Article
Chemistry, Applied
Aisha M. A. Ahmed, Khalid A. Khalid
Summary: Chamomile essential oil, widely used in the food and medicinal industries, was found to be significantly affected by gallic acid, a biological elicitor. In a study, chamomile plants were sprayed with different dosages of gallic acid. The results showed that the plants treated with 15 mg/L gallic acid produced the highest quantity of flowers and essential oil. The essential oil extracted from untreated plants had the highest concentration of oxygenated sesquiterpenes. This suggests that gallic acid increases the production of essential oil and alters its chemical constituents, thereby affecting its biological activity.
NATURAL PRODUCT RESEARCH
(2023)
Article
Agricultural Engineering
Shalika Rathore, Rakesh Kumar
Summary: The study demonstrated that early sowing and salicylic acid (SA) application are beneficial for improving agronomic traits and yield of German chamomile in the Indian western Himalayan region, while these traits decrease with delayed sowing times. Additionally, sowing time and SA application influence the essential oil yield and chemical constituents of German chamomile.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Biochemistry & Molecular Biology
Nur Zahirah Abd Rani, Kok Wai Lam, Juriyati Jalil, Hazni Falina Mohamad, Mohd Shukri Mat Ali, Khairana Husain
Summary: Phyllanthus amarus and its compound hypophyllanthin have shown potential antiallergic activity by inhibiting the activation of the H1 receptor, as revealed through the study's findings on mast cell degranulation and histamine binding assays.
Article
Biochemistry & Molecular Biology
Mary A. Egbuta, Shane McIntosh, Daniel L. E. Waters, Tony Vancov, Lei Liu
Summary: Natural alpha-bisabolol is widely used in cosmetics and primarily sourced from endangered Candeia trees. The in vitro anti-inflammatory activity of cotton gin trash (CGT) essential oil and beta-bisabolol was studied, showing significant inhibition of inflammatory mediators in a dose-dependent manner. Beta-bisabolol exhibited similar effects to alpha-bisabolol, suggesting its potential for cosmetic and therapeutic applications as an anti-inflammatory agent.
Article
Plant Sciences
Shalika Rathore, Rakesh Kumar
Summary: This study demonstrates that the application of biostimulants and phosphorus fertilizer improves the agro-morphological traits, yield, and essential oil constituents of German chamomile in acidic soils. The highest yield and quality were obtained with phosphorus at 90 kg ha(-1) and humic acid at 10 mL L-1.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Chemistry, Applied
Tingting Zhang, Hualin Wang, Dongxiu Qi, Li Xia, Linlin Li, Xingjiang Li, Shaotong Jiang
Summary: A cellulose acetate membrane incorporated with Perilla frutescens anthocyanins and chamomile essential oil has been developed for food freshness monitoring and shelf-life extending. The membrane exhibits high sensitivity and reversibility towards pH stimuli, as well as good antibacterial and antioxidant activity.
CARBOHYDRATE POLYMERS
(2022)
Review
Food Science & Technology
Tianyu Hou, Siva Sankar Sana, Huizhen Li, Yun Xing, Anima Nanda, Vasudeva Reddy Netala, Zhijun Zhang
Summary: Essential oils are versatile and can be used as substitutes in various sectors. However, there is still a lack of comprehensive understanding about the components and molecular mechanisms of essential oils. Their bioactivity can be compared with synthetic pharmaceutical formulations, and further research is needed to explore their potential applications in nutrition or pharmaceutical companies.
Article
Pharmacology & Pharmacy
Vijayarohini Parasuraman, Akter Mst Sharmin, Mariadoss Arokia Vijaya Anand, Allur Subramaniyan Sivakumar, Duraiarasan Surendhiran, Gopika Sharesh, Seungdo Kim
Summary: In this study, bio-capsules loaded with essential oil were prepared using the ionic gelation method. The effect of different concentrations of crosslinker on the capsules was investigated. The results showed that increasing the amount of essential oil improved the encapsulation efficiency, and the swelling index of the capsules was higher in PBS medium. The linalool-loaded bio-capsules demonstrated significant antibacterial activity against Escherichia coli within 2 hours, making them promising candidates for long-term storage and reduction of environmental bio-contamination.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Plant Sciences
Abbas Ali, Nurhayat Tabanca, Vijayasankar Raman, Cristina Avonto, Xiangbing Yang, Betul Demirci, Ikhlas A. Khan, Amar G. Chittiboyina
Summary: In this study, the essential oils of German chamomile, Roman chamomile, and Chinese chamomile were characterized and tested for their biting deterrence/repellency and toxicity against mosquito and fruit fly species. The results showed that the essential oils of German chamomile and Chinese chamomile had similar repellency effects to DEET against mosquitoes, while the essential oil of Roman chamomile had lower repellency. All essential oils were toxic against fruit flies. Further research will be conducted to explore the potential of these natural products in insect pest management strategies.
RECORDS OF NATURAL PRODUCTS
(2023)
Article
Agriculture, Multidisciplinary
Nawaf Al-Maharik, Nidal Jaradat, Nisreen Al-Hajj, Summayah Jaber
Summary: This study examined the chemical composition and biological properties of Myrtus communis L. leaves from two regions in Palestine, Jericho and Jenin. The results showed that both locations had essential oils with compounds that exhibit antioxidant, antibacterial, and antifungal activities, suggesting their potential for developing natural pharmaceuticals.
CHEMICAL AND BIOLOGICAL TECHNOLOGIES IN AGRICULTURE
(2023)
Article
Biochemistry & Molecular Biology
Ibrahim Seyda Uras, Sherif S. Ebada, Michal Korinek, Amgad Albohy, Basma S. Abdulrazik, Yi-Hsuan Wang, Bing-Hung Chen, Jim-Tong Horng, Wenhan Lin, Tsong-Long Hwang, Belma Konuklugil
Summary: A marine-derived fungus was found to contain two potentially active compounds that could be developed into new remedies for treating COVID-19 and related inflammatory complications.
Article
Chemistry, Applied
Jianmei Yu, Nona Mikiashvili, Rabiatu Bonku, Ivy N. Smith
Summary: The study found that hydrolysis of peanut flour can reduce the immunoreactivity to peanut allergic patients and generate PFH with antioxidant and ACE-inhibitory activities. The fraction smaller than 5 kDa showed higher ACE-inhibitory activity and did not bind IgE of peanut allergic patients.
Article
Chemistry, Medicinal
Avraz F. Anwar, Christopher F. Cain, Michael J. Garza, David Degen, Richard H. Ebright, Juan R. Del Valle
Summary: Pseudouridimycin (PUM) is a promising drug but suffers from rapid decomposition. Researchers have successfully stabilized PUM by modifying its structure, and certain analogues with modifications still retain antibacterial activity.
Article
Biochemistry & Molecular Biology
Wenzhi Song, Ziyue Xu, Peizhong Gao, Xu Liu
Summary: The present study determined the chemical compositions of essential oils from Tadehagi triquetrum and evaluated their antioxidant and anti-cholinesterase activity. A total of 58 organic compounds were identified in the essential oils. The major components were palmitic acid, 1-Octen-3-ol, Caryophyllene, (Z)-18-Octadec-9-enolide, and 3-Hexen-1-ol. The essential oils showed moderate antioxidant and anti-acetylcholinesterase activity.
Article
Multidisciplinary Sciences
Chen Xu, Ning Dong, Kaichao Chen, Xuemei Yang, Ping Zeng, Changshun Hou, Edward Wai Chi Chan, Xi Yao, Sheng Chen
Summary: Vitamin C (VC) has strong bactericidal, anti-biofilm, and virulence-suppressing effects on carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP). It induces reactive oxygen species generation to kill the bacteria and inhibits biofilm formation by suppressing exopolysaccharide (EPS) production. In addition, VC acts as an efflux pump inhibitor to disrupt EPS and capsular polysaccharide transportation, further inhibiting biofilm and capsule formation. Virulence-associated genes in CR-hvKP are downregulated when exposed to sub-MIC of VC. VC could be an effective and safe therapeutic agent for urgent cases when other treatment options fail.
Article
Gastroenterology & Hepatology
Chirag Patel, Keiichiro Sugimoto, Veronique Douard, Ami Shah, Hiroshi Inui, Toshikazu Yamanouchi, Ronaldo P. Ferraris
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
(2015)
Editorial Material
Gastroenterology & Hepatology
Yoshihisa Takahashi, Keiichiro Sugimoto, Hiroshi Inui, Toshio Fukusato
WORLD JOURNAL OF GASTROENTEROLOGY
(2015)
Article
Biotechnology & Applied Microbiology
Yoshihisa Takahashi, Keiichiro Sugimoto, Yurie Soejima, Arisa Kumagai, Tatsuki Koeda, Aiko Shojo, Kazuya Nakagawa, Naoki Harada, Ryoichi Yamaji, Hiroshi Inui, Toshikazu Yamanouchi, Toshio Fukusato
BIOMED RESEARCH INTERNATIONAL
(2015)
Article
Biochemistry & Molecular Biology
Yuko Kobayashi, Harumi Sato, Mika Yorita, Hiroto Nakayama, Hironari Miyazato, Keiichiro Sugimoto, Tomoko Jippo
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
(2016)
Article
Medicine, Research & Experimental
Mai Mitoshi, Isoko Kuriyama, Hiroto Nakayama, Hironari Miyazato, Keiichiro Sugimoto, Yuko Kobayashi, Tomoko Jippo, Kouji Kuramochi, Hiromi Yoshida, Yoshiyuki Mizushina
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
(2014)
Article
Integrative & Complementary Medicine
Keiichiro Sugimoto, Hiroaki Takeuchi, Kazuya Nakagawa, Yasuhiro Matsuoka
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2018)
Article
Endocrinology & Metabolism
Edek A. J. Williams, Veronique Douard, Keiichiro Sugimoto, Hiroshi Inui, Fabienne Devime, Xufei Zhang, Kunihiro Kishida, Ronaldo P. Ferraris, J. Christopher Fritton
CALCIFIED TISSUE INTERNATIONAL
(2020)
Article
Substance Abuse
Yoshihisa Takahashi, Shiori Watabe, Arisa Togashi-Kumagai, Masato Watanabe, Erdenetsogt Dungubat, Hiroyuki Kusano, Yasuyuki Kobayashi, Naoki Harada, Ryoichi Yamaji, Keiichiro Sugimoto, Toshio Fukusato
Article
Biochemistry & Molecular Biology
Keiichiro Sugimoto, Midori Amako, Hiroaki Takeuchi, Kazuya Nakagawa, Morio Yoshimura, Yoshiaki Amakura, Tomoyuki Fujita, Shigeo Takenaka, Hiroshi Inui
Summary: The study found that oenothein B in Eucalyptus leaf extract (ELE) can inhibit fructose absorption without affecting glucose absorption. This discovery has the potential to prevent and improve obesity and other diseases caused by dietary fructose consumption.
Article
Food Science & Technology
Keiichiro Sugimoto, Hiroyuki Fujisawa, Kazuya Nakagawa, Kazuo Yamamoto, Naoko Suzuki, Shin-ichiro Yamashita, Yuta Takahashi, Toshihiro Kakinuma, Asami Baba, Tsuyoshi Takara, Toshikazu Yamanouchi
Summary: This study evaluated the antiobesity effects of Eucalyptus leaf extract (ELE) containing oenothein B. Results showed that subjects in the ELE group had significantly lower levels of abdominal visceral fat area (VFA), waist circumference, muscle mass, body weight, and BMI compared to the placebo group.
FUNCTIONAL FOODS IN HEALTH AND DISEASE
(2022)
Article
Agriculture, Multidisciplinary
Yasuyuki Kobayashi, Natsumi Watanabe, Reina Hiura, Mai Kubota, Kousuke Furuta, Keiichiro Sugimoto, Kaeko Murota, Eri Nakamura, Toshiki Matsuura, Kenji Kai, Takashi Inui, Tomoya Kitakaze, Naoki Harada, Ryoichi Yamaji
Summary: This study provides insights into the transport form and pathway of oleamide, as well as its absorption and metabolism properties. Oleamide is primarily transported via the portal vein as a complex with albumin. It is taken up by CD36 in the small intestine and degraded intracellularly by FAAH.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Yasuyuki Kobayashi, Mai Kubota, Keiichiro Sugimoto, Tomoya Kitakaze, Naoki Harada, Ryoichi Yamaji
Summary: The study found that housing mice in small cages leads to obesity and abdominal fat accumulation, but dietary oleamide can suppress this obesity.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
(2022)
Article
Nutrition & Dietetics
Yasuyuki Kobayashi, Natsumi Watanabe, Tomoya Kitakaze, Keiichiro Sugimoto, Takeshi Izawa, Kenji Kai, Naoki Harada, Ryoichi Yamaji
Summary: The study showed that dietary oleamide can rescue skeletal muscle atrophy in mice, possibly by activating the PI3K/Akt/mTOR signaling pathway and restoring autophagy flux.
BRITISH JOURNAL OF NUTRITION
(2021)
Article
Chemistry, Multidisciplinary
Mia Imanishi, Motohiro Sonoda, Hironari Miyazato, Keiichiro Sugimoto, Mitsugu Akagawa, Shinji Tanimori
Meeting Abstract
Biochemistry & Molecular Biology
C. Patel, K. Sugimoto, A. Shah, S. Parikh, V. Douard, H. Inui, T. Yamanouchi, R. Ferraris
