Deciphering the role of malin in the lafora progressive myoclonus epilepsy

Malin Regulates Wnt Signaling Pathway through Degradation of Dishevelled2

(2012) Jaiprakash Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Laforin, a dual-specificity phosphatase involved in Lafora disease, is phosphorylated at Ser25by AMP-activated protein kinase

(2011) Carlos Romá-Mateo et al.   BIOCHEMICAL JOURNAL

Lafora disease E3-ubiquitin ligase malin is related to TRIM32 at both the phylogenetic and functional level

(2011) Carlos Romá-Mateo et al.   BMC EVOLUTIONARY BIOLOGY

Phosphate Incorporation during Glycogen Synthesis and Lafora Disease

(2011) Vincent S. Tagliabracci et al.   Cell Metabolism

Neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of Lafora disease

(2011) Jordi Valles-Ortega et al.   EMBO Molecular Medicine

Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy

(2011) Olga Criado et al.   HUMAN MOLECULAR GENETICS

Malin and laforin are essential components of a protein complex that protects cells from thermal stress

(2011) S. Sengupta et al.   JOURNAL OF CELL SCIENCE

Lafora progressive myoclonus epilepsy: NHLRC1 mutations affect glycogen metabolism

(2011) Philippe Couarch et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The Laforin-Malin Complex Negatively Regulates Glycogen Synthesis by Modulating Cellular Glucose Uptake via Glucose Transporters

(2011) P. K. Singh et al.   MOLECULAR AND CELLULAR BIOLOGY

Lafora disease ubiquitin ligase malin promotes proteasomal degradation of neuronatin and regulates glycogen synthesis

(2011) Jaiprakash Sharma et al.   NEUROBIOLOGY OF DISEASE

Impaired autophagy: a link between neurodegenerative diseases and progressive myoclonus epilepsies

(2011) Mira Polajnar et al.   TRENDS IN MOLECULAR MEDICINE

Glycogen hyperphosphorylation underlies lafora body formation

(2010) Julie Turnbull et al.   ANNALS OF NEUROLOGY

Sequestration of chaperones and proteasome into Lafora bodies and proteasomal dysfunction induced by Lafora disease-associated mutations of malin

(2010) Sudheendra N.R. Rao et al.   HUMAN MOLECULAR GENETICS

Laforin, the most common protein mutated in Lafora disease, regulates autophagy

(2010) Carmen Aguado et al.   HUMAN MOLECULAR GENETICS

Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin

(2010) Anna A. DePaoli-Roach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Laforin–Malin Complex, Involved in Lafora Disease, Promotes the Incorporation of K63-linked Ubiquitin Chains into AMP-activated Protein Kinase β Subunits

(2010) Daniel Moreno et al.   MOLECULAR BIOLOGY OF THE CELL

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Conservation of the glucan phosphatase laforin is linked to rates of molecular evolution and the glucan metabolism of the organism

(2009) Matthew S Gentry et al.   BMC EVOLUTIONARY BIOLOGY

Lafora progressive myoclonus epilepsy: A meta-analysis of reported mutations in the first decade following the discovery of theEPM2AandNHLRC1genes

(2009) Shweta Singh et al.   HUMAN MUTATION

Co-chaperone CHIP Stabilizes Aggregate-prone Malin, a Ubiquitin Ligase Mutated in Lafora Disease

(2009) Sudheendra N. R. Rao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated Protein Kinase Phosphorylates R5/PTG, the Glycogen Targeting Subunit of the R5/PTG-Protein Phosphatase 1 Holoenzyme, and Accelerates Its Down-regulation by the Laforin-Malin Complex

(2009) Santiago Vernia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Building ubiquitin chains: E2 enzymes at work

(2009) Yihong Ye et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Increased Endoplasmic Reticulum Stress and Decreased Proteasomal Function in Lafora Disease Models Lacking the Phosphatase Laforin

(2009) Santiago Vernia et al.   PLoS One

Lafora disease: insights into neurodegeneration from plant metabolism

(2009) Matthew S. Gentry et al.   TRENDS IN BIOCHEMICAL SCIENCES

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

The malin–laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin–proteasome system

(2008) Punitee Garyali et al.   HUMAN MOLECULAR GENETICS

Abnormal Metabolism of Glycogen Phosphate as a Cause for Lafora Disease

(2008) Vincent S. Tagliabracci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY