期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 62, 期 36, 页码 9024-9034出版社
AMER CHEMICAL SOC
DOI: 10.1021/jf502214x
关键词
notoginseng; ginsenosides; LC-MS; metabolomics; root
资金
- Macao Science and Technology Development Fund
- Macau Special Administrative Region [066/2011/A3]
- National Institutes of Health [AT005522-03]
Although both rhizome and root of Panax notoginseng are officially utilized as notoginseng in Chinese Pharmacopoeia, individual parts of the root were differently used in practice. To provide chemical evidence for the differentiated usage, quantitative comparison and metabolite profiling of different portions derived from the whole root, as well as commercial samples, were carried out, showing an overall higher content of saponins in rhizome, followed by main root, branch root, and fibrous root. Ginsenoside Rb-2 was proposed as a potential marker with a content of 0.5 mg/g as a threshold value for differentiating rhizome from other parts. Multivariate analysis of the metabolite profile further suggested 32 saponins as potential markers for the discrimination of different parts of notoginseng. Collectively, the study provided comprehensive chemical evidence for the distinct usage of different parts of notoginseng and, hence, is of great importance for the rational application and exploitation of individual parts of notoginseng.
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