Article
Biochemistry & Molecular Biology
Ramakrishna Ungarala, Manne Munikumar, Sukesh Narayan Sinha, Dileshwar Kumar, R. Shyam Sunder, Suresh Challa
Summary: This study evaluated the therapeutic effects of oxidised Epigallocatechin Gallate (O-EGCG) compared to native EGCG, finding improved antioxidant capacity and anti-inflammatory properties. The O-EGCG showed significant inhibitory action against SARS-CoV-2, suggesting its potential as a treatment for COVID-19. Further in vivo studies and human clinical trials are needed to understand the mechanism of action and confirm its efficacy.
Article
Engineering, Environmental
Soumi Dutta, Ria Sen Gupta, Kunal Manna, Sk Safikul Islam, Suryasarathi Bose
Summary: This study successfully achieved a balance between water permeability and separation abilities in membranes by electrostatically soldering 'green tea' extract EGCG with the membrane's key ingredients. The triple IPN membrane showed excellent antifouling, mechanical and thermal stability, as well as antibacterial and antiviral properties. This research provides guidance for researchers in both academia and industry working on next generation membranes for water remediation.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Plant Sciences
Susmit Mhatre, Tishya Srivastava, Shivraj Naik, Vandana Patravale
Summary: This study reviewed the antiviral activities of tea polyphenols and their interactions with SARS-CoV-2, indicating significant potential in the treatment and prophylaxis of COVID-19. In particular, theaflavin-3,3'-digallate (TF3) showed significant binding with viral receptors, highlighting the efficacy of tea polyphenols against COVID-19.
Review
Biochemistry & Molecular Biology
Victor Valverde-Salazar, Daniel Ruiz-Gabarre, Vega Garcia-Escudero
Summary: Alzheimer's disease (AD) is a common form of dementia characterized by memory decline, cognitive impairment, and several pathological changes in the brain. Oxidative stress and inflammation play important roles in the development of AD. Green tea and its active compound EGCG have shown potential therapeutic effects in modulating AD through their antioxidative and anti-inflammatory properties. EGCG can regulate inflammatory processes, reduce protein aggregation, and promote neuronal survival pathways, making it a suitable candidate for the treatment of neurodegenerative disorders involving oxidative stress and inflammation.
Article
Engineering, Chemical
D. L. Meneses, Y. Ruiz, E. Hernandez, F. L. Moreno
Summary: The study demonstrated that block freeze-concentration is an effective technique for increasing catechin and polyphenol content in green tea, while preserving antioxidant activity and maintaining physicochemical parameters and sensory attributes.
JOURNAL OF FOOD ENGINEERING
(2021)
Review
Food Science & Technology
Xiaoyan Chen, Gene Chi Wai Man, Sze Wan Hung, Tao Zhang, Linda Wen Ying Fung, Chun Wai Cheung, Jacqueline Pui Wah Chung, Tin Chiu Li, Chi Chiu Wang
Summary: Endometriosis, a chronic disorder affecting many women, is currently difficult to treat effectively. However, recent studies have shown that green tea, with its bioactive component EGCG, may have potential therapeutic effects on endometriosis by inhibiting various molecular and cellular mechanisms.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Oncology
Maclaine Parish, Gaelle Massoud, Dana Hazimeh, James Segars, Md Soriful Islam
Summary: This review summarizes the role of green tea in treating gynecological cancers. It examines the chemical and chemopreventive properties of green tea and presents the findings of studies on the effect of green tea on reproductive cancers. The potential benefits of using green tea as a therapeutic strategy for managing female reproductive cancers are discussed.
Article
Nutrition & Dietetics
Weiwei Zeng, Miao Hu, Hon Kit Lee, Elaine Wat, Clara Bik San Lau, Chung Shun Ho, Chun Kwok Wong, Brian Tomlinson
Summary: This study found that repeated administration of green tea extract significantly reduced the systemic exposure of rosuvastatin in healthy volunteers, while soy isoflavones had no significant effect on the pharmacokinetics of the statin. The ABC transporter ABCG2 polymorphism had a significant impact on rosuvastatin exposure but did not affect the interaction with green tea.
FRONTIERS IN NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Su Zhou, Zhelu Bao, Shicheng Ma, Cansong Ou, Hao Hu, Yunyun Yang, Xinyu Feng, Yani Pan, Shuying Gong, Fangyuan Fan, Ping Chen, Qiang Chu
Summary: The study found that Liubao tea extract (LTE) can reconstruct the oral mucosal barrier, promote tissue regeneration, mitigate micro-inflammation, and improve the oral flora composition. Therefore, LTE may be a promising therapeutic strategy for addressing oral health concerns.
Article
Physiology
Kornvipa Settakorn, Sarawut Kongkarnka, Anchan Chompupoung, Saovaros Svasti, Suthat Fucharoen, John B. Porter, Somdet Srichairatanakool, Pimpisid Koonyosying
Summary: This study found that green tea extract rich in epigallocatechin-3-gallate has positive effects in alleviating ineffective erythropoiesis, iron dysregulation, and oxidative stress in beta-thalassemic mice.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Xiaoting Luo, Feifei Lu, Zhiyue Yin, Zhiyun Zhou, Zhongmin Wang, Hongjian Zhang
Summary: This study investigated the effects of flavonoids on the formation of enalaprilat produced by CES1-mediated hydrolysis. Most flavonoids tested showed inhibition on CES1, but unexpected hormetic effects were observed for epigallocatechin and epigallocatechin gallate, with stimulatory effects at low concentrations and enzyme inhibition at high concentrations. Further experiments revealed that oxidative stress reduced CES1 activity in rat liver S9, but EGC or EGCG could rescue the loss of enzyme activity. These findings suggest that the polyphenolic nature of EGC or EGCG might be responsible for rescuing CES1 activity under oxidative stress.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Article
Food Science & Technology
Tran Thi Ngoc Nhung, Nguyen Thi Bao Chau, Ly Thi Minh Hien, Vo Thi Hong Linh, Nguyen Le Ha, Dao Thi Anh Dong
Summary: This study demonstrates that the addition of green tea extract powder can improve the quality and preservation of sponge cakes, as well as provide antioxidant and antimicrobial properties.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2022)
Article
Nutrition & Dietetics
Weiwei Zeng, Miao Hu, Hon Kit Lee, Elaine Wat, Clara Bik San Lau, Chung Shun Ho, Chun Kwok Wong, Brian Tomlinson
Summary: This study investigated the effect of green tea and soy isoflavone extracts on the pharmacokinetics of simvastatin in healthy subjects. It found that the intake of soy isoflavones reduced the systemic exposure to simvastatin acid, and this effect was dependent on the SLCO1B1 genotype. The study also showed no overall effect of green tea extract on simvastatin pharmacokinetics.
FRONTIERS IN NUTRITION
(2022)
Article
Multidisciplinary Sciences
Annalisa Romani, Gabriele Simone, Margherita Campo, Lorenzo Moncini, Roberta Bernini
Summary: The antifungal activities of tannins-rich commercial sweet chestnut wood and green tea leaf extracts were evaluated against various filamentous fungi, showing higher inhibitory effects with increasing concentrations.
Article
Biochemistry & Molecular Biology
Rong-zu Nie, Mei-zhu Dang, Zhen-zhen Ge, Yin-qiang Huo, Bo Yu, Shang-wen Tang
Summary: This study investigated the significance of gallate moiety on the antibacterial activities of polyphenols using EGCG and EGC. The findings revealed that the gallate moiety played a crucial role in enhancing the affinity and structure-perturbing potency of EGCG towards the POPG lipid bilayer.
BIOPHYSICAL CHEMISTRY
(2021)
