Neferine Attenuates the Protein Level and Toxicity of Mutant Huntingtin in PC-12 Cells via Induction of Autophagy

Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

(2014) Betty Yuen Kwan Law et al.   Scientific Reports

Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells

(2013) Paramasivan Poornima et al.   FOOD CHEMISTRY

Repeat-associated non-ATG (RAN) translation in neurological disease

(2013) J. D. Cleary et al.   HUMAN MOLECULAR GENETICS

Onjisaponin B Derived from Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant α-Synuclein and Huntingtin in PC-12 Cells

(2013) An-Guo Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells

(2013) V KW Wong et al.   Cell Death & Disease

Traditional Chinese medicine: a promising candidate for the treatment of Alzheimer’s disease

(2013) Zhi-Kun Sun et al.   Translational Neurodegeneration

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Adverse events associated with mTOR inhibitors

(2012) Nicolas Pallet et al.   Expert Opinion On Drug Safety

SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

(2011) Faisal Fecto   ARCHIVES OF NEUROLOGY

Protective effect of neferine on endothelial cell nitric oxide production induced by lysophosphatidylcholine: the role of the DDAH–ADMA pathway

(2011) Zhen-Yu Peng et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Inositol Hexakisphosphate Kinases Induce Cell Death in Huntington Disease

(2011) Eiichiro Nagata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic effect of hyperthermia and neferine on reverse multidrug resistance in adriamycin-resistant SGC7901/ADM gastric cancer cells

(2011) Chenghui Huang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation

(2011) David G. McEwan et al.   TRENDS IN CELL BIOLOGY

Ageing, neurodegeneration and Parkinson's disease

(2010) J. V. Hindle   AGE AND AGEING

Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells

(2010) Y. Suh et al.   CARCINOGENESIS

Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease

(2010) C. Rose et al.   HUMAN MOLECULAR GENETICS

Inositol hexakisphosphate kinases promote autophagy

(2010) Eiichiro Nagata et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical Inducers of Autophagy That Enhance the Clearance of Mutant Proteins in Neurodegenerative Diseases

(2010) Maurizio Renna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

(2010) Ashley R. Winslow et al.   JOURNAL OF CELL BIOLOGY

Anti-amnesic activity of neferine with antioxidant and anti-inflammatory capacities, as well as inhibition of ChEs and BACE1

(2010) Hyun Ah Jung et al.   LIFE SCIENCES

Alisol B, a Novel Inhibitor of the Sarcoplasmic/Endoplasmic Reticulum Ca2+ ATPase Pump, Induces Autophagy, Endoplasmic Reticulum Stress, and Apoptosis

(2010) B. Y. K. Law et al.   MOLECULAR CANCER THERAPEUTICS

Autophagy gone awry in neurodegenerative diseases

(2010) Esther Wong et al.   NATURE NEUROSCIENCE

Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells

(2010) Li Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer

(2008) Henna Heinonen et al.   BMC GENOMICS

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL