Article
Multidisciplinary Sciences
Rachel D. Stelmach, Miriam Rabkin, Kouame Abo, Irma Ahoba, Mahena Gildas Anago, Rodrigo Boccanera, Hermann Brou, Rebecca Flueckiger, Kieran Hartsough, Martin Msukwa, Jennifer Zech, Felicity Young, Rachel Nugent
Summary: Despite the availability of free ART in Cote d'Ivoire, most participants still reported out-of-pocket spending on health care, with those with co-morbid NCDs experiencing higher costs.
Article
Clinical Neurology
Sabine El-Halabi, Daniel H. Cooper, Danielle S. Cha, Joshua Daniel Rosenblat, Barjot Gill, Nelson B. Rodrigues, Orly Lipsitz, Roger S. McIntyre, Hartej Gill
Summary: This review examined the effects of antidepressant medications on antiretroviral therapy (ART) adherence in HIV-positive individuals with diagnosed Major Depressive Disorder (MDD). The findings suggest that antidepressant treatment may improve adherence to HIV treatments and reduce missed HIV medication dosage. However, further studies are needed to explore the effects of different psychotropic agents on adherence behaviors among patients with HIV.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Multidisciplinary Sciences
Njambi Njuguna, Nelly Mugo, Omu Anzala, Marianne Mureithi, Elizabeth Irungu, Joyce Wamicwe, Jared M. Baeten, Renee Heffron
Summary: A risk scoring tool was developed using data from KenyaEMR to identify individuals likely to have unsuppressed viral load 18 months post-ART initiation. The tool could improve efficiency in differentiated care models.
Article
Public, Environmental & Occupational Health
Gabrielle Bruser, Ritah Katasi, Lily Ziyue Zhang, Miriam Namasinga, Eric Arts, Cissy Kityo, Isaac Luginaah
Summary: This study investigated challenges to cART treatment adherence and outcomes for HIV-1 patients in Kampala, Uganda. Surprisingly, patients living more than 2 hours away from the treatment facility were less likely to miss their daily doses, while those with high-income employment and in partnered relationships were more likely to miss doses. These findings suggest that stigma and social factors may play a significant role in treatment adherence among HIV-positive individuals in Kampala.
Article
Public, Environmental & Occupational Health
Clara Tam, Tim Wesseling, Lu Wang, Kate Salters, David M. Moore, Nicole Dawydiuk, Julia Zhu, Sean Grieve, Brittany Bingham, Taylor Mclinden, Robert Hogg, Rolando Barrios
Summary: Social support is beneficial for individuals managing chronic illnesses, and it may help improve treatment outcomes for people living with HIV, especially for those who face disparities in treatment. Factors such as history of injection drug use, Indigenous identity, recent sexual activity, marital status, lifetime violence experiences, and mental health disorders are related to levels of social support. Higher levels of social support are associated with reduced likelihood of HIV treatment interruptions.
Article
Public, Environmental & Occupational Health
Alexandra L. Rose, Jennifer M. Belus, Tianzhou Ma, Jasper S. Lee, Christine Wan, Andres De los Reyes, John A. Joska, Lena S. Andersen, Bronwyn Myers, Jessica F. Magidson
Summary: Harmful alcohol consumption negatively affects adherence to antiretroviral therapy (ART) among HIV patients. This study found that ART adherence was worse on weekends/holidays, and next-day adherence was significantly worse among men and in the context of weekend alcohol use. These findings emphasize the importance of tailoring intervention strategies to support ART adherence during weekend drinking and for men engaged in heavy episodic drinking.
Article
Nursing
Lilian Yiryuo, Wahab Osman, Stephen Kpekura
Summary: This study aimed to explore the beliefs of family caregivers on adherence to Anti-Retroviral Therapy (ART) among children living with HIV/AIDS. The results showed that most caregivers believed in the effectiveness of ART in improving their children's health, but some also believed in praying and using herbal/local treatments to augment ART.
Article
Public, Environmental & Occupational Health
Joana Falcao, Allison Zerbe, Claude Ann Mellins, Joanne Mantell, Kirsty Brittain, Bill Kapogiannis, Eduarda Pimentel de Gusmao, Teresa Beatriz Simione, Elaine J. Abrams
Summary: In Mozambique, HIV infection remains a leading cause of adolescent mortality, with the population of adolescents living with vertically-acquired HIV growing. The study found that HIV-related secrecy prevails among ALHIV, requiring support from caregivers and healthcare providers. Adolescent-friendly services, including peer support, sexual and reproductive health services, and preparation for independent health management, are crucial for promoting ALHIV health.
Article
Public, Environmental & Occupational Health
Emily C. Williams, Kathleen A. McGinnis, Anna D. Rubinsky, Theresa E. Matson, Jennifer F. Bobb, Gwen T. Lapham, E. Jennifer Edelman, Derek D. Satre, Sheryl L. Catz, Julie E. Richards, Kendall J. Bryant, Brandon D. L. Marshall, Kevin L. Kraemer, Stephen Crystal, Adam J. Gordon, Melissa Skanderson, David A. Fiellin, Amy C. Justice, Katharine A. Bradley
Summary: Alcohol use has been found to increase non-adherence to antiretroviral therapy among persons living with HIV, with dynamic changes in alcohol use significantly impacting medication adherence. Both increases and decreases in AUDIT-C scores were associated with greater decreases in adherence. Those with dynamic alcohol use, potentially indicating alcohol use disorder, should be considered for adherence interventions.
Article
Multidisciplinary Sciences
Bilema Mwambenu, Vundli Ramoloko, Ria Laubscher, Ute Feucht
Summary: This study investigated growth patterns and factors associated with suboptimal growth in adolescents with perinatally-acquired HIV infection. The results showed that suboptimal growth is a significant health concern in adolescents with perinatally-acquired HIV infection, especially in boys who started ART later and had baseline stunting.
Review
Multidisciplinary Sciences
Nande Putta, Caitlin E. Hansen, Melissa C. Funaro, Melissa Campbell, Shaffiq Essajee, Dorothy Mbori-Ngacha, Shadrack Frimpong, Shi-Yi Wang, Elijah Paintsil
Summary: This systematic review aims to evaluate the most effective interventions, models, programs, and strategies to optimize the delivery of services for testing, linkage, treatment, and retention of children and adolescents living with HIV globally. The review will provide synthesized evidence to guide national governments and healthcare providers in prioritizing and adopting evidence-based service delivery approaches for this population.
Article
Multidisciplinary Sciences
Tugume Peterson Gordon, Muhwezi Talbert, Maud Kamatenesi Mugisha, Ainamani Elvis Herbert
Summary: This study aimed to investigate HIV viral suppression levels among adolescents in Kabale district and the associated clinical, adherence, and psychosocial factors. The findings showed that factors such as good nutrition status, absence of severe opportunistic infections, no treatment interruptions, participation in support groups, and support from family members were significantly associated with viral load suppression.
Article
Multidisciplinary Sciences
Mhairi Maskew, Kieran Sharpey-Schafer, Lucien De Voux, Thomas Crompton, Jacob Bor, Marcus Rennick, Admire Chirowodza, Jacqui Miot, Seithati Molefi, Chuka Onaga, Pappie Majuba, Ian Sanne, Pedro Pisa
Summary: This study applied predictive machine learning algorithms to HIV programmatic data from South Africa and developed models to predict patient attendance and viral load suppression. Important predictors included previous visit history, viral load testing frequency, visit time, age, and treatment duration. The results showed that machine learning can effectively identify HIV patients at risk of disengagement and unsuppressed viral load.
SCIENTIFIC REPORTS
(2022)
Review
Environmental Sciences
Kingsley Stephen Orievulu, Sonja Ayeb-Karlsson, Sthembile Ngema, Kathy Baisley, Frank Tanser, Nothando Ngwenya, Janet Seeley, Willem Hanekom, Kobus Herbst, Dominic Kniveton, Collins C. Iwuji
Summary: This article systematically reviews the impact of climate change on antiretroviral therapy (ART) adherence in HIV-positive individuals in Africa. The narrative synthesis of 111 studies reveals that factors such as economic and livelihood conditions, comorbidities and ART regimens, human mobility, and psychobehavioural dispositions and support systems interact in complex ways in the drought-ART adherence nexus. It emphasizes the need for more integrated research approaches and interventions.
LANCET PLANETARY HEALTH
(2022)
Article
Psychiatry
Daniel Hernandez-Huerta, Carlos Parro-Torres, Agustin Madoz-Gurpide, Maria Jesus Perez-Elias, Santiago Moreno-Guillen, Enriqueta Ochoa-Mangado
Summary: This study identified that Neuroticism and Impulsivity were associated with poor ART adherence, while Order and Values were associated with good ART adherence among PLWHA. It suggests that personality traits play a role in ART adherence, and considering these traits during assessment may help identify individuals at risk of poor adherence.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2021)
