Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer

Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes

(2015) Philipp M. Klein et al.   JOURNAL OF CONTROLLED RELEASE

Dual-Targeted Polyplexes Based on Sequence-Defined Peptide-PEG-Oligoamino Amides

(2015) Petra Kos et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Correlation of Length of Linear Oligo(ethanamino) Amides with Gene Transfer and Cytotoxicity

(2014) Claudia Scholz et al.   ChemMedChem

Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers

(2014) Can Yang Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Targeting of follicle stimulating hormone peptide-conjugated dendrimers to ovarian cancer cells

(2014) Dimple A. Modi et al.   Nanoscale

Untying a nanoscale knotted polymer structure to linear chains for efficient gene delivery in vitro and to the brain

(2014) B. Newland et al.   Nanoscale

Multifunctional pH-sensitive polymeric nanoparticles for theranostics evaluated experimentally in cancer

(2014) Yongjun Liu et al.   Nanoscale

A Systematic Analysis of Peptide Linker Length and Liposomal Polyethylene Glycol Coating on Cellular Uptake of Peptide-Targeted Liposomes

(2013) Jared F. Stefanick et al.   ACS Nano

Peptide Dendrimer/Lipid Hybrid Systems Are Efficient DNA Transfection Reagents: Structure–Activity Relationships Highlight the Role of Charge Distribution Across Dendrimer Generations

(2013) Albert Kwok et al.   ACS Nano

Balancing Cationic and Hydrophobic Content of PEGylated siRNA Polyplexes Enhances Endosome Escape, Stability, Blood Circulation Time, and Bioactivity in Vivo

(2013) Christopher E. Nelson et al.   ACS Nano

Bioreducible Polycations as Shuttles for Therapeutic Nucleic Acid and Protein Transfection

(2013) Philipp M. Klein et al.   ANTIOXIDANTS & REDOX SIGNALING

Surface-Modified HK:siRNA Nanoplexes with Enhanced Pharmacokinetics and Tumor Growth Inhibition

(2013) Szu-Ting Chou et al.   BIOMACROMOLECULES

FGFR-targeted gene delivery mediated by supramolecular assembly between β-cyclodextrin-crosslinked PEI and redox-sensitive PEG

(2013) Yuan Ping et al.   BIOMATERIALS

Targeting hepatocyte growth factor receptor (Met) positive tumor cells using internalizing nanobody-decorated albumin nanoparticles

(2013) Raimond Heukers et al.   BIOMATERIALS

Preclinical Efficacy of the Anti-Hepatocyte Growth Factor Antibody Ficlatuzumab in a Mouse Brain Orthotopic Glioma Model Evaluated by Bioluminescence, PET, and MRI

(2013) E. S. Mittra et al.   CLINICAL CANCER RESEARCH

PEG length and chemical linkage controls polyacridine peptide DNA polyplex pharmacokinetics, biodistribution, metabolic stability and in vivo gene expression

(2013) Sanjib Khargharia et al.   JOURNAL OF CONTROLLED RELEASE

Safety of the intravenous administration of neurotensin-polyplex nanoparticles in BALB/c mice

(2013) Maria E. Hernandez et al.   Nanomedicine-Nanotechnology Biology and Medicine

Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes

(2013) Ulrich Lächelt et al.   Nanomedicine-Nanotechnology Biology and Medicine

Copolymer of poly(ethylene glycol) and poly(l-lysine) grafting polyethylenimine through a reducible disulfide linkage for siRNA delivery

(2013) Jingguo Li et al.   Nanoscale

A Human Anti-c-Met Fab Fragment Conjugated with Doxorubicin as Targeted Chemotherapy for Hepatocellular Carcinoma

(2013) Ximin Chen et al.   PLoS One

Comparative study of guanidine-based and lysine-based brush copolymers for plasmid delivery

(2013) Peter M. Carlson et al.   Biomaterials Science

Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery

(2012) Christian Dohmen et al.   ACS Nano

Hepatocyte Growth Factor and Its Receptor Signalling Complex as Targets in Cancer Therapy

(2012) Tracey Martin et al.   Anti-Cancer Agents in Medicinal Chemistry

CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma

(2012) Lina Wang et al.   BIOMATERIALS

Stabilizing effect of tyrosine trimers on pDNA and siRNA polyplexes

(2012) Christina Troiber et al.   BIOMATERIALS

Differential effects of a soluble or immobilized VEGFR-binding peptide

(2012) Justin T. Koepsel et al.   Integrative Biology

Sequence-defined four-arm oligo(ethanamino)amides for pDNA and siRNA delivery: Impact of building blocks on efficacy

(2012) Eveline E. Salcher et al.   JOURNAL OF CONTROLLED RELEASE

Nanobodies Targeting the Hepatocyte Growth Factor: Potential New Drugs for Molecular Cancer Therapy

(2012) M. J. W. D. Vosjan et al.   MOLECULAR CANCER THERAPEUTICS

Tuning Nanoparticle Uptake: Live-Cell Imaging Reveals Two Distinct Endocytosis Mechanisms Mediated by Natural and Artificial EGFR Targeting Ligand

(2012) Frauke M. Mickler et al.   NANO LETTERS

Solid-phase-assisted synthesis of targeting peptide–PEG–oligo(ethane amino)amides for receptor-mediated gene delivery

(2012) Irene Martin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Solid-Phase Synthesis of Sequence-Defined T-, i-, and U-Shape Polymers for pDNA and siRNA Delivery

(2011) David Schaffert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single chain anti-c-Met antibody conjugated nanoparticles for in vivo tumor-targeted imaging and drug delivery

(2011) Ruei-Min Lu et al.   BIOMATERIALS

MET Signaling Pathway: A Rational Target for Cancer Therapy

(2011) Leonard J. Appleman   JOURNAL OF CLINICAL ONCOLOGY

Odd–Even Effect of Repeating Aminoethylene Units in the Side Chain of N-Substituted Polyaspartamides on Gene Transfection Profiles

(2011) Hirokuni Uchida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel Fmoc-Polyamino Acids for Solid-Phase Synthesis of Defined Polyamidoamines

(2011) David Schaffert et al.   ORGANIC LETTERS

Precision Polymers: Monodisperse, Monomer-Sequence-Defined Segments to Target Future Demands of Polymers in Medicine

(2009) L. Hartmann et al.   ADVANCED MATERIALS

In VivoImaging of Mesenchymal−Epithelial Transition Factor (c-Met) Expression using an Optical Imaging System

(2009) Eun-Mi Kim et al.   BIOCONJUGATE CHEMISTRY

Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers

(2009) Patrick Midoux et al.   BRITISH JOURNAL OF PHARMACOLOGY

Synthesis and Biological Evaluation of a Bioresponsive and Endosomolytic siRNA−Polymer Conjugate

(2009) Martin Meyer et al.   MOLECULAR PHARMACEUTICS

Reducible Poly(oligo-D-arginine) for Enhanced Gene Expression in Mouse Lung by Intratracheal Injection

(2009) Young-Wook Won et al.   MOLECULAR THERAPY

Characterization, biodistribution and small-animal SPECT of I-125-labeled c-Met binding peptide in mice bearing c-Met receptor tyrosine kinase-positive tumor xenografts

(2009) Eun-Mi Kim et al.   NUCLEAR MEDICINE AND BIOLOGY

General Structure–Activity Relationship for Poly(glycoamidoamine)s: The Effect of Amine Density on Cytotoxicity and DNA Delivery Efficiency

(2008) Chen-Chang Lee et al.   BIOCONJUGATE CHEMISTRY

Cellular Uptake and Intracellular Pathways of PLL-g-PEG-DNA Nanoparticles

(2008) Tessa Lühmann et al.   BIOCONJUGATE CHEMISTRY

Tailor-Made Poly(amidoamine)s for Controlled Complexation and Condensation of DNA

(2008) Laura Hartmann et al.   CHEMISTRY-A EUROPEAN JOURNAL

A proline-rich peptide improves cell transfection of solid lipid nanoparticle-based non-viral vectors

(2008) A. del Pozo-Rodríguez et al.   JOURNAL OF CONTROLLED RELEASE

Bioreducible poly(amido amine)s with oligoamine side chains: Synthesis, characterization, and structural effects on gene delivery

(2007) Chao Lin et al.   JOURNAL OF CONTROLLED RELEASE