期刊
NANOSCALE
卷 7, 期 16, 页码 7178-7183出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4nr07443b
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- Joint Center of Excellence in Integrated Nano-Systems (JCIN) at King Abdul-Aziz City for Science and Technology (KACST) [34-941]
- Joint Center of Excellence in Integrated Nano-Systems (JCIN) at Northwestern University (NU) [34-941]
Gating of mesoporous silica nanoparticles (MSNs) with the stimuli-responsive poly(beta-amino ester) has been achieved. This hybrid nanocarrier releases doxorubicin (DOX) under acidic conditions or in the presence of porcine liver esterase. The DOX loaded poly(beta-amino ester)-capped MSNs reduce cell viability when tested on MDA-MB-231 human breast cancer cells.
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