Article
Plant Sciences
Xiao-Lu Li, Tong Ru, Armando Navarro-Vazquez, Peter Lindemann, Marc Nazare, Xu-Wen Li, Yue-Wei Guo, Han Sun
Summary: This study successfully elucidated the structures of two uncommon marine gorgonian-derived symmetric dimers using various anisotropic and computational NMR methods. Additionally, it revealed the relative configuration of these dimers.
JOURNAL OF NATURAL PRODUCTS
(2022)
Article
Biochemistry & Molecular Biology
Fei-Hua Yao, Xiao Liang, Xia Cheng, Juan Ling, Jun-De Dong, Shu-Hua Qi
Summary: Three new cyclic lipopeptides and four new linear peptides were isolated from a marine fungus, showing significant antifungal activity. The beta-amino fatty acid chain was found to significantly affect the antifungal activity of the cyclic lipopeptides.
Review
Microbiology
Radwa N. Morgan, Amer Al Ali, Mohammad Y. Alshahrani, Khaled M. Aboshanab
Summary: Biofouling, caused by the accumulation of undesired biological materials on submerged surfaces, has negative impacts on the economy and maritime environments. Researchers have been focused on isolating natural antifouling agents from marine actinomycetes as an alternative to synthetic agents. These compounds show promising properties in inhibiting microbial growth and larval settlements, but large-scale production remains a challenge.
Article
Plant Sciences
Zhi-Wen Wu, Zhi-Xuan Wang, Yuan-Qiang Guo, Sheng-An Tang, Dan-Qing Feng
Summary: A new compound (1) and several other compounds (2-10) were isolated from the soft coral Sinularia flexibilis, as well as three diterpenoids (11-13) from the gorgonian Muricella sp. These compounds showed significant antifouling activity against the larval settlement of the bryozoan Bugula neritina. The analysis of structure-activity relationships revealed that the presence of a hydroxy group at C-13 in compound 4 reduced its antifouling activity.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
(2023)
Article
Biotechnology & Applied Microbiology
Christophe Labriere, Gunnar Cervin, Henrik Pavia, Jorn H. Hansen, Johan Svenson
Summary: The study reported the antifouling activity of 29 synthetic analogs inspired by the potent antifouling effect seen for benzo[g]dipodazine, some of which showed inhibitory properties against barnacles at low micromolar concentrations similar to natural barettin. Despite several compounds showing high activity, the remarkable antifouling effect reported for benzo[g]dipodazine was not observed in this study.
MARINE BIOTECHNOLOGY
(2021)
Article
Environmental Sciences
Xi Feng, Ya Gong, Meng-Qi Ye, Zong-Jun Du
Summary: A novel Gram-stain-negative, aerobic coccus with exopolysaccharide (EPS) production ability was isolated from coastal sediment of Xiaoshi Island, Weihai, China under the selective pressure of ofloxacin and norfloxacin. This marine isolate was proposed to be a new species named Pelagicoccus enzymogenes sp. nov. The EPS produced by the strain NFK12(T) may contribute to its tolerance against the inhibitory effects of ofloxacin and norfloxacin.
FRONTIERS IN MARINE SCIENCE
(2021)
Article
Chemistry, Physical
Xiaonan Sun, Linlin Zhang, Rongrong Chen, Jingyuan Liu, Jing Yu, Jiahui Zhu, Peili Liu, Jun Wang, Qi Liu
Summary: A composite system involving a photocatalyst based on 3D network carbon nitride and acrylic fluoroboron polymer was successfully synthesized, showing excellent anti-adhesion performance and antibacterial rates. The self-cleaning function and high efficiency of COD removal were demonstrated due to efficient charge-carrier separation and transfer within the composite system.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Medicinal
Walied M. Alarif, Yasser A. Shaban, Mohammed I. Orif, Mohamed A. Ghandourah, Adnan J. Turki, Hajer S. Alorfi, Hermine R. Z. Tadros
Summary: In this study, a novel eco-friendly approach was used to synthesize titanium dioxide nanoparticles using marine natural extracts. These nanoparticles were incorporated as antifouling agents into newly fabricated marine paint formulations. The results showed that the paints prepared with red algae and marine sponge extracts demonstrated excellent antifouling performance, while heavy fouling was observed on the surface of the commercial paint. The marine extract based titanium dioxide nanoparticles with small crystallite sizes and carbon incorporation are promising candidates for eco-friendly antifouling agents.
Article
Chemistry, Medicinal
Daniela Pereira, Catarina Goncalves, Beatriz T. Martins, Andreia Palmeira, Vitor Vasconcelos, Madalena Pinto, Joana R. Almeida, Marta Correia-da-Silva, Honorina Cidade
Summary: Antifouling coatings with biocidal compounds have been used to prevent biofouling, but eco-friendly alternatives are needed. New synthesized polymethoxylated flavones and chalcones, including those with a triazole moiety, showed antifouling activity. The most potent compound against mussel larvae was a triazolyl glycosylated chalcone, which was non-toxic to Artemia salina, highlighting the importance of developing new synthetic antifouling agents as ecofriendly alternatives for the marine industry.
Article
Chemistry, Medicinal
Mohamed Shaaban, Ghada S. E. Abou-El-Wafa, Christopher Golz, Hartmut Laatsch
Summary: Analysis of the air-dried marine red alga Laurencia papillosa collected near Ras-Bakr at the Suez gulf in Egypt resulted in the discovery of five new halogenated terpene derivatives and their antimicrobial activities were studied.
Article
Chemistry, Applied
Shiming Zhu, Jin Han, Zhichao Yan, Yuze Wu, Wenqing Zhang, Wei Xia, Huafeng Feng
Summary: A novel exopolysaccharide (BD0.4) was purified from Paenibacillus bovis sp. nov BD3526 in wheat bran medium. The structure analysis revealed its composition and branching structure. BD0.4 exhibited enhanced phagocytic ability of macrophages and stimulated the secretion of immune factors from immune cells, possibly through the NF-kappa B signaling pathway.
CARBOHYDRATE POLYMERS
(2022)
Article
Plant Sciences
Abujunaid Khan, Madhukar S. Said, Balasaheb R. Borade, Rajesh Gonnade, Vitthal Barvkar, Ravindar Kontham, Syed G. Dastager
Summary: Three novel compounds and a new acid were identified from the strain Amycolatopsis sp. MCC 0218, and their chemical structures and activities against methicillin-susceptible and -resistant Staphylococcus aureus were determined.
JOURNAL OF NATURAL PRODUCTS
(2022)
Article
Chemistry, Applied
Dhruba Bhattacharya, Tapan Kumar Lai, Amit Saha, Joseph Selvin, Joydeep Mukherjee
Summary: A novel diketopiperazine, (3S, 6S)-3,6-diisobutylpiperazine-2,5-dione, was isolated from a sponge-associated microbe for the first time, characterized through various analytical techniques, and its antibacterial activity against Escherichia coli and Staphylococcus aureus subsp. aureus was reported for the first time. The single crystal X-ray diffraction analysis of this compound was performed, revealing its melting point and providing valuable supplemental data accessible online.
NATURAL PRODUCT RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Jia-Xuan Yan, Qihao Wu, Mitasree Maity, Doug R. Braun, Imraan Alas, Xiao Wang, Xing Yin, Yanlong Zhu, Bailey A. Bell, Scott R. Rajski, Ying Ge, Douglas D. Richardson, Wendy Zhong, Tim S. Bugni
Summary: Cyclic peptides are a promising source of drug leads, but their structural complexity poses challenges for structure elucidation. Isotopic fine structure analysis, NMR, and mass spectrometry techniques were used to determine the sequence and stereochemistry of streptnatamide A, a cyclic peptide from a marine-derived Streptomyces sp. The analysis also tentatively identified and annotated a biosynthetic gene cluster for streptnatamide A based on genomic sequencing data. These analytical tools are valuable for overcoming the challenges of cyclic peptide structure elucidation and accelerating the development of bioactive cyclic peptides.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Biotechnology & Applied Microbiology
Yali Bi, Pengfei Guo, Liangsen Liu, Lei Chen, Weiwen Zhang
Summary: By mining genomic data and using a chemical biology approach, we identified the sterol biosynthesis pathway in Schizochytrium and uncovered the important roles of sterols in growth, carotenoid synthesis, and fatty acid synthesis. We also found possible co-regulation between sterol synthesis and fatty acid synthesis, as well as between sterol synthesis and carotenoid synthesis. These findings lay the foundation for engineering Schizochytrium for sustainable lipid and high-value chemical production.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Food Science & Technology
Wei Jia, Pan Zhuang, Qiao Wang, Xuzhi Wan, Lei Mao, Xinyu Chen, Hong Miao, Dawei Chen, Yiping Ren, Yu Zhang
Summary: Through investigating the urine metabolomes in rats with glycidol or 3-MCPD exposure, new exposure biomarkers were identified, and the impact on metabolic pathways and the surrounding metabolic network were explored.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Agriculture, Multidisciplinary
Dawei Chen, Jingguang Li, Yunfeng Zhao, Yongning Wu
Summary: This article summarizes potential human exposures to Fipronil and results of human biomonitoring studies, emphasizing the importance of such studies for assessing Fipronil exposure and human health risks.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Chemistry, Analytical
Zhibin Liu, Dawei Chen, Bing Lyu, Jingguang Li, Yunfeng Zhao, Yongning Wu
Summary: In human biomonitoring, developing a high-throughput extraction and enrichment method for detecting organic contaminants at the part-per-trillion level is crucial but challenging. This study introduces a cold-induced liquid-liquid extraction (CI-LLE) strategy that integrates the extraction and enrichment in one step, providing a cost-effective and efficient solution for analyzing biological samples.
ANALYTICAL CHEMISTRY
(2022)
Article
Agriculture, Multidisciplinary
Zhibin Liu, Dawei Chen, Bing Lyu, Zeming Wu, Jingguang Li, Yunfeng Zhao, Yongning Wu
Summary: This study investigated the exposure of Chinese infants to phenylpyrazole and diamide insecticides during lactation. The results showed that infants have higher levels of exposure to fipronil than adults, while exposure levels to other types of phenylpyrazoles and diamide insecticides are low.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Biochemical Research Methods
Xueyan Gao, Yuxin Wang, Dawei Chen, Jingguang Li, Yuxin Zhong, Yunfeng Zhao, Yongning Wu
Summary: A rapid and accurate online analysis method was developed for monitoring 46 types of PFAS in human serum. The method showed good linearity, recovery, and precision, and the results indicated high exposure to 6:2 Cl-PFESA in China.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2022)
Article
Chemistry, Applied
Jun Ren, Zhibin Liu, Shaohua Li, Feng Zhu, Lifeng Li, Yunfeng Zhao, Dawei Chen, Yonglin Zhou, Yongning Wu
Summary: The occurrence of fipronil and its three metabolites in tea samples collected from 2011 to 2018 in China was investigated in this study. It was found that the total fipronils in the samples were dominated by fipronil and its major metabolites fipronil desulfinyl and fipronil sulfone. A significant percentage of the tea samples exceeded the maximum residue limits set by the European Union and Japan. However, the chronic exposure risk for Chinese tea consumers was found to be low.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Engineering, Environmental
Jianhui Zhuang, Zhiqiang Jiang, Dawei Chen, Jingguang Li, M. James C. Crabbe, Meiyue Qiu, Yuxin Zheng, Weidong Qu
Summary: Fipronil is a widely used insecticide found in drinking water and food. Its effects on the human thyroid are not well-known.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Chi Zhang, Heli Li, Huijing Shen, Bing Lyu, Shaohua Li, Jingguang Li, Yunfeng Zhao, Dawei Chen, Yongning Wu
Summary: This study is the first nationwide study in China on the chronic health risks of chlorothalonil and its metabolite (4-OH-chlorothalonil) for Chinese adults and breastfed infants. The study found that chlorothalonil and 4-OH-chlorothalonil were detected in dietary samples, with higher levels in Northwest China and Shandong regions. Other exposure routes besides dietary intake were also identified. The study concluded that the chronic health risks from dietary exposure to chlorothalonil and 4-OH-chlorothalonil are low for Chinese adults and breastfed infants.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Environmental Sciences
Dawei Chen, Heli Li, Jiayin Li, Zhibin Liu, Bing Lyu, Jingguang Li, Yunfeng Zhao, Yuxin Zhong, Yongning Wu
Summary: This study assesses the dietary exposure of Chinese adult males and breastfed infants to perchlorate. It finds that Chinese adult males are mainly exposed to perchlorate through vegetable consumption, while the concentrations of perchlorate in breast milk do not significantly differ between urban and rural areas. The exposure of perchlorate in breastfed infants is almost 10-fold greater than that of Chinese adult males.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Qianqian Li, Bei Li, Dawei Chen, Rong Zhang, Shuyan Liu, Shupeng Yang, Yi Li, Jianxun Li
Summary: This study investigated 1720 samples of primary fruits and vegetables collected around China to assess the health risk of eight pyrethroids (PYRs) for adults and children. The results showed that the hazard index (HI) for chronic and acute cumulative dietary exposure ranged from 0.004 to 0.200% and 11.85 to 99.19%, respectively. The nationwide investigation indicated that the cumulative assessments were not hazardous. However, attention should be paid to the acute intake of pear, grape, and lettuce. This study provides compelling evidence for the development of policies and regulations to improve food quality and safety.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Shaohua Li, Lian Wang, Dawei Chen, Hong Li
Summary: This study developed a reliable method to analyze 4-MEI in tea and found that oolong tea had significantly higher levels of 4-MEI compared to other types of tea. The daily intake of 4-MEI among tea consumers was relatively low, but the overall intake of 4-MEI from other foods cannot be ignored.
Article
Food Science & Technology
Yan Li, Shaohua Li, Jun Ren, Jingguang Li, Yunfeng Zhao, Dawei Chen, Yongning Wu
Summary: This study investigated the occurrence and spatial distribution of perchlorate in Chinese tea, finding that it was present in all samples but varied significantly across different regions. The health risk assessment showed that perchlorate exposure through tea consumption was within a safe range, but high tea consumers should be cautious due to potential health risks from other dietary exposure pathways.
CURRENT RESEARCH IN FOOD SCIENCE
(2023)
Article
Food Science & Technology
Rui Wang, Xiuqin Fan, Yuanyuan Lu, Dawei Chen, Yunfeng Zhao, Kemin Qi
Summary: This study found that high-fat diet-induced obesity disrupts bile acids balance, providing evidence for the potential use of acetic acid as a treatment. Acetic acid supplementation promotes the synthesis of specific types of bile acids in the liver and reduces their excretion in feces, thus restoring bile acids balance.
CURRENT RESEARCH IN FOOD SCIENCE
(2022)
Article
Public, Environmental & Occupational Health
Zhibin Liu, Dawei Chen, Bing Lyu, Jingguang Li, Yunfeng Zhao, Yongning Wu
Summary: This report adds that dietary intake of fipronil in China is within acceptable levels with low health risk. Eggs are the main contributor to fipronil intake for Chinese adults, followed by vegetables, meats, and cereals. These findings emphasize the need for strengthened monitoring of fipronil in foods, especially animal-derived products.
Article
Public, Environmental & Occupational Health
Feng Zhu, Yuxin Wang, Hualiang Liu, Bing Lyu, Dawei Chen, Jingguang Li, Wenliang Ji, Yunfeng Zhao, Yongning Wu
Summary: This report adds that in the Sixth China Total Diet Study, acrylamide was detected in 73.3% samples of 12 food categories. The average dietary intake of acrylamide decreased by 45.1% compared to the Fifth China Total Diet Study. Vegetables, cereals, and potatoes were the main contributors to acrylamide exposure at 88.0%.
