Article
Multidisciplinary Sciences
Erdem Pulcu, Kate E. A. Saunders, Catherine J. Harmer, Paul J. Harrison, Guy M. Goodwin, John R. Geddes, Michael Browning
Summary: The affective variability of bipolar disorder (BD) is different from that of borderline personality disorder (BPD), and lithium treatment increases the volatility of positive affect.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Clinical Neurology
Maurizio Pompili, Isabella Berardelli, Salvatore Sarubbi, Elena Rogante, Luca Germano, Giuseppe Sarli, Denise Erbuto, Ross J. Baldessarini
Summary: This study observed 260 patients with bipolar or major depressive disorder and found that lithium treatment reduced hospitalization rates and morbidity. Factors associated with hospitalization during lithium treatment included concurrent use of antipsychotic medication, suicide attempts during lithium treatment, lifetime substance abuse, and previous psychiatric hospitalization before starting lithium.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Gregory Jones, Carola Rong, Courtney M. Vecera, Christopher Gurguis, Roshan Chudal, Rushaniya Khairova, Edison Leung, Ana C. Ruiz, Lokesh Shahani, Marcus Zanetti, Rafael T. de Sousa, Geraldo Busatto, Jair Soares, Wagner F. Gattaz, Rodrigo Machado-Vieira
Summary: Lithium may play an important role in treating comorbid anxiety in bipolar disorder, both as adjunct and monotherapy. Lower doses of lithium may provide equivalent efficacy and enhance tolerability and compliance.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Medicine, General & Internal
Joseph F. Hayes, David P. J. Osborn, Emma Francis, Gareth Ambler, Laurie A. Tomlinson, Magnus Boman, Ian C. K. Wong, John R. Geddes, Christina Dalman, Glyn Lewis
Summary: This study developed a model to predict the risk of chronic kidney disease in patients with bipolar disorder following lithium treatment initiation, identifying individuals with a high-risk trajectory of kidney function. The model showed that individuals with characteristics such as younger age, female gender, and lower baseline eGFR were at increased risk of a poor eGFR trajectory, regardless of lithium duration and toxicity.
Review
Clinical Neurology
Konstantinos N. Fountoulakis, Mauricio Tohen, Carlos A. Zarate Jr
Summary: The study systematically reviewed the efficacy of lithium in different phases of Bipolar disorder, finding that it is effective in acute mania and maintenance treatment, either as monotherapy or in combination with other agents. However, its efficacy for acute bipolar depression requires combination with specific agents, and its efficacy in preventing depressive episodes remains unclear.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2022)
Article
Behavioral Sciences
Federica Pelacchi, Liliana Dell'Osso, Emi Bondi, Mario Amore, Andrea Fagiolini, Paolo Iazzetta, Daniela Pierucci, Manuela Gorini, Elisa Quarchioni, Alessandro Comandini, Enrica Salvatori, Agnese Cattaneo, Maurizio Pompili
Summary: This study is the first comparative documentation of the potential benefit of prolonged-release lithium in reducing lithium-induced tremor, a well-known adverse effect of lithium therapy. However, the study's results should be interpreted with caution due to the smaller sample size than planned.
BRAIN AND BEHAVIOR
(2022)
Article
Clinical Neurology
Mehmet Kemal Arikan, Guven Gunver, Reyhan Ilhan, Ozden Oksuz, Baris Metin
Summary: This study found that patients who did not respond to aripiprazole had significantly higher gamma power compared to aripiprazole responders. This suggests that gamma power may serve as a potential biomarker for unresponsiveness to aripiprazole treatment in patients with bipolar disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Maya Kuperberg, Ole Kohler-Forsberg, Alec P. Shannon, Nevita George, Sophie Greenebaum, Charles L. Bowden, Joseph R. Calabrese, Michael Thase, Richard C. Shelton, Melvin McInnis, Thilo Deckersbach, Mauricio Tohen, James H. Kocsis, Terence A. Ketter, Edward S. Friedman, Dan Iosifescu, Michael J. Ostacher, Louisa G. Sylvia, Susan L. McElroy, Andrew A. Nierenberg
Summary: The study found that patients with bipolar disorder have an increased cardiometabolic risk associated with symptom severity, and treatment with quetiapine can worsen cardiometabolic markers. The results highlight the importance of monitoring cardiometabolic risks during treatment.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Medicine, General & Internal
Theodoros Koutsomitros, Kenneth T. van der Zee, Olympia Evagorou, Teresa Schuhmann, Antonis C. Zamar, Alexander T. Sack
Summary: This open-label naturalistic study examined the feasibility, tolerability, and effectiveness of a repetitive transcranial magnetic stimulation (rTMS) protocol for treating patients with bipolar disorder type II. The study found that the rTMS treatment significantly reduced depression symptoms both immediately after treatment and one month later.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Yang-Chieh Brian Chen, Chih-Sung Liang, Liang-Jen Wang, Kuo-Chuan Hung, Andre F. Carvalho, Marco Solmi, Eduard Vieta, Ping-Tao Tseng, Pao -Yen Lin, Yu-Kang Tu, Chih-Wei Hsu, Edward Chia-Cheng Lai
Summary: This study investigates the association between serum valproic acid levels and risk of mood episode recurrence in bipolar disorder patients. The findings suggest that maintaining a serum valproic acid concentration between 50-74 μg/ml may be more effective in preventing acute mood episodes in patients with bipolar disorder compared to a concentration below 50 μg/ml.
Letter
Clinical Neurology
Mustafa Akkus
Summary: This case suggests that lithium-induced tardive dyskinesia may be reversible in a dose-dependent manner.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Psychiatry
Gao Zhihan, Sun Fengli, Lv Wangqiang, Shen Dong, Jin Weidong
Summary: The combination of lithium and lamotrigine has shown to be effective in improving mental symptoms and increasing response rates in patients with rapid-cycling bipolar disorder.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Clinical Neurology
Rukiye Tekdemir, Yavuz Selvi, Kursat Altinbas, Nadir Kocak
Summary: This study found that miRNAs play an important role in the pathogenesis of bipolar disorder and may serve as biomarkers for diagnosis and screening of the disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychiatry
Ole Kohler-Forsberg, Christopher Rohde, Andrew A. Nierenberg, Soren Dinesen Ostergaard
Summary: This study found an increased risk of osteoporosis in individuals with bipolar disorder. However, treatment with lithium was associated with a decreased risk of osteoporosis, suggesting that bone health should be prioritized in the clinical management of bipolar disorder and further research should be conducted on the potential bone-protective properties of lithium.
Review
Medicine, General & Internal
Javier Conejo-Galindo, Alejandro Sanz-Giancola, Miguel Angel Alvarez-Mon, Miguel A. Ortega, Luis Gutierrez-Rojas, Guillermo Lahera
Summary: Pregnancy and postpartum are critical periods with a high risk of relapse for bipolar disorder patients, with a particularly high risk of postpartum relapse. It is important to detect and treat decompensation in this period.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)