Article
Pharmacology & Pharmacy
Nadia Milad, Marie Pineault, Felix Tremblay, Joanie Routhier, Ariane Lechasseur, Marie-Josee Beaulieu, Sophie Aubin, Mathieu C. Morissette
Summary: This study compared the anti-inflammatory effects of IL-1 alpha signaling blockade during active cigarette smoke exposure and during the cessation period using a pre-clinical model. The results showed that blocking IL-1 alpha signaling during smoke exposure delayed the inflammatory response, while the same treatment during cessation accelerated the return to pulmonary inflammatory homeostasis.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Psychology, Clinical
Min-Jeong Yang, Dana Ketcher, Katie Witkiewitz, Marina Unrod, Sana Baban, David W. Wetter, Christine Vinci
Summary: Through qualitative analysis, this study explored participants' lived experiences with mindful smoking during an 8-week group-based smoking cessation and alcohol modification trial. Participants reported that intentionally paying attention to smoking led to heightened awareness of automatic behavior and noticing unpleasant aspects of smoking, potentially facilitating changes in their relationship to smoking.
Article
Multidisciplinary Sciences
Ryan H. Nguyen, Laura B. Vater, Lava R. Timsina, Gregory A. Durm, Katelin Rupp, Keylee Wright, Miranda H. Spitznagle, Brandy Paul, Shadia Jalal, Lisa Carter-Harris, Karen S. Hudmon, Nasser H. Hanna, Patrick J. Loehrer, DuyKhanh P. Ceppa
Summary: The study found that counties with stronger smoke-free air ordinances had lower smoking rates and fewer new lung cancer cases per year. Therefore, strengthening smoke-free air ordinances is crucial for reducing lung cancer incidence.
Article
Microbiology
Danicke Willemse, Chivonne Moodley, Smriti Mehra, Deepak Kaushal
Summary: Smoking is a known added risk factor for tuberculosis, increasing the risk of active TB and reducing cure and treatment completion rates. Cigarette smoke contains harmful compounds that may potentially enhance the virulence of the tubercle bacilli. Further research is needed to explore the impact of cigarette smoke on Mycobacterium tuberculosis and its potential implications for TB treatment efficacy.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Psychology, Clinical
Shirlene D. Wang, Paddy Loftus, Raina D. Pang, Matthew G. Kirkpatrick
Summary: This study examined the impact of baseline and daily self-efficacy on setting daily abstinence plans in pre-quit smokers. The results indicate that self-efficacy plays an important role in helping pre-quit smokers to make and stick to their quitting plans. The study also suggests that smoking behavior and previous abstinence plan setting on the previous day can influence the success of participants' smoking cessation plans.
ADDICTIVE BEHAVIORS
(2021)
Article
Critical Care Medicine
Farzad Moazed, Carolyn Hendrickson, Alejandra Jauregui, Jeffrey Gotts, Amanda Conroy, Kevin Delucchi, Hanjing Zhuo, Mikhaela Arambulo, Kathryn Vessel, Serena Ke, Thomas Deiss, Amy Ni, Aleksandra Leligdowicz, Jason Abbott, Mitchell J. Cohen, Pratik Sinha, Antonio Gomez, Kirsten Kangelaris, Lucy Kornblith, Michael Matthay, Neal Benowitz, Kathleen Liu, Carolyn S. Calfee
Summary: Cigarette smoke exposure is associated with an increased risk of developing ARDS in both pulmonary and nonpulmonary sepsis patients. Among ARDS patients, those with exposure to cigarette smoke have lower systemic inflammation levels, and active smokers also have lower severity of illness compared to non-smokers, indicating that smoking contributes to biological heterogeneity in ARDS.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Medicine, Research & Experimental
Tingting Wu, Keye Xu, Chaobo Liu, Yan Li, Mingcai Li
Summary: This study aimed to investigate the effect of interleukin-37 (IL-37) on cigarette smoke-induced lung inflammation. By administering IL-37-expressing lentivirus to mice, it was found that IL-37 can alleviate weight loss and pulmonary inflammation induced by cigarette smoke. IL-37 also significantly inhibited inflammatory cell recruitment, reduced inflammatory cell increase, and suppressed the production of pro-inflammatory cytokines.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Medicine, Research & Experimental
Jun Liu, Szu-Jung Chen, Ssu-Wei Hsu, Jun Zhang, Ji-Min Li, David C. Yang, Shenwen Gu, Kent E. Pinkerton, Ching-Hsien Chen
Summary: The study found that MARCKS was activated in response to cigarette smoke in human lung cancer cells, specimens, and non-human primate airway epithelium. By investigating its interaction with NF-kappa B-activating protein (NKAP), it revealed MARCKS as a novel NF-kappa B activator in smoke-mediated lung cancer progression.
Article
Psychology, Clinical
Anna E. Epperson, Jan L. Wallander, Anna Song, Sarah Depaoli, Melissa F. Peskin, Marc N. Elliott, Mark A. Schuster
Summary: The study found that intentions and willingness predicted smoking initiation for Black and male adolescents, but not for Latino, White, and female adolescents.
JOURNAL OF HEALTH PSYCHOLOGY
(2021)
Article
Medicine, General & Internal
Neus Altet, Irene Latorre, Maria Angeles Jimenez-Fuentes, Antoni Soriano-Arandes, Raquel Villar-Hernandez, Celia Mila, Pablo Rodriguez-Fernandez, Beatriz Muriel-Moreno, Patricia Comella-del-Barrio, Pere Godoy, Joan-Pau Millet, Maria Luiza de Souza-Galvao, Carlos A. Jimenez-Ruiz, Jose Dominguez
Summary: This study found that exposure to second-hand smoke (SHS) is associated with an increased risk of tuberculosis (TB) and latent TB infection (LTBI) in children. Furthermore, smoking also affects the accuracy of Interferon-Gamma Release Assays (IGRAs) and cytokine immune responses.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, Research & Experimental
Yi Lu, Yuanpu Peter Di, Ming Chang, Xin Huang, Qiuyan Chen, Ni Hong, Beth A. Kahkonen, Marissa E. Di, Chunyan Yu, Evan T. Keller, Jian Zhang
Summary: The study found that cigarette smoke exposure significantly disrupts the balance between bone resorption and bone formation. Short-term smoke exposure effectively induces osteoclast activity and inhibits osteoblast differentiation.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Immunology
Tiantian Cen, Yifeng Mai, Jie Jin, Minxuan Huang, Mingcai Li, Shanshan Wang, Hongying Ma
Summary: Our study aimed to investigate the ability of IL-41 to protect against CS-induced lung inflammation in vivo. The results showed that IL-41 pre-treatment alleviated pulmonary inflammatory infiltration and lung tissue lesions, limited CS-induced weight loss, and promoted the polarization of M2 macrophages. IL-41 also increased the levels of IL-10 and reduced the production of TNF-α, IL-6, and IL-1β.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Review
Chemistry, Medicinal
Sahar Fanoudi, Mohaddeseh Sadat Alavi, Soghra Mehri, Hossein Hosseinzadeh
Summary: Cigarette smoking is a significant risk factor for developing various diseases and cancers, and curcumin has the potential to attenuate the toxic effects of smoking and provide protection.
PHYTOTHERAPY RESEARCH
(2023)
Article
Environmental Sciences
Ki Joon Heo, Gyu Dong Lee, Song Jun Doh, Jae Hee Jung
Summary: This study examined the impact of cigarette smoke on the filtration performance of common face mask materials, revealing a significant reduction in filtration efficiency. The findings suggest that the lifespan of air filters commonly used may be much shorter than expected, leading to potential direct exposure to airborne pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Medicine, Research & Experimental
Camila Liyoko Suehiro, Natalia Tiemi Simokomaki Souza, Emerson Batista da Silva, Maysa Mariana Cruz, Roseane Martins Laia, Stheffany de Oliveira Santos, Fernanda Paula Roncon Santana-Novelli, Thamyres Barros Pereira de Castro, Fernanda D. T. Q. S. Lopes, Nathalia Montouro Pinheiro, Iolanda de Fatima Lopes Calvo Tiberio, Clarice Rosa Olivo, Maria Isabel Alonso-Vale, Marco Antonio Maximo Prado, Vania Ferreira Prado, Alessandra Choqueta de Toledo-Arruda, Carla Maximo Prado
Summary: The effects of aerobic exercise training on pulmonary emphysema in mice are dependent on the integrity of the lung cholinergic signaling.