期刊
ACTA BIOCHIMICA POLONICA
卷 62, 期 1, 页码 23-34出版社
ACTA BIOCHIMICA POLONICA
DOI: 10.18388/abp.2014_885
关键词
bioconversion; biodiesel; carbon source; Escherichia coli; glycerol; 1,3-propanediol
资金
- European Union from the European Regional Development Fund [PO IG 01.01.02-00-074/09]
- European Union under the European Social Fund
In the face of shortage of fossil fuel supplies and climate warming triggered by excessive carbon dioxide emission, alternative resources for chemical industry have gained considerable attention. Renewable resources and their derivatives are of particular interest. Glycerol, which constitutes one of the by-products during biodiesel production, is such a substrate. Thus, generated excess glycerol may become an environmental problem, since it cannot be disposed of in the environment. The most promising products obtained from glycerol are polyols, including 1,3-propanediol, an important substrate in the production of synthetic materials, e.g. polyurethanes, unsaturated polyesters, and epoxy resins. Glycerol can be used as a carbon and energy source for microbial growth in industrial microbiology to produce 1,3-propanediol. This paper is a review of metabolic pathways of native producers and E. coli with the acquired ability to produce the diol via genetic manipulations. Culture conditions during 1,3-PDO production and genetic modifications of E. coil used in order to increase efficiency of glycerol bioconversion are also described in this paper.
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