期刊
IRISH JOURNAL OF MEDICAL SCIENCE
卷 180, 期 1, 页码 115-119出版社
SPRINGER LONDON LTD
DOI: 10.1007/s11845-010-0550-y
关键词
Vitamin D; Female; Women; Ireland; Deficiency; Parathyroid hormone
Increasing attention has been focused on diseases associated with ageing, as the mean age of the population in developed countries increases. Vitamin D and parathyroid hormone play key roles in calcium homeostasis, which is integral to skeletal health. To assess the vitamin D status of healthy, community dwelling, middle-aged and older females. General biochemistry and bone profiles, including ALP, PTH and 25(OH)D, were determined. Of 143 healthy white women receiving no supplementation or bone modifying treatments, 47% were vitamin D insufficient (< 50 nmol/L) and only 4% were sufficient for the time of year. There was no statically significant correlation between age and 25(OH)D concentrations; neither was there a statistically significant seasonal variation in 25(OH)D levels noted. Vitamin D status should be assessed more often in middle-aged and older females. Expected age-related and seasonal variations in 25(OH)D levels were not confirmed in this study.
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