标题
ALS biomarkers for therapy development: State of the field and future directions
作者
关键词
-
出版物
MUSCLE & NERVE
Volume 53, Issue 2, Pages 169-182
出版商
Wiley
发表日期
2015-11-18
DOI
10.1002/mus.24979
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing
- (2015) Martin H. Schludi et al. ACTA NEUROPATHOLOGICA
- Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity
- (2015) Zhouteng Tao et al. HUMAN MOLECULAR GENETICS
- Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
- (2015) Ana Jovičić et al. NATURE NEUROSCIENCE
- Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis
- (2015) C.-H. Lu et al. NEUROLOGY
- Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: Assessed with [11C]-PBR28
- (2015) Nicole R. Zürcher et al. NeuroImage-Clinical
- Microstructural Changes across Different Clinical Milestones of Disease in Amyotrophic Lateral Sclerosis
- (2015) Francesca Trojsi et al. PLoS One
- Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress
- (2014) Yong-Jie Zhang et al. ACTA NEUROPATHOLOGICA
- Widespread grey matter pathology dominates the longitudinal cerebral MRI and clinical landscape of amyotrophic lateral sclerosis
- (2014) Ricarda A. L. Menke et al. BRAIN
- Mammographic density—a review on the current understanding of its association with breast cancer
- (2014) C. W. Huo et al. BREAST CANCER RESEARCH AND TREATMENT
- Cerebrospinal fluid neurofilament light chain levels: marker of progression to generalized amyotrophic lateral sclerosis
- (2014) R. Tortelli et al. EUROPEAN JOURNAL OF NEUROLOGY
- Influence of serum uric acid levels on prognosis and survival in amyotrophic lateral sclerosis: a meta-analysis
- (2014) Alon Abraham et al. JOURNAL OF NEUROLOGY
- Cortical thickness in ALS: towards a marker for upper motor neuron involvement
- (2014) R. Walhout et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study
- (2014) Ching-Hua Lu et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Serum uric acid level is associated with the prevalence but not with survival of amyotrophic lateral sclerosis in a Chinese population
- (2014) Zhenzhen Zheng et al. METABOLIC BRAIN DISEASE
- Ensuring continued progress in biomarkers for amyotrophic lateral sclerosis
- (2014) Martin R. Turner et al. MUSCLE & NERVE
- Functional pattern of brain FDG-PET in amyotrophic lateral sclerosis
- (2014) M. Pagani et al. NEUROLOGY
- The PRO-ACT database: Design, initial analyses, and predictive features
- (2014) N. Atassi et al. NEUROLOGY
- Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS
- (2014) Zhaoming Su et al. NEURON
- The Extracellular Domain of Neurotrophin Receptor p75 as a Candidate Biomarker for Amyotrophic Lateral Sclerosis
- (2014) Stephanie R. Shepheard et al. PLoS One
- Distinct patterns of cortical atrophy in ALS patients with or without dementia: An MRI VBM study
- (2014) Venkateswaran Rajagopalan et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Amyotrophic Lateral Sclerosis Outcome Measures and the Role of Albumin and Creatinine
- (2014) Adriano Chiò et al. JAMA Neurology
- Value of18Fluorodeoxyglucose–Positron-Emission Tomography in Amyotrophic Lateral Sclerosis
- (2014) Koen Van Laere et al. JAMA Neurology
- Inosine to Increase Serum and Cerebrospinal Fluid Urate in Parkinson Disease
- (2014) Michael A. Schwarzschild et al. JAMA Neurology
- Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72
- (2014) Yvonne S Davidson et al. Acta Neuropathologica Communications
- Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations
- (2013) Ian R. Mackenzie et al. ACTA NEUROPATHOLOGICA
- Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS
- (2013) Tania F. Gendron et al. ACTA NEUROPATHOLOGICA
- Diffusion tensor MRI of the corpus callosum in amyotrophic lateral sclerosis
- (2013) Molly C. Chapman et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- Electrical impedance myography correlates with standard measures of Als severity
- (2013) Seward B. Rutkove et al. MUSCLE & NERVE
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
- (2013) Peter E.A. Ash et al. NEURON
- Molecular Imaging of Microglial Activation in Amyotrophic Lateral Sclerosis
- (2013) Philippe Corcia et al. PLoS One
- Electrophysiologic Biomarkers for Assessing Disease Progression and the Effect of Riluzole in SOD1 G93A ALS Mice
- (2013) Jia Li et al. PLoS One
- Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases
- (2013) Johanna Gaiottino et al. PLoS One
- Cortical Thinning and Clinical Heterogeneity in Amyotrophic Lateral Sclerosis
- (2013) Domenico Maria Mezzapesa et al. PLoS One
- RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
- (2013) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
- (2013) C. Lagier-Tourenne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
- (2013) K. Mori et al. SCIENCE
- Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
- (2013) D. Sareen et al. Science Translational Medicine
- Electrical impedance myography as a biomarker to assess ALS progression
- (2012) Seward B. Rutkove et al. Amyotrophic Lateral Sclerosis
- Neuroanatomical patterns of cerebral white matter involvement in different motor neuron diseases as studied by diffusion tensor imaging analysis
- (2012) Hans-Peter Müller et al. Amyotrophic Lateral Sclerosis
- Fractional Anisotropy in the Posterior Limb of the Internal Capsule and Prognosis in Amyotrophic Lateral Sclerosis
- (2012) Ricarda A. L. Menke et al. ARCHIVES OF NEUROLOGY
- Longitudinal diffusion tensor imaging in amyotrophic lateral sclerosis
- (2012) Carsten Keil et al. BMC NEUROSCIENCE
- Commercial Immunoassays in Biomarkers Studies: Researchers Beware!
- (2012) N. Rifai et al. CLINICAL CHEMISTRY
- Elevated cerebrospinal fluid neurofilament light levels in patients with amyotrophic lateral sclerosis: a possible marker of disease severity and progression
- (2012) R. Tortelli et al. EUROPEAN JOURNAL OF NEUROLOGY
- Relationships between Disease Progression and Serum Levels of Lipid, Urate, Creatinine and Ferritin in Japanese Patients with Amyotrophic Lateral Sclerosis: A Cross-Sectional Study
- (2012) Ken Ikeda et al. INTERNAL MEDICINE
- Phosphorylated neurofilament heavy subunit (pNF-H) in peripheral blood and CSF as a potential prognostic biomarker in amyotrophic lateral sclerosis
- (2012) K. B. Boylan et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Grey matter correlates of clinical variables in amyotrophic lateral sclerosis (ALS): a neuroimaging study of ALS motor phenotype heterogeneity and cortical focality
- (2012) P. Bede et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Transcranial magnetic stimulation and amyotrophic lateral sclerosis: pathophysiological insights
- (2012) Steve Vucic et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging
- (2012) S. Lavisse et al. JOURNAL OF NEUROSCIENCE
- Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
- (2012) Elisa Majounie et al. LANCET NEUROLOGY
- Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration
- (2012) X. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- pNfH is a promising biomarker for ALS
- (2012) Jeban Ganesalingam et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- SOD1 in Cerebral Spinal Fluid as a Pharmacodynamic Marker for Antisense Oligonucleotide Therapy
- (2012) Leah Winer et al. JAMA Neurology
- Neurophysiological index as a biomarker for ALS progression: Validity of mixed effects models
- (2011) Benjamin C. Cheah et al. Amyotrophic Lateral Sclerosis
- Motor Unit Number Index (MUNIX): A novel neurophysiological marker for neuromuscular disorders; test–retest reliability in healthy volunteers
- (2011) Christoph Neuwirth et al. CLINICAL NEUROPHYSIOLOGY
- Electrical impedance myography for monitoring motor neuron loss in the SOD1 G93A amyotrophic lateral sclerosis rat
- (2011) Lucy Lu Wang et al. CLINICAL NEUROPHYSIOLOGY
- Combination of neurofilament heavy chain and complement C3 as CSF biomarkers for ALS
- (2011) Jeban Ganesalingam et al. JOURNAL OF NEUROCHEMISTRY
- Misfolded superoxide dismutase-1 in CSF from amyotrophic lateral sclerosis patients
- (2011) Per Zetterström et al. JOURNAL OF NEUROCHEMISTRY
- Towards a neuroimaging biomarker for amyotrophic lateral sclerosis
- (2011) Martin R Turner et al. LANCET NEUROLOGY
- Multipoint incremental motor unit number estimation as an outcome measure in ALS
- (2011) J. M. Shefner et al. NEUROLOGY
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- The Alzheimer's Disease Neuroimaging Initiative: Progress report and future plans
- (2010) Michael W. Weiner et al. Alzheimers & Dementia
- A pilot trial of memantine and riluzole in ALS: Correlation to CSF biomarkers
- (2010) Todd D. Levine et al. Amyotrophic Lateral Sclerosis
- Grey matter volume changes over the whole brain in amyotrophic lateral sclerosis: A voxel-wise meta-analysis of voxel based morphometry studies
- (2010) Zhiye Chen et al. Amyotrophic Lateral Sclerosis
- An exploratory study of serum urate levels in patients with amyotrophic lateral sclerosis
- (2010) Stefano Zoccolella et al. JOURNAL OF NEUROLOGY
- The relationship between uric acid levels and Huntington's disease progression
- (2010) Peggy Auinger et al. MOVEMENT DISORDERS
- Motor unit number index (MUNIX): A novel neurophysiological technique to follow disease progression in amyotrophic lateral sclerosis
- (2010) Christoph Neuwirth et al. MUSCLE & NERVE
- Compound muscle action potential and motor function in children with spinal muscular atrophy
- (2010) Aga Lewelt et al. MUSCLE & NERVE
- Urate as a Predictor of the Rate of Clinical Decline in Parkinson Disease
- (2009) Alberto Ascherio ARCHIVES OF NEUROLOGY
- Oxidative stress in ALS: Key role in motor neuron injury and therapeutic target
- (2009) Siân C. Barber et al. FREE RADICAL BIOLOGY AND MEDICINE
- Immunoreactivity of the phosphorylated axonal neurofilament H subunit (pNF-H) in blood of ALS model rodents and ALS patients: evaluation of blood pNF-H as a potential ALS biomarker
- (2009) Kevin Boylan et al. JOURNAL OF NEUROCHEMISTRY
- CSF neurofilament protein analysis in the differential diagnosis of ALS
- (2009) Thierry S. Reijn et al. JOURNAL OF NEUROLOGY
- Early Excitability Changes in Lumbar Motoneurons of Transgenic SOD1G85R and SOD1G93A-Low Mice
- (2009) Arnaud Pambo-Pambo et al. JOURNAL OF NEUROPHYSIOLOGY
- Voxel-Based Morphometry: An Automated Technique for Assessing Structural Changes in the Brain
- (2009) J. L. Whitwell JOURNAL OF NEUROSCIENCE
- Low uric acid levels in serum of patients with ALS: Further evidence for oxidative stress?
- (2009) D. Keizman et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Electrical impedance myography: Background, current state, and future directions
- (2009) Seward B. Rutkove MUSCLE & NERVE
- Comparison of [11C]-(R)-PK 11195 and [11C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker
- (2009) William C. Kreisl et al. NEUROIMAGE
- Transcranial magnetic stimulation in ALS: Utility of central motor conduction tests
- (2009) A. G. Floyd et al. NEUROLOGY
- Longitudinal assessment of grey matter contraction in amyotrophic lateral sclerosis: A tensor based morphometry study
- (2008) Federica Agosta et al. Amyotrophic Lateral Sclerosis
- Biomarkers in amyotrophic lateral sclerosis
- (2008) Martin R Turner et al. LANCET NEUROLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started