endocrinology & Metabolism
Anna Benrick, Nicolas J. Pillon, Emma Nilsson, Eva Lindgren, Anna Krook, Charlotte Ling, Elisabet Stener-Victorin
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2020)
Article
Integrative & Complementary Medicine
Juan Li, Wanting Wu, Elisabet Stener-Victorin, Ernest Hung Yu Ng, Raymond Hang Wun Li, Meifang Li, Hua Liu, Maohua Lai, Yanbing Meng, Yanhua Zheng, Yang Xia, Hongxia Ma
ACUPUNCTURE IN MEDICINE
(2020)
Article
Psychiatry
Sanjiv Risal, Maria Manti, Haojiang Lu, Romina Fornes, Henrik Larsson, Anna Benrick, Qiaolin Deng, Carolyn E. Cesta, Mina A. Rosenqvist, Elisabet Stener-Victorin
Summary: This study found that daughters of women with PCOS have an increased risk of anxiety disorders, possibly transmitted transgenerationally through the female germline. Using a PCOS mouse model, researchers observed anxiety-like behavior in female offspring in the androgenized lineage and male offspring in both the androgenized and obese lineages. Additionally, dysregulated genes related to anxiety-like behavior were identified in the amygdala of female offspring in the androgenized lineage and male offspring in the obese lineage.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Biochemistry & Molecular Biology
Yanling Wu, Belen Chanclon, Peter Micallef, Elisabet Stener-Victorin, Ingrid Wernstedt Asterholm, Anna Benrick
Summary: The study demonstrates that elevated levels of adiponectin in utero can improve insulin sensitivity, reduce body weight and fat mass gain in adult offspring, and protect against PNA-induced visceral adiposity in the offspring.
Article
Obstetrics & Gynecology
X. Jiang, Q. Deng, E. Stener-Victorin
Summary: This study examined the genetic basis and causal relationship between polycystic ovary syndrome (PCOS) and a range of psychiatric disorders, finding no significant genetic correlation or causal relationship between them, despite some associations in certain contexts. While PCOS seems to be related to depression genetically, this effect may be mediated by BMI.
HUMAN REPRODUCTION
(2021)
Review
Endocrinology & Metabolism
Elisabet Stener-Victorin, Qiaolin Deng
Summary: Polycystic ovary syndrome (PCOS) is a major cause of female infertility worldwide, with high prevalence and economic burden. The etiology of PCOS involves genetic and developmental factors, with hyperandrogenism playing a key role. Current treatments are limited, highlighting the need for more effective preventative and targeted therapies.
NATURE REVIEWS ENDOCRINOLOGY
(2021)
Editorial Material
Biochemistry & Molecular Biology
Elisabet Stener-Victorin, Qiaolin Deng
Summary: A recent study has found that late gestation exposure to anti-Mullerian hormone can result in the transgenerational transmission of a PCOS-like phenotype in mice, with altered DNA methylation being the underlying mechanism. Epigenetics-based therapy has shown promise in reversing some PCOS-like traits in F-3 female mice.
TRENDS IN MOLECULAR MEDICINE
(2021)
Letter
Obstetrics & Gynecology
Hongxia Ma, Min Hu, Qidan Wen, Elisabet Stener-Victorin
HUMAN REPRODUCTION
(2022)
Article
Biochemistry & Molecular Biology
Man Mohan Shrestha, Sanne Wermelin, Elisabet Stener-Victorin, Ingrid Wernstedt Asterholm, Anna Benrick
Summary: Adiponectin deficiency affects fetal growth and placental function, particularly in obese individuals. Low levels of adiponectin lead to placental dysfunction and increased fetal triglyceride load, which could have long-term effects on the offspring's metabolism.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Endocrinology & Metabolism
Qianwen Liu, Bowen Tang, Zhaozhong Zhu, Peter Kraft, Qiaolin Deng, Elisabet Stener-Victorin, Xia Jiang
Summary: The genetic link between type 2 diabetes, glycaemic traits and PCOS was found, influenced by both biological pleiotropy and causal mediation, some of which is independent of BMI. The study highlights the importance of controlling fasting insulin levels to mitigate the risk of PCOS, as well as screening for and monitoring type 2 diabetes in all women with PCOS, irrespective of BMI.
Article
Biology
Yu Pei, Sanjiv Risal, Hong Jiang, Haojiang Lu, Eva Lindgren, Elisabet Stener-Victorin, Qiaolin Deng
Summary: Excessive androgen production and obesity play a key role in the development of polycystic ovary syndrome (PCOS). Various mouse models, including prenatal androgenized, peripubertal androgenized, overexpression of nerve growth factor in theca cells, and diet-induced maternal obesity, were used to study PCOS. Transcriptome analysis revealed differentially expressed genes in the hypothalamus, adipose tissue, ovary, and oocytes, with the ovaries and adipose tissues showing the most significant changes. The Ms4a6e gene, found in all mouse models and in women with PCOS, suggests a conserved disease function in PCOS.
COMMUNICATIONS BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Tina Ronn, Alexander Perfilyev, Josefine Jonsson, Karl-Fredrik Eriksson, Sine W. Jorgensen, Charlotte Brons, Linn Gillberg, Allan Vaag, Elisabet Stener-Victorin, Charlotte Ling
Summary: This study found an association between DNA methylation levels in adipose tissue and circulating lipid levels, and identified novel epigenetic changes associated with lipid levels. These findings provide insights into the relationship between dysregulation of circulating lipids and epigenetic mechanisms in adipose tissue, and have important implications for the study of metabolic syndrome.
HUMAN MOLECULAR GENETICS
(2023)
Review
Endocrinology & Metabolism
Meri Davitadze, Kashish Malhotra, Halimah Khalil, Meghnaa Hebbar, Chau Thien Tay, Aya Mousa, Helena PCOS SEva Team, Helena Teede, Leah Brennan, Elisabet Stener-Victorin, Punith Kempegowda
Summary: This systematic review and meta-analysis compared body image concerns among women with and without polycystic ovary syndrome (PCOS). The results showed that women with PCOS reported higher dissatisfaction with appearance evaluation and appearance orientation. They also had higher dissatisfaction with overweight preoccupation, lower body area satisfaction, and body weight classification compared to women without PCOS. These findings highlight the importance of addressing body image concerns in the clinical care of PCOS.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2023)
Review
Endocrinology & Metabolism
Elisabet Stener-Victorin
Summary: Polycystic ovary syndrome (PCOS) is a complex disease affecting women of reproductive age, with unclear etiology. Animal models provide an important approach to study the pathophysiology, genetics, prevention, and treatment of PCOS.
