Article
Clinical Neurology
Kelly A. Ryan, Peisong Han, Yuhua Zhang, David F. Marshall, Anastasia K. Yocum, Melvin G. McInnis, Sebastian Zollner
Summary: Individuals with bipolar disorder tend to have higher neuroticism and lower extraversion and consciousness compared to healthy controls. Personality traits show only small changes over time, with neuroticism being the only trait associated with changes in mood state. Other factors beyond mood changes may influence changes in personality traits.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Psychiatry
Lauro Estivalete Marchionatti, Thyago Antonelli-Salgado, Isadora Nunes Erthal, Savio Luiz Santos Lopes, Luiza Silveira Lucas, Diego Barreto Reboucas, Ives Cavalcante Passos
Summary: This systematic review on the impact of disease progression in the treatment of bipolar disorder patients found that efficacy decreases with clinical progression, supporting early intervention. However, tailored recommendations cannot be made based on disease stages currently, highlighting the need for further research.
PSYCHIATRY RESEARCH
(2022)
Article
Psychology, Clinical
Brett D. M. Jones, Brisa S. Fernandes, M. Ishrat Husain, Abigail Ortiz, Tarek K. Rajji, Daniel M. Blumberger, Meryl A. Butters, Ariel G. Gildengers, Tatiana Shablinski, Aristotle Voineskos, Benoit H. Mulsant
Summary: This study aims to explore the relationships among clinical characteristics of bipolar disorder (BD), cognitive dysfunction, and aging. The results support both an early impairment model and an accelerated aging model, indicating that different cognitive domains are affected differently by BD and aging.
PSYCHOLOGICAL MEDICINE
(2023)
Review
Clinical Neurology
Jason Ng, Joshua D. Rosenblat, Leanna M. W. Lui, Kayla M. Teopiz, Yena Lee, Orly Lipsitz, Rodrigo B. Mansur, Nelson B. Rodrigues, Flora Nasri, Hartej Gill, Danielle S. Cha, Mehala Subramaniapillai, Roger C. Ho, Bing Cao, Roger S. McIntyre
Summary: The review and synthesis of existing literature on functional outcomes with ketamine/esketamine treatment in adults with treatment-resistant depression suggest mixed results across different functional measures, with improvements in general psychosocial functioning apparent. Future research is needed to explore the association between symptomatic improvement and functional improvement in TRD.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Clinical Neurology
Silvana Zito, Guido Nosari, Alessandro Pigoni, Chiara Moltrasio, Giuseppe Delvecchio
Summary: This review examines the relationship between testosterone levels and mood disorders, specifically major depressive disorder and bipolar disorder. The results from the reviewed studies were conflicting, with some showing low levels of testosterone in both disorders, while others showed a mixed picture of reduced, increased or no difference in testosterone levels. Overall, testosterone may serve as a useful biomarker in mood disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Gail I. S. Harmata, Ercole John Barsotti, Lucas G. Casten, Jess G. Fiedorowicz, Aislinn Williams, Joseph J. Shaffer, Jenny Gringer Richards, Leela Sathyaputri, Samantha L. Schmitz, Gary E. Christensen, Jeffrey D. Long, Marie E. Gaine, Jia Xu, Jake J. Michaelson, John A. Wemmie, Vincent A. Magnotta
Summary: This study found that the cerebellar cortex is smaller in individuals with bipolar disorder (BD). The study also suggests that external factors, such as sedatives and childhood experiences, may influence cerebellum structure in BD. Future research should consider these variables for consistent findings.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Yuan-Yuan Wang, Yuan Feng, Meng Fang, Chengwei Guo, Gabor S. Ungvari, Brian J. Hall, Gang Wang, Yu-Tao Xiang
Summary: The study compared the screening abilities and consistency between HCL-33 and HCL-33-EA, with results showing HCL-33-EA outperforming HCL-33 in sensitivity and HCL-33 having higher specificity. There was significant screening consistency between the two scales.
FRONTIERS IN PSYCHIATRY
(2021)
Review
Clinical Neurology
Beatriz Corte-Real, Rodrigo Saraiva, Catarina Rodrigues Cordeiro, Benicio N. Frey, Flavio Kapczinski, Taiane de Azevedo Cardoso
Summary: The study aimed to investigate whether atypical antipsychotics (AA) can induce mania in mood disorders. A systematic review and meta-analysis showed that AA-induced mania is rare and the use of AA is more effective in preventing the development of mania compared to placebo.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Maria Faurholt-Jepsen, Jonas Busk, Darius Adam Rohani, Mads Frost, Morten Lindberg Tonning, Jakob Eyvind Bardram, Lars Vedel Kessing
Summary: This study found that analyzing mobile location data can differentiate between patients with BD and UD, and mobility patterns can serve as a promising digital diagnostic marker.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Gianluca Sesso, Annarita Milone, Flavia Drago, Valentina Viglione, Stefano Berloffa, Silvia Boldrini, Nina Loriaux, Elena Valente, Agnese Molesti, Francesca Placini, Anna Rita Montesanto, Simone Pisano, Gabriele Masi
Summary: A novel self-report questionnaire, the RIPoSt-Y, was developed and validated for assessing emotional dysregulation in adolescents, showing good reliability and validity in both clinical and non-clinical samples. The questionnaire consists of 31 items with three subscales covering affective instability, emotional reactivity, and interpersonal sensitivity. The study findings support the potential of this questionnaire in characterizing emotional dysregulation in youths.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Mario Simjanoski, Karen Jansen, Thaise Campos Mondin, Fernanda Pedrotti Moreira, Igor Soares Vieira, Ricardo Azevedo da Silva, Luciano Dias de Mattos Souza, Benicio N. Frey, Taiane de Azevedo Cardoso, Flavio Kapczinski
Summary: The study aimed to assess the differences in subjective cognitive dysfunction between major depressive disorder (MDD) and recently diagnosed Bipolar Disorder (BD) across euthymia and mood episodes. Results showed higher subjective cognitive dysfunction in individuals recently diagnosed with BD compared to those with MDD during euthymia.
PSYCHIATRY RESEARCH
(2021)
Article
Clinical Neurology
Anastasia K. Yocum, Yuqi Zhai, Melvin G. McInnis, Peisong Han
Summary: The study found that individuals with bipolar disorder experienced greater impact from the SAR-Cov-2 pandemic and lockdown, particularly in disruptions to routines, income/employment, social support, and pandemic-related stress. While these impacts improved over time, individuals with bipolar disorder recovered more slowly and to a lesser extent compared to healthy controls. Comparisons between pre- and post-pandemic periods showed a modest but significant increase in mood severity in healthy controls, while no significant differences were observed in individuals with bipolar disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Maria Faurholt-Jepsen, Jonas Busk, Maj Vinberg, Ellen Margrethe Christensen, Helgathorarinsdottir, Mads Frost, Jakob E. Bardram, Lars Vedel Kessing
Summary: The study found differences in location data between patients with bipolar disorder and healthy control individuals, as well as variations in location data between different affective states within bipolar disorder. Utilizing smartphone-based location data may be a promising measure to monitor illness and illness activity in patients with bipolar disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Maria Faurholt-Jepsen, Jonas Busk, Jakob Eyvind Bardram, Sharleny Stanislaus, Mads Frost, Ellen Margrethe Christensen, Maj Vinberg, Lars Vedel Kessing
Summary: This study found a positive association between mood instability and activity/energy instability in patients with bipolar disorder. These instabilities were also associated with stress, quality of life, and functioning. The findings highlight the importance of monitoring and identifying inter-episodic fluctuations in symptoms for clinical management.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Health Care Sciences & Services
Sunhae Kim, Hye-Kyung Lee, Kounseok Lee
Summary: Using machine learning analysis, participants' mood symptoms can be classified and predicted more accurately. The prediction results for depressive symptoms and hypomanic symptoms vary across different methods used.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Psychology, Clinical
Ian M. Anderson, R. Hamish McAllister-Williams, Darragh Downey, Rebecca Elliott, Colleen Loo
Summary: This study examined the impact of remission status on cognitive function in depressed patients 4 months after a course of ECT. Remitted patients showed improved subjective memory and verbal memory recall, while other aspects of cognitive function were not significantly influenced by remission status. Self-rated memory may be a useful tool to monitor the effects of ECT on longer-term memory.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Psychiatry
Patricia A. Gooding, Daniel Pratt, Yvonne Awenat, Richard Drake, Rachel Elliott, Richard Emsley, Charlotte Huggett, Steven Jones, Navneet Kapur, Fiona Lobban, Sarah Peters, Gillian Haddock
Article
Health Care Sciences & Services
Fiona Lobban, Nadia Akers, Duncan Appelbe, Rossella Iraci Capuccinello, Lesley Chapman, Lizzi Collinge, Susanna Dodd, Sue Flowers, Bruce Hollingsworth, Mahsa Honary, Sonia Johnson, Steven H. Jones, Ceu Mateus, Barbara Mezes, Elizabeth Murray, Katerina Panagaki, Naomi Rainford, Heather Robinson, Anna Rosala-Hallas, William Sellwood, Andrew Walker, Paula R. Williamson
HEALTH TECHNOLOGY ASSESSMENT
(2020)
Editorial Material
Clinical Neurology
Jasper Palmier-Claus, Fiona Lobban, Warren Mansell, Steve Jones, Elizabeth Tyler, Christopher Lodge, Samantha Bowe, Alyson Dodd, Kim Wright
Article
Clinical Neurology
Barbara Mezes, Fiona Lobban, Deborah Costain, Damien Longson, Steven H. Jones
Summary: Research compared psychological factors in personal recovery and clinical recovery among patients with bipolar disorder, finding that adaptive coping was associated with better recovery outcomes, while negative self-appraisals and dysfunctional attitudes were linked to poorer outcomes. Differences in psychological factors influencing personal and clinical recovery suggest the importance of individualized, person-centered therapeutic approaches.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Clinical Neurology
Glorianna Jagfeld, Fiona Lobban, Paul Marshall, Steven H. Jones
Summary: This study uncovered personal recovery experiences in bipolar disorder through two analysis approaches and proposed the POETIC personal recovery framework. The framework synthesizes all CHIME processes with a focus on addressing difficulties, losses, and tensions in the recovery process. However, the lack of diversity among study participants, mostly middle-aged, female, Western participants, limits the generalizability of the findings.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Kim Wright, Alyson L. Dodd, Fiona C. Warren, Antonieta Medina-Lara, Barnaby Dunn, Julie Harvey, Mahmood Javaid, Steven H. Jones, Christabel Owens, Rod S. Taylor, Deborah Duncan, Alexandra Newbold, Shelley Norman, Faith Warner, Thomas R. Lynch
Summary: The study conducted a feasibility study of the ThrIVe-B program for bipolar mood fluctuations, with promising recruitment and retention rates. Results indicated potential benefits of the intervention arm over the control arm on some outcome measures, despite lower attendance rates. Changes to the therapy program may be needed to improve engagement.
INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS
(2021)
Article
Psychiatry
Ian M. Anderson
Summary: There are highly polarized views on the effectiveness of Electroconvulsive therapy (ECT) for depression. While some studies have found ECT to be an effective treatment, a recent review questions the quality of these studies and suggests that the use of ECT should be suspended due to its risks.
Article
Clinical Neurology
Julia N. Lukacs, Anna Chiara Sicilia, Steven Jones, Guillermo Perez Algorta
Summary: The study found that gist values mediated the effect of categorical gist on risk taking, while impulsivity moderated risk taking but manic symptoms did not. Therefore, FTT may play an important role in the risk-taking behaviors of individuals with Bipolar disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychology, Clinical
Greg Murray, Neil Thomas, Erin E. Michalak, Steven H. Jones, Sara Lapsley, Steven J. Bowe, Fiona Foley, Kathryn Fletcher, Tania Perich, Sheri L. Johnson, Sue Cotton, Lesley Berk, Cathrine Mihalopoulos, Michael Kyrios, Michael Berk
Summary: This study found that an online mindfulness-based intervention was not superior to psychoeducation for improving quality of life in late-stage bipolar disorder patients. However, both interventions were feasible, acceptable, and safe, suggesting the need for future efforts to improve access to novel therapies for this population. Adaptive interventions targeting more symptomatic individuals may be beneficial in the future.
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY
(2021)
Article
Neurosciences
Sofia Isabel Ribeiro Pereira, Maria-Efstratia Tsimpanouli, Isabel Hutchison, Jules Schneider, Ian M. Anderson, Martyn McFarquhar, Rebecca Elliott, Penelope A. Lewis
Summary: The study aimed to examine the impact of targeted memory reactivation (TMR) during slow wave sleep (SWS) on neural processing of emotional memories. The results showed that cueing neutral stimuli increased activity in the orbitofrontal cortex (OFC), while cueing negative stimuli led to decreased OFC activation. In addition, the effect of cueing on amygdala activation was modulated by time spent in REM sleep.
Article
Psychiatry
Steven Jones, Dimitrinka Atanasova, Susanna Dodd, Susan Flowers, Anna Rosala-Hallas, Heather Robinson, Elena Semino, Fiona Lobban
Summary: This study reported on the usage of online forums during the Relatives Education and Coping Toolkit (REACT) trial. The findings showed that only a proportion of relatives actively engaged with the forum, but they represented a wide range of age and sociodemographic groups. Relatives used the forum primarily to seek support, share their experiences, and manage the challenges they faced. This highlights the potential value of easily accessible, moderated, peer-supported forums for relatives.
JMIR MENTAL HEALTH
(2022)
Review
Psychology, Clinical
Paul Marshall, Keith Sansom, Glorianna Jagfeld, Steven Jones, Fiona Lobban
Summary: This review aimed to synthesise qualitative evidence regarding carers' perspectives of supporting someone who has experienced suicidal behaviour. The initial reactions of carers to suicidal behaviour included profound anxiety and intensive monitoring. Carers also reported significant challenges in providing effective interpersonal support and accessing appropriate help.
PSYCHOLOGY AND PSYCHOTHERAPY-THEORY RESEARCH AND PRACTICE
(2023)
Article
Psychology, Clinical
Mark Clamp, Steven Jones, Mark Limmer
Summary: Instances of self-harm among young people are increasing, posing a challenge for healthcare and mental health services. A study conducted with young people who had received therapy for self-harm showed that a sense of control over their lives was a common goal in therapy. The findings also highlighted the importance of understanding and reclaiming control for a positive therapy experience and success.
COUNSELLING & PSYCHOTHERAPY RESEARCH
(2023)
Article
Medical Informatics
Glorianna Jagfeld, Fiona Lobban, Chloe Humphreys, Paul Rayson, Steven Huntley Jones
Summary: The study analyzed online support forum posts to understand the experience of personal recovery in bipolar disorder, using the POETIC framework. It identified three main domains of focus in personal recovery: purpose and meaning, connectedness, and empowerment. This study provides valuable insights for carers to better understand and support individuals with bipolar disorder.
JMIR MEDICAL INFORMATICS
(2023)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)