Obscurins: Unassuming giants enter the spotlight

The kinase domains of obscurin interact with intercellular adhesion proteins

(2013) Li-Yen R. Hu et al.   FASEB JOURNAL

CPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegans

(2013) Adam Warner et al.   MOLECULAR BIOLOGY OF THE CELL

Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization

(2012) Mohammad M Ghahramani Seno et al.   BMC GENOMICS

The sarcomeric cytoskeleton as a target for pharmacological intervention

(2012) Ay Lin Kho et al.   CURRENT OPINION IN PHARMACOLOGY

Contribution of the OBSCN Nonsynonymous Variants to Aspirin Exacerbated Respiratory Disease Susceptibility in Korean Population

(2012) Jeong-Hyun Kim et al.   DNA AND CELL BIOLOGY

Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance

(2012) Nicole A. Perry et al.   FASEB JOURNAL

The function of the M-line protein obscurin in controlling the symmetry of the sarcomere in the flight muscle of Drosophila

(2012) A. Katzemich et al.   JOURNAL OF CELL SCIENCE

Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover

(2012) Stephan Lange et al.   MOLECULAR BIOLOGY OF THE CELL

UNC-89 (obscurin) binds to MEL-26, a BTB-domain protein, and affects the function of MEI-1 (katanin) in striated muscle of Caenorhabditis elegans

(2012) Kristy J. Wilson et al.   MOLECULAR BIOLOGY OF THE CELL

Hydrophobic residues in small ankyrin 1 participate in binding to obscurin

(2012) Chris D. Willis et al.   MOLECULAR MEMBRANE BIOLOGY

Large Isoforms of UNC-89 (Obscurin) Are Required for Muscle Cell Architecture and Optimal Calcium Release in Caenorhabditis elegans

(2012) Patrick M. Spooner et al.   PLoS One

Obscurin Depletion Impairs Organization of Skeletal Muscle in Developing Zebrafish Embryos

(2011) Maide Ö. Raeker et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Electrostatic Interactions Mediate Binding of Obscurin to Small Ankyrin 1: Biochemical and Molecular Modeling Studies

(2011) Ben Busby et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization and Comparison of Two Binding Sites on Obscurin for Small Ankyrin 1

(2010) Ben Busby et al.   BIOCHEMISTRY

Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex

(2010) S. Pernigo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted deletion of the zebrafish obscurin A RhoGEF domain affects heart, skeletal muscle and brain development

(2009) Maide Ö. Raeker et al.   DEVELOPMENTAL BIOLOGY

TC10 controls human myofibril organization and is activated by the sarcomeric RhoGEF obscurin

(2009) M. Coisy-Quivy et al.   JOURNAL OF CELL SCIENCE

Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum

(2009) S. Lange et al.   JOURNAL OF CELL SCIENCE

A LIM-9 (FHL) / SCPL-1 (SCP) Complex Interacts with the C-terminal Protein Kinase Regions of UNC-89 (Obscurin) in Caenorhabditis elegans Muscle

(2009) Ge Xiong et al.   JOURNAL OF MOLECULAR BIOLOGY

Obscurin Interacts with a Novel Isoform of MyBP-C Slow at the Periphery of the Sarcomeric M-Band and Regulates Thick Filament Assembly

(2009) Maegen A. Ackermann et al.   MOLECULAR BIOLOGY OF THE CELL

The Rho-Guanine Nucleotide Exchange Factor Domain of Obscurin Activates RhoA Signaling in Skeletal Muscle

(2009) Diana L. Ford-Speelman et al.   MOLECULAR BIOLOGY OF THE CELL

Muscle Giants: Molecular Scaffolds in Sarcomerogenesis

(2009) Aikaterini Kontrogianni-Konstantopoulos et al.   PHYSIOLOGICAL REVIEWS

New aspects of obscurin in human striated muscles

(2008) Lena Carlsson et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Early incorporation of obscurin into nascent sarcomeres: implication for myofibril assembly during cardiac myogenesis

(2008) Andrei B. Borisov et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Obscurin Targets Ankyrin-B and Protein Phosphatase 2A to the Cardiac M-line

(2008) Shane R. Cunha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band - implications for hereditary myopathies

(2008) A. Fukuzawa et al.   JOURNAL OF CELL SCIENCE

The DH-PH Region of the Giant Protein UNC-89 Activates RHO-1 GTPase in Caenorhabditis elegans Body Wall Muscle

(2008) Hiroshi Qadota et al.   JOURNAL OF MOLECULAR BIOLOGY

The Rho-Guanine Nucleotide Exchange Factor Domain of Obscurin Regulates Assembly of Titin at the Z-Disk through Interactions with Ran Binding Protein 9

(2008) Amber L. Bowman et al.   MOLECULAR BIOLOGY OF THE CELL

A Novel Protein Phosphatase is a Binding Partner for the Protein Kinase Domains of UNC-89 (Obscurin) in Caenorhabditis elegans

(2008) Hiroshi Qadota et al.   MOLECULAR BIOLOGY OF THE CELL

Developmental expression and differential cellular localization of obscurin and obscurin-associated kinase in cardiac muscle cells

(2007) Andrei B. Borisov et al.   JOURNAL OF CELLULAR BIOCHEMISTRY