Article
Biotechnology & Applied Microbiology
Reham Alaa Eldin Shaker, Yosra Ibrahim Nagy, Mina E. Adly, Rania Abdelmonem Khattab, Yasser M. Ragab
Summary: In this study, bacterial consortia capable of degrading CIP and LEV were obtained from industrial wastewater. The impacts of critical operating parameters on the degradation of CIP and LEV were investigated, and the possible degradation pathways were suggested by analyzing the intermediate degradation products. This study discovers the ability of previously unreported bacterial strains to degrade both CIP and LEV.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2022)
Article
Veterinary Sciences
Katarzyna Pietruszka, Lukasz Panasiuk, Piotr Jedziniak
Summary: This study investigated the occurrence of ENNs and BEA in milk in Poland. The results showed that there was constant but low contamination of ENN B and BEA in milk. This suggests that there is no immediate risk to milk consumers, but the potential long-term effects of exposure to low levels of toxins are still unknown.
JOURNAL OF VETERINARY RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Chunshuang Liu, Mingyue Han, Honglei Wang, Xiaojie Chen, Yaoxin Tang, Daokang Zhang, Xiubo Li, Yiming Liu
Summary: This study aimed to optimize UPLC-MS/MS conditions to obtain residual parameters in milk and determine the conclusive drug withdrawal period for food safety. A UPLC-MS/MS method was developed to study cefquinome sulfate's residue elimination in milk and calculate its withdrawal period.
Article
Food Science & Technology
Fulya Tasci, Hale Secilmis Canbay, Mahmut Doganturk
Summary: The study found antibiotic residues in non-compliant milk samples, suggesting that not all milk producers adhere to good veterinary practices.
Article
Biochemistry & Molecular Biology
Marta Pietruk, Piotr Jedziniak, Malgorzata Olejnik
Summary: A novel LC-MS/MS method for NSAIDs determination in meat and milk was developed and validated. Modifications were made to the sample preparation and clean-up procedures, and the method was found suitable for confirmatory purposes in milk and muscle. Two out of 452 samples tested in 2019 and 2020 were identified as non-compliant.
Article
Environmental Sciences
Hanna Mojska, Iwona Gielecinska, Joanna Winiarek, Wlodzimierz Sawicki
Summary: The study found that the level of acrylamide in colostrum was significantly lower than in mature milk, and that breastfeeding women had significantly lower acrylamide intake from hospital diets compared to home diets. There was a positive correlation between dietary acrylamide intake by breastfeeding women and its content in breast milk.
Article
Chemistry, Analytical
Nafiseh Bagheri, Haider A. J. Al Lawati, Nada A. Al Sharji, Javad Hassanzadeh
Summary: The 2D metal-organic framework (MOF) proved to be an efficient adsorbent for simultaneous extraction of fluoroquinolones (FQs). The use of acetic acid solution for elution showed high recovery without the need for toxic organic solvents. The method demonstrated great selectivity and sensitivity in detecting OF, NOR, and CIP in milk samples.
Article
Food Science & Technology
Veronika Walser, Markus Kranzler, Corinna Dawid, Monika Ehling-Schulz, Timo D. Stark, Thomas F. Hofmann
Summary: Study shows that cereulide tends to accumulate in the lipid phase of milk samples, highlighting the importance of intensified analysis of lipid-enriched dairy products to prevent food contamination.
Review
Nutrition & Dietetics
Laurien Ulfman, Angela Tsuang, Aline B. Sprikkelman, Anne Goh, R. J. Joost van Neerven
Summary: The incidence of food allergies has increased worldwide in the past 20 years. Early introduction of allergenic foods has been shown to reduce the risk of allergies, but less is known about the introduction of cow's milk. Recent studies suggest that early introduction of cow's-milk-based formulas with intact milk proteins can reduce the risk of cow's milk allergy, while very early introduction followed by discontinuation may increase the risk.
Article
Chemistry, Applied
Joost L. D. Nelis, Amanda L. Dawson, Utpal Bose, Alisha Anderson, Michelle L. Colgrave, James A. Broadbent
Summary: Accidental milk cross-contamination is a common cause for food recalls, but current methods for quantifying trace-level allergens are not suitable for routine analysis. Here, a rapid LC-MS method was developed to quantify milk allergens, using specific peptides and allergen epitopes. The method showed good sensitivity, recovery rates, and a wide linear range, making it useful for routine determination of trace-contamination and adulteration of dairy products.
Article
Chemistry, Applied
Dermot Faulkner, Margaret L. Cantley, David G. Kennedy, Christopher T. Elliott, Steven R. H. Crooks
Summary: This article reports a method for determining the total content of florfenicol in milk that meets the definition of marker residue for the first time. The method uses an improved UHPLC-MS/MS multiple reaction monitoring-cubed method, which enables more selective detection and quantitation of low levels of florfenicol amine in milk. Validation data and a withdrawal profile in bovine milk are presented.
Article
Food Science & Technology
Wenjuan Chen, Xiaohui Chen, Yun Qian, Xingyun Wang, Yahui Zhou, Xiangyun Yan, Boshi Yu, Shuwen Yao, Zhangbin Yu, Jingai Zhu, Shuping Han
Summary: The study reveals the complexity of lipid expression profiles in exosomes derived from preterm and term human milk. The top 50 lipids identified in the exosomes regulate intestinal epithelial cell function via the ERK/MAPK pathway, providing novel mechanistic insight on how human milk prevents the development of necrotizing enterocolitis (NEC).
MOLECULAR NUTRITION & FOOD RESEARCH
(2021)
Article
Chemistry, Applied
Feifei Sun, Peixu Wu, Mohamed F. Abdallah, Haiguang Tan, Yi Li, Shupeng Yang
Summary: This study proposed and validated a novel strategy of one sample multi-point calibration curve (OSCC) using multiple isotopologue reaction monitoring (MIRM) for quantitative LC-MS bioanalysis. The developed OSCC methodology exhibited good performance in selectivity, sensitivity, accuracy, and precision, and could realize sample dilution by monitoring the MIRM channel. The advantages of excluding the preparation of multi-sample external calibration curve (MSCC) and sample dilution in OSCC make this strategy widely applicable in various fields.
Article
Agriculture, Multidisciplinary
Myriam Bustamante-Rangel, Maria Milagros Delgado-Zamarreno, Encarnacion Rodriguez-Gonzalo
Summary: A simple and sensitive method has been developed for the analysis of anthelmintic drugs in milk, involving extraction using QuEChERS method and separation and determination by LC-MS/MS. This method provides high sensitivity for the determination of anthelmintics in milk samples and can be successfully used for routine analysis.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Food Science & Technology
Natalia Zofia Maryniak, Ana Isabel Sancho, Egon Bech Hansen, Katrine Lindholm Bggh
Summary: Cow's milk allergy is the most prevalent type of food allergy among infants. There is a growing demand for more options for infant feeding, especially for the prevention and management of cow's milk allergy. Milk from other mammalian sources and proteins from plant sources have gained increased interest due to their potentially lower allergenicity.
Article
Biochemical Research Methods
Chang-Shun Liu, Xiao Liang, Xiao-Han Wei, Fei-Long Chen, Qing-Fa Tang, Xiao-Mei Tan
BIOMEDICAL CHROMATOGRAPHY
(2019)
Article
Biochemical Research Methods
Chang-Shun Liu, Xiao Liang, Xiao-Han Wei, Fei-Long Chen, Qing-Fa Tang, Xiao-Mei Tan
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2019)
Article
Microbiology
Chang-Shun Liu, Xiao Liang, Xiao-Han Wei, Zhen Jin, Fei-Long Chen, Qing-Fa Tang, Xiao-Mei Tan
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Integrative & Complementary Medicine
Xiao Liang, Chang-Shun Liu, Ting Xia, Qing-Fa Tang, Xiao-Mei Tan
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2020)
Article
Nanoscience & Nanotechnology
Chang-Shun Liu, Li Chen, Yan-Nan Hu, Jin-Lian Dai, Biao Ma, Qing-Fa Tang, Xiao-Mei Tan
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2020)
Article
Immunology
Xiao Liang, Chang-Shun Liu, Xiao-Han Wei, Ting Xia, Fei-Long Chen, Qing-Fa Tang, Meng-Yue Ren, Xiao-Mei Tan
JOURNAL OF IMMUNOLOGY RESEARCH
(2020)
Article
Plant Sciences
Chang-Shun Liu, Ting Xia, Zhen-Ye Luo, Yuan-Yuan Wu, Yan-Nan Hu, Fei-Long Chen, Qing-Fa Tang, Xiao-Mei Tan
Summary: This study evaluated the pharmacological mechanism of Xianglian pill (XLP) in treating ulcerative colitis (UC) through a combination of network pharmacology and pharmacokinetics analysis. The results showed that XLP mainly alleviates UC inflammation by regulating key pathways of the immune system and inhibiting Th17 cell differentiation. Pharmaceutical studies also confirmed the exposure of XLP ingredients in plasma and colon tissue, demonstrating its therapeutic effect on UC.
Article
Biochemical Research Methods
Xinyu Wang, Xiaohan Wei, Qingfa Tang, Wei Zhong Huang, Yunxia Teng, Zhizhong Liao, XiaoMei Tan, Xin Mao
Summary: This study utilized HPLC technology to research Ficus Microcarpae Folium from different geographical regions, revealing that the main compositions were similar but the content varied. Peaks 8, 15, 12, 11, 16, 3, and 21 were the main components contributing to the differences. Isovitexin, vitexin, and isoorientin were key components reflecting the quality of Ficus Microcarpae Folium.
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
(2021)
Article
Biochemical Research Methods
Chang-Shun Liu, Yan-Nan Hu, Zhen-Ye Luo, Ting Xia, Fei-Long Chen, Qing-Fa Tang, Xiao-Mei Tan
Summary: The combination of Phellodendri Chinensis Cortex (PCC) and Atractylodis Rhizoma (AR) improves the intestinal absorption of alkaloids and reduces their urinary excretion, leading to increased systemic exposure. This study may explain the synergistic effects of PCC and AR in clinical applications.
BIOMEDICAL CHROMATOGRAPHY
(2022)
Article
Plant Sciences
Shuyu Li, Qixin Yang, Feilong Chen, Linhua Tian, Jinhai Huo, Yanli Meng, Qingfa Tang, Weiming Wang
Summary: This study investigates the antipulmonary fibrosis mechanism of Pheretima protein and its possible cell signaling pathways. The results demonstrate that Pheretima protein can inhibit epithelial-mesenchymal transition, reduce inflammation, and alleviate BLM-induced pulmonary fibrosis in a mouse model. The preliminary mechanistic studies suggest that Pheretima protein exerts its biological activity by downregulating the TGF-β1/Smad2/3 pathway.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Plant Sciences
Yuan-Yuan Wu, Shu-Yu Li, Hui-Qing Zhu, Zi-Ming Zhuang, Meng Shao, Fei-Long Chen, Chang-Shun Liu, Qing-Fa Tang
Summary: The study revealed that Hehuan Yin decoction (HHY) may treat polycystic ovary syndrome with insulin resistance (PCOS-IR) through multiple pharmacological pathways, making it a potential alternative therapy for PCOS-IR.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Plant Sciences
Qingfa Tang, Haihong Cao, Ni Tong, Yuanliang Liu, Wanyu Wang, Yuheng Zou, Lanyang Xu, Zhiyun Zeng, Wei Xu, Zhixin Yin, Wenjuan Ma, Qirui Wang
Summary: This study demonstrates that traditional Chinese medicine tubeimoside-I (TBMS1) has a synergistic therapeutic effect against TMZ-resistant glioblastoma multiforme by promoting apoptosis and inhibiting cell proliferation.
Article
Chemistry, Medicinal
Bishan Huang, Hanhe Liu, Yingyao Wu, Chan Li, Qingfa Tang, Yuan-Wei Zhang
Summary: Albizia julibrissin Durazz. is a common herb used for depression and anxiety treatment, but its mechanism of action is not yet fully understood. This study identified two lignan glycosides in Albizia julibrissin Durazz. that inhibit serotonin transporter (SERT) by inducing a conformational shift in SERT, resulting in decreased serotonin reuptake and potential antidepressant and anxiolytic effects.
Article
Biophysics
Qingfa Tang, Yankui Yi, Yao Chen, Ziming Zhuang, Feng Wang, Lu Zhang, Shenkun Wei, Yusheng Zhang, Yueqiusha Wang, Li Liu, Qiang Liu, Cuiping Jiang
Summary: This study introduces a green and efficient method for the delivery of key components from Salvia miltiorrhiza and Carthamus tinctorius, showing significant anti-atherosclerotic effects.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Plant Sciences
Chunyang Tian, Hefei Huang, Yuanru Zheng, Xuemei He, Lijun Yan, Lingzhu Shi, Tangjia Yang, Xi Chen, Jiabin Yang, Zibin Lu, Huihui Cao, Wei Zhao, Zhiran Qin, Jianhai Yu, Qingfa Tang, Xiankun Tong, Junshan Liu, Linzhong Yu
Summary: This study found that Ampelopsis Radix, a traditional Chinese medicine, has anti-dengue virus activity. It inhibits virus replication by blocking virus-cell binding and significantly alleviates disease symptoms and pathological damage in infected mice.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)