Article
Biochemistry & Molecular Biology
Hong Yu Yang, Jia Meng Du, Moon-Sun Jang, Xin Wang Mo, Xin Shun Sun, Doo Sung Lee, Jung Hee Lee, Yan Fu
Summary: EPNGs were successfully fabricated for CD44-targeted transport of cytochrome c through UV-triggered chemical cross-linking, showing stable and high protein encapsulation efficiency in blood circulation and rapid release in targeted tumor cells.
Article
Chemistry, Multidisciplinary
Won Jung Kim, Eu Hyun Lee, Yong-Jin Kwon, Sang-Kyu Ye, Kyu Oh Kim
Summary: An amphipathic PAA-POSS@DOX drug delivery system that is sensitive to pH changes in the cancer microenvironment has been developed using a nanoparticle based on inorganic polyhedral oligomeric silsesquioxane (POSS). This system has high loading efficiency and can quickly release the drug to the target area, as confirmed by cell death in the MDA-MB-231 breast cancer line.
Article
Biotechnology & Applied Microbiology
Shudi Yang, Weiliang Chen, Wei Li, Jingcheng Song, Yue Gao, Wenhui Si, Xiaoping Li, Baowei Cui, Tongtong Yu
Summary: The study prepared CD44-targeted pH-responsive micelles for efficient delivery and release of doxorubicin based on the overexpressed CD44 receptor and mild acidic microenvironment of tumor cells. These micelles exhibited enhanced cellular uptake and cytotoxicity, as well as excellent tumor-targeting effects in vitro and improved anti-tumor effects with reduced side effects in vivo.
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Lingli Jin, Yanwen Xu, Fengjiao Chen, Dingle Yu, Hongze Liang, Zhenjiang Liang, Ziyu Liu, Haiyan Li, Junying Liu, Hui Tan, Lingling Zhao
Summary: A mitochondria-targeted and pH-triggered charge-convertible polymeric micellar system was developed for doxorubicin delivery and targeted anticancer therapy. It showed sustained drug release and enhanced cellular uptake, accumulation in mitochondria, and efficient release of doxorubicin in tumor cells.
MATERIALS & DESIGN
(2022)
Article
Chemistry, Multidisciplinary
Yingshu Guo, Xiuping Cao, Shusheng Zhang
Summary: The research introduces a complex coated with cancer cell membrane for targeted drug delivery and enhanced therapy.
CHEMICAL COMMUNICATIONS
(2021)
Article
Materials Science, Biomaterials
Jianhong Liao, Haisheng Peng, Can Liu, Dan Li, Yihua Yin, Bo Lu, Hua Zheng, Qun Wang
Summary: A novel nanodrug delivery system based on PDPP block copolymers was developed to enhance in vitro cellular uptake and anticancer efficacy. The charge-reversal of micelles from negative to positive at pH 6.5 significantly enhanced cellular uptake and anticancer efficacy.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Pharmacology & Pharmacy
Muhammad Abdur Rahim, Asadullah Madni, Nayab Tahir, Nasrullah Jan, Hassan Shah, Safiullah Khan, Riaz Ullah, Ahmed Bari, Muhammad Sohaib Khan
Summary: This study aimed to develop Dox loaded mild temperature responsive liposomes (MTLs) with optimal size, stability, and Dox entrapment. The optimized MTLs showed rapid in vitro Dox release and improved anticancer efficacy, indicating their potential as a safe and effective therapeutic strategy against hepatocellular carcinoma.
Article
Engineering, Biomedical
Fangjun Liu, Dun Wang, Miao Zhang, Liwei Ma, Cui-Yun Yu, Hua Wei
Summary: The synthesis of PF-based theranostic amphiphilic copolymers with high drug loading efficiency and tumor microenvironment-specific responsiveness for enhanced cancer therapy has been rarely reported. In this study, enzyme-responsive theranostic amphiphilic bottlebrush copolymers were successfully prepared, showing high drug loading efficiency and tumor microenvironment-specific responsiveness. The study developed a universal strategy for the construction of multifunctional polymeric vehicles based on PF and degradable polypeptide, and emphasized the better stability of micelles endowed by the branched hydrophilic brushes.
ACTA BIOMATERIALIA
(2022)
Article
Materials Science, Biomaterials
Dongxu Zhou, Zhixiong Fei, Lunqiang Jin, Peng Zhou, Chenxi Li, Xiaoling Liu, Changsheng Zhao
Summary: Multi stimuli-responsive polymersomes designed via self-assembly can serve as smart drug carriers, enabling separate control over the release of multiple drug pairs. They show promising potential for tumor combination chemotherapy by taking effect for a relatively longer period in a simulated tumor microenvironment.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Chemistry, Applied
Min Li, Yinan Zhao, Jiao Sun, Huiying Chen, Zhanbiao Liu, Kexin Lin, Pengfei Ma, Wenjun Zhang, Yuhong Zhen, Shufen Zhang, Shubiao Zhang
Summary: Polymer-based prodrug nanocarriers with tumor-targeting and controlled-release properties are highly desirable for improving cancer treatment. Hyaluronic acid (HA), known for its excellent biocompatibility and targeting ability for CD44, has been suggested as a carrier for delivering drugs with poor solubility and high toxicity. In this study, podophyllotoxin (PPT) was conjugated to HA through ester and disulfide linkages to create a pH and reduction-responsive prodrug (HA-S-S-PPT). Micelles self-assembled from HA-S-S-PPT efficiently accumulated at the tumor site due to HA receptor-mediated endocytosis. These micelles exhibited 33.1% higher cumulative release compared to HA-NH-CO-PPT micelles, which were only sensitive to pH. HA-S-S-PPT micelles demonstrated excellent antitumor activity in vivo, with a tumor inhibition rate of 92%, significantly higher than that of HA-NH-CO-PPT micelles (65%), and minimal systemic toxicity. This controllable-targeting nanoparticle system presents a potential platform for the clinical application of PPT.
CARBOHYDRATE POLYMERS
(2022)
Article
Biophysics
Hualu Lai, Xin Ding, Junxian Ye, Jie Deng, Shengmiao Cui
Summary: In this study, amphiphilic HA-ADH-CUR conjugates were synthesized and self-assembled to form HA@CUR NPs which exhibited pH-responsive drug release behavior. The nanoparticles could efficiently internalize by cancer cells via CD44 receptor mediated endocytosis and release CUR for chemotherapy, showing promising potential for enhanced cancer therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Ziqiang Zhou, Yanfang Wang, Ping Hu
Summary: A new approach based on FRET mechanism was reported for monitoring drug release and inflammatory reactions in vitro and in vivo. Mixed micelles containing a fluorescent donor and its quencher were prepared and their stability and responsiveness towards oxidants were tested. The micelles were able to restore fluorescence and visualize inflammatory cells and reactions.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Oncology
Ran Li, Ruifang Gao, Yingjiao Zhao, Fang Zhang, Xiangyu Wang, Bing Li, Lu Wang, Lixin Ma, Jie Du
Summary: Oral squamous cell carcinoma (OSCC) is the most common type of cancer in the oral and maxillofacial regions, but its treatment remains challenging. In this study, a GRPR-targeted nano-graphene oxide (NGO) nanoprobe drug delivery system was developed to improve the treatment of OSCC.
FRONTIERS IN ONCOLOGY
(2022)
Article
Pharmacology & Pharmacy
Qiyi Feng, Junhuai Xu, Xinyi Liu, Haibo Wang, Junjie Xiong, Kai Xiao
Summary: Stimuli-responsive nanotherapeutics based on pH-responsive micelles showed great potential in precision oncology. The micelles efficiently encapsulated and released anti-cancer drugs, leading to cell death in cancer cells. They also prolonged blood circulation, reduced cardiac toxicity, and selectively delivered drugs to tumor tissues. Overall, these micelles significantly improved anti-tumor efficacy and reduced systemic toxicity, indicating their translational potential in precise drug delivery for cancer treatment.
Article
Polymer Science
Mahmood Barani, Mohammad Reza Hajinezhad, Saman Sargazi, Mahira Zeeshan, Abbas Rahdar, Sadanand Pandey, Mehrdad Khatami, Farshid Zargari
Summary: In this study, pH-responsive niosomal methotrexate modified with ergosterol was prepared for potential anticancer application. The formulation showed pH-responsive behavior in two different pHs and exhibited strong cytotoxic effects on MCF7 cells with lower toxicity in normal cells. The in-silico evaluation demonstrated the strong hydrogen bonding between MTX and Span 60 in the niosomal compartments, suggesting a promising approach for future cancer therapy.
Article
Engineering, Biomedical
Zujian Feng, Yumin Zhang, Chunfang Yang, Xiang Liu, Yini Huangfu, Chuangnian Zhang, Pingsheng Huang, Anjie Dong, Jinjian Liu, Jianfeng Liu, Deling Kong, Weiwei Wang
Summary: A glycopeptide hydrogel inspired by extracellular matrix (ECM) has been designed to accelerate wound healing in radiation-induced skin injury (RSI) by modulating chronic inflammation. The hydrogel replicates ECM components and structure, scavenges reactive oxygen species (ROS), and polarizes macrophages to reduce inflammation. In mouse models, the hydrogel significantly reduces hyperplasia, promotes regeneration and angiogenesis, and decreases proinflammatory cytokine expression, making it superior to current treatment options.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Engineering, Environmental
Yun Li, Xiaoyao Cai, Zhilong Wang, Yu Han, Chunhua Ren, Lijun Yang, Zhongyan Wang, Ganen Mu, Haixue Jia, Jianfeng Liu, Jinjian Liu, Cuihong Yang
Summary: Inspired by protein-metal ion regulation, researchers have been studying the role of metal coordination in peptide folding and assembly. A bio-inspired peptide derivative (Supra GHK) was developed, which self-assembled into a supramolecular metallopeptide hydrogel (Supra GHK-Cu) upon the addition of Cu2+. Cu2+ induced allosteric effects on the folded structure of Supra GHK through chelation. Supra GHK-Cu exhibited resistance to protease degradation, accelerated wound healing, and showed promise for applications in various biomedical fields.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Chemistry, Physical
Jingying Shi, Xuefei Zhao, Can Li
Summary: Surface passivation engineering is a crucial approach to enhance the performance of photoelectrodes in photoelectrochemical (PEC) water splitting. This review summarizes various passivation materials and their preparation methods, characterizations by PEC measurements and related spectral technologies. The distinct features of the passivation effect, separate from other modifications such as cocatalyst decoration, are highlighted. Significant progress in combining surface passivation engineering with other interfacial modification strategies for the rational design of photoelectrodes is demonstrated. Ideas for future research on surface passivation modification to improve the performance of photoelectrodes are also proposed.
Article
Chemistry, Multidisciplinary
Lijun Yang, Dianyu Wang, Haixue Jia, Cuihong Yang, Yumin Zhang, Hui Li, Jinjian Liu, Jianfeng Liu
Summary: Tumor cells use metabolic reprogramming to create an immunosuppressive tumor microenvironment (TME) and evade the immune system. This study develops a tumor-specific peroxynitrite nanogenerator that disrupts metabolic homeostasis in melanoma cells. The produced peroxynitrite induces a decrease in metabolites in the tricarboxylic acid cycle and reduces lactate production. Mechanistically, peroxynitrite impairs glucose metabolism by affecting the activity of glyceraldehyde-3-phosphate dehydrogenase. These metabolic alterations reverse the immunosuppressive TME and promote antitumor immune responses. When combined with anti-PD-L1, the nanogenerator inhibits both primary and metastatic melanomas without causing toxicity. This research provides a new strategy for enhancing immunotherapy sensitivity.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Qian Wang, Hongmei Cao, Xiaoxue Hou, Dianyu Wang, Zhilong Wang, Yue Shang, Shuqin Zhang, Jinjian Liu, Chunhua Ren, Jianfeng Liu
Summary: A surface-induced self-assembly system (CA-Pt) is developed to overcome hypoxic cancer stem cell-mediated radioresistance by deep penetration, amplified CAIX inhibition, and enhanced cellular uptake. It effectively relieves the hypoxic and acidic microenvironment, promotes the differentiation of hypoxic CSCs, and enhances the DNA damage induced by radiotherapy. This study provides a universal treatment strategy for overcoming tumor radioresistance.
ADVANCED MATERIALS
(2023)
Article
Engineering, Biomedical
Yusen Hao, Hui Li, Jiajun Guo, Dan Wang, Jiamin Zhang, Jinjian Liu, Cuihong Yang, Yumin Zhang, Guoliang Li, Jianfeng Liu
Summary: Radiotherapy is an important cancer treatment method, but it can cause adverse reactions and injuries to the skin. This study designed an antioxidant heparin-mimetic peptide hydrogel (K16) for repairing radiation-induced skin injuries (RISI). The K16 hydrogel can scavenge excess reactive oxygen species (ROS), prevent radiation damage to DNA, promote cell proliferation, migration, and angiogenesis, and eliminate inflammation at the wound site. In vivo experiments demonstrated that the K16 hydrogel inhibits wound degradation, reduces inflammation, and promotes wound healing. Therefore, the K16 hydrogel has great potential for application in repairing radiation-induced skin injuries.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Engineering, Biomedical
Hongjing Luo, Hongmei Cao, Haixue Jia, Yuna Shang, Jinjian Liu, Han Gui, Cuihong Yang, Chunhua Ren, Zhongyan Wang, Jianfeng Liu
Summary: Radiotherapy can remodel the tumor microenvironment by inducing immunogenic cell death and inflammation, but it is not effective in generating a systemic antitumor immune response. This study presents a novel strategy to create in situ peptide-based nanovaccines using enzyme-induced self-assembly, in combination with immunogenic cell death. The nanovaccine enhances antigen accumulation in the lymph nodes and cross-presentation by antigen-presenting cells, and promotes the repolarization of macrophages and reduces regulatory T cells and myeloid-derived suppressor cells. The combination of nanovaccines and radiotherapy significantly improves the therapeutic effect on tumors, providing a promising strategy for tumor radioimmunotherapy.
ADVANCED HEALTHCARE MATERIALS
(2023)
Review
Endocrinology & Metabolism
Cunqing Yang, Xuefei Zhao, Xuedong An, Yuehong Zhang, Wenjie Sun, Yuqing Zhang, Yingying Duan, Xiaomin Kang, Yuting Sun, Linlin Jiang, Fengmei Lian
Summary: Diabetic peripheral neuropathy is a chronic metabolic disease that seriously affects patients' quality of life and can lead to amputation and neuropathic pain. Current treatment options only address symptoms and do not reverse nerve damage. Understanding the underlying mechanisms is crucial for prevention and the development of new therapies.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Endocrinology & Metabolism
Xuefei Zhao, Xuedong An, Cunqing Yang, Wenjie Sun, Hangyu Ji, Fengmei Lian
Summary: Insulin resistance (IR) is crucial in metabolism-related diseases and provides a basis for understanding chronic diseases. This study reviewed the causes, mechanisms, and treatments of IR. Various factors including genetics, obesity, and disease lead to abnormalities in the insulin signaling pathway and development of IR. Therapeutic strategies include exercise, dietary changes, chemotherapy, and traditional Chinese medicine treatments. Further research is needed to define biomarkers and explore targeted drug treatments for IR to improve patients' quality of life.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Zhongyan Wang, Yuna Shang, Hongjing Luo, Cuihong Yang, Zhimou Yang, Chunhua Ren, Jianfeng Liu
Summary: This study presents a novel strategy of achieving higher hierarchical structures through cooperative self-assembly of hydrophobic tripeptides with reverse sequences, showing a low-to-high hierarchical structure transformation. The cooperation between different sequences also allows different morphological transitions, promoting a more compact molecular arrangement by creating more hydrogen bond interactions and in-register π-π stacking in the anti-parallel β-sheet conformation. This work provides a handy approach for controlled hierarchical assembly and the development of various functional bionanomaterials.
Article
Chemistry, Multidisciplinary
Shushuang Sun, Yaming Zhu, Zishuo Gu, Hongyu Chu, Chaoshuai Hu, Lijuan Gao, Xuefei Zhao
Summary: In this study, bamboo fiber activated carbon (BAC) with high specific surface area and pore volume was prepared through the optimized process using response surface method. Characterization methods were used to analyze the micro-structure of BAC, which showed that BAC maintained the original pores of the bamboo fiber. The adsorption capacity of BAC for crystal violet in simulated wastewater reached a removal rate of 99.96%, and the adsorption process conformed to the pseudo-second-order kinetic model and Langmuir adsorption isotherm model. BAC has great application prospects in dye wastewater treatment.
Article
Chemistry, Multidisciplinary
Qiannan Cao, Cuihong Yang, Yuan Yao, Bin Li, Jinjian Liu, Zhipeng Cao, Jianfeng Liu, Meng Xiao
Summary: This study presents the development of a convertible bismuth-based agent for tumour-selective theranostic functionalities, inspired by the metabolic pathways of exogenous sodium selenite. The agent converts from bismuth selenite to bismuth selenide specifically in tumour tissues, enabling excellent multidimensional imaging-guided therapy.
MATERIALS HORIZONS
(2023)
Article
Chemistry, Multidisciplinary
Qian Wang, Hongmei Cao, Xiaoxue Hou, Dianyu Wang, Zhilong Wang, Yue Shang, Shuqin Zhang, Jinjian Liu, Chunhua Ren, Jianfeng Liu
Summary: This study reports a CAIX-targeted induced in situ self-assembly system on the surface of hypoxic cancer stem-like cells (CSCs), which relieves the hypoxic and acidic microenvironment and promotes CSC differentiation to overcome tumor radiotherapy resistance. The constructed peptide-based drug delivery system exhibits deep penetration, amplified CAIX inhibition, and enhanced cellular uptake, showing potential as a universal treatment strategy for overcoming tumor radioresistance.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Laetitia Bardet, Herve Roussel, Stefano Saroglia, Masoud Akbari, David Munoz-Rojas, Carmen Jimenez, Aurore Denneulin, Daniel Bellet
Summary: The thermal instability of silver nanowires leads to increased electrical resistance in AgNW networks. Understanding the relationship between structural and electrical properties of AgNW networks is crucial for their integration as transparent electrodes in flexible optoelectronics. In situ X-ray diffraction measurements were used to study the crystallographic evolution of Ag-specific Bragg peaks during thermal ramping, revealing differences in thermal and structural transitions between bare and SnO2-coated AgNW networks.
Article
Chemistry, Multidisciplinary
Nathalia Cancino-Fuentes, Arnau Manasanch, Joana Covelo, Alex Suarez-Perez, Enrique Fernandez, Stratis Matsoukis, Christoph Guger, Xavi Illa, Anton Guimera-Brunet, Maria V. Sanchez-Vives
Summary: This study provides a comprehensive characterization of graphene-based solution-gated field-effect transistors (gSGFETs) for brain recordings, highlighting their potential clinical applications.
Article
Chemistry, Multidisciplinary
Sikandar Aftab, Hailiang Liu, Dhanasekaran Vikraman, Sajjad Hussain, Jungwon Kang, Abdullah A. Al-Kahtani
Summary: This study examines the effects of hybrid nanoparticles made of NiO@rGO and NiO@CNT on the active layers of polymer solar cells and X-ray photodetectors. The findings show that these hybrid nanoparticles can enhance the charge carrier capacities and exciton dissociation properties of the active layers. Among the tested configurations, the NiO@CNT device demonstrates superior performance in converting sunlight into electricity, and achieves the best sensitivity for X-ray detection.
Article
Chemistry, Multidisciplinary
Hyo Jung Shin, Seung Gyu Choi, Fengrui Qu, Min-Hee Yi, Choong-Hyun Lee, Sang Ryong Kim, Hyeong-Geug Kim, Jaewon Beom, Yoonyoung Yi, Do Kyung Kim, Eun-Hye Joe, Hee-Jung Song, Yonghyun Kim, Dong Woon Kim
Summary: This study investigates the role of SOX9 in reactive astrocytes following ischemic brain damage using a PLGA nanoparticle plasmid delivery system. The results demonstrate that PLGA nanoparticles can reduce ischemia-induced neurological deficits and infarct volume, providing a potential opportunity for stroke treatment.
Article
Chemistry, Multidisciplinary
Anurag Chaudhury, Koushik Debnath, Nikhil R. Jana, Jaydeep K. Basu
Summary: The study investigates the interaction between nanoparticles and cell membranes, and identifies key parameters, including charge, crowding, and membrane fluidity, that determine the adsorbed concentration and unbinding transition of nanoparticles.
Article
Chemistry, Multidisciplinary
Sina Sadeghi, Fazel Bateni, Taekhoon Kim, Dae Yong Son, Jeffrey A. Bennett, Negin Orouji, Venkat S. Punati, Christine Stark, Teagan D. Cerra, Rami Awad, Fernando Delgado-Licona, Jinge Xu, Nikolai Mukhin, Hannah Dickerson, Kristofer G. Reyes, Milad Abolhasani
Summary: In this study, an autonomous approach for the development of lead-free metal halide perovskite nanocrystals is presented, which integrates a modular microfluidic platform with machine learning-assisted synthesis modeling. This approach enables rapid and optimized synthesis of copper-based lead-free nanocrystals.
Article
Chemistry, Multidisciplinary
Zahir Abbas, Nissar Hussain, Surender Kumar, Shaikh M. Mobin
Summary: The rational construction of free-standing and flexible electrodes for electrochemical energy storage devices is an emerging research focus. In this study, a redox-active metal-organic framework (MOF) was prepared on carbon nanofibers using an in situ approach, resulting in a flexible electrode with high redox-active behavior and unique properties such as high flexibility and lightweight. The prepared electrode showed excellent cyclic retention and rate capability in supercapacitor applications. Additionally, it could be used as a freestanding electrode in flexible devices at different bending angles.
Article
Chemistry, Multidisciplinary
Lishan Zhang, Xiaoting Zhang, Hui Ran, Ze Chen, Yicheng Ye, Jiamiao Jiang, Ziwei Hu, Miral Azechi, Fei Peng, Hao Tian, Zhili Xu, Yingfeng Tu
Summary: Photodynamic therapy (PDT) is a promising local treatment modality in cancer therapy, but its therapeutic efficacy is restricted by ineffective delivery of photosensitizers and tumor hypoxia. In this study, a phototactic Chlorella-based near-infrared (NIR) driven green affording-oxygen microrobot system was developed for enhanced PDT. The system exhibited desirable phototaxis and continuous oxygen generation, leading to the inhibition of tumor growth in mice. This study demonstrates the potential of using a light-driven green affording-oxygen microrobot to enhance photodynamic therapy.
Article
Chemistry, Multidisciplinary
Yujin Li, Jing Xu, Xinqi Luo, Futing Wang, Zhong Dong, Ke-Jing Huang, Chengjie Hu, Mengyi Hou, Ren Cai
Summary: In this study, hollow heterostructured materials were constructed using an innovative template-engaged method as cathodes for zinc-ion batteries. The materials exhibited fast Zn2+ transport channels, improved electrical conductivity, and controlled volume expansion during cycling. The designed structure allowed for an admirable reversible capacity and high coulombic efficiency.
Article
Chemistry, Multidisciplinary
Paritosh Mahato, Shashi Shekhar, Rahul Yadav, Saptarshi Mukherjee
Summary: This study comprehensively elucidates the role of the core and electrostatic surface of metal nanoclusters in catalytic reduction reactions. The electrostatic surface dramatically modulates the reactivity of metal nanoclusters.
Article
Chemistry, Multidisciplinary
Pei Liu, Mengdi Liang, Zhengwei Liu, Haiyu Long, Han Cheng, Jiahe Su, Zhongbiao Tan, Xuewen He, Min Sun, Xiangqian Li, Shuai He
Summary: This study demonstrates a simple and environmentally-friendly method for the synthesis of zinc oxide nanozymes (ZnO NZs) using wasted hop extract (WHE). The WHE-ZnO NZs exhibit exceptional peroxidase-like activity and serve as effective catalysts for the oxidation of 3,3,5,5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). In addition, a straightforward colorimetric technique for detecting both H2O2 and glucose was developed using the WHE-ZnO NZs as peroxidase-like catalysts.
Article
Chemistry, Multidisciplinary
Hyunkyu Oh, Young Jun Lee, Eun Ji Kim, Jinseok Park, Hee-Eun Kim, Hyunsoo Lee, Hyunjoo Lee, Bumjoon J. Kim
Summary: Mesoporous carbon particles have unique structural properties that make them suitable as support materials for catalytic applications. This study investigates the impact of channel nanostructures on the catalytic activity of porous carbon particles (PCPs) by fabricating PCPs with controlled channel exposure on the carbon surface. The results show that PCPs with highly open channel nanostructures exhibit significantly higher catalytic activity compared to those with closed channel nanostructures.
Article
Chemistry, Multidisciplinary
Yunjie Lu, Zhaohui Li, Zewei Li, Shihao Zhou, Ning Zhang, Jianming Zhang, Lu Zong
Summary: A tough, long-lasting adhesive and highly conductive nanocomposite hydrogel (PACPH) was fabricated via the synergy of interfacial entanglement and adhesion group densification. PACPH possesses excellent mechanical properties, interfacial adhesion strength, and conductivity, making it a promising material for long-term monitoring of human activities and electrocardiogram signals.
Article
Chemistry, Multidisciplinary
Zichao Wei, Audrey Vandergriff, Chung-Hao Liu, Maham Liaqat, Mu-Ping Nieh, Yu Lei, Jie He
Summary: We have developed a simple method to prepare polymer-grafted plasmonic metal nanoparticles with pH-responsive surface-enhanced Raman scattering. By using pH-responsive polymers as ligands, the aggregation of nanoparticles can be controlled, leading to enhanced SERS. The pH-responsive polymer-grafted nanoparticles show high reproducibility and sensitivity in solution, providing a novel approach for SERS without the need for sample pre-concentration.
Article
Chemistry, Multidisciplinary
Melis Ozge Alas Colak, Ahmet Gungor, Merve Buldu Akturk, Emre Erdem, Rukan Genc
Summary: This research investigates the effect of functionalizing carbon dots with hydroxyl polymers on their performance as electrode materials in a supercapacitor. The results show that the functionalized carbon dots exhibit excellent electrochemical performance and improved stability.
