Article
Nutrition & Dietetics
Feng-Min Zhang, Xiao-Lei Chen, Qian Wu, Wen-Xi Dong, Qian-Tong Dong, Xian Shen, Han-Ping Shi, Zhen Yu, Cheng-Le Zhuang
Summary: This study developed and validated nomograms for predicting low muscle mass and muscle radiodensity based on preoperative data in gastric cancer patients. The nomograms showed good discrimination and calibration in diagnosing sarcopenia and malnutrition, with high agreement ratios between the nomograms and actual observations. These diagnostic tools can facilitate early identification and interventions for at-risk populations.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Wei Ji, XiangLiang Liu, Pengfei Liu, YuWei He, YiXin Zhao, Kaiwen Zheng, JiuWei Cui, Wei Li
Summary: Research shows that reduced muscle mass is an indicator of malnutrition. By using the appendicular skeletal muscle mass index (ASMI) and fat-free mass index (FFMI), the presence of reduced muscle mass can be determined. These indicators have a significant impact in diagnosing severe malnutrition and predicting survival rates in cancer patients.
FRONTIERS IN NUTRITION
(2023)
Article
Pediatrics
Sukru Gungor, Adil Dogan
Summary: Muscle atrophy is a marker for nutritional deficiency, and the diaphragm, as both a skeletal and respiratory muscle, may be affected by malnutrition. This study aimed to compare diaphragm thickness in pediatric patients with primary malnutrition and a healthy control group. The results showed that the malnourished group had thinner diaphragms, particularly among those with moderate and severe malnutrition. There was a weak positive correlation between weight/height Z score and diaphragm thickness.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Review
Geriatrics & Gerontology
Patrick Casey, Mohamed Alasmar, John McLaughlin, Yeng Ang, Jamie McPhee, Priam Heire, Javed Sultan
Summary: Ultrasound is a promising tool for measuring skeletal muscle mass and quality, and can predict functional capacity, clinical outcomes, and survival. However, further standardization is needed before ultrasound can be widely used in nutritionally vulnerable patients.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Nutrition & Dietetics
Bulent Saka, Murat Bektas, Oguz Kagan Bakkaloglu, Shirkhan Amikishiyev, Goktug Saribeyliler, Tarik Onur Tiryaki, Burak Ince, Ramazan Cakmak, Serpil Buyukdemir, Bahar Ozmen Senturk, Sebile Nilgun Erten, Mustafa Altinkaynak, Timur Selcuk Akpinar
Summary: Clinical nutrition outpatient clinics (CNOCs) play a crucial role in the diagnosis, treatment, and follow-up of patients with malnutrition (MN) and sarcopenia. They can effectively restore muscle mass, especially in patients aged 65 years and above and those with chronic diseases.
Article
Geriatrics & Gerontology
Yoshiharu Kinugasa, Takeshi Sota, Kensuke Nakamura, Masayuki Hirai, Masahiko Kato, Kazuhiro Yamamoto
Summary: This study found an association between muscle weakness and carnitine insufficiency in patients with heart failure. Specifically, the association was closer with sarcopenia, a form of muscle weakness. The results suggest that carnitine insufficiency may be a potential therapeutic target for sarcopenia in these patients.
GERIATRICS & GERONTOLOGY INTERNATIONAL
(2023)
Review
Nutrition & Dietetics
Giorgina Barbara Piccoli, Tommy Cederholm, Carla Maria Avesani, Stephan J. L. Bakker, Vincenzo Bellizzi, Cristina Cuerda, Adamasco Cupisti, Alice Sabatino, Stephane Schneider, Massimo Torreggiani, Denis Fouque, Juan Jesus Carrero, Rocco Barazzoni
Summary: Increased life expectancy presents significant challenges to healthcare systems globally, including the rise in chronic kidney disease (CKD) and malnutrition-protein-energy wasting (PEW) in older adults, leading to poor clinical outcomes. A critical review paper by ESPEN and ERN-ERA aims to summarize key concepts in preventing and treating CKD progression and impaired nutritional status, and provide guidance on defining optimal protein and energy intake in varying CKD severity. Careful assessment and individualized approach are necessary, considering malnutrition-PEW status, kidney function, and patient preferences. Greater awareness and research are needed to improve nutritional care for this growing patient subgroup.
CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Dong-Dong Huang, Gao-Feng Wu, Xin Luo, Hao-Nan Song, Wen-Bin Wang, Na-Xin Liu, Zhen Yu, Qian-Tong Dong, Xiao-Lei Chen, Jing-Yi Yan
Summary: The study found that for overweight patients undergoing radical gastrectomy for gastric cancer, GLIM-defined malnutrition alone has limited predictive value for postoperative complications and/or survival. However, adding low gait speed or muscle quality to GLIM-defined malnutrition significantly improved the predictive power and remained significant in multivariate analysis. Incorporating gait speed, especially, into nutritional assessment protocols could enhance predictive value for postoperative outcomes in these patients.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Junjie Wang, Qiulin Zhuang, Shanjun Tan, Jiahao Xu, Yanni Zhang, Mingyue Yan, Shuhao Li, Zhige Zhang, Guohao Wu
Summary: This study aimed to investigate the nutritional and functional status of geriatric patients and their association with postoperative complications. The results showed that geriatric patients are at a greater risk for malnutrition and malnutrition is associated with postoperative complications. Therefore, nutrition evaluation and timely interventions are crucial in the preoperative workup for geriatric patients.
Article
Nutrition & Dietetics
Leonie Mueller, Nicole Mentil, Nathalie Staub, Stephanie Griot, Tobias Olpe, Felice Burn, Sebastian Schindera, Beat Mueller, Philipp Schuetz, Zeno Stanga, Annic Baumgartner
Summary: This study examined the association of skeletal muscle index (SMI) at the thoracic level with nutritional and clinical outcomes and response to nutritional intervention. The results showed that SMI at the thoracic vertebra provided limited prognostic information regarding clinical outcomes and nutritional treatment response.
Article
Gastroenterology & Hepatology
Sara Brown, Brooks Richardson, Erin Bouquet, Elise Reid, Evan Mercer, Michael Goncalves, Ashley Spann, Jeffrey Annis, Evan Brittain, Anthony Dreher, Sophoclis Alexopoulos, James C. Slaughter, Heidi J. Silver, Manhal Izzy
Summary: Sarcopenia does not seem to improve post-liver transplantation. Instead, it may worsen, leading to a nearly doubled prevalence of sarcopenia in patients with long-term follow-up. However, sarcopenia does not influence post-transplant outcomes.
Article
Nutrition & Dietetics
David L. Chan, Stephen J. Clarke, Alexander Engel, Connie I. Diakos, Nick Pavlakis, Paul J. Roach, Dale L. Bailey, Judith Bauer, Merran Findlay
Summary: The study found that sarcopenia and myosteatosis are common in NEN patients but were not associated with worsened survival outcomes in this study.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Gastroenterology & Hepatology
Babu Lal Meena, Sunil Taneja, Puneeta Tandon, Nancy Sahni, Raghuraman Soundararajan, Ujjwal Gorsi, Arka De, Nipun Verma, Madhumita Premkumar, Ajay Duseja, Radha K. Dhiman, Virendra Singh
Summary: This study found that a 6-month dietitian-supported home-based intensive outpatient nutrition therapy significantly improved frailty and sarcopenia in patients with decompensated cirrhosis. Adherent patients also showed improvement in liver disease scores and reduction in mortality.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Nutrition & Dietetics
Laura Salvadori, Manuela Mandrone, Tommaso Manenti, Catia Ercolani, Luca Cornioli, Mariacaterina Lianza, Paola Tomasi, Sara Chiappalupi, Ester Sara Di Filippo, Stefania Fulle, Ferruccio Poli, Guglielmo Sorci, Francesca Riuzzi
Summary: The study identified the WST (Withania somnifera, Silybum marianum, Trigonella foenum-graecum) formulation as effective in protecting C2C12 myotubes against MyHC-II degradation, by stimulating protein synthesis and myoblast differentiation. WST has the potential to sustain nutrition in atrophic myotubes and rescue size and functionality in both young and sarcopenic myotubes.
Article
Nutrition & Dietetics
Li-Ping Zhou, Ding-Ye Yu, Bing-Wei Ma, Zi-Le Shen, Hong-Bo Zou, Xian-Zhong Zhang, Xia-Lin Yan, Cheng-Le Zhuang, Zhen Yu
Summary: This study demonstrated that handgrip strength can be used as a substitute for muscle mass in the diagnostic criteria of the Global Leadership Initiative on Malnutrition (GLIM) for patients with gastrointestinal cancer, showing consistency and diagnostic value.