Article
Anesthesiology
Remco Vellinga, Laura N. Hannivoort, Michele Introna, Daan J. Tourw, Anthony R. Absalom, Douglas J. Eleveld, Michel M. R. F. Struys
Summary: The Eleveld propofol PK-PD model was prospectively validated in children, adults, older subjects, and obese adults undergoing general anaesthesia. The results showed high predictive precision and low bias in arterial plasma concentrations and BIS predictions when used in TCI in clinical anaesthesia practice.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Article
Otorhinolaryngology
Anupam Kanodia, Deepankar Srigyan, Kapil Sikka, Aashish Choudhary, Avinash Choudekar, Saurabh Mittal, Shweta Arun Bhopale, Lalit Dar, Alok Thakar
Summary: Topical lignocaine application in the oropharynx improves patient comfort during COVID-19 testing, but does not affect the viral load of SARS-CoV-2 in the samples collected.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Anesthesiology
Cyrille Robert, Anne Soulier, Didier Sciard, Guillaume Dufour, Corinne Alberti, Priscilla Boizeau, Marc Beaussier
Summary: This study aimed to compare the cognitive status of patients after surgery with desflurane or propofol anesthesia at an Aldrete score of >= 9. The results showed that cognitive function was significantly reduced in the DSST test for the desflurane group, but the combined Z scores at Aldrete score of >= 9 did not show a significant difference between desflurane and propofol groups.
BMC ANESTHESIOLOGY
(2021)
Article
Gastroenterology & Hepatology
Jakob Garbe, Stephan Eisenmann, Jan W. Kantelhardt, Florian Duenninghaus, Patrick Michl, Jonas Rosendahl
Summary: This study aimed to differentiate consciousness in endoscopic propofol sedation using EEG parameters, with complexity and optimised frequency domain parameters yielding the best results. While these findings are not sufficient for clinical application, prediction capability may be increased with further optimisation and modelling.
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2021)
Article
Anesthesiology
Thomas W. Schnider, Charles F. Minto
Summary: Variability is high in predicted propofol concentrations during clinical anesthesia, and improving pharmacokinetic models is unlikely to reduce variability in target anesthetic concentrations across patients in clinical practice.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Medicine, General & Internal
Mahmoud Ahmed, Yamini Krishna, Petya Popova, Rose Herbert, Gediminas Sidaras, Anshoo Choudhary, Stephen B. B. Kaye
Summary: This study examined the impact of low-dose propofol sedation on patient reported outcome measures (PROMS) during cataract surgery. The study found that the use of low-dose propofol was associated with reduced pain, needle recall, and blood pressure. The results suggest that propofol can be an effective sedation method for cataract surgery.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Xi Zhao, Ze-qing Huang
Summary: This study aims to evaluate the efficacy and safety of propofol on postoperative cognitive dysfunction after general anesthesia, providing valuable information for clinicians and health policy makers.
SYSTEMATIC REVIEWS
(2021)
Article
Anesthesiology
Yu-Long Wang, Lu Wang, Wei Xu, Miao He, Hui Dong, Huan-Ying Shi, Yong-Quan Chen, Zhi-Li Huang
Summary: This study found that the activity of the paraventricular thalamus (PVT) is closely related to consciousness transitions during propofol anesthesia. Inhibition of PVT neurons promotes the loss and recovery of consciousness, while stimulation of PVT neurons has the opposite effect. The results provide a potential neuroanatomical target for controlling consciousness to reduce anesthesia dose requirements and side effects.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Review
Biochemistry & Molecular Biology
Aida Raigon Ponferrada, Jose Luis Guerrero Orriach, Juan Carlos Molina Ruiz, Salvador Romero Molina, Aurelio Gomez Luque, Jose Cruz Manas
Summary: Breast cancer is the leading cause of mortality in women, and the clinical and morphological heterogeneity of breast tumors has led to diversity in staging and classification systems. Surgical treatment is crucial for managing breast cancer patients, while the use of anesthetic and analgesic agents during surgery may impact the survival and progression of the disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Anesthesiology
Andrew E. Hudson
Summary: A study has found that 11% of young adults were able to respond to auditory commands when neuromuscular blocking drugs were prevented from reaching one arm using the isolated forearm technique. This occurrence was common in both male and female patients who underwent anesthesia following usual clinical practice in 10 countries, but it was significantly more common in women. Further understanding of the experiences of these patients is crucial for our understanding of the state of general anesthesia.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Review
Medicine, General & Internal
Song Chen, Jie Xiang, Yan Ji
Summary: This systematic review aimed to evaluate the efficacy of articaine compared to lignocaine for infiltration anaesthesia in primary molar extractions. The analysis of six included studies showed no difference in pain scores between articaine and lignocaine with single buccal infiltration. However, when comparing buccal with palatal/lingual infiltration, articaine was found to significantly reduce pain scores compared to lignocaine.
PAKISTAN JOURNAL OF MEDICAL SCIENCES
(2022)
Article
Computer Science, Interdisciplinary Applications
Jose M. Gonzalez-Cava, Fredrik Bagge Carlson, Olof Troeng, Anton Cervin, Klaske van Heusden, Guy A. Dumont, Kristian Soltesz
Summary: This study compares the performance limitations of using a filtered PID controller and a high-order Youla controller in hypnosis regulation in anaesthesia. It was found that designing individual-specific controllers resulted in similar frequency response characteristics for both types of controllers when optimizing for the same performance objective.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2021)
Article
Multidisciplinary Sciences
Thomas F. Varley, Vanessa Denny, Olaf Sporns, Alice Patania
Summary: Research has shown that the vividness of conscious experience is related to brain dynamics, with propofol and ketamine producing different subjective states despite both being anaesthetics. Using different methods, it was found that the awake condition had the richest structure, propofol condition had the most dissimilar dynamics, and ketamine condition combined aspects of both, being less complex than awake but above propofol in most measures. This study provides deeper insights than traditional point-measures of complexity.
ROYAL SOCIETY OPEN SCIENCE
(2021)
Article
Psychiatry
Chen Chen, Yuxue Wang, Jin Rao, Weixiang Tang, Weiwei Wu, Yuanhai Li, Guanghong Xu, Weiwei Zhong
Summary: The study compared the differences in attention network impairment after surgery in women receiving propofol versus sevoflurane general anaesthesia. The results showed that propofol impaired orienting and alerting networks more than sevoflurane in middle-aged women, while sevoflurane showed more residual impairment of the executive control network.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Surgery
Yue Sun, Jianhui Zhao, Wenli Guo, Hailing Mu, Ying Zhao, Yaping Xie, Chen Yang, Yao Lu
Summary: This prospective study investigated the effect of intravenous lidocaine on tourniquet hypertension in patients undergoing ambulatory arthroscopy under general anaesthesia. The results showed that lidocaine significantly reduced the incidence of tourniquet hypertension compared to normal saline. In addition, lidocaine also had beneficial effects on postoperative pain and recovery.
Article
Clinical Neurology
Veronica Galvez, Phern-Chern Tor, Adriana Bassa, Dusan Hadzi-Pavlovic, Ross MacPherson, Mincho Marroquin-Harris, Colleen K. Loo
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2016)
Article
Neurosciences
Tjeerd W. Boonstra, Stevan Nikolin, Ann-Christin Meisener, Donel M. Martin, Colleen K. Loo
FRONTIERS IN HUMAN NEUROSCIENCE
(2016)
Article
Clinical Neurology
Donel M. Martin, Kevin Yeung, Colleen K. Loo
JOURNAL OF AFFECTIVE DISORDERS
(2016)
Article
Clinical Neurology
Veronica Galvez, Adrienne Li, Cristal Oxley, Susan Waite, Nick De Felice, Dusan Hadzi-Pavlovic, Divya Kumar, Andrew C. Page, Geoff Hooke, Colleen K. Loo
JOURNAL OF AFFECTIVE DISORDERS
(2016)
Article
Behavioral Sciences
Phern-Chern Tor, Veronica Galvez, James Goldstein, Duncan George, Colleen K. Loo
Article
Behavioral Sciences
Divya Rani Kumar, Hank Ke Han, John Tiller, Colleen K. Loo, Donel M. Martin
Review
Psychology, Clinical
Donel M. Martin, Shawn M. McClintock, Jane Forster, Colleen K. Loo
NEUROPSYCHOLOGY REVIEW
(2016)
Letter
Psychiatry
Paul Glue, Colleen Loo, Anthony Rodgers, Veronica Galvez, Andrew A. Somogyi, Philip B. Mitchell
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
(2017)
Article
Psychiatry
S. Bai, V. Galvez, S. Dokos, D. Martin, M. Bikson, C. Loo
EUROPEAN PSYCHIATRY
(2017)
Article
Clinical Neurology
Alaa M. Al-Kaysi, Ahmed Al-Ani, Colleen K. Loo, Tamara Y. Powell, Donel M. Martin, Michael Breakspear, Tjeerd W. Boonstra
JOURNAL OF AFFECTIVE DISORDERS
(2017)
Editorial Material
Behavioral Sciences
Veronica Galvez, Colleen K. Loo
Article
Psychiatry
Karma Karolina Kedzior, Maria Schuchinsky, Imke Gerkensmeier, Colleen Loo
JOURNAL OF PSYCHIATRIC RESEARCH
(2017)
Article
Psychiatry
Ian M. Anderson, Andrew Blamire, Tim Branton, Ross Clark, Darragh Downey, Graham Dunn, Andrew Easton, Rebecca Elliott, Clare Elwell, Katherine Hayden, Fiona Holland, Salman Karim, Colleen Loo, Jo Lowe, Rajesh Nair, Timothy Oakley, Antony Prakash, Parveen K. Sharma, Stephen R. Williams, R. Hamish McAllister-Williams
Review
Clinical Neurology
Andre R. Brunoni, Adriano H. Moffa, Bernardo Sampaio-Junior, Veronica Galvez, Colleen K. Loo
Article
Psychiatry
Veronica Galvez, Stevan Nikolin, Kerrie-Anne Ho, Angelo Alonzo, Andrew A. Somogyi, Colleen K. Loo
COMPREHENSIVE PSYCHIATRY
(2017)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)