A STING-dependent innate-sensing pathway mediates resistance to corneal HSV-1 infection via upregulation of the antiviral effector tetherin

Monocytes and infection: Modulator, messenger and effector

(2015) Huizhong Xiong et al.   IMMUNOBIOLOGY

Degeneration and Regeneration of Corneal Nerves in Response to HSV-1 Infection

(2015) A. J. Chucair-Elliott et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Bst2/Tetherin Is Induced in Neurons by Type I Interferon and Viral Infection but Is Dispensable for Protection against Neurotropic Viral Challenge

(2015) Alicia M. Holmgren et al.   JOURNAL OF VIROLOGY

Suppression of systemic autoimmunity by the innate immune adaptor STING

(2015) Shruti Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids

(2014) Jiaxi Wu et al.   Annual Review of Immunology

Monocyte homeostasis and the plasticity of inflammatory monocytes

(2014) Andrew J. Mitchell et al.   CELLULAR IMMUNOLOGY

Tetherin Promotes the Innate and Adaptive Cell-Mediated Immune Response against Retrovirus Infection In Vivo

(2014) S. X. Li et al.   JOURNAL OF IMMUNOLOGY

VEGF-B selectively regenerates injured peripheral neurons and restores sensory and trophic functions

(2014) Victor H. Guaiquil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Counteraction of the multifunctional restriction factor tetherin

(2014) Daniel Sauter   Frontiers in Microbiology

HSV-1 Targets Lymphatic Vessels in the Eye and Draining Lymph Node of Mice Leading to Edema in the Absence of a Functional Type I Interferon Response

(2013) Katie M. Bryant-Hudson et al.   AMERICAN JOURNAL OF PATHOLOGY

Microglia and a Functional Type I IFN Pathway Are Required To Counter HSV-1-Driven Brain Lateral Ventricle Enlargement and Encephalitis

(2013) C. D. Conrady et al.   JOURNAL OF IMMUNOLOGY

Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors

(2013) K. A. Horan et al.   JOURNAL OF IMMUNOLOGY

Emerging Role of the Host Restriction Factor Tetherin in Viral Immune Sensing

(2013) Dominik Hotter et al.   JOURNAL OF MOLECULAR BIOLOGY

Tetherin Restricts Herpes Simplex Virus 1 and Is Antagonized by Glycoprotein M

(2013) C. Blondeau et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 1 Counteracts Tetherin Restriction via Its Virion Host Shutoff Activity

(2013) H. L. Zenner et al.   JOURNAL OF VIROLOGY

Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche

(2012) Jaclyn Sceneay et al.   CANCER RESEARCH

Innate Sensing of HIV-1 Assembly by Tetherin Induces NFκB-Dependent Proinflammatory Responses

(2012) Rui Pedro Galão et al.   Cell Host & Microbe

IFN-α-driven CCL2 production recruits inflammatory monocytes to infection site in mice

(2012) C D Conrady et al.   Mucosal Immunology

Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16

(2012) C D Conrady et al.   Mucosal Immunology

STING and the innate immune response to nucleic acids in the cytosol

(2012) Dara L Burdette et al.   NATURE IMMUNOLOGY

Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein

(2012) M. H. Orzalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

(2012) Y. Tanaka et al.   Science Signaling

Mast cell modulation of the vascular and lymphatic endothelium

(2011) C. A. Kunder et al.   BLOOD

Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

(2011) Glen N Barber   CURRENT OPINION IN IMMUNOLOGY

A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment

(2011) Shawn Rose et al.   CYTOMETRY PART A

Interferon-Induced Tetherin Restricts Vesicular Stomatitis Virus Release in Neurons

(2011) Sreeja Sarojini et al.   DNA AND CELL BIOLOGY

Chromatin Dynamics of Gene Activation and Repression in Response to Interferon α (IFNα) Reveal New Roles for Phosphorylated and Unphosphorylated Forms of the Transcription Factor STAT2

(2011) Barbara Testoni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Autophagy by α-Herpesviruses in Myeloid Cells Is Mediated by Cytoplasmic Viral DNA through a Mechanism Dependent on Stimulator of IFN Genes

(2011) Simon B. Rasmussen et al.   JOURNAL OF IMMUNOLOGY

Herpes Simplex Virus Glycoproteins gB and gD Function in a Redundant Fashion To Promote Secondary Envelopment

(2011) D. C. Johnson et al.   JOURNAL OF VIROLOGY

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

(2011) Zhiqiang Zhang et al.   NATURE IMMUNOLOGY

Host factors involved in retroviral budding and release

(2011) Juan Martin-Serrano et al.   NATURE REVIEWS MICROBIOLOGY

In vivo expression profile of the antiviral restriction factor and tumor-targeting antigen CD317/BST-2/HM1.24/tetherin in humans

(2011) E. Erikson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune sensing of DNA viruses

(2011) Vijay A.K. Rathinam et al.   VIROLOGY

Type I Interferon Signaling Regulates Ly6Chi Monocytes and Neutrophils during Acute Viral Pneumonia in Mice

(2011) Sang-Uk Seo et al.   PLoS Pathogens

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

Histamine deficiency promotes inflammation-associated carcinogenesis through reduced myeloid maturation and accumulation of CD11b+Ly6G+ immature myeloid cells

(2010) Xiang Dong Yang et al.   NATURE MEDICINE

Cellular Localization of the Herpes Simplex Virus ICP0 Protein Dictates Its Ability to Block IRF3-Mediated Innate Immune Responses

(2010) Patrick Paladino et al.   PLoS One

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

(2010) M. Kowanetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A CD317/tetherin–RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells

(2009) Ruth Rollason et al.   JOURNAL OF CELL BIOLOGY

VEGF-A expression by HSV-1–infected cells drives corneal lymphangiogenesis

(2009) Todd R. Wuest et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY