期刊
JOURNAL OF AFFECTIVE DISORDERS
卷 129, 期 1-3, 页码 167-174出版社
ELSEVIER
DOI: 10.1016/j.jad.2010.08.029
关键词
EEG asymmetry; Depression; Biological marker; Emotion
资金
- National Institutes of Health [R01-MH066902]
- National Alliance for Research on Schizophrenia and Depression (NARSAD)
Background: Although it has been argued that frontal electroencephalographic (EEG) asymmetry at rest may be a risk marker for major depressive disorder (MDD), it is unclear whether a pattern of relatively less left than right activity characterizes depressed individuals during emotional challenges. Examination of frontal asymmetry during emotion task manipulations could provide an assessment of the function of systems relevant for MDD, and test the limits of frontal EEG asymmetry as a marker of risk for depression. Methods: EEG data were assessed during a facial emotion task, wherein 306 individuals age 18-34 (31% male) with (n = 143) and without (n = 163) DSM-IV defined lifetime MDD made directed facial actions of approach (angry and happy) and withdrawal (afraid and sad) expressions. Results: Lifetime depressed individuals displayed less relative left frontal activity than never-depressed individuals during all facial expressions across four EEG reference montages, findings that were not due to emotional experience, facial expression quality, electromyographic (EMG) activity, or current depression status. Limitations: Although this was a sizable sample, only one emotion task was utilized. Conclusions: Results provide further support for frontal EEG asymmetry as a risk marker for MDD. (C) 2010 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据