Article
Clinical Neurology
Lingxiao Cao, Hailong Li, Xinyu Hu, Jing Liu, Yingxue Gao, Kaili Liang, Lianqing Zhang, Xinyue Hu, Xuan Bu, Lu Lu, Yanlin Wang, Shi Tang, Qiyong Gong, Xiaoqi Huang
Summary: This study aimed to identify pathophysiological specifics in OCD with different onset times by assessing amygdala subregional functional connectivity alterations. The findings emphasized different patterns of amygdala subregional connectivity alterations associated with EO-OCD and LO-OCD patients, providing unique insights into constructing distinct OCD subtypes based on brain intrinsic connectivity. Specific management for EO-OCD and LO-OCD patients may be needed based on these results.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychology, Clinical
Katherine Parkin, Shanquan Chen, Marjan Biria, James Plaistow, Helen Beckwith, Isaac Jarratt-Barnham, Nuria Segarra, Yulia Worbe, Naomi A. Fineberg, Rudolf N. Cardinal, Trevor W. Robbins, Emilio Fernandez-Egea
Summary: Obsessive-compulsive symptoms (OCS) commonly occur in patients treated with clozapine and can significantly affect subjective wellbeing. This study found that OCS severity had a negative impact on wellbeing scores, independent of depressive and psychotic symptoms. However, OCS did not impair general functioning. Obsessional thinking and hoarding behavior, rather than compulsions, were specifically associated with decreased wellbeing, possibly due to the nature of the compulsions.
PSYCHOLOGICAL MEDICINE
(2023)
Review
Clinical Neurology
Hollie A. L. Burton, Luise Pickenhan, Claire Carson, Paul Salkovskis, Fiona Alderdice
Summary: This review synthesized evidence on the experiences of maternity care and mental health care for women with Obsessive Compulsive Disorder (OCD) during pregnancy and postpartum. The findings revealed three descriptive themes: experiences of barriers to treatment and care, experiences of treatment/care decision making, and experiences of treatment and care. Three analytic themes were also identified, which demonstrated tensions in balancing the health and safety of the baby and the mother, as well as the perception of a normal perinatal experience. The review highlighted significant gaps in the literature, particularly regarding maternity and pharmacological care experiences. Balancing these tensions is crucial to ensure that women with OCD receive the necessary care.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychology, Multidisciplinary
Liliana Dell'Osso, Benedetta Nardi, Chiara Bonelli, Davide Gravina, Francesca Benedetti, Luca Del Prete, Gabriele Massimetti, Giulia Amatori, Barbara Carpita, Ivan Mirko Cremone
Summary: Recent research emphasizes the importance of a dimensional perspective on mental disorders, particularly the conceptualization of an obsessive-compulsive spectrum. The current study aims to evaluate the psychometric characteristics of the Obsessive-Compulsive Spectrum-Short Version (OBS-SV) questionnaire. The results demonstrate strong reliability and validity of the OBS-SV, showing significant correlations with other measures of obsessive-compulsive symptoms.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Psychiatry
Tamar C. Katz, Thanh Hoa Bui, Jennifer Worhach, Gabrielle Bogut, Kinga K. Tomczak
Summary: Tourettic OCD (TOCD) is a unique condition with overlapping symptoms of OCD and CTD. It is characterized by complex tic-like behaviors with compulsive and anxious features. TOCD is an intermediate neuropsychiatric disorder distinct from TS or OCD alone. The treatment of TOCD is complex and often resistant to treatment, requiring a combination of pharmacology and behavioral therapy.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychiatry
Mariela Rance, Zhiying Zhao, Brian Zaboski, Stephen A. Kichuk, Emma Romaker, William N. Koller, Christopher Walsh, Cheyenne Harris-Starling, Suzanne Wasylink, Thomas Adams Jr, Patricia Gruner, Christopher Pittenger, Michelle Hampson
Summary: This study aimed to use fMRI neurofeedback as a treatment for OCD. The results showed that neurofeedback targeting the aPFC can reduce symptoms in OCD, but did not significantly affect control over the aPFC. Future studies should optimize the training protocol and clarify the mechanism of action.
PSYCHIATRY RESEARCH
(2023)
Article
Psychology, Clinical
Inkyung Park, Minji Ha, Taekwan Kim, Silvia Kyungjin Lho, Sun-Young Moon, Minah Kim, Jun Soo Kwon
Summary: This study found that patients with early-onset OCD exhibited greater cortical gyrification compared to those with late-onset OCD and healthy controls. Moreover, impaired neurocognitive functions in early-onset OCD patients were correlated with increased gyrification.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Vera Nezgovorova, Casara Jean Ferretti, Stefano Pallanti, Eric Hollander
Summary: Exacerbation or new onset of OCD symptoms during COVID-19 is an understudied area. Increased proinflammatory immune response in COVID-19 patients may be associated with the onset of obsessive-compulsive symptoms, and targeted anti-cytokine treatments can help mitigate these symptoms.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Psychology, Multidisciplinary
Johanna Otte, Nathalie Schicktanz, Dorothee Bentz
Summary: The aim of this study was to investigate the change in obsessive-compulsive symptoms (OCSs) from before to during the COVID-19 pandemic within the Swiss general population, and to examine the possible relationship of OCSs to stress and anxiety. The results showed that OCSs significantly increased during the pandemic, particularly in the washing dimension. Self-reported stress and anxiety were weakly associated with the severity of OCSs. The study suggests that all individuals with OCSs should be considered as risk groups for symptom deterioration during a pandemic and when assessing its possible long-term effects.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Psychology, Multidisciplinary
Katalin Csigo
Summary: Obsessive-compulsive disorder (OCD) is a difficult-to-treat disorder with diverse symptoms. This study focuses on object relations theory to understand OCD symptoms, particularly the concept of the obsessive position. The study distinguishes between the obsessive ego-state and the realistic ego-state, proposing OCD as a disorder of personality and ego organization. The application of a modified psychoanalytic methodology is advocated, with a glimpse into a psychoanalytic therapy session with an OCD patient.
CURRENT PSYCHOLOGY
(2023)
Article
Clinical Neurology
Yimeng Pan, Chuanyong Xu, Tingxin He, Zhen Wei, Carol A. Seger, Qi Chen, Ziwen Peng
Summary: Background:The relationship between cognitive function and psychopathological symptoms has been an important research field. Methods:This study used network analysis to construct networks of cognitive variables and OCD-related symptoms in patients with OCD and healthy controls. Results:The study highlighted the important role of variables such as obsession and IQ from a network perspective. Conclusions: These results deepen our understanding of the multivariate relationship between cognitive dysfunction and OCD symptoms and may promote the prediction and diagnosis of OCD.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Editorial Material
Clinical Neurology
Trevor. W. Robbins
Summary: This scientific commentary discusses the research conducted by Kim et al. on the unbalanced fronto-pallidal neurocircuit underlying set shifting in patients with obsessive-compulsive disorder, published in the journal Brain.
Article
Psychiatry
Ana Beatriz Ravagnani Salto, Marcos L. Santoro, Marcelo Q. Hoexter, Andrea Parolin Jackowski, Pedro M. Pan, Maria Conceicao Rosario, Sintia Belangero, Pedro Gomes Alvarenga, Victoria Fogaca Doretto, Afonso Mazine Tiago Fumo, Marcelo C. Batistuzzo, Pedro Macul Ferreira de Barros, Kiara R. Timpano, Vanessa K. Ota, Luis Augusto Rohde, Euripedes Constantino Miguel, James F. Leckman, Andre Zugman
Summary: The study found a significant relationship between OCS and the symmetrized percent change (SPC) of the right thalamus volume in children, but there was no significant relationship between changes in thalamic volume SPC and OCD-PRS. These findings suggest the need for further research to confirm the results and further characterize the specific nature of OCS symptoms associated with thalamic volumes.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
Amanda R. Mahnke, Omer Linkovski, Kiara Timpano, Peter van Roessel, Catherine Sanchez, Andrea D. Varias, Pavithra Mukunda, Maria Filippou-Frye, Anthony Lombardi, Hannah Raila, Kelley Anderson, Thasveen Sandhu, Brianna Wright, Elizabeth A. McCarthy, Geronimo E. Garcia, Sepehr Asgari, Tori Qiu, Rebecca Bernert, Carolyn Rodriguez
Summary: Hoarding disorder (HD) is a mental disorder characterized by difficulty parting with possessions and impairing life functioning. Research shows that individuals with HD have poor sleep quality, higher levels of insomnia symptoms, and comorbid sleep disorders. Sleep may be a new target for treatment in improving outcomes for individuals with HD.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Clinical Neurology
Anette-Eleonore Schrag, Davide Martino, Hanyuying Wang, Gareth Ambler, Noa Benaroya-Milstein, Maura Buttiglione, Francesco Cardona, Roberta Creti, Androulla Efstratiou, Tammy Hedderly, Isobel Heyman, Chaim Huyser, Pablo Mir, Astrid Morer, Natalie Moll, Norbert E. Muller, Kirsten R. Muller-Vahl, Kerstin J. Plessen, Cesare Porcelli, Renata Rizzo, Veit Roessner, Markus Schwarz, Zsanett Tarnok, Susanne Walitza, Andrea Dietrich, Pieter J. Hoekstra
Summary: This study aimed to investigate the association between group A streptococcal (GAS) infections and tic incidence among unaffected children with a family history of chronic tic disorders (CTDs). Findings showed a strong association between sex and tic onset, with girls having a lower risk of developing tics compared to boys. However, there was no statistical evidence to suggest an association between GAS exposure and tic onset.
Review
Neurosciences
Odile A. van den Heuvel, Premika S. W. Boedhoe, Sara Bertolin, Willem B. Bruin, Clyde Francks, Iliyan Ivanov, Neda Jahanshad, Xiang-Zhen Kong, Jun S. Kwon, Joseph O'Neill, Tomas Paus, Yash Patel, Fabrizio Piras, Lianne Schmaal, Carles Soriano-Mas, Gianfranco Spalletta, Guido A. van Wingen, Je-Yeon Yun, Chris Vriend, H. Blair Simpson, Daan van Rooij, Marcelo Q. Hoexter, Martine Hoogman, Jan K. Buitelaar, Paul Arnold, Jan C. Beucke, Francesco Benedetti, Irene Bollettini, Anushree Bose, Brian P. Brennan, Alessander S. De Nadai, Kate Fitzgerald, Patricia Gruner, Edna Gruenblatt, Yoshiyuki Hirano, Chaim Huyser, Anthony James, Kathrin Koch, Gerd Kvale, Luisa Lazaro, Christine Lochner, Rachel Marsh, David Mataix-Cols, Pedro Morgado, Takashi Nakamae, Tomohiro Nakao, Janardhanan C. Narayanaswamy, Erika Nurmi, Christopher Pittenger, Y. C. Janardhan Reddy, Joao R. Sato, Noam Soreni, S. Evelyn Stewart, Stephan F. Taylor, David Tolin, Sophia I. Thomopoulos, Dick J. Veltman, Ganesan Venkatasubramanian, Susanne Walitza, Zhen Wang, Paul M. Thompson, Dan J. Stein
Summary: Neuroimaging has significantly advanced our understanding of OCD's neurobiology, with ENIGMA consortium's collaborative efforts enhancing statistical power. Their work involves samples from multiple countries and regions, utilizing machine learning techniques for research, contributing to the development of neurobiological models of OCD and global scientific collaboration.
HUMAN BRAIN MAPPING
(2022)
Article
Clinical Neurology
Hai-Di Shan, Yong-Ming Wang, Hui-Xin Hu, Shu-Yao Jiang, Min-Yi Chu, Yi Wang, Simon S. Y. Lui, Eric F. C. Cheung, Zhen Wang, Raymond C. K. Chan
Summary: Our study revealed that individuals with schizo-obsessive traits exhibited increased resting-state functional connectivity within the executive control network, while schizotypal individuals and individuals with obsessive-compulsive symptoms showed the opposite pattern.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2022)
Article
Psychology, Clinical
Minyi Chu, Tingting Xu, Yi Wang, Pei Wang, Qiumeng Gu, Qiang Liu, Eric F. C. Cheung, Raymond C. K. Chan, Zhen Wang
Summary: The study revealed that OCD patients with different levels of childhood trauma exhibit different pathological alterations in thalamic functional connectivity, indicating that childhood trauma may be a predisposing factor for some OCD patients.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Psychiatry
Hai-di Shan, Ya-fei Liu, Qing Zhao, Yi Wang, Yong-ming Wang, Eric F. Cheung, Raymond C. Chan, Zhen Wang
Summary: The study revealed distinct neural correlates in different subgroups of OCD patients based on obsessive beliefs and impulsivity, suggesting potential implications for future research and clinical treatment.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2022)
Article
Psychiatry
Fabrizio Piras, Federica Piras, Yoshinari Abe, Sri Mahavir Agarwal, Alan Anticevic, Stephanie Ameis, Paul Arnold, Nerisa Banaj, Nuria Bargallo, Marcelo C. Batistuzzo, Francesco Benedetti, Jan-Carl Beucke, Premika S. W. Boedhoe, Irene Bollettini, Silvia Brem, Anna Calvo, Kang Ik Kevin Cho, Valentina Ciullo, Sara Dallaspezia, Erin Dickie, Benjamin Adam Ely, Siyan Fan, Jean-Paul Fouche, Patricia Gruner, Deniz A. Guersel, Tobias Hauser, Yoshiyuki Hirano, Marcelo Q. Hoexter, Mariangela Iorio, Anthony James, Y. C. Janardhan Reddy, Christian Kaufmann, Kathrin Koch, Peter Kochunov, Jun Soo Kwon, Luisa Lazaro, Christine Lochner, Rachel Marsh, Akiko Nakagawa, Takashi Nakamae, Janardhanan C. Narayanaswamy, Yuki Sakai, Eiji Shimizu, Daniela Simon, Helen Blair Simpson, Noam Soreni, Philipp Staempfli, Emily R. Stern, Philip Szeszko, Jumpei Takahashi, Ganesan Venkatasubramanian, Zhen Wang, Je-Yeon Yun, Dan J. Stein, Neda Jahanshad, Paul M. Thompson, Odile A. van den Heuvel, Gianfranco Spalletta, Francesca Assogna, Rosa Calvo, Stella J. de Wit, Morgan Hough, Masaru Kuno, Euripedes C. Miguel, Astrid Morer, Christopher Pittenger, Sara Poletti, Enrico Smeraldi, Joao R. Sato, Aki Tsuchiyagaito, Susanne Walitza, Ysbrand D. van der Werf, Daniela Vecchio, Mojtaba Zarei
Summary: The study investigated microstructural alterations in cortico-subcortical connections in OCD patients, finding significant FA reduction in certain brain regions in adults but not in children. Lower FA was associated with younger age of onset, longer duration of illness, and higher percentage of medicated patients.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Clinical Neurology
Jiayue Cheng, Yanyan Ren, Qiumeng Gu, Yongguang He, Zhen Wang
Summary: This study found through QEEG analysis that in the beta band, the assortativity of the right temporal, right parietal, and right occipital cortex in the response group was significantly higher than that in the non-response group; in the theta band, the assortativity of the left frontal, parietal, right occipital cortex, and central area was higher in the response group compared to the non-response group.
CLINICAL EEG AND NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Dong-Dong Shi, Ying-Dan Zhang, Yan-Yan Ren, Shi-Yu Peng, Ti-Fei Yuan, Zhen Wang
Summary: This study suggests that early-life stress can have differing effects on stress resilience depending on whether the stress is predictable or unpredictable. The researchers found that unpredictable maternal separation in rats led to impairments in glutamatergic synapses in the mPFC, while predictable maternal separation promoted stress resilience. Oxytocin signaling in the mPFC was identified as a key factor in determining the effects of early-life stress on stress susceptibility in rats.
MOLECULAR PSYCHIATRY
(2021)
Article
Biochemistry & Molecular Biology
Xiaoyu Chen, Zhen Wang, Qian Lv, Qiming Lv, Guido van Wingen, Egill Axfjord Fridgeirsson, Damiaan Denys, Valerie Voon, Zheng Wang
Summary: The study identified shared downregulated cortico-subcortical and upregulated cortico-cortical network communication induced by both DBS and capsulotomy. Furthermore, increased cortico-cortical communication at ventrolateral and centrolateral prefrontal cortices induced by DBS and capsulotomy contributed to improvement of mood and anxiety symptoms, respectively. Importantly, pretreatment communication of ventrolateral and centrolateral prefrontal cortices were differentially predictive of mood and anxiety improvements by DBS and capsulotomy.
MOLECULAR PSYCHIATRY
(2022)
Article
Psychiatry
Shuangyi Zhou, Shanshan Su, Ang Hong, Chen Yang, Qiang Liu, Wei Feng, Zhen Wang
Summary: The study investigated abnormal brain regions in patients with panic disorder (PD) and found increased thalamic resting-state functional connectivity (rsFC) with the insula, which was significantly correlated with HAMA-somatic score. The advanced fear network model (FNM) may provide a more comprehensive explanation for PD.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
(2022)
Review
Neurosciences
Hanyang Ruan, Yang Wang, Zheqin Li, Geya Tong, Zhen Wang
Summary: This systematic review examined recent studies on outcome prediction of obsessive-compulsive disorder (OCD) patients treated with deep brain stimulation (DBS). The review found that a specific tract confirmed by magnetic resonance imaging (MRI) could predict DBS outcomes for OCD patients, regardless of implant targets, although inconsistencies still exist. Various successful treatment prediction methods were identified in current studies. However, due to heterogeneous results, future research should utilize larger sample sizes and more precise measures, and establish more personalized surgical approaches for DBS.
Article
Health Care Sciences & Services
Yiwen Wu, Xin Li, Yuxin Zhou, Rui Gao, Kaifeng Wang, Huiling Ye, Na Lyu, Chun Wang, Ning Zhang, Zhen Wang, Qing Fan
Summary: This study compares the efficacy and cost-effectiveness of internet-based cognitive behavioral therapy (ICBT) combined with medication, face-to-face cognitive behavioral group therapy (CBGT) combined with medication, and conventional medical treatment for adults with obsessive-compulsive disorder (OCD). The results show that ICBT combined with medication is as effective as CBGT combined with medication for treating OCD and is more cost-effective.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Review
Psychiatry
Zheqin Li, Geya Tong, Yang Wang, Hanyang Ruan, Zifeng Zheng, Jiayue Cheng, Zhen Wang
Summary: This study found that patients with OCD and EDs exhibit impaired inhibitory control, but there are differences in neural activation patterns.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
(2023)
Review
Psychiatry
Wenxuan Zhang, Weili Yang, Hanyang Ruan, Jian Gao, Zhen Wang
Summary: Internet-based cognitive behavioral therapy (ICBT) is an effective alternative to traditional cognitive behavioral therapy (CBT) for treating obsessive-compulsive disorder (OCD). The study found that CBT was more effective than therapist-guided ICBT (TG-ICBT), but the difference between CBT and unguided ICBT (UG-ICBT) was not significant. In terms of efficacy, all three interventions (CBT, TG-ICBT, and UG-ICBT) were superior to psychological placebo, waiting list, and pill placebo. Combination therapy of CBT with medication was more effective than the individual interventions.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Article
Psychiatry
Qihui Guo, Kaifeng Wang, Huiqin Han, Puyu Li, Jiayue Cheng, Junjuan Zhu, Zhen Wang, Qing Fan
Summary: Continuous theta burst stimulation (cTBS) over the bilateral supplementary motor area (SMA) is a safe and tolerable treatment for OCD patients, which significantly improves depression and anxiety levels but has limited effect on OCD symptoms.
EUROPEAN PSYCHIATRY
(2022)
Article
Psychiatry
Wenjie Gu, Qing Zhao, Chengmei Yuan, Zhenghui Yi, Min Zhao, Zhen Wang
Summary: Adverse childhood experiences are common in individuals with mental disorders, and the level of trauma affects the severity of these disorders. Emotional abuse is closely related to various mental disorders.
GENERAL PSYCHIATRY
(2022)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)