Article
Plant Sciences
Enuo Liu, Hiroshi Tsuboi, Shuuji Ikegami, Tomonori Kamiyama, Yukio Asami, Luyi Ye, Munehiro Oda, Zai-Si Ji
Summary: The main components of Nelumbo nucifera leaf extract (NnEx), quercetin-3-O-ss-glucuronide (Q3GA) and quercetin, were found to promote lipid metabolism by inhibiting the cAMP pathway. Ingestion of NnEx may provide a novel treatment for obesity and type II diabetes by modulating fat and sugar absorption.
PLANT FOODS FOR HUMAN NUTRITION
(2021)
Article
Plant Sciences
Jiraporn Laoung-on, Churdsak Jaikang, Kanokporn Saenphet, Paiwan Sudwan
Summary: The study found that the white Nelumbo nucifera petals aqueous extraction (WNAE) can enhance the effects of heavy metals induced by Mancozeb on cattle sperm. By reducing oxidative stress, WNAE can improve sperm quality, including sperm motility, viability, acrosome integrity, and morphology.
Article
Chemistry, Applied
Luyi Ye, Xiaolin Wang, Tomonobu Konno, Xiangyu Gong, Hao Ding, Hua Yan, Zai-Si Ji, Enuo Liu
Summary: The study evaluated the effects of Nelumbo nucifera leaf extract on overweight patients and found that it showed promising results in improving their condition.
NATURAL PRODUCT RESEARCH
(2022)
Article
Nutrition & Dietetics
Zhang Yanan, Ma Lu, Zhang Lu, Huo Jinhai, Wang Weiming
Summary: The study aimed to investigate the effects of lotus leaf ethanol extract (LLEE) on the mechanism of antiobesity and the intestinal microbiota of obese rats. The results showed that LLEE significantly reduced serum cholesterol, triglyceride, and LDL cholesterol levels, decreased fatty deposits in the liver, and reduced inflammatory factors in obese rats. Moreover, LLEE regulated the abundance of intestinal flora, reducing pro-inflammatory bacteria and improving fatty liver and inflammation caused by a high-fat diet.
FRONTIERS IN NUTRITION
(2023)
Article
Plant Sciences
Sung Ho Moon, Euihyun Kim, Hye-In Kim, Soo-Yun Kim, Hyo-Hyun Seo, Jeong Hun Lee, Min-Sup Lee, Seung-Ki Lee, Sang Hyun Moh, Seunghee Bae
Summary: The study found that the extract derived from lotus callus in the Haman region not only has anti-inflammatory, antioxidant, and soothing properties, but also plays an important role in skin whitening. Clinical trials have confirmed the significant whitening effect of cosmetics containing this extract.
Article
Biochemistry & Molecular Biology
Hui-Hsuan Lin, Jen-Ying Hsu, Chiao-Yun Tseng, Xiao-Yin Huang, Hsien-Chun Tseng, Jing-Hsien Chen
Summary: This study investigated the effect of lotus seedpod extract (LSE) on acetaminophen-induced liver toxicity. The results showed that LSE could enhance cell survival, reduce intracellular ROS levels, and decrease apoptosis. The underlying molecular mechanisms involved inhibition of inflammation and restoration of mitochondrial structure. These findings suggest that LSE could be a potential therapeutic option for acetaminophen overdose.
Article
Plant Sciences
Yejin Ahn, Singeun Kim, Chunwoong Park, Jung Eun Kim, Hyung Joo Suh, Kyungae Jo
Summary: This study investigated the sleep-promoting activity of water extract from lotus rhizome (LE). The results showed that LE increased sleep duration by increasing nonrapid eye movement (NREM) sleep, which was associated with the upregulation of GABA(A) receptors and GABA concentration in the brain. This suggests that LE may promote sleep by activating GABA(A) receptors.
PHARMACEUTICAL BIOLOGY
(2022)
Article
Nutrition & Dietetics
Eunji Park, Hojung Choi, Cao-Sang Truong, Hee-Sook Jun
Summary: In this study, it was found that Nelumbo nucifera leaf ethanolic extract has a preventive effect on muscle atrophy induced by dexamethasone. The extract increased the weight, cross-sectional area, and grip strength of muscles in mice. It also decreased the expression of muscle atrophic factors and autophagy factors, and reduced inflammation and cell death-related protein release.
Article
Nutrition & Dietetics
Yao He, Yue Tao, Liang Qiu, Wenfeng Xu, Xiaoli Huang, Hua Wei, Xueying Tao
Summary: In this study, lotus leaves were fermented by two probiotics, and the anti-obesity effects of the fermented lotus leaf supernatant were evaluated. It was found that the fermented lotus leaf supernatant showed potential in inhibiting obesity, making it a possible healthy foodstuff.
Article
Biochemistry & Molecular Biology
Sze-Jack Tan, Chee-Keong Lee, Chee-Yuen Gan, Olusegun Abayomi Olalere
Summary: By optimizing the conditions using Box-Behnken design, it was found that Chinese lotus exhibited higher antioxidant and total flavonoid content compared to Malaysian lotus at the optimum extraction condition.
Review
Food Science & Technology
Zhenyu Wang, Yong Cheng, Maomao Zeng, Zhaojun Wang, Fang Qin, Yongzhi Wang, Jie Chen, Zhiyong He
Summary: Lotus leaves are widely used in food and health products, showing promising health-promoting activities such as anti-diabetes, anti-obesity, and anti-inflammation. However, more research and long-term clinical trials are needed to further understand their therapeutic effectiveness and applications.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Plant Sciences
Jui-Yi Chen, Chia-Lin Tsai, Chiao-Yun Tseng, Pei-Rong Yu, Yu-Hsuan Chang, Yue-Ching Wong, Hui-Hsuan Lin, Jing-Hsien Chen
Summary: This study found that lotus seedpod extract (LSE) can alleviate cisplatin-induced nephrotoxicity by reducing oxidative stress and apoptosis in the kidneys.
Article
Plant Sciences
Cheng-Yong Feng, Shan-Shan Li, Goro Taguchi, Qian Wu, Dan-Dan Yin, Zhao-Yu Gu, Jie Wu, Wen-Zhong Xu, Cheng Liu, Liang-Sheng Wang
Summary: This study identified two C-glycosyltransferase genes in sacred lotus and showed that they play a crucial role in the biosynthesis of flavonoids. The enzymes UGT708N1 and UGT708N2 were found to catalyze the C-glycosylation of 2-hydroxyflavanones and 2-hydroxynaringenin, forming mono-C-glycosides and di-C-glycosides. The research also proposed a new biosynthetic pathway for flavonoid di-C-glycosides and identified a novel uridine diphosphate-glycosyltransferase (UGT708N2) in N. nucifera.
Article
Food Science & Technology
Won-Kyung Cho, Hye Jin Yang, Jin Yeul Ma
Summary: This study demonstrates for the first time that the water extract of lotus leaf has a strong inhibitory effect on influenza A virus infection. Specifically, the extract reduces the expression and activity of viral proteins and inhibits cytopathic effect caused by H1N1 and H3N2 viruses.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Multidisciplinary Sciences
Ivette M. M. Menendez-Perdomo, Peter J. J. Facchini
Summary: Benzylisoquinoline alkaloids (BIAs) are structurally diverse plant specialized metabolites mainly found in the order Ranunculales. The biosynthetic pathways of important BIAs in opium poppy have been elucidated, but little is known about them in sacred lotus. This study identified enzymes responsible for the formation of specific BIAs in sacred lotus and discussed other aspects of the biosynthetic pathways. The findings provide molecular tools for the synthetic biology production of valuable alkaloids.
SCIENTIFIC REPORTS
(2023)