Article
Medicine, General & Internal
Charles L. Raison, Gerard Sanacora, Joshua Woolley, Keith Heinzerling, Boadie W. Dunlop, Randall T. Brown, Rishi Kakar, Michael Hassman, Rupal P. Trivedi, Reid Robison, Natalie Gukasyan, Sandeep M. Nayak, Xiaojue Hu, Kelley C. O'Donnell, Benjamin Kelmendi, Jordan Sloshower, Andrew D. Penn, Ellen Bradley, Daniel F. Kelly, Tanja Mletzko, Christopher R. Nicholas, Paul R. Hutson, Gary Tarpley, Malynn Utzinger, Kelsey Lenoch, Kasia Warchol, Theraysa Gapasin, Mike C. Davis, Courtney Nelson-Douthit, Steffanie Wilson, Carrie Brown, William Linton, Stephen Ross, Roland R. Griffiths
Summary: This study aims to evaluate the antidepressant effects and safety of a single dose of psilocybin in patients with major depressive disorder. The results show that psilocybin treatment is associated with a significant reduction in depressive symptoms and functional disability, without serious adverse events.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Substance Abuse
Jasper A. J. Smits, Michael J. Zvolensky, David Rosenfield, Richard A. Brown, Michael W. Otto, Christina D. Dutcher, Santiago Papini, Slaton Z. Freeman, Annabelle DiVita, Alex Perrone, Lorra Garey
Summary: This study tested the efficacy of an exercise program on smoking cessation in individuals with high anxiety sensitivity. The personalized exercise intervention group showed significantly higher abstinence rates at 6-month follow-up compared to the control group. However, anxiety sensitivity decreased in both groups without any significant difference between them.
Article
Medicine, General & Internal
M. Ishrat Husain, Imran B. Chaudhry, Ameer B. Khoso, Tayyeba Kiran, Nawaz Khan, Farooq Ahmad, John Hodsoll, M. Omair Husain, Haider A. Naqvi, Asad T. Nizami, Nasim Chaudhry, Hazrat A. Khan, Fareed Minhas, Jeffrey H. Meyer, Moin A. Ansari, Benoit H. Mulsant, Nusrat Husain, Allan H. Young
Summary: This study aimed to assess the efficacy and tolerability of adjunctive simvastatin in reducing depressive symptoms in treatment-resistant depression (TRD). The results showed no significant differences between the simvastatin group and the placebo group in primary and secondary outcomes, and there were also no significant differences in adverse effects between the two groups. Therefore, simvastatin did not provide additional therapeutic benefit for depressive symptoms in TRD.
Review
Clinical Neurology
Huan Wang, Mengdi Jin, Mengtong Xie, Yuqing Yang, Fengyu Xue, Weizhen Li, Min Zhang, Zhijun Li, Xinwei Li, Ningning Jia, Yane Liu, Xingyao Cui, Guoyan Hu, Lin Dong, Guixia Wang, Qiong Yu
Summary: New research supports the use of an integrated approach to treating depression, including lifestyle modifications. This meta-analysis investigated the relationship between various antioxidant supplements and depression, finding that they have a positive effect on both depression and anxiety states.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Medicine, General & Internal
Michael G. Rizzo Jr, Joseph P. Costello, Dylan Luxenburg, Jacob L. Cohen, Nicolas Alberti, Lee D. Kaplan
Summary: Both augmented reality (AR) and virtual reality (VR) have been increasingly used in medicine, and this study aimed to investigate the effect of AR on patients' preoperative anxiety. The randomized clinical trial found that the use of AR decreased preoperative anxiety compared to traditional perioperative education, but had no significant effect on postoperative anxiety, pain levels, or narcotic use.
Article
Multidisciplinary Sciences
Matilde Roda, Marco Pellegrini, Natalie Di Geronimo, Aldo Vagge, Michela Fresina, Costantino Schiavi
Summary: This meta-analysis found no convincing evidence supporting the efficacy of binocular treatment as an alternative to conventional patching. Therefore, binocular treatment cannot fully replace traditional treatment but can be considered a valid complementary therapy in peculiar cases. Further studies are required to determine whether more engaging therapies and new treatment protocols are more effective.
Article
Integrative & Complementary Medicine
Diogo Amorim, Irma Brito, Armando Caseiro, Joao Paulo Figueiredo, Andre Pinto, Ines Macedo, Jorge Machado
Summary: This study found that both acupuncture and electroacupuncture are effective in treating anxiety, leading to improvements in anxiety levels. The treatments were found to be independent of anxiolytic medication.
COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
(2022)
Review
Psychiatry
Ling Li Leng, Xi Can Yin, Siu Man Ng
Summary: This meta-analysis found that mindfulness-based interventions (MBIs) have significant effects on perinatal depression and anxiety, especially in low- and middle-income countries where mental health care is less available. MBIs can complement and broaden the range of effective interventions for perinatal mental health.
COMPREHENSIVE PSYCHIATRY
(2023)
Article
Medicine, General & Internal
Xuan Yin, Wei Li, Tingting Liang, Bing Lu, Hongyu Yue, Shanshan Li, Victor W. Zhong, Wei Zhang, Xia Li, Shuang Zhou, Yiqun Mi, Huangan Wu, Shifen Xu
Summary: In this randomized clinical trial, electroacupuncture (EA) treatment significantly improved sleep quality in patients with comorbid insomnia and depression compared to sham acupuncture or standard care at week 8 and maintained the improvement at week 32.
Article
Psychology, Clinical
Laura E. Kunst, Joyce Maas, Anton J. L. M. Balkom, Marcel A. L. M. Assen, Brenda Kouwenhoven, Marrie H. J. Bekker
Summary: Although the autonomy-enhancing treatment (AET) did not show superior effectiveness compared to cognitive behavioral therapy (CBT) in broader outcome measures, it did confirm the effectiveness of AET as a treatment option for anxiety disorders. The study suggests that AET and CBT have similar effects in reducing anxiety symptoms.
DEPRESSION AND ANXIETY
(2022)
Article
Integrative & Complementary Medicine
Katayon Vakilian, Mehrnoush Ghaemmaghami, Narges Sheikhganbari, Fatemeh Shabani, Masoomeh Vahedi
Summary: Auriculotherapy was effective in reducing labor anxiety, particularly in reducing state and trait anxiety. There were no significant differences in delivery mode, newborns' weight, and Apgar score between the two groups, and no adverse outcomes were observed.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE
(2022)
Article
Psychiatry
Viktoriya L. Nikolova, Anthony J. Cleare, Allan H. Young, James M. Stone
Summary: This study aims to assess the acceptability and tolerability of probiotics as adjunctive treatment for major depressive disorder (MDD) and estimate its treatment effect on clinical symptoms. The results showed that the probiotic group had better improvement in depressive and anxiety symptoms compared to the placebo group, and the treatment approach was well accepted and tolerated.
Article
Clinical Neurology
Carolyn A. Schniering, Danielle Einstein, Jessica J. L. Kirkman, Ronald M. Rapee
Summary: This study evaluated the efficacy of an online cognitive behavior therapy program for adolescents with comorbid anxiety and mood disorders. The results showed that treated participants experienced greater reduction in the number of disorders and were more likely to remit from all anxiety and mood disorders compared to the waiting participants. However, there was no significant improvement in life interference.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Chemistry, Medicinal
Mengyue Fu, Shi Chen, Rui Xu, Jie Chen, Xuehan Chen, Wanxia Gan, He Huang, Guangyou Duan
Summary: This study aimed to explore the effects of intravenous analgesia using tramadol on postoperative depression, anxiety, and sleep in women undergoing abdominal endoscopic surgery. The results showed that intravenous analgesia with tramadol can effectively improve postoperative depression and sleep, with no impact on anxiety state.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Article
Clinical Neurology
Michelle L. Miller, Joseph F. McGuire
Summary: This systematic review and meta-analysis examined the efficacy of evidence-based treatments for anxiety-related disorders on intolerance of uncertainty (IU), finding that these treatments have significant therapeutic effects on IU. The study also found that improvements in IU corresponded with improvements in anxiety symptom severity, highlighting the importance of targeting IU in the treatment of anxiety-related disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Neil McNaughton, Charles Swart, Phoebe Neo, Vanessa Bates, Paul Glue
JOURNAL OF AFFECTIVE DISORDERS
(2013)
Letter
Psychology, Clinical
Chris Gale, Paul Glue, Yoram Barak
PSYCHOLOGICAL MEDICINE
(2019)
Article
Clinical Neurology
Paul Glue, Shona Neehoff, Amandine Sabadel, Lucy Broughton, Martin Le Nedelec, Shabah Shadli, Neil McNaughton, Natalie J. Medlicott
JOURNAL OF PSYCHOPHARMACOLOGY
(2020)
Article
Clinical Neurology
Dylan Truppman Lattie, Hayley Nehoff, Shona Neehoff, Andrew Gray, Paul Glue
Summary: Ketamine demonstrates rapid and dose-related anxiolytic effects in treatment-resistant anxiety disorders, as shown by reductions in anxiety symptoms on the Fear Questionnaire and State Anxiety Inventory. Maintenance therapy with ketamine further reduces anxiety symptoms over time, suggesting its therapeutic potential in phobic states.
JOURNAL OF PSYCHOPHARMACOLOGY
(2021)
Review
Pharmacology & Pharmacy
Paul Glue, Bruce Russell, Natalie J. Medlicott
Summary: This structured review examined the effects of ketamine formulation and route of administration on its pharmacokinetics, safety, and tolerability, in order to identify characteristics and routes that might minimize side effects. Formulations that maximize first pass metabolism and delay T-max are better tolerated and safer.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2021)
Article
Psychiatry
Jessie Lenagh-Glue, John Dawson, Johnnie Potiki, Anthony J. O'Brien, Katey Thom, Heather Casey, Paul Glue
Summary: Advance directives are advocated to promote supported decision-making and compliance with the United Nations Convention on the Rights of Persons with Disabilities. Integration of advance directives into mental health law, along with supportive practices and policies, is necessary for their effective use.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2023)
Letter
Clinical Neurology
Aindrea Brown, Paul Glue
Article
Multidisciplinary Sciences
Shabah M. Shadli, Lynne C. Ando, Julia McIntosh, Veema Lodhia, Bruce R. Russell, Ian J. Kirk, Paul Glue, Neil McNaughton
Summary: The study suggests that the theoretical biomarker GCSR can help diagnose and redefine psychiatric disorders. Research shows that anxiolytic drugs reduce GCSR and correlate with anxiety scores.
SCIENTIFIC REPORTS
(2021)
Article
Psychiatry
Ben Stegmann, Chris Gale, Paul Glue
Summary: This study retrospectively analyzed patients receiving maintenance ECT in a specific region of New Zealand, examining the treatment patterns and its impact on hospitalization. The results showed that the use of maintenance ECT in the region is consistent with national trends, and patients with mood disorders experienced a greater reduction in hospitalization time during maintenance ECT.
AUSTRALASIAN PSYCHIATRY
(2023)
Article
Criminology & Penology
Xiaohui I. I. Lin, Thomas White, Andrew R. R. Gray, Paul Glue
Summary: Violence risk prediction in forensic mental health care settings is crucial for managing violence. Previous studies have suggested that the Health of the Nation Outcome Scales-Secure (HoNOS-secure) may have some predictive validity for violence. This retrospective cohort study examines the predictive validity of HoNOS-secure scores for inpatient violence in a medium-secure forensic psychiatric ward. While the total and subscale scores were not significant predictors, item-level analysis demonstrated associations between specific items and violence. Future studies could consider pooling data, extending follow-up periods, and adopting a prospective design.
JOURNAL OF FORENSIC PSYCHIATRY & PSYCHOLOGY
(2023)
Review
Pharmacology & Pharmacy
Elizabeth Whittaker, Alisher R. Dadabayev, Sonalee A. Joshi, Paul Glue
Summary: Ketamine shows potential efficacy in treating anxiety spectrum disorders, especially social anxiety disorder. Higher doses of ketamine may be more effective in improving anxiety symptoms than lower doses. Ketamine maintenance therapy provides sustained anxiolytic effects and improves social or work functioning.
THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY
(2021)
Article
Pharmacology & Pharmacy
Paul Glue, Natalie J. Medlicott, Shona Neehoff, Peter Surman, Fred Lam, Noelyn Hung, Cheung-tak Hung
THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY
(2020)
Article
Education, Special
T. Patterson, C. M. Rapsey, P. Glue
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH
(2013)
Article
Medicine, General & Internal
William Shelker, Peter Herbison, Alison Belton, Paul Glue
NEW ZEALAND MEDICAL JOURNAL
(2013)
Letter
Medicine, General & Internal
Paul Glue, Chris Gale
NEW ZEALAND MEDICAL JOURNAL
(2013)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)